| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mario Manto, Daniele Marmolin. Animal models of human cerebellar ataxias: a cornerstone for the therapies of the twenty-first century. Cerebellum (London, England). vol 8. issue 3. 2009-11-09. PMID:19669387. |
animal models of human cerebellar ataxias: a cornerstone for the therapies of the twenty-first century. |
2009-11-09 |
2023-08-12 |
human |
| Mario Manto, Daniele Marmolin. Animal models of human cerebellar ataxias: a cornerstone for the therapies of the twenty-first century. Cerebellum (London, England). vol 8. issue 3. 2009-11-09. PMID:19669387. |
cerebellar ataxias represent a group of disabling neurological disorders. |
2009-11-09 |
2023-08-12 |
human |
| Mario Manto, Daniele Marmolin. Animal models of human cerebellar ataxias: a cornerstone for the therapies of the twenty-first century. Cerebellum (London, England). vol 8. issue 3. 2009-11-09. PMID:19669387. |
our understanding of the pathogenesis of cerebellar ataxias is continuously expanding. |
2009-11-09 |
2023-08-12 |
human |
| Mario Manto, Daniele Marmolin. Animal models of human cerebellar ataxias: a cornerstone for the therapies of the twenty-first century. Cerebellum (London, England). vol 8. issue 3. 2009-11-09. PMID:19669387. |
a considerable number of laboratory animals with neurological mutations have been reported and numerous relevant animal models mimicking the phenotype of cerebellar ataxias are becoming available. |
2009-11-09 |
2023-08-12 |
human |
| Mario Manto, Daniele Marmolin. Animal models of human cerebellar ataxias: a cornerstone for the therapies of the twenty-first century. Cerebellum (London, England). vol 8. issue 3. 2009-11-09. PMID:19669387. |
it is anticipated that the twenty-first century will be the century of effective therapies in the field of cerebellar ataxias. |
2009-11-09 |
2023-08-12 |
human |
| Ji Heon Hong, Oh Lyong Kim, Seong Ho Kim, Mi Young Lee, Sung Ho Jan. Cerebellar peduncle injury in patients with ataxia following diffuse axonal injury. Brain research bulletin. vol 80. issue 1-2. 2009-11-02. PMID:19505539. |
cerebellar peduncle injury in patients with ataxia following diffuse axonal injury. |
2009-11-02 |
2023-08-12 |
human |
| Ji Heon Hong, Oh Lyong Kim, Seong Ho Kim, Mi Young Lee, Sung Ho Jan. Cerebellar peduncle injury in patients with ataxia following diffuse axonal injury. Brain research bulletin. vol 80. issue 1-2. 2009-11-02. PMID:19505539. |
in the current study, we used dti to investigate cerebellar peduncle lesions of patients who showed severe ataxia following dai. |
2009-11-02 |
2023-08-12 |
human |
| Vikram G Shakkottai, Henry L Paulso. Physiologic alterations in ataxia: channeling changes into novel therapies. Archives of neurology. vol 66. issue 10. 2009-10-30. PMID:19822774. |
the ataxias constitute a heterogeneous group of diseases in which cerebellar dysfunction typically underlies the major neurologic manifestations. |
2009-10-30 |
2023-08-12 |
Not clear |
| M Yuzak. New (but old) molecules regulating synapse integrity and plasticity: Cbln1 and the delta2 glutamate receptor. Neuroscience. vol 162. issue 3. 2009-10-19. PMID:19124061. |
the delta2 glutamate receptor (glurdelta2) is predominantly expressed in cerebellar purkinje cells and plays crucial roles in cerebellar functions: glurdelta2-null mice display ataxia and impaired motor learning. |
2009-10-19 |
2023-08-12 |
mouse |
| P Hanusch, J Heyn, H Well, E Weninger, U Hasbargen, M Reh. [Peridural anaesthesia with ropivacaine for a patient with Friedrich's ataxia. Caesarean section after dorsal stabilisation of the spinal column (Th5-L1)]. Der Anaesthesist. vol 58. issue 7. 2009-10-05. PMID:19575167. |
friedreich's ataxia (fa) is a hereditary disease, which leads to degenerative changes in the spinal cord and cerebellum (incidence 1:50,000). |
2009-10-05 |
2023-08-12 |
Not clear |
| Wiljan J A J Hendriks, Gönül Dilaver, Yvet E Noordman, Berry Kremer, Jack A M Franse. PTPRR protein tyrosine phosphatase isoforms and locomotion of vesicles and mice. Cerebellum (London, England). vol 8. issue 2. 2009-09-30. PMID:19137382. |
