| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Núria de Vera, Lluïsa Camón, Emili Martíne. Putrescine as a marker of the effects of 2-chloropropionic acid in the rat brain. Neuroscience letters. vol 362. issue 3. 2004-07-19. PMID:15158016. |
the neurotoxin 2-chloropropionic acid (2cpa, 750 mg/kg, per os) induces ataxia in rats causing neuropathological changes (necrosis and edema) localized mainly in the cerebellum (cb). |
2004-07-19 |
2023-08-12 |
rat |
| Susanne M Morton, Amy J Bastia. Cerebellar control of balance and locomotion. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 10. issue 3. 2004-07-16. PMID:15155063. |
as such, one of the most characteristic signs of cerebellar damage is walking ataxia. |
2004-07-16 |
2023-08-12 |
Not clear |
| Andreas Fellgiebel, Thomas Siessmeier, Georg Winterer, Hartmut Lüddens, Klaus Mann, Lutz G Schmidt, Peter Bartenstei. Increased cerebellar PET glucose metabolism corresponds to ataxia in Wernicke-Korsakoff syndrome. Alcohol and alcoholism (Oxford, Oxfordshire). vol 39. issue 2. 2004-06-28. PMID:14998834. |
increased cerebellar pet glucose metabolism corresponds to ataxia in wernicke-korsakoff syndrome. |
2004-06-28 |
2023-08-12 |
Not clear |
| Andreas Fellgiebel, Thomas Siessmeier, Georg Winterer, Hartmut Lüddens, Klaus Mann, Lutz G Schmidt, Peter Bartenstei. Increased cerebellar PET glucose metabolism corresponds to ataxia in Wernicke-Korsakoff syndrome. Alcohol and alcoholism (Oxford, Oxfordshire). vol 39. issue 2. 2004-06-28. PMID:14998834. |
to investigate a possible relationship between cerebellar glucose metabolism and recovery from ataxia in the first months of acute wernicke-korsakoff syndrome. |
2004-06-28 |
2023-08-12 |
Not clear |
| Alfredo Brusco, Cinzia Gellera, Claudia Cagnoli, Alessandro Saluto, Alessia Castucci, Chiara Michielotto, Vincenza Fetoni, Caterina Mariotti, Nicola Migone, Stefano Di Donato, Franco Taron. Molecular genetics of hereditary spinocerebellar ataxia: mutation analysis of spinocerebellar ataxia genes and CAG/CTG repeat expansion detection in 225 Italian families. Archives of neurology. vol 61. issue 5. 2004-06-17. PMID:15148151. |
autosomal dominant cerebellar ataxias are a clinical and genetically heterogeneous group of progressive neurodegenerative diseases, at present associated with 22 loci (spinocerebellar ataxia [sca] 1-sca8, sca10-sca19, sca21, sca22, fibroblast growth factor 14 [fgf14]-sca, and dentatorubral-pallidoluysian atrophy [drpla]). |
2004-06-17 |
2023-08-12 |
Not clear |
| Ludger Schöls, Peter Bauer, Thorsten Schmidt, Thorsten Schulte, Olaf Ries. Autosomal dominant cerebellar ataxias: clinical features, genetics, and pathogenesis. The Lancet. Neurology. vol 3. issue 5. 2004-06-02. PMID:15099544. |
autosomal dominant cerebellar ataxias: clinical features, genetics, and pathogenesis. |
2004-06-02 |
2023-08-12 |
Not clear |
| Ludger Schöls, Peter Bauer, Thorsten Schmidt, Thorsten Schulte, Olaf Ries. Autosomal dominant cerebellar ataxias: clinical features, genetics, and pathogenesis. The Lancet. Neurology. vol 3. issue 5. 2004-06-02. PMID:15099544. |
autosomal dominant cerebellar ataxias are hereditary neurodegenerative disorders that are known as spinocerebellar ataxias (sca) in genetic nomenclature. |
2004-06-02 |
2023-08-12 |
Not clear |
| T Wollmann, A Nieto-Barco, F Montón-Alvarez, J Barroso-Riba. [Friedreich's ataxia: analysis of magnetic resonance imaging parameters and their correlates with cognitive and motor slowing]. Revista de neurologia. vol 38. issue 3. 2004-05-21. PMID:14963847. |
the heredodegenerative ataxias are a heterogeneous group of disorders affecting especially the cerebellum and its tracts. |
2004-05-21 |
2023-08-12 |
Not clear |
| H P Kremer, B P van de Warrenburg, R J Sink. [From gene to disease; autosomal dominant cerebellar ataxias]. Nederlands tijdschrift voor geneeskunde. vol 148. issue 13. 2004-05-20. PMID:15083626. |
[from gene to disease; autosomal dominant cerebellar ataxias]. |
2004-05-20 |
2023-08-12 |
Not clear |
| H P Kremer, B P van de Warrenburg, R J Sink. [From gene to disease; autosomal dominant cerebellar ataxias]. Nederlands tijdschrift voor geneeskunde. vol 148. issue 13. 2004-05-20. PMID:15083626. |
the autosomal dominant cerebellar ataxias (adcas) are a clinically homogeneous, yet genetically heterogeneous group of cerebellar neurodegenerative disorders for which at least 20 genes or loci have been identified to date. |
2004-05-20 |
2023-08-12 |
Not clear |
| C Lagier-Tourenne, E Boltshauser, N Breivik, M Gribaa, C Bétard, C Barbot, M Koeni. Homozygosity mapping of a third Joubert syndrome locus to 6q23. Journal of medical genetics. vol 41. issue 4. 2004-05-07. PMID:15060101. |
