| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A M Libster, Y Lefler, A Yaron-Jakoubovitch, Y Yaro. Ataxia and the olivo-cerebellar module. Functional neurology. vol 25. issue 3. 2011-04-05. PMID:21232208. |
ataxia is a neurological symptom characterized by abnormal movement, due to cerebellar malfunction. |
2011-04-05 |
2023-08-12 |
Not clear |
| A M Libster, Y Lefler, A Yaron-Jakoubovitch, Y Yaro. Ataxia and the olivo-cerebellar module. Functional neurology. vol 25. issue 3. 2011-04-05. PMID:21232208. |
although the cause of the malfunction varies, from mutations in calcium or potassium channels to progressive degeneration of cerebellar tissue, the neurological symptoms of cerebellar-related ataxia are similar. |
2011-04-05 |
2023-08-12 |
Not clear |
| L Rinaldo, C Hanse. Ataxias and cerebellar dysfunction: involvement of synaptic plasticity deficits? Functional neurology. vol 25. issue 3. 2011-04-05. PMID:21232209. |
ataxias and cerebellar dysfunction: involvement of synaptic plasticity deficits? |
2011-04-05 |
2023-08-12 |
Not clear |
| Alexandra Schroeder, Ralf A Linker, Carsten Lukas, Peter H Kraus, Ralf Gol. Successful treatment of cerebellar ataxia and tremor in multiple sclerosis with topiramate: a case report. Clinical neuropharmacology. vol 33. issue 6. 2011-03-29. PMID:21079458. |
in conclusion, topiramate may be a new therapeutic option to treat cerebellar tremor and ataxia in patients with multiple sclerosis. |
2011-03-29 |
2023-08-12 |
Not clear |
| Steven U Walkley, Jakub Sikora, Matthew Micsenyi, Cristin Davidson, Kostantin Dobreni. Lysosomal compromise and brain dysfunction: examining the role of neuroaxonal dystrophy. Biochemical Society transactions. vol 38. issue 6. 2011-03-14. PMID:21118103. |
although neurons may be universally susceptible to nad, gabaergic neurons, particularly purkinje cells, appear most vulnerable and ataxia and related features of cerebellar dysfunction are a common outcome. |
2011-03-14 |
2023-08-12 |
Not clear |
| Claudia Cagnoli, Giovanni Stevanin, Alessandro Brussino, Marco Barberis, Cecilia Mancini, Russell L Margolis, Susan E Holmes, Marcello Nobili, Sylvie Forlani, Sergio Padovan, Patrizia Pappi, Cécile Zaros, Isabelle Leber, Pascale Ribai, Luisa Pugliese, Corrado Assalto, Alexis Brice, Nicola Migone, Alexandra Dürr, Alfredo Brusc. Missense mutations in the AFG3L2 proteolytic domain account for ∼1.5% of European autosomal dominant cerebellar ataxias. Human mutation. vol 31. issue 10. 2011-01-28. PMID:20725928. |
missense mutations in the afg3l2 proteolytic domain account for ∼1.5% of european autosomal dominant cerebellar ataxias. |
2011-01-28 |
2023-08-12 |
Not clear |
| Peter Mariën, Peggy Wackenier, Didier De Surgeloose, Peter P De Deyn, Jo Verhoeve. Developmental coordination disorder: disruption of the cerebello-cerebral network evidenced by SPECT. Cerebellum (London, England). vol 9. issue 3. 2011-01-25. PMID:20461488. |
as demonstrated by mild ataxia and a close semiological correspondence with the recently acknowledged 'cerebellar cognitive affective syndrome', clinical and neurocognitive investigations unambiguously indicated functional disruption of the cerebellum. |
2011-01-25 |
2023-08-12 |
Not clear |
| b' Robert Laforce, James P Buteau, Jean-Pierre Bouchard, Guy A Rouleau, R\\xc3\\xa9mi W Bouchard, Nicolas Dupr\\xc3\\xa. Cognitive impairment in ARCA-1, a newly discovered pure cerebellar ataxia syndrome. Cerebellum (London, England). vol 9. issue 3. 2011-01-25. PMID:20559786.' |
