| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S H Hendry, E G Jone. Sizes and distributions of intrinsic neurons incorporating tritiated GABA in monkey sensory-motor cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 1. issue 4. 1981-10-29. PMID:7264726. |
neurons accumulating [3h]gamma-aminobutyric acid (gaba) were identified autoradiographically in frozen and plastic sections after injection of the material in the monkey somatic sensory (areas 3, 1, and 2), motor (area 4), and parietal (area 5) cortex following intravenous administration of a gaba transaminase inhibitor, amino-oxyacetic acid. |
1981-10-29 |
2023-08-12 |
monkey |
| J R Unnerstall, M J Kuhar, D L Niehoff, J M Palacio. Benzodiazepine receptors are coupled to a subpopulation of gamma-aminobutyric acid (GABA) receptors: evidence from a quantitative autoradiographic study. The Journal of pharmacology and experimental therapeutics. vol 218. issue 3. 1981-10-25. PMID:6267249. |
in serial sections, striking differences were observed in the distribution of high affinity gaba and bz receptors in areas such as the cerebral cortex, globus pallidus, thalamus, hypothalamus and cerebellar cortex. |
1981-10-25 |
2023-08-12 |
rat |
| W F White, M A Dichter, S R Snodgras. Benzodiazepine binding and interactions with the GABA receptor complex in living cultures of rat cerebral cortex. Brain research. vol 215. issue 1-2. 1981-10-14. PMID:6114777. |
benzodiazepine binding and interactions with the gaba receptor complex in living cultures of rat cerebral cortex. |
1981-10-14 |
2023-08-12 |
rat |
| F Moroni, R Corradetti, F Casamenti, G Moneti, G Pepe. The release of endogenous GABA and glutamate from the cerebral cortex in the rat. Naunyn-Schmiedeberg's archives of pharmacology. vol 316. issue 3. 1981-09-25. PMID:7254366. |
the release of endogenous gaba and glutamate from the cerebral cortex in the rat. |
1981-09-25 |
2023-08-12 |
rat |
| F Moroni, R Corradetti, F Casamenti, G Moneti, G Pepe. The release of endogenous GABA and glutamate from the cerebral cortex in the rat. Naunyn-Schmiedeberg's archives of pharmacology. vol 316. issue 3. 1981-09-25. PMID:7254366. |
the release of endogenous gaba and glutamate from the cerebral cortex was measured using a cortical cup technique in unanaesthetized freely moving rats and anaesthetized rats by means of a sensitive and specific mass-spectrometric procedure. |
1981-09-25 |
2023-08-12 |
rat |
| F Moroni, R Corradetti, F Casamenti, G Moneti, G Pepe. The release of endogenous GABA and glutamate from the cerebral cortex in the rat. Naunyn-Schmiedeberg's archives of pharmacology. vol 316. issue 3. 1981-09-25. PMID:7254366. |
when the dura was removed, a high k+ solution placed on the exposed cerebral cortex elicited a 7--8 fold increase in gaba output accompanied by a marked decrease in glutamate output and by ecog synchronization. |
1981-09-25 |
2023-08-12 |
rat |
| F Moroni, R Corradetti, F Casamenti, G Moneti, G Pepe. The release of endogenous GABA and glutamate from the cerebral cortex in the rat. Naunyn-Schmiedeberg's archives of pharmacology. vol 316. issue 3. 1981-09-25. PMID:7254366. |
it is concluded that gaba and glutamate released from the cerebral cortex and diffused into an epidural or cortical cup originate at least in part from the brain. |
1981-09-25 |
2023-08-12 |
rat |
| R Hofstein, B Barnett, D Samue. The effect of anti-synaptosomal membrane antibodies of neurotransmitter uptake. Journal of neurochemistry. vol 37. issue 1. 1981-09-22. PMID:6114132. |
antibodies raised against synaptosomal plasma membranes of rat hippocampus (anti-hpc igg) caused inhibition of [3h]noradrenaline, [3h]5-hydroxytryptamine, [3h]gaba and [3h]aspartate uptake into s1 fractions and slices of hippocampus and cerebral cortex, but not those of caudate nucleus and hypothalamus. |
1981-09-22 |
2023-08-12 |
rat |
| C R Gardner, M H Richards, J Grov. Effects of GABA metabolism on [3H]-GABA transport in synaptosomal preparations from rat cerebral cortex. Advances in biochemical psychopharmacology. vol 29. 1981-09-15. PMID:7257924. |
effects of gaba metabolism on [3h]-gaba transport in synaptosomal preparations from rat cerebral cortex. |
1981-09-15 |
2023-08-12 |
rat |
| S C Cheng, E A Brunne. Inhibition of GABA metabolism in rat brain slices by halothane. Anesthesiology. vol 55. issue 1. 1981-08-20. PMID:6787953. |
based on studies with rat cerebral cortex slices, it was previously hypothesized that halothane anesthesia may result from increased gaba (gamma-aminobutyric acid) content in the synapses. |
