| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tamar Kolodny, Michael-Paul Schallmo, Jennifer Gerdts, Richard A E Edden, Raphael A Bernier, Scott O Murra. Concentrations of Cortical GABA and Glutamate in Young Adults With Autism Spectrum Disorder. Autism research : official journal of the International Society for Autism Research. vol 13. issue 7. 2021-06-16. PMID:32297709. |
we used edited magnetic resonance spectroscopy (mrs) to quantify signals associated with both gaba and the excitatory neurotransmitter glutamate in multiple regions of the sensory and sensorimotor cortex, including primary visual, auditory, and motor areas in adult individuals with autism and in neurotypical controls. |
2021-06-16 |
2023-08-13 |
human |
| Tamar Kolodny, Michael-Paul Schallmo, Jennifer Gerdts, Richard A E Edden, Raphael A Bernier, Scott O Murra. Concentrations of Cortical GABA and Glutamate in Young Adults With Autism Spectrum Disorder. Autism research : official journal of the International Society for Autism Research. vol 13. issue 7. 2021-06-16. PMID:32297709. |
we conclude that levels of gaba and glx (glutamate, glutamine, and glutathione) in the sensory and sensorimotor cortex, as measured with mrs at 3t, are comparable in adults with autism and neurotypical individuals. |
2021-06-16 |
2023-08-13 |
human |
| Sebastian M Frank, Lisa Forster, Maja Pawellek, Wilhelm M Malloni, Sinyeob Ahn, Peter U Tse, Mark W Greenle. Visual Attention Modulates Glutamate-Glutamine Levels in Vestibular Cortex: Evidence from Magnetic Resonance Spectroscopy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 9. 2021-06-11. PMID:33452222. |
by using functional magnetic resonance spectroscopy in a group of female and male subjects, we find that attention to visual motion downregulates in a load-dependent manner the concentration of excitatory neurotransmitter (glutamate and its precursor glutamine, referred to together as glx) within the parietoinsular vestibular cortex (pivc), a core cortical area of the vestibular system, while leaving the concentration of inhibitory neurotransmitter (gaba) in pivc unchanged. |
2021-06-11 |
2023-08-13 |
human |
| Colleen McSweeney, Fengping Dong, Miranda Chen, Jessica Vitale, Li Xu, Nicole Crowley, Bernhard Luscher, Donghua Zou, Yingwei Ma. Full function of exon junction complex factor, Rbm8a, is critical for interneuron development. Translational psychiatry. vol 10. issue 1. 2021-05-18. PMID:33154347. |
consistently, neurons in the cortex of conditional knockout (cko) mice show a significant decrease in gaba frequency. |
2021-05-18 |
2023-08-13 |
mouse |
| Tiffany Hong, Carmen Falcone, Brett Dufour, Sarwat Amina, Rosalia Perez Castro, Jade Regalado, Weston Pearson, Stephen C Noctor, Verónica Martínez-Cerdeñ. GABA Neuroscience. vol 437. 2021-05-14. PMID:32335215. |
gaba some forms of autism spectrum disorder, a neurodevelopmental syndrome characterized by impaired communication and social skills as well as repetitive behaviors, are purportedly associated with dysregulation of the excitation/inhibition balance in the cerebral cortex. |
2021-05-14 |
2023-08-13 |
human |
| Amgad Droby, Lazar Fleysher, Maria Petracca, Kornelius Podranski, Junqian Xu, Michelle Fabian, Malgorzata Marjańska, Matilde Ingles. Lower cortical gamma-aminobutyric acid level contributes to increased connectivity in sensory-motor regions in progressive MS. Multiple sclerosis and related disorders. vol 43. 2021-05-14. PMID:32480344. |
low concentration of gamma-aminobutyric acid (gaba) was observed in the sensorimotor cortex (smc) of these patients and was associated with reduced motor functions of limbs. |
2021-05-14 |
2023-08-13 |
Not clear |