joubert syndrome (js) is a recessively inherited disorder characterised by hypotonia at birth and developmental delay, followed by truncal ataxia and cognitive impairment, characteristic neuroimaging findings (cerebellar vermis hypoplasia, "molar tooth sign") and suggestive facial features. |
2004-05-07 |
2023-08-12 |
Not clear |
| Lucy Anderson, Daniela Rossi, Jackie Linehan, Sebastian Brandner, Charles Weissman. Transgene-driven expression of the Doppel protein in Purkinje cells causes Purkinje cell degeneration and motor impairment. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 10. 2004-05-05. PMID:15007176. |
however, ubiquitous dpl overexpression in the brain of prp knockout mice correlated with ataxia and purkinje cell degeneration in the cerebellum. |
2004-05-05 |
2023-08-12 |
mouse |
| Delphine Simon, Hervé Seznec, Anne Gansmuller, Nadège Carelle, Philipp Weber, Daniel Metzger, Pierre Rustin, Michel Koenig, Hélène Pucci. Friedreich ataxia mouse models with progressive cerebellar and sensory ataxia reveal autophagic neurodegeneration in dorsal root ganglia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 8. 2004-04-30. PMID:14985441. |
friedreich ataxia mouse models with progressive cerebellar and sensory ataxia reveal autophagic neurodegeneration in dorsal root ganglia. |
2004-04-30 |
2023-08-12 |
mouse |
| H Jurgen Schelhaas, Bart P C van de Warrenburg, Gerard Hageman, Elly E Ippel, Monique van Hout, Berry Kreme. Cognitive impairment in SCA-19. Acta neurologica Belgica. vol 103. issue 4. 2004-04-15. PMID:15008504. |
the autosomal dominant cerebellar ataxias (adcas) are a heterogeneous group of neurodegenerative disorders characterised by progressive cerebellar dysfunction in combination with various associated features. |
2004-04-15 |
2023-08-12 |
Not clear |
| D Timmann, A Dimitrova, C Hein-Kropp, H Wilhelm, A Dörfle. Cerebellar agenesis: clinical, neuropsychological and MR findings. Neurocase. vol 9. issue 5. 2004-03-24. PMID:14972755. |
neurological examination revealed mild to moderate signs of cerebellar dysarthria, upper and lower limb ataxia and ataxia of stance and gait. |
2004-03-24 |
2023-08-12 |
Not clear |
| Giovanni Stevanin, Naima Bouslam, Stéphane Thobois, Hamid Azzedine, Lucas Ravaux, Anne Boland, Martin Schalling, Emmanuel Broussolle, Alexandra Dürr, Alexis Bric. Spinocerebellar ataxia with sensory neuropathy (SCA25) maps to chromosome 2p. Annals of neurology. vol 55. issue 1. 2004-03-12. PMID:14705117. |
autosomal dominant cerebellar ataxias constitute one of the most clinically, neuropathologically, and genetically heterogeneous groups of neurodegenerative disorders. |
2004-03-12 |
2023-08-12 |
human |
| Michel Koeni. Rare forms of autosomal recessive neurodegenerative ataxia. Seminars in pediatric neurology. vol 10. issue 3. 2004-03-08. PMID:14653406. |
the rarer recessive ataxias can be clinically classified as sensory and spinocerbellar ataxias, cerebellar ataxia with sensory-motor polyneuropathy, and purely cerebellar ataxias. |
2004-03-08 |
2023-08-12 |
Not clear |
| Bart P C van de Warrenburg, Nicolette C Notermans, Helenius J Schelhaas, Nens van Alfen, Richard J Sinke, Nine V A M Knoers, Machiel J Zwarts, Berry P H Kreme. Peripheral nerve involvement in spinocerebellar ataxias. Archives of neurology. vol 61. issue 2. 2004-03-08. PMID:14967775. |
in autosomal dominant cerebellar ataxias (adcas), it is unclear whether the associated peripheral nerve involvement is always a typical length-dependent axonopathy rather than primary neuronopathy due to neuronal degeneration in the spinal anterior horns and/or dorsal root ganglia. |
2004-03-08 |
2023-08-12 |
Not clear |
| Americo A Migliaccio, G Michael Halmagyi, Leigh A McGarvie, Phillip D Creme. Cerebellar ataxia with bilateral vestibulopathy: description of a syndrome and its characteristic clinical sign. Brain : a journal of neurology. vol 127. issue Pt 2. 2004-02-24. PMID:14607788. |
none has a family history of cerebellar or vestibular disease; spinocerebellar ataxia (sca) 1, 2, 3, 6, 7 and friedreich's ataxia were excluded by genetic testing. |
2004-02-24 |
2023-08-12 |
human |
| Ki-Hyung Kim, Jeoung-Hee Ha, Seung-Hyuk Chung, Chul-Tae Kim, Sun-Kyung Kim, Byung-Hwa Hyun, Kazuhiko Sawada, Yoshihiro Fukui, Il-Kwon Park, Geun-jwa Lee, Bum-Kyeong Kim, Nam-Seob Lee, Young-Gil Jeon. Glutamate and GABA concentrations in the cerebellum of novel ataxic mutant Pogo mice. Journal of veterinary science. vol 4. issue 3. 2004-02-24. PMID:14685024. |
in the present study, the cerebellar concentrations of glutamate and gaba were analyzed, since glutamate is a most prevalent excitatory neurotransmitter whereas gamma-aminobutyric acid (gaba) is one of the most abundant inhibitory neurotransmitters, which may be the main neurotransmitters related with the ataxia and epilepsy. |
2004-02-24 |
2023-08-12 |
mouse |