| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eniko Sáfrány, László Balikó, András Guseo, Bernadett Faragó, Béla Meleg. [The autosomal dominant cerebellar ataxias are hereditary neurodegenerative diseases]. Orvosi hetilap. vol 148. issue 45. 2007-12-27. PMID:17984023. |
[the autosomal dominant cerebellar ataxias are hereditary neurodegenerative diseases]. |
2007-12-27 |
2023-08-12 |
Not clear |
| Tej K Pandit. A multifaceted role for ATM in genome maintenance. Expert reviews in molecular medicine. vol 5. issue 16. 2007-12-18. PMID:14987398. |
the pleiotropic nature of the clinical phenotypes of patients with ataxia-telangiectasia (a-t)--which encompass cerebellar degeneration (leading to ataxia), gonadal atrophy, and cancer predisposition--suggests multiple functions of the gene responsible for the disease. |
2007-12-18 |
2023-08-12 |
Not clear |
| J Gazulla, I Benavent. Single-blind, placebo-controlled pilot study of pregabalin for ataxia in cortical cerebellar atrophy. Acta neurologica Scandinavica. vol 116. issue 4. 2007-12-18. PMID:17824901. |
single-blind, placebo-controlled pilot study of pregabalin for ataxia in cortical cerebellar atrophy. |
2007-12-18 |
2023-08-12 |
rat |
| S Kaja, V Hann, H L Payne, C L Thompso. Aberrant cerebellar granule cell-specific GABAA receptor expression in the epileptic and ataxic mouse mutant, Tottering. Neuroscience. vol 148. issue 1. 2007-12-14. PMID:17614209. |
the mouse phenotype includes ataxia and intermittent myoclonic seizures which have been attributed to impaired excitatory neurotransmission at cerebellar granule cell (cgc) parallel fiber-purkinje cell (pf-pc) synapses [zhou yd, turner tj, dunlap k (2003) enhanced g-protein-dependent modulation of excitatory synaptic transmission in the cerebellum of the ca(2+)-channel mutant mouse, tottering. |
2007-12-14 |
2023-08-12 |
mouse |
| Po-Shan Wang, Ren-Shyan Liu, Bang-Hung Yang, Bing-Wen Soon. Topographic brain mapping of the international cooperative ataxia rating scale. A positron emission tomography study. Journal of neurology. vol 254. issue 6. 2007-12-07. PMID:17450320. |
the international cooperative ataxia rating scale (icars) is a 100-point semiquantitative scale designed primarily to assess cerebellar dysfunction. |
2007-12-07 |
2023-08-12 |
human |
| Po-Shan Wang, Ren-Shyan Liu, Bang-Hung Yang, Bing-Wen Soon. Topographic brain mapping of the international cooperative ataxia rating scale. A positron emission tomography study. Journal of neurology. vol 254. issue 6. 2007-12-07. PMID:17450320. |
we assessed the icars by rating the severity of cerebellar dysfunction in 27 patients with spinocerebellar ataxias (sca), three patients with sporadic olivopontocerebellar ataxia and 24 healthy control subjects. |
2007-12-07 |
2023-08-12 |
human |
| Maja Steinli. The cerebellum in cognitive processes: supporting studies in children. Cerebellum (London, England). vol 6. issue 3. 2007-12-06. PMID:17786820. |
in ataxia teleangiectasia, a neurodegenerative disorder affecting primarily the cerebellar cortex, a reduced verbal iq and problems of judgment of duration are a hint of the importance of the cerebellum in cognition. |
2007-12-06 |
2023-08-12 |
Not clear |
| Katrin Bür. Cognition in hereditary ataxia. Cerebellum (London, England). vol 6. issue 3. 2007-12-06. PMID:17786824. |
regarding the neuropathological pattern in different sca types, cognitive deficits in hereditary ataxias are not likely to be contingent upon cerebellar degeneration but to result from disruption of cerebrocerebellar circuitries at various levels in the cns. |
2007-12-06 |
2023-08-12 |
Not clear |
| Anja Weyer, Michael Abele, Tanja Schmitz-Hübsch, Beate Schoch, Markus Frings, Dagmar Timmann, Thomas Klockgethe. Reliability and validity of the scale for the assessment and rating of ataxia: a study in 64 ataxia patients. Movement disorders : official journal of the Movement Disorder Society. vol 22. issue 11. 2007-11-28. PMID:17516493. |
to this end, 64 patients with various ataxia disorders or stable cerebellar lesions were rated independently by two investigators. |
2007-11-28 |
2023-08-12 |
Not clear |
| Rajiv Devanagondi, Kiyoshi Egami, Mark S LeDoux, Ellen J Hess, H A Jinna. Neuroanatomical substrates for paroxysmal dyskinesia in lethargic mice. Neurobiology of disease. vol 27. issue 3. 2007-10-31. PMID:17561408. |
surgical removal of the cerebellum worsened ataxia but eliminated paroxysmal dyskinesias. |
2007-10-31 |
2023-08-12 |
mouse |