| Bradley R King, Jost-Julian Rumpf, Elvire Verbaanderd, Kirstin F Heise, Nina Dolfen, Stefan Sunaert, Julien Doyon, Joseph Classen, Dante Mantini, Nicolaas A J Puts, Richard A E Edden, Geneviève Albouy, Stephan P Swinne. Baseline sensorimotor GABA levels shape neuroplastic processes induced by motor learning in older adults. Human brain mapping. vol 41. issue 13. 2021-05-14. PMID:32583940. |
previous research in young adults has demonstrated that both motor learning and transcranial direct current stimulation (tdcs) trigger decreases in the levels of gamma-aminobutyric acid (gaba) in the sensorimotor cortex, and these decreases are linked to greater learning. |
2021-05-14 |
2023-08-13 |
human |
| Tiffany Bell, Mehak Stokoe, Akashroop Khaira, Megan Webb, Melanie Noel, Farnaz Amoozegar, Ashley D Harri. GABA and glutamate in pediatric migraine. Pain. vol 162. issue 1. 2021-05-14. PMID:33326202. |
lower gaba levels in the sensorimotor cortex were associated with being closer to their next migraine attack. |
2021-05-14 |
2023-08-13 |
Not clear |
| Shi-Yu Peng, Zhe Shi, Dong-Sheng Zhou, Xin-Yue Wang, Xing-Xing Li, Xiao-Li Liu, Wei-Di Wang, Guan-Ning Lin, Bing-Xing Pan, Valerie Voon, Anthony A Grace, Markus Heilig, Ma-Li Wong, Ti-Fei Yua. Reduced motor cortex GABA Molecular psychiatry. vol 26. issue 2. 2021-05-14. PMID:33432190. |
reduced motor cortex gaba the gaba |
2021-05-14 |
2023-08-13 |
Not clear |
| Feng Gu, Isabel Parada, Tao Yang, Frank M Longo, David A Princ. Partial Activation of TrkB Receptors Corrects Interneuronal Calcium Channel Dysfunction and Reduces Epileptogenic Activity in Neocortex following Injury. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 9. 2021-05-13. PMID:32488246. |
chronic bd treatment 1) upregulated n and p/q channel immunoreactivity in gabaergic terminals; 2) increased the effects of n or p/q channel blockade on evoked inhibitory postsynaptic currents (eipscs); 3) increased gaba release probability and the frequency of sipscs; and 4) reduced the incidence of epileptiform discharges in uc cortex. |
2021-05-13 |
2023-08-13 |
Not clear |
| Mohammad I K Hamad, Abdalrahim Jbara, Obada Rabaya, Petya Petrova, Solieman Daoud, Nesrine Melliti, Maurice Meseke, David Lutz, Elisabeth Petrasch-Parwez, Jan Claudius Schwitalla, Melanie D Mark, Stefan Herlitze, Gebhard Reiss, Joachim Herz, Eckart Förste. Reelin signaling modulates GABA Journal of neurochemistry. vol 156. issue 5. 2021-05-04. PMID:32083308. |
reelin signaling modulates gaba reelin is a protein that is best known for its role in controlling neuronal layer formation in the developing cortex. |
2021-05-04 |
2023-08-13 |
Not clear |
| K Heimrath, A Brechmann, R Blobel-Lüer, J Stadler, E Budinger, Tino Zaehl. Transcranial direct current stimulation (tDCS) over the auditory cortex modulates GABA and glutamate: a 7 T MR-spectroscopy study. Scientific reports. vol 10. issue 1. 2021-04-22. PMID:33208867. |
transcranial direct current stimulation (tdcs) over the auditory cortex modulates gaba and glutamate: a 7 t mr-spectroscopy study. |
2021-04-22 |
2023-08-13 |
human |
| Swati Sahoo, Prashant S Kharkar, Niteshkumar U Sahu, Brijesh . Anxiolytic activity of Psidium guajava in mice subjected to chronic restraint stress and effect on neurotransmitters in brain. Phytotherapy research : PTR. vol 35. issue 3. 2021-04-19. PMID:33034100. |
neurotransmitters such as monoamines (serotonin, norepinephrine, and dopamine), γ-aminobutyric acid (gaba), and glutamate were estimated in different regions of the brain (cortex, hippocampus, and cerebellum and brain stem). |
2021-04-19 |
2023-08-13 |
mouse |
| Georg Northoff, Dusan Hirjak, Robert C Wolf, Paola Magioncalda, Matteo Martin. All roads lead to the motor cortex: psychomotor mechanisms and their biochemical modulation in psychiatric disorders. Molecular psychiatry. vol 26. issue 1. 2021-04-14. PMID:32555423. |
