| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aaron D Smith, M Saeed Da. Mouse cerebellar nicotinic-cholinergic receptor modulation of Delta9-THC ataxia: role of the alpha4beta2 subtype. Brain research. vol 1115. issue 1. 2006-12-04. PMID:16934231. |
the results of the present investigation, therefore, strongly support involvement of the cerebellar alpha(4)beta(2), but not alpha(7), nicotinic receptor subtype in the mediation via nicotine and rjr-2403 on attenuation of delta(9)-thc ataxia. |
2006-12-04 |
2023-08-12 |
mouse |
| Yukiteru Maeda, Lisa Fujimura, Jiyang O-Wang, Masahiko Hatano, Akemi Sakamoto, Masafumi Arima, Masaaki Ebara, Hidetoshi Ino, Toshihide Yamashita, Hiromitsu Saisho, Takeshi Tokuhis. Role of Clast1 in development of cerebellar granule cells. Brain research. vol 1104. issue 1. 2006-11-30. PMID:16814752. |
the clast1-ko cerebellum with ataxia is small in size and revealed a severely aberrant lobulation, loss of the internal granule cell layer, and the disorganized purkinje cells. |
2006-11-30 |
2023-08-12 |
mouse |
| Y Ouyang, K Sakoe, H Shimazaki, M Namekawa, T Ogawa, Y Ando, T Kawakami, J Kaneko, Y Hasegawa, K Yoshizawa, T Amino, K Ishikawa, H Mizusawa, I Nakano, Y Takiyam. 16q-linked autosomal dominant cerebellar ataxia: a clinical and genetic study. Journal of the neurological sciences. vol 247. issue 2. 2006-10-31. PMID:16780885. |
the autosomal dominant cerebellar ataxias (adcas) comprise a genetically and clinically heterogenous group of neurodegenerative disorders. |
2006-10-31 |
2023-08-12 |
Not clear |
| O Blanco-Múñez, A Suárez-Gauthier, H Martín-García, V Díaz-Konrad, V San Antonio-Román, A Cabell. [Unusual cortical compromise in a case of Wernicke's encephalopathy]. Revista de neurologia. vol 42. issue 10. 2006-10-18. PMID:16703527. |
symptoms of we include ophthalmoplegia, nistagmus, ataxia and mental confusion; post-mortem examination shows characteristic symmetrical lesions in the mamillary bodies (mb), hypothalamus, thalamus, brain stem and cerebellum with spongiosis, demyelination, vascular proliferation and relative preservation of neurons. |
2006-10-18 |
2023-08-12 |
Not clear |
| I Pascual-Castroviejo, S I Pascual-Pascual, S Quijano-Roy, M Gutiérrez-Molina, M C Morales, R Velázquez-Fragua, M Matie. [Cerebellar ataxia of Norman-Jaeken. Presentation of seven Spanish patients]. Revista de neurologia. vol 42. issue 12. 2006-10-18. PMID:16775797. |
to show that the cerebellar ataxias described by norman and by jaeken (cdg1a) are the same disease. |
2006-10-18 |
2023-08-12 |
Not clear |
| Lausanne P Carron, C Bellini, M Reichhart, A Bonett. [Cerebellar abscess--unusual reason for ataxia in an alcoholic patient]. Praxis. vol 95. issue 27-28. 2006-10-16. PMID:16888928. |
[cerebellar abscess--unusual reason for ataxia in an alcoholic patient]. |
2006-10-16 |
2023-08-12 |
Not clear |
| Lausanne P Carron, C Bellini, M Reichhart, A Bonett. [Cerebellar abscess--unusual reason for ataxia in an alcoholic patient]. Praxis. vol 95. issue 27-28. 2006-10-16. PMID:16888928. |
a 45-year-old alcoholic man showing an acute ataxia followed by a central respiratory arrest caused by multiple cerebellar abscesses is hospitalised. |
2006-10-16 |
2023-08-12 |
Not clear |
