| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R C Collins, S Meht. Effect of amino-oxyacetic acid (AOAA) on focal penicillin seizures. Brain research. vol 157. issue 2. 1979-02-21. PMID:102408. |
at 20 mg/kg aoaa treatment results in a progressive 11 fold increase in gaba levels in cortex over three hours. |
1979-02-21 |
2023-08-11 |
rat |
| I Schmidt, I Eler, V P Fisenk. [Effect of clonazepam on neuronal activity in the sensomotor cortex of rat brain]. Farmakologiia i toksikologiia. vol 41. issue 6. 1979-02-21. PMID:720578. |
in tests on flaxedyl immobilized rats the effect of clonazepam on the action produced by gamma-aminobutyric acid, acetylcholine and l-glutamate, delivered microionophoretically to neurons of the sensomotor brain cortex, was investigated. |
1979-02-21 |
2023-08-11 |
rat |
| A A Aleksandro. [Intracellular study of the effect of GABA and taurine on neurons of the sensomotor cortex in cats]. Doklady Akademii nauk SSSR. vol 241. issue 6. 1979-01-26. PMID:710251. |
[intracellular study of the effect of gaba and taurine on neurons of the sensomotor cortex in cats]. |
1979-01-26 |
2023-08-11 |
Not clear |
| W E Haefel. Central actions of benzodiazepines: general introduction. The British journal of psychiatry : the journal of mental science. vol 133. 1978-12-20. PMID:212151. |
benzodiazepines enhance presynaptic inhibition in the spinal cord and dorsal column nuclei as well as postsynaptic inhibition in dorsal column nuclei, hippocampus, hypothalamus, cerebral cortex, cerebellar cortex, which are all examples of recurrent and collateral inhibition mediated by gaba ergic intrinsic neurones. |
1978-12-20 |
2023-08-11 |
Not clear |
| [3H]GABA transport into discrete subcellular fractions of the developing rat cortex: effect of methimazole. Proceedings of the Western Pharmacology Society. vol 21. 1978-12-02. PMID:29299. |
[3h]gaba transport into discrete subcellular fractions of the developing rat cortex: effect of methimazole. |
1978-12-02 |
2023-08-11 |
rat |
| G Toffano, A Guidotti, E Cost. Purification of an endogenous protein inhibitor of the high affinity binding of gamma-aminobutyric acid to synaptic membranes of rat brain. Proceedings of the National Academy of Sciences of the United States of America. vol 75. issue 8. 1978-12-02. PMID:279020. |
in a medium without na+, gamma-aminobutyric acid (gaba) binds at 0 degrees to freshly prepared crude synaptic membranes from rat cerebral cortex with an apparent dissociation constant of 218 nm. |
1978-12-02 |
2023-08-11 |
rat |
| R J Hitzeman. [3H]GABA transport into discrete subcellular fractions of the developing rat cortex: effect of methimazole. Proceedings of the Western Pharmacology Society. vol 21. 1978-12-02. PMID:693486. |
[3h]gaba transport into discrete subcellular fractions of the developing rat cortex: effect of methimazole. |
1978-12-02 |
2023-08-11 |
rat |
| A A Aleksandro. [Microiontophoretic study of the effect of GABA and taurine on the activity of cat motor cortex neurons]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. vol 64. issue 8. 1978-11-29. PMID:28963. |
[microiontophoretic study of the effect of gaba and taurine on the activity of cat motor cortex neurons]. |
1978-11-29 |
2023-08-11 |
cat |
| R N Englander, R N Johnson, G R Hann. Ethosuximide and bicuculline inhibition in petit mal epilepsy. Neurologia, neurocirugia, psiquiatria. vol 18. issue 2-3 Suppl. 1978-11-29. PMID:99676. |
because gaba is thought to be the primary inhibitory transmitter in vl and cerebral cortex, bicuculline would be expected to result in disinhibition. |
1978-11-29 |
2023-08-11 |
cat |
| N Zisapel, N Zurgi. The content of GABA and other amino acids in bovine cerebral cortex synaptic vesicles. Life sciences. vol 23. issue 3. 1978-11-29. PMID:692255. |
the content of gaba and other amino acids in bovine cerebral cortex synaptic vesicles. |
1978-11-29 |
2023-08-11 |
cattle |
| K Nakamura, Y Shimokawa, Y Oikawa, K Nakamur. [Influence of clonazepam, an anticonvulsant benzodiazepine drug, on the rat brain monoamine containing neurons especially on dopaminergic neurons (author's transl)]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 74. issue 2. 1978-08-28. PMID:207628. |
