| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christine Mac Donald, Ann Johnson, Dana Cooper, Thomas Malone, James Sorrell, Joshua Shimony, Matthew Parsons, Abraham Snyder, Marcus Raichle, Raymond Fang, Stephen Flaherty, Michael Russell, David L Brod. Cerebellar white matter abnormalities following primary blast injury in US military personnel. PloS one. vol 8. issue 2. 2013-08-05. PMID:23409052. |
however, the clinical effects of these abnormalities cannot be determined with certainty; none of the subjects had ataxia or other detected evidence of cerebellar dysfunction. |
2013-08-05 |
2023-08-12 |
human |
| Xiping Zhan, Werner M Gra. Harmaline attenuates voltage--sensitive Ca(2+) currents in neurons of the inferior olive. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques. vol 15. issue 5. 2013-07-03. PMID:23331904. |
either local or systemic harmaline injection has been reported to increase spiking rate and coherence in the inferior olive and this activation is thought to produce tremor and ataxia through inferior olivary neuron activation of target neurons in the cerebellum, but the cellular mechanism is not yet known. |
2013-07-03 |
2023-08-12 |
Not clear |
| Shuhong Qiao, Sun-Hong Kim, Detlef Heck, Daniel Goldowitz, Mark S LeDoux, Ramin Homayoun. Dab2IP GTPase activating protein regulates dendrite development and synapse number in cerebellum. PloS one. vol 8. issue 1. 2013-07-02. PMID:23326475. |
unlike reeler mice, dab2ip knock-down mice did not exhibit severe ataxia or cerebellar hypoplasia. |
2013-07-02 |
2023-08-12 |
mouse |
| Ashok Aspatwar, Martti E E Tolvanen, Eija Jokitalo, Mataleena Parikka, Csaba Ortutay, Sanna-Kaisa E Harjula, Mika Rämet, Mauno Vihinen, Seppo Parkkil. Abnormal cerebellar development and ataxia in CARP VIII morphant zebrafish. Human molecular genetics. vol 22. issue 3. 2013-07-01. PMID:23087022. |
abnormal cerebellar development and ataxia in carp viii morphant zebrafish. |
2013-07-01 |
2023-08-12 |
mouse |
| M Saeed Dar, Salim Al-Rejai. Tonic modulatory role of mouse cerebellar α- and β-adrenergic receptors in the expression of ethanol-induced ataxia: role of AC-cAMP. Behavioural brain research. vol 241. 2013-07-01. PMID:23246526. |
tonic modulatory role of mouse cerebellar α- and β-adrenergic receptors in the expression of ethanol-induced ataxia: role of ac-camp. |
2013-07-01 |
2023-08-12 |
mouse |
| M Saeed Dar, Salim Al-Rejai. Tonic modulatory role of mouse cerebellar α- and β-adrenergic receptors in the expression of ethanol-induced ataxia: role of AC-cAMP. Behavioural brain research. vol 241. 2013-07-01. PMID:23246526. |
to further study neurochemical basis of ethanol-induced ataxia (eia), we investigated role of cerebellar α and β-adrenergic receptors. |
2013-07-01 |
2023-08-12 |
mouse |
| Hugh J McMillan, Thea Worthylake, Jeremy Schwartzentruber, Chloe C Gottlieb, Sarah E Lawrence, Alex Mackenzie, Chandree L Beaulieu, Petra A W Mooyer, Ronald J A Wanders, Jacek Majewski, Dennis E Bulman, Michael T Geraghty, Sacha Ferdinandusse, Kym M Boycot. Specific combination of compound heterozygous mutations in 17β-hydroxysteroid dehydrogenase type 4 (HSD17B4) defines a new subtype of D-bifunctional protein deficiency. Orphanet journal of rare diseases. vol 7. 2013-06-21. PMID:23181892. |
here we report two brothers (16½ and 14 years old) with dbp deficiency characterized by normal early childhood followed by sensorineural hearing loss, progressive cerebellar and sensory ataxia and subclinical retinitis pigmentosa. |