| S Gilman, S J May, C W Shults, C M Tanner, W Kukull, V M-Y Lee, E Masliah, P Low, P Sandroni, J Q Trojanowski, L Ozelius, T Forou. The North American Multiple System Atrophy Study Group. Journal of neural transmission (Vienna, Austria : 1996). vol 112. issue 12. 2006-10-12. PMID:16284910. |
most patients among the 87 had parkinsonian features, which frequently began asymmetrically and remained asymmetrical; one-third responded to levodopa and many developed levodopa complications; almost two-thirds of the patients had cerebellar dysfunction, of these 90% had ataxia; urinary incontinence occurred commonly, and sleep disorders affected most. |
2006-10-12 |
2023-08-12 |
Not clear |
| A Blanco, R Moyano, J Vivo, R Flores-Acuña, A Molina, C Blanco, J G Monterd. Purkinje cell apoptosis in arabian horses with cerebellar abiotrophy. Journal of veterinary medicine. A, Physiology, pathology, clinical medicine. vol 53. issue 6. 2006-10-10. PMID:16901270. |
purkinje cerebellar cells were studied in three arabian horses aged between 6 and 8 months with clinical disorders in their movements, tremors and ataxia; the occurrence of apoptosis in this cell population was investigated by the (terminal deoxynucleotidyl transferase biotin-dutp nick-end labelling (tunel) method. |
2006-10-10 |
2023-08-12 |
Not clear |
| I Thiffault, M F Rioux, M Tetreault, J Jarry, L Loiselle, J Poirier, F Gros-Louis, J Mathieu, M Vanasse, G A Rouleau, J P Bouchard, J Lesage, B Brai. A new autosomal recessive spastic ataxia associated with frequent white matter changes maps to 2q33-34. Brain : a journal of neurology. vol 129. issue Pt 9. 2006-10-04. PMID:16672289. |
the uncovering of the mutated gene may point to a common pathway for pyramidal and cerebellar degeneration as both are often observed in recessive ataxias and complicated paraplegias. |
2006-10-04 |
2023-08-12 |
Not clear |
| Susan Beckwitt Turkel, Virdette L Brumm, Wendy G Mitchell, C Jane Tavar. Mood and behavioral dysfunction with opsoclonus-myoclonus ataxia. The Journal of neuropsychiatry and clinical neurosciences. vol 18. issue 2. 2006-09-28. PMID:16720803. |
opsoclonus-myoclonus ataxia syndrome is a paraneoplastic syndrome of cerebellar damage associated with neuroblastoma. |
2006-09-28 |
2023-08-12 |
Not clear |
| Emiliano Biasini, Tania Massignan, Luana Fioriti, Valentina Rossi, Sara Dossena, Mario Salmona, Gianluigi Forloni, Valentina Bonetto, Roberto Chies. Analysis of the cerebellar proteome in a transgenic mouse model of inherited prion disease reveals preclinical alteration of calcineurin activity. Proteomics. vol 6. issue 9. 2006-09-13. PMID:16572473. |
these mice develop a progressive neurological syndrome characterized by ataxia and cerebellar atrophy due to synaptic degeneration in the molecular layer and massive apoptosis of granule neurons. |
2006-09-13 |
2023-08-12 |
mouse |
| Janet C Rucker, Joanna Jen, John S Stahl, Nandhitha Natesan, Robert W Baloh, R John Leig. Internuclear ophthalmoparesis in episodic ataxia type 2. Annals of the New York Academy of Sciences. vol 1039. 2006-09-08. PMID:15827025. |
while these findings might be specific to this mutation, ino in our patients with episodic ataxia type 2 suggested involvement outside the cerebellum, either in the brain-stem internuclear pathway or at the neuromuscular junction. |
2006-09-08 |
2023-08-12 |
human |