the goal of this study was to explore the role of the cerebellum in cognition and affect in patients with autosomal recessive cerebellar ataxia type 1 (arca-1), a newly described inherited cerebellar disease characterised by middle-age onset of ataxia as well as pure, severe and diffuse cerebellar atrophy. |
2011-01-25 |
2023-08-12 |
human |
| Isabelle Iltis, Diane Hutter, Khalaf O Bushara, H Brent Clark, Myron Gross, Lynn E Eberly, Christopher M Gomez, Gülin O. (1)H MR spectroscopy in Friedreich's ataxia and ataxia with oculomotor apraxia type 2. Brain research. vol 1358. 2011-01-18. PMID:20713024. |
friedreich's ataxia (frda) and ataxia with oculomotor apraxia type 2 (aoa2) are the two most frequent forms of autosomal recessive cerebellar ataxias. |
2011-01-18 |
2023-08-12 |
Not clear |
| Sascha Vermeer, Alexander Hoischen, Rowdy P P Meijer, Christian Gilissen, Kornelia Neveling, Nienke Wieskamp, Arjan de Brouwer, Michel Koenig, Mathieu Anheim, Mirna Assoum, Nathalie Drouot, Slobodanka Todorovic, Vedrana Milic-Rasic, Hanns Lochmüller, Giovanni Stevanin, Cyril Goizet, Albert David, Alexandra Durr, Alexis Brice, Berry Kremer, Bart P C van de Warrenburg, Mascha M V A P Schijvenaars, Angelien Heister, Michael Kwint, Peer Arts, Jenny van der Wijst, Joris Veltman, Erik-Jan Kamsteeg, Hans Scheffer, Nine Knoer. Targeted next-generation sequencing of a 12.5 Mb homozygous region reveals ANO10 mutations in patients with autosomal-recessive cerebellar ataxia. American journal of human genetics. vol 87. issue 6. 2011-01-18. PMID:21092923. |
autosomal-recessive cerebellar ataxias comprise a clinically and genetically heterogeneous group of neurodegenerative disorders. |
2011-01-18 |
2023-08-12 |
Not clear |
| Ana Paula B Araujo, Maria Emília O B Ribeiro, Ritchelli Ricci, Ricardo J Torquato, Leny Toma, Marimélia A Porcionatt. Glial cells modulate heparan sulfate proteoglycan (HSPG) expression by neuronal precursors during early postnatal cerebellar development. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 28. issue 7. 2011-01-13. PMID:20638466. |
cellular and molecular defects during cerebellar development can lead to severe phenotypes, such as ataxias and tumors. |
2011-01-13 |
2023-08-12 |
Not clear |
| Susan E Tomlinson, S Veronica Tan, Dimitri M Kullmann, Robert C Griggs, David Burke, Michael G Hanna, Hugh Bostoc. Nerve excitability studies characterize Kv1.1 fast potassium channel dysfunction in patients with episodic ataxia type 1. Brain : a journal of neurology. vol 133. issue Pt 12. 2011-01-07. PMID:21106501. |
episodic ataxia type 1 presents with brief episodes of cerebellar dysfunction and persistent neuromyotonia and is associated with an increased incidence of epilepsy. |
2011-01-07 |
2023-08-12 |
Not clear |
| Susanne M Morton, Ya-Weng Tseng, Kathleen M Zackowski, Jaclyn R Daline, Amy J Bastia. Longitudinal tracking of gait and balance impairments in cerebellar disease. Movement disorders : official journal of the Movement Disorder Society. vol 25. issue 12. 2010-12-28. PMID:20544808. |
cerebellar damage typically results in ataxia and can be caused by stroke, tumor, or one of many forms of degenerative disease. |
2010-12-28 |
2023-08-12 |
human |
| Susanne M Morton, Ya-Weng Tseng, Kathleen M Zackowski, Jaclyn R Daline, Amy J Bastia. Longitudinal tracking of gait and balance impairments in cerebellar disease. Movement disorders : official journal of the Movement Disorder Society. vol 25. issue 12. 2010-12-28. PMID:20544808. |