| J R Bretón Martínez, A Cánovas Martínez, S Casaña Pérez, J Escribá Alepuz, F Giménez Vázque. Mevalonic aciduria: report of two cases. Journal of inherited metabolic disease. vol 30. issue 5. 2007-10-25. PMID:17578678. |
in our patients, ataxia due to cerebellar atrophy and mental retardation have been the predominant clinical manifestations. |
2007-10-25 |
2023-08-12 |
human |
| Hongdi Meng, Sarah K Larson, Rui Gao, Xiaoxi Qia. BDNF transgene improves ataxic and motor behaviors in stargazer mice. Brain research. vol 1160. 2007-10-12. PMID:17588548. |
gross examination showed less severe ataxia with normal cerebellar cytoarchitecture in stg-bdnf mice than the original stg mice. |
2007-10-12 |
2023-08-12 |
mouse |
| Hongdi Meng, Sarah K Larson, Rui Gao, Xiaoxi Qia. BDNF transgene improves ataxic and motor behaviors in stargazer mice. Brain research. vol 1160. 2007-10-12. PMID:17588548. |
these results provide in vivo evidence for the correlation of the cerebellar bdnf levels to the ataxia and motor behaviors of stg mice. |
2007-10-12 |
2023-08-12 |
mouse |
| J Gazull. [An update on neurochemistry and pharmacological therapy of the cerebellar ataxias]. Revista de neurologia. vol 45. issue 1. 2007-10-09. PMID:17620264. |
[an update on neurochemistry and pharmacological therapy of the cerebellar ataxias]. |
2007-10-09 |
2023-08-12 |
Not clear |
| Anne Schaefer, Dónal O'Carroll, Chan Lek Tan, Dean Hillman, Mutsuyuki Sugimori, Rodolfo Llinas, Paul Greengar. Cerebellar neurodegeneration in the absence of microRNAs. The Journal of experimental medicine. vol 204. issue 7. 2007-09-17. PMID:17606634. |
deficiency in dicer is associated with progressive loss of mirnas, followed by cerebellar degeneration and development of ataxia. |
2007-09-17 |
2023-08-12 |
Not clear |
| S Comincini, V Ferrara, A Arias, A Malovini, A Azzalin, L Ferretti, E Benericetti, M Cardarelli, M Gerosa, M G Passarin, S Turazzi, R Bellazz. Diagnostic value of PRND gene expression profiles in astrocytomas: relationship to tumor grades of malignancy. Oncology reports. vol 17. issue 5. 2007-09-13. PMID:17390034. |
besides, doppel overexpression correlates with some prion-disease pathological features, such as ataxia and death of cerebellar neurons. |
2007-09-13 |
2023-08-12 |
Not clear |
| Cristina Deluca, Michele Tinazzi, Paolo Bovi, Nicolò Rizzuto, Giuseppe Morett. Limb ataxia and proximal intracranial territory brain infarcts: clinical and topographical correlations. Journal of neurology, neurosurgery, and psychiatry. vol 78. issue 8. 2007-09-10. PMID:17210622. |
limb ataxia is classically attributed to cerebellar hemispheric lesions, although isolated lesions of the inferior cerebellar peduncle (icp) in the medulla may also cause this sign. |
2007-09-10 |
2023-08-12 |
Not clear |
| Cristina Deluca, Michele Tinazzi, Paolo Bovi, Nicolò Rizzuto, Giuseppe Morett. Limb ataxia and proximal intracranial territory brain infarcts: clinical and topographical correlations. Journal of neurology, neurosurgery, and psychiatry. vol 78. issue 8. 2007-09-10. PMID:17210622. |
it is still unclear why only some patients with acute cerebellar infarcts in the posterior inferior cerebellar artery (pica) territory present with limb ataxia. |
2007-09-10 |
2023-08-12 |
Not clear |
| Aaron D Smith, M Saeed Da. Behavioral cross-tolerance between repeated intracerebellar nicotine and acute Delta(9)-tetrahydrocannabinol-induced cerebellar ataxia: role of cerebellar nitric oxide. The Journal of pharmacology and experimental therapeutics. vol 322. issue 1. 2007-08-30. PMID:17416741. |
presently, we have shown that intracerebellar nicotine (1.25, 2.5, and 5 ng; once daily for 5 days) and rjr-2403 (250, 500, and 750 ng; once daily for 5 days) significantly attenuate cerebellar delta(9)-thc-induced ataxia dose dependently, suggesting the development of cross-tolerance between nicotine or rjr-2403 with delta(9)-thc in male cd-1 mice. |
2007-08-30 |
2023-08-12 |
mouse |
| Aaron D Smith, M Saeed Da. Behavioral cross-tolerance between repeated intracerebellar nicotine and acute Delta(9)-tetrahydrocannabinol-induced cerebellar ataxia: role of cerebellar nitric oxide. The Journal of pharmacology and experimental therapeutics. vol 322. issue 1. 2007-08-30. PMID:17416741. |
the "nicotine or rjr-2403 + delta(9)-thc" treatments significantly increased cerebellar no(x) levels compared with treatment with delta(9)-thc alone, supporting a functional correlation between cerebellar nitric oxide production and cerebellar delta(9)-thc-induced ataxia and suggesting participation of nitric oxide in the observed cross-tolerance between nicotine/rjr-2403 and delta(9)-thc. |
2007-08-30 |
2023-08-12 |
mouse |