| Florence Frédéric, Colette Chianale, Charles Oliver, Jean Marian. Enhanced endocrine response to novel environment stress and lack of corticosterone circadian rhythm in staggerer (Rora sg/sg) mutant mice. Journal of neuroscience research. vol 83. issue 8. 2006-09-08. PMID:16555296. |
the homozygous rora sg/sg mutant mouse, of which the most obvious phenotype is ataxia associated with cerebellar degeneration, also overproduces inflammatory cytokines. |
2006-09-08 |
2023-08-12 |
mouse |
| W F Abdo, B P C van de Warrenburg, M Munneke, W J A van Geel, B R Bloem, H P H Kremer, M M Verbee. CSF analysis differentiates multiple-system atrophy from idiopathic late-onset cerebellar ataxia. Neurology. vol 67. issue 3. 2006-09-06. PMID:16894110. |
differentiating idiopathic late-onset cerebellar ataxia (iloca) from ataxia due to the cerebellar subtype of multiple-system atrophy (msa-c) can be difficult in the early stages of the disease |
2006-09-06 |
2023-08-12 |
Not clear |
| Li Zhou, Asuka Araki, Akinobu Nakano, Cem Sezer, Takayuki Harad. Different types of neural cell death in the cerebellum of the ataxia and male sterility (AMS) mutant mouse. Pathology international. vol 56. issue 4. 2006-08-18. PMID:16634962. |
different types of neural cell death in the cerebellum of the ataxia and male sterility (ams) mutant mouse. |
2006-08-18 |
2023-08-12 |
mouse |
| Li Zhou, Asuka Araki, Akinobu Nakano, Cem Sezer, Takayuki Harad. Different types of neural cell death in the cerebellum of the ataxia and male sterility (AMS) mutant mouse. Pathology international. vol 56. issue 4. 2006-08-18. PMID:16634962. |
to investigate the mechanisms(s) of age-dependent atrophy of the cerebellum of the ataxia and male sterility (ams) mouse at young age, the morphological changes were evaluated and the nature of neural cell death was examined. |
2006-08-18 |
2023-08-12 |
mouse |
| Esther Brusse, Inge de Koning, Anneke Maat-Kievit, Ben A Oostra, Peter Heutink, John C van Swiete. Spinocerebellar ataxia associated with a mutation in the fibroblast growth factor 14 gene (SCA27): A new phenotype. Movement disorders : official journal of the Movement Disorder Society. vol 21. issue 3. 2006-08-03. PMID:16211615. |
autosomal dominant cerebellar ataxias (adcas) are genetically classified into spinocerebellar ataxias (scas). |
2006-08-03 |
2023-08-12 |
Not clear |
| Hatem El-Shanti, Azhar Daoud, Ammar A Sadoon, Suzanne M Leal, Shan Chen, Kwanghyuk Lee, Ronald Spiege. A distinct autosomal recessive ataxia maps to chromosome 12 in an inbred family from Jordan. Brain & development. vol 28. issue 6. 2006-07-31. PMID:16376507. |
the four affected siblings have ataxia noted at the onset of walking with dysarthria and bulbar features, but no cerebellar hypoplasia on mri. |
2006-07-31 |
2023-08-12 |
Not clear |
| Catherine Grenier, Cyntia Bissonnette, Leonid Volkov, Xavier Rouco. Molecular morphology and toxicity of cytoplasmic prion protein aggregates in neuronal and non-neuronal cells. Journal of neurochemistry. vol 97. issue 5. 2006-07-21. PMID:16696854. |
recent studies have revealed that accumulation of prion protein (prp) in the cytoplasm results in the production of aggregates that are insoluble in non-ionic detergents and partially resistant to proteinase k. transgenic mice expressing prp in the cytoplasm develop severe ataxia with cerebellar degeneration and gliosis, suggesting that cytoplasmic prp may play a role in the pathogenesis of prion diseases. |
2006-07-21 |
2023-08-12 |
mouse |