these include: (i) modulation of dopamine- and substantia nigra-based subcortical-cortical motor circuit by primarily non-motor subcortical raphe nucleus and serotonin via basal ganglia and thalamus (as well as by other neurotransmitters like glutamate and gaba); (ii) modulation of motor cortex and motor network by non-motor cortical networks like default-mode network and sensory networks; (iii) global activity in cortex may also shape regional distribution of neural activity in motor cortex. |
2021-04-14 |
2023-08-13 |
human |
| Ryoki Sasaki, Naofumi Otsuru, Shota Miyaguchi, Sho Kojima, Hiraku Watanabe, Ken Ohno, Noriko Sakurai, Naoki Kodama, Daisuke Sato, Hideaki Onish. Influence of Brain-Derived Neurotrophic Factor Genotype on Short-Latency Afferent Inhibition and Motor Cortex Metabolites. Brain sciences. vol 11. issue 3. 2021-04-13. PMID:33804682. |
furthermore, the considerable inter-individual variability in inhibitory network activity typically measured by tms may be affected not only by gaba but also by other pathways, including glutamatergic and cholinergic activities; therefore, we used 3-t magnetic resonance spectroscopy (mrs) to measure the dynamics of glutamate plus glutamine (glx) and choline concentrations in the left m1, left somatosensory cortex, and right cerebellum. |
2021-04-13 |
2023-08-13 |
human |
| Jens V Andersen, Emil Jakobsen, Emil W Westi, Maria E K Lie, Caroline M Voss, Blanca I Aldana, Arne Schousboe, Petrine Wellendorph, Lasse K Bak, Lars H Pinborg, Helle S Waagepeterse. Extensive astrocyte metabolism of γ-aminobutyric acid (GABA) sustains glutamine synthesis in the mammalian cerebral cortex. Glia. vol 68. issue 12. 2021-04-06. PMID:32584476. |
extensive astrocyte metabolism of γ-aminobutyric acid (gaba) sustains glutamine synthesis in the mammalian cerebral cortex. |
2021-04-06 |
2023-08-13 |
mouse |
| Sónia C Correia, Nuno J Machado, Marco G Alves, Pedro F Oliveira, Paula I Moreir. Intermittent Hypoxic Conditioning Rescues Cognition and Mitochondrial Bioenergetic Profile in the Triple Transgenic Mouse Model of Alzheimer's Disease. International journal of molecular sciences. vol 22. issue 1. 2021-04-05. PMID:33466445. |
lastly, ihc also induced a marked reduction in synaptosomal-associated protein 25 kda (snap-25) levels and a significant increase in both glutamate and gaba levels in the brain cortex of 3×tg-ad mice, suggesting a remodeling of the synaptic microenvironment. |
2021-04-05 |
2023-08-13 |
mouse |
| Xiaoli Xing, Juan Fu, Hongbo Wang, Xigeng Zhen. Contributions of prelimbic cortex, dorsal and ventral hippocampus, and basolateral amygdala to fear return induced by elevated platform stress in rats. Brain research. vol 1761. 2021-03-21. PMID:33662338. |
the contributions of the prelimbic cortex (pl), dorsal hippocampus (dh), ventral hippocampus (vh), and basolateral amygdala (bla) were examined by targeted bilateral intracerebral injection of the gaba |
2021-03-21 |
2023-08-13 |
rat |
| Jiaxun Nie, Xiaoyan Wei, Xing Xu, Nanqin Li, Yuehan Li, Yonghua Zhao, Yun Guan, Feifei Ge, Xiaowei Gua. Electro-acupuncture alleviates adolescent cocaine exposure-enhanced anxiety-like behaviors in adult mice by attenuating the activities of PV interneurons in PrL. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 34. issue 9. 2021-03-10. PMID:32683743. |
we recently found that adolescent cocaine exposure (ace) resulted in an enhancement of the γ-aminobutyric acid (gaba) neurotransmitter system in the prelimbic cortex (prl) of adult mice. |
2021-03-10 |
2023-08-13 |
mouse |
| Simon G J Dobri, Bernhard Ros. Total GABA level in human auditory cortex is associated with speech-in-noise understanding in older age. NeuroImage. vol 225. 2021-03-08. PMID:33099004. |
total gaba level in human auditory cortex is associated with speech-in-noise understanding in older age. |
2021-03-08 |
2023-08-13 |
human |