2013-06-21 |
2023-08-12 |
Not clear |
| Alexandra Lloyd-Smith, Patrizio Jacova, Michael Schulzer, Sian D Space. Early clinical features differentiate cerebellar variant MSA and sporadic ataxia. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 40. issue 2. 2013-06-18. PMID:23419578. |
early clinical features differentiate cerebellar variant msa and sporadic ataxia. |
2013-06-18 |
2023-08-12 |
Not clear |
| R T Chakor, H Bharot. Inherited ataxia with slow saccades. Journal of postgraduate medicine. vol 58. issue 4. 2013-06-17. PMID:23298936. |
ataxia is a symptom of cerebellar dysfunction. |
2013-06-17 |
2023-08-12 |
Not clear |
| Yoshinori Tsurusaki, Yasuko Kobayashi, Masataka Hisano, Shuichi Ito, Hiroshi Doi, Mitsuko Nakashima, Hirotomo Saitsu, Naomichi Matsumoto, Noriko Miyak. The diagnostic utility of exome sequencing in Joubert syndrome and related disorders. Journal of human genetics. vol 58. issue 2. 2013-06-11. PMID:23034536. |
joubert syndrome (js) and related disorders (jsrd) are autosomal recessive and x-linked disorders characterized by hypoplasia of the cerebellar vermis with a characteristic 'molar tooth sign' on brain imaging and accompanying neurological symptoms including episodic hyperpnoea, abnormal eye movements, ataxia and intellectual disability. |
2013-06-11 |
2023-08-12 |
Not clear |
| Mark Walterfang, Larry A Abel, Patricia Desmond, Michael C Fahey, Elizabeth A Bowman, Dennis Velakouli. Cerebellar volume correlates with saccadic gain and ataxia in adult Niemann-Pick type C. Molecular genetics and metabolism. vol 108. issue 1. 2013-06-05. PMID:23266197. |
cerebellar volume correlates with saccadic gain and ataxia in adult niemann-pick type c. cerebellar purkinje cells are known to be highly vulnerable to neuronal pathology in niemann-pick type c (npc), a disease where widespread white matter changes have also been reported. |
2013-06-05 |
2023-08-12 |
Not clear |
| Won Tae Yoon, Jinyoung Youn, Jin Whan Ch. Is cerebral white matter involvement helpful in the diagnosis of dentatorubral-pallidoluysian atrophy? Journal of neurology. vol 259. issue 8. 2013-06-04. PMID:22286658. |
our results of our study indicate that cerebral white matter changes are not rare in drpla and might be helpful for differentiation in ataxia patients with brainstem and cerebellum atrophy. |
2013-06-04 |
2023-08-12 |
Not clear |
| Estela Natacha Brandt Busanello, Ângela Zanatta, Anelise Miotti Tonin, Carolina Maso Viegas, Carmen Regla Vargas, Guilhian Leipnitz, César Augusto João Ribeiro, Moacir Wajne. Marked inhibition of Na+, K(+)- ATPase activity and the respiratory chain by phytanic acid in cerebellum from young rats: possible underlying mechanisms of cerebellar ataxia in Refsum disease. Journal of bioenergetics and biomembranes. vol 45. issue 1-2. 2013-05-23. PMID:23151916. |
therefore, it is presumed that impairment of the electron flow through the respiratory chain and inhibition of na(+), k(+)- atpase that is crucial for synaptic function may be involved in the pathophysiology of the cerebellar abnormalities manifested as ataxia in refsum disease and in other peroxisomal disorders in which brain phyt accumulates. |
2013-05-23 |
2023-08-12 |
rat |
| Kristine M Sikora, LaGina M Nosavanh, Prameela Kantheti, Margit Burmeister, Michael Hortsc. Expression of Caytaxin protein in Cayman Ataxia mouse models correlates with phenotype severity. PloS one. vol 7. issue 11. 2013-05-23. PMID:23226316. |