elucidation of the molecular mechanisms by which ptprr deficiency imposes impairment of cerebellar neurons and motor coordination may provide candidate molecules for hereditary cerebellar ataxias that still await identification of the corresponding disease genes. |
2009-09-30 |
2023-08-12 |
mouse |
| Ina Schmitt, Emmanuelle Bitoun, Mario Mant. PTPRR, cerebellum, and motor coordination. Cerebellum (London, England). vol 8. issue 2. 2009-09-30. PMID:19488825. |
recent observations suggest that the human episodic ataxia 2 (ea2) and spinocerebellar ataxia types 6 (sca6), 12 (sca12), and 14 (sca14) might be associated with impaired phosphorylation levels of cerebellum calcium channels and receptors. |
2009-09-30 |
2023-08-12 |
mouse |
| Naoki Uchisaka, Naomi Takahashi, Masaki Sato, Akira Kikuchi, Shinji Mochizuki, Kohsuke Imai, Shigeaki Nonoyama, Osamu Ohara, Fumiaki Watanabe, Shuki Mizutani, Ryoji Hanada, Tomohiro Mori. Two brothers with ataxia-telangiectasia-like disorder with lung adenocarcinoma. The Journal of pediatrics. vol 155. issue 3. 2009-09-30. PMID:19732584. |
they both had ataxia with cerebellar atrophy and mental retardation. |
2009-09-30 |
2023-08-12 |
Not clear |
| Mario Manto, Daniele Marmolin. Cerebellar ataxias. Current opinion in neurology. vol 22. issue 4. 2009-09-25. PMID:19421057. |
cerebellar ataxias. |
2009-09-25 |
2023-08-12 |
Not clear |
| Mario Manto, Daniele Marmolin. Cerebellar ataxias. Current opinion in neurology. vol 22. issue 4. 2009-09-25. PMID:19421057. |
the term 'cerebellar ataxias' encompasses the various cerebellar disorders encountered during daily practice. |
2009-09-25 |
2023-08-12 |
Not clear |
| Veronica Bernard, Martina Minnerop, Katrin Bürk, Friedmar Kreuz, Gabriele Gillessen-Kaesbach, Christine Zühlk. Exon deletions and intragenic insertions are not rare in ataxia with oculomotor apraxia 2. BMC medical genetics. vol 10. 2009-09-24. PMID:19744353. |
the autosomal recessively inherited ataxia with oculomotor apraxia 2 (aoa2) is a neurodegenerative disorder characterized by juvenile or adolescent age of onset, gait ataxia, cerebellar atrophy, axonal sensorimotor neuropathy, oculomotor apraxia, and elevated serum afp levels. |
2009-09-24 |
2023-08-12 |
Not clear |
| Mohammed Faruq, Vinod Scaria, Inder Singh, Shivani Tyagi, Achal K Srivastava, Mitali Mukerj. SCA-LSVD: a repeat-oriented locus-specific variation database for genotype to phenotype correlations in spinocerebellar ataxias. Human mutation. vol 30. issue 7. 2009-09-23. PMID:19370769. |
repeat expansion has been implicated in 10 out of 17 candidate genes identified for autosomal dominant cerebellar ataxias (adcas)-commonly referred as spinocerebellar ataxias (scas). |
2009-09-23 |
2023-08-12 |
Not clear |
| Francesc Palau, Carmen Espinó. Autosomal recessive cerebellar ataxias. Orphanet journal of rare diseases. vol 1. 2009-09-22. PMID:17112370. |
autosomal recessive cerebellar ataxias. |
2009-09-22 |
2023-08-12 |
Not clear |
| Francesc Palau, Carmen Espinó. Autosomal recessive cerebellar ataxias. Orphanet journal of rare diseases. vol 1. 2009-09-22. PMID:17112370. |
autosomal recessive cerebellar ataxias (arca) are a heterogeneous group of rare neurological disorders involving both central and peripheral nervous system, and in some case other systems and organs, and characterized by degeneration or abnormal development of cerebellum and spinal cord, autosomal recessive inheritance and, in most cases, early onset occurring before the age of 20 years. |
2009-09-22 |
2023-08-12 |
Not clear |
| Wenbin Yang, Julie Cook, Benjamin Rassbach, Azucena Lemus, Stephen J DeArmond, James A Mastriann. A New Transgenic Mouse Model of Gerstmann-Straussler-Scheinker Syndrome Caused by the A117V Mutation of PRNP. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 32. 2009-09-08. PMID:19675240. |
gerstmann-sträussler-scheinker syndrome (gss) is a genetic prion disease typified clinically by the development of progressive ataxia and dementia, and histopathologically by the presence of prion protein (prp) amyloid plaques in the cns, especially within the cerebellum. |
2009-09-08 |
2023-08-12 |
mouse |