1981-08-20 |
2023-08-12 |
rat |
| S C Cheng, E A Brunne. Inhibition of GABA metabolism in rat brain slices by halothane. Anesthesiology. vol 55. issue 1. 1981-08-20. PMID:6787953. |
the increase in gaba content could arise from several possible causes which are examined in this study using rat cerebral cortex slices as a model. |
1981-08-20 |
2023-08-12 |
rat |
| F Baldino, H M Gelle. Sodium valproate enhancement of gamma-aminobutyric acid (GABA) inhibition: electrophysiological evidence for anticonvulsant activity. The Journal of pharmacology and experimental therapeutics. vol 217. issue 2. 1981-07-09. PMID:6785416. |
the effects of valproate on spontaneous neuronal activity and its interaction with locally applied gamma-aminobutyric acid (gaba) were assessed in the rat cerebral cortex. |
1981-07-09 |
2023-08-12 |
rat |
| F Baldino, H M Gelle. Sodium valproate enhancement of gamma-aminobutyric acid (GABA) inhibition: electrophysiological evidence for anticonvulsant activity. The Journal of pharmacology and experimental therapeutics. vol 217. issue 2. 1981-07-09. PMID:6785416. |
our results indicate that valproate enhances gaba inhibition in the cerebral cortex, an action which is independent of its effect on spontaneous activity. |
1981-07-09 |
2023-08-12 |
rat |
| M A Rea, W J McBride, B H Rohd. Levels of glutamate, aspartate, GABA, and taurine in different regions of the cerebellum after x-irradiation-induced neuronal loss. Neurochemical research. vol 6. issue 1. 1981-06-23. PMID:7219665. |
the levels of glutamate (glu), aspartate (asp), gamma-amino-n-butyric acid (gaba), and taurine (tau) were determined in the cortex, molecular layer, and deep nuclei of cerebella of adult rats exposed to x-irradiation at 12-15 days following birth (to prevent the acquisition of late-forming granule cells; 12-15x group) and 8-15 days following birth (to prevent the acquisition of granule and stellate cells; 8-15x group). |
1981-06-23 |
2023-08-12 |
rat |
| R A Bakay, A B Harri. Neurotransmitter, receptor and biochemical changes in monkey cortical epileptic foci. Brain research. vol 206. issue 2. 1981-06-13. PMID:6111378. |
the epileptic cortex demonstrated markedly reduced gaba receptor binding and diminished tissue gaba concentration and gad activity. |
1981-06-13 |
2023-08-12 |
monkey |
| M K Ticku, R D Huffma. The effects of acute and chronic morphine administration on GABA receptor binding. European journal of pharmacology. vol 68. issue 2. 1981-05-28. PMID:6258932. |
acute morphine (25 mg/kg) administration produced a decrease in the gaba binding in cerebellum, cortex and striatum. |
1981-05-28 |
2023-08-12 |
rat |
| T W Stone, C Hollins, H Lloy. Methylxanthines modulate adenosine release from slices of cerebral cortex. Brain research. vol 207. issue 2. 1981-05-26. PMID:6162526. |
using slices of mouse or rat cerebral cortex incubated with [3h]adenosine or [3h]adenine and/or [14c]gaba we have examined factors affecting the release of these compounds, and especially the influence of methylxanthines. |
1981-05-26 |
2023-08-12 |
mouse |
| B R Lester, A L Miller, E J Pec. Differential solubilization of gamma-aminobutyric acid receptive sites from membranes of mammalian brain. Journal of neurochemistry. vol 36. issue 1. 1981-04-24. PMID:6257843. |
sodium-dependent (+na) and sodium-independent (-na) receptive sites for gamma-aminobutyric acid (gaba) residing in or on frozen synaptic plasma membranes (spm) of bovine cerebral cortex were characterized as to binding constants, pharmacologic specificities, and sodium dependence. |
1981-04-24 |
2023-08-12 |
cattle |
| R H Ng, B D Howar. Inhibition by neurotoxic phospholipases A2 of synaptosomal uptake of gamma-aminobutyric acid. Journal of neurochemistry. vol 36. issue 1. 1981-04-24. PMID:7463056. |
a comparison has been made of the abilities of several neurotoxic and nontoxic phospholipases a2 from snake venoms to inhibit the intake of gamma-aminobutyric acid into synaptosomes from rat cerebral cortex. |
1981-04-24 |
2023-08-12 |
rat |
| P N Patsalos, P T Lascelle. Changes in regional brain levels of amino acid putative neurotransmitters after prolonged treatment with the anticonvulsant drugs diphenylhydantoin, phenobarbitone, sodium valproate, ethosuximide, and sulthiame in the rat. Journal of neurochemistry. vol 36. issue 2. 1981-04-13. PMID:6109766. |
phenobarbitone significantly elevated gaba concentrations in all brain regions, while taurine concentration was only elevated in the cerebral cortex. |
1981-04-13 |
2023-08-12 |
rat |