mutations in atcay/atcay have been identified as causative of cerebellar disorders such as the rare hereditary disease cayman ataxia in humans, generalized dystonia in the dystonic (dt) rat, and marked motor defects in three ataxic mouse lines. |
2013-05-23 |
2023-08-12 |
mouse |
| Brian C Jung, Soo I Choi, Annie X Du, Jennifer L Cuzzocreo, Zhuo Z Geng, Howard S Ying, Susan L Perlman, Arthur W Toga, Jerry L Prince, Sarah H Yin. Principal component analysis of cerebellar shape on MRI separates SCA types 2 and 6 into two archetypal modes of degeneration. Cerebellum (London, England). vol 11. issue 4. 2013-04-24. PMID:22258915. |
in comparison, archetype #2 was comprised of disease groups with pure cerebellar atrophy (episodic ataxia type 2 (n=1), idiopathic late-onset cerebellar ataxias (n=3), and sca6). |
2013-04-24 |
2023-08-12 |
human |
| Carmela Conte, Mariano Serrao, Carlo Casali, Alberto Ranavolo, Mari Silvia, Francesco Draicchio, Roberto Di Fabio, Stefano Monami, Luca Padua, Sergio Iavicoli, Giorgio Sandrini, Francesco Pierell. Planned gait termination in cerebellar ataxias. Cerebellum (London, England). vol 11. issue 4. 2013-04-24. PMID:22274811. |
planned gait termination in cerebellar ataxias. |
2013-04-24 |
2023-08-12 |
human |
| Pedro Braga-Neto, Lívia Almeida Dutra, José Luiz Pedroso, André C Felício, Helena Alessi, Ruth F Santos-Galduroz, Paulo Henrique F Bertolucci, Mário Luiz V Castiglioni, Rodrigo Affonseca Bressan, Griselda Esther Jara de Garrido, Orlando Graziani Povoas Barsottini, Andrea Jackowsk. Cognitive deficits in Machado-Joseph disease correlate with hypoperfusion of visual system areas. Cerebellum (London, England). vol 11. issue 4. 2013-04-24. PMID:22307858. |
the severity of cerebellar symptoms was measured using the international cooperative ataxia rating scale and the scale for the assessment and rating of ataxia. |
2013-04-24 |
2023-08-12 |
human |
| C Deluca, G Moretto, A Di Matteo, M Cappellari, A Fiaschi, M Tinazz. Hemi- and monoataxia in cerebellar hemispheres and peduncles stroke lesions: topographical correlations. Cerebellum (London, England). vol 11. issue 4. 2013-04-24. PMID:22351351. |
limb ataxia of sudden onset is due to a vascular lesion in either the cerebellum or the brainstem (posterior circulation, pc, territory). |
2013-04-24 |
2023-08-12 |
Not clear |
| Fadi A Issa, Allan F Mock, Alvaro Sagasti, Diane M Papazia. Spinocerebellar ataxia type 13 mutation that is associated with disease onset in infancy disrupts axonal pathfinding during neuronal development. Disease models & mechanisms. vol 5. issue 6. 2013-04-19. PMID:22736459. |
sca13 exists in two forms: infant onset is characterized by severe cerebellar atrophy, persistent motor deficits and intellectual disability, whereas adult onset is characterized by progressive ataxia and progressive cerebellar degeneration. |
2013-04-19 |
2023-08-12 |
zebrafish |
| Christina Votsi, Eleni Zamba-Papanicolaou, Anthi Georghiou, Theodoros Kyriakides, Savvas Papacostas, Kleopas A Kleopa, Marios Pantzaris, Kyproula Christodoulo. Investigation of SCA10 in the Cypriot population: further exclusion of SCA dynamic repeat mutations. Journal of the neurological sciences. vol 323. issue 1-2. 2013-04-18. PMID:23026538. |
autosomal dominant cerebellar ataxias (adcas) encompass a heterogeneous group of rare diseases that affect the cerebellum and its connections. |
2013-04-18 |
2023-08-12 |
Not clear |