these neurochemical and behavioral effects of clonazepam indicate probable postjunctional da stimulation in the striatum and cortex of the type not linked with adenylate cyclase and phosphodiesterase but probably due to activation of inhibitory gamma-amino butyric acid (gaba) neurons on the strio-nigral pathway. |
1978-08-28 |
2023-08-11 |
rat |
| G F Koob, M Del Fiacco, S D Iverse. Spontaneous and amphetamine-induced behavior after bilateral injection of ethanolamine-O-sulfate into the substantia nigra. Brain research. vol 146. issue 2. 1978-07-15. PMID:565665. |
gaba levels were significantly higher in substantia nigra, hypothalamus, corpus striatum and cerebral cortex 24 h following single or repeated (3 x) injections of 200 microgram/kg of eos into the zona reticulata of the sn. |
1978-07-15 |
2023-08-11 |
rat |
| I Das, J S de Belleroch. An assessment of the effect of hormone and neurotransmitters on adenine and guanine derivatives simultaneously in rat brain cortical slices. Experientia. vol 34. issue 3. 1978-05-08. PMID:204507. |
using incubated rat cerebral cortex slices it was shown that noradrenaline and acetylcholine stimulated camp and cgmp production respectively but glutamate and gamma-aminobutyric acid stimulated production of both cyclic nucleotides. |
1978-05-08 |
2023-08-11 |
rat |
| V Chan-Pala. Autoradiographic localization of gamma-aminobutyric acid receptors in the rat central nervous system by using [3H]muscimol. Proceedings of the National Academy of Sciences of the United States of America. vol 75. issue 2. 1978-05-08. PMID:273213. |
as indicated by [(3)h]m binding and autoradiographic silver grains, gaba receptors display a laminar distribution over the cerebellar cortex, cerebral cortex, and hippocampus (in order of decreasing quantity); and a nonlaminar distribution in the caudate nucleus and substantia nigra. |
1978-05-08 |
2023-08-11 |
rat |
| F Valdés, F Orreg. Electrically induced, calcium-dependent release of endogenous GABA from rat brain cortex slices. Brain research. vol 141. issue 2. 1978-04-26. PMID:626907. |
electrically induced, calcium-dependent release of endogenous gaba from rat brain cortex slices. |
1978-04-26 |
2023-08-11 |
rat |
| E Somoza, F V DeFeudi. Correction factors for 'binding' studies; model systems for GABA binding to a synaptosomal-mitochondrial fraction of rat cerebral cortex. Journal of neurochemistry. vol 30. issue 1. 1978-03-21. PMID:621501. |
correction factors for 'binding' studies; model systems for gaba binding to a synaptosomal-mitochondrial fraction of rat cerebral cortex. |
1978-03-21 |
2023-08-11 |
rat |
| G Takagak. Sodium and potassium ions and accumulation of labelled D-aspartate and GABA in crude synaptosomal fraction from rat cerebral cortex. Journal of neurochemistry. vol 30. issue 1. 1978-03-21. PMID:621521. |
sodium and potassium ions and accumulation of labelled d-aspartate and gaba in crude synaptosomal fraction from rat cerebral cortex. |
1978-03-21 |
2023-08-11 |
rat |
| V V Zakusov, R U Ostrovskaya, S N Kozhechkin, V V Markovich, G M Molodavkin, T A Voronin. Further evidence for GABA-ergic mechanisms in the action of benzodiazepines. Archives internationales de pharmacodynamie et de therapie. vol 229. issue 2. 1978-02-18. PMID:23084. |
diazepam enhances the inhibitory effect of gaba applied iontophoretically to rabbit sensorymotor cortex neurons. |
1978-02-18 |
2023-08-11 |
rat |
| N R Liebowitz, T A Pedley, R W Cutle. Release of gamma-aminobutyric acid from hippocampal slices of the rat following generalized seizures induced by daily electrical stimulation of entorhinal cortex. Brain research. vol 138. issue 2. 1978-02-18. PMID:589482. |
release of gamma-aminobutyric acid from hippocampal slices of the rat following generalized seizures induced by daily electrical stimulation of entorhinal cortex. |
1978-02-18 |
2023-08-11 |
rat |
| C M Gauchy, L L Iversen, T M Jessel. The spontaneous and evoked release of newly synthesized [14C]GABA from rat cerebral cortex, in vitro. Brain research. vol 138. issue 2. 1978-02-18. PMID:589483. |
the spontaneous and evoked release of newly synthesized [14c]gaba from rat cerebral cortex, in vitro. |
1978-02-18 |
2023-08-11 |
rat |