here, we tracked the severity of ataxia, with a particular emphasis on gait and balance dysfunction, in a group of individuals with cerebellar damage using the international cooperative ataxia rating scale (icars) and several instrumented laboratory measures of gait and balance impairments over 1 year. |
2010-12-28 |
2023-08-12 |
human |
| Susanne M Morton, Ya-Weng Tseng, Kathleen M Zackowski, Jaclyn R Daline, Amy J Bastia. Longitudinal tracking of gait and balance impairments in cerebellar disease. Movement disorders : official journal of the Movement Disorder Society. vol 25. issue 12. 2010-12-28. PMID:20544808. |
we found that the icars was able to distinguish between subjects with static lesions and those with degenerative disorders, was sensitive to increases in ataxia severity occurring over 1 year, and correlated well with specific instrumented measures of gait in persons with cerebellar degeneration. |
2010-12-28 |
2023-08-12 |
human |
| Yvonne L Clarkson, Trudi Gillespie, Emma M Perkins, Alastair R Lyndon, Mandy Jackso. Beta-III spectrin mutation L253P associated with spinocerebellar ataxia type 5 interferes with binding to Arp1 and protein trafficking from the Golgi. Human molecular genetics. vol 19. issue 18. 2010-12-23. PMID:20603325. |
here we report the analysis of heterozygous animals, which show no signs of ataxia or cerebellar degeneration up to 2 years of age. |
2010-12-23 |
2023-08-12 |
mouse |
| Julien Jung, Hervé Testard, Elisabeth Tournier-Lasserve, Florence Riant, Anne-Evelyne Vallet, Stéphane Berroir, Emmanuel Broussoll. Phenotypic variability of episodic ataxia type 2 mutations: a family study. European neurology. vol 64. issue 2. 2010-11-24. PMID:20639635. |
episodic ataxia type 2 (ea2) is characterized by paroxysmal bouts of ataxia and progressive cerebellar dysfunction. |
2010-11-24 |
2023-08-12 |
Not clear |
| A GROSSIORD, S GODLEWSK. A new case of cerebellar hereditary ataxia with Parinaud syndrome. Revue neurologique. vol 78. 2010-11-12. PMID:20987791. |
a new case of cerebellar hereditary ataxia with parinaud syndrome. |
2010-11-12 |
2023-08-12 |
Not clear |
| Gülin Oz, Diane Hutter, Ivan Tkác, H Brent Clark, Myron D Gross, Hong Jiang, Lynn E Eberly, Khalaf O Bushara, Christopher M Gome. Neurochemical alterations in spinocerebellar ataxia type 1 and their correlations with clinical status. Movement disorders : official journal of the Movement Disorder Society. vol 25. issue 9. 2010-11-04. PMID:20310029. |
in addition, tnaa, myo-inositol, and glutamate levels in the cerebellar hemispheres and the tnaa and myo-inositol levels in the pons correlated with ataxia scores (scale for the assessment and rating of ataxia, sara). |
2010-11-04 |
2023-08-12 |
human |
| Juan C López-Ramos, Yukiko Tomioka, Masami Morimatsu, Sayo Yamamoto, Kinuyo Ozaki, Etsuro Ono, José M Delgado-Garcí. Motor-coordination-dependent learning, more than others, is impaired in transgenic mice expressing pseudorabies virus immediate-early protein IE180. PloS one. vol 5. issue 8. 2010-11-04. PMID:20711341. |
the cerebellum in transgenic mice expressing pseudorabies virus immediate-early protein ie180 (tgie96) was substantially diminished in size, and its histoarchitecture was severely disorganized, resulting in severe ataxia. |
2010-11-04 |
2023-08-12 |
mouse |