| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hsin Fen Chien, Marise Bueno Zonta, Janini Chen, Giovana Diaferia, Celiana Figueiredo Viana, Hélio Afonso Ghizoni Teive, José Luiz Pedroso, Orlando Graziani Povoas Barsottin. Rehabilitation in patients with cerebellar ataxias. Arquivos de neuro-psiquiatria. 2022-03-03. PMID:35239817. |
usually, the genetic and neurodegenerative forms of cerebellar ataxias present a progressive and inevitable worsening of the clinical picture so that rehabilitation treatment is fundamental. |
2022-03-03 |
2023-08-13 |
Not clear |
| Xiang Chen, Tong Chen, Chen Dong, Huiyao Chen, Xinran Dong, Lin Yang, Liyuan Hu, Huijun Wang, Bingbing Wu, Ye Yao, Yu Xiong, Man Xiong, Yifeng Lin, Wenhao Zho. Deletion of CHD8 in cerebellar granule neuron progenitors leads to severe cerebellar hypoplasia, ataxia and psychiatric behavior in mice. Journal of genetics and genomics = Yi chuan xue bao. 2022-03-01. PMID:35231638. |
deletion of chd8 in cerebellar granule neuron progenitors leads to severe cerebellar hypoplasia, ataxia and psychiatric behavior in mice. |
2022-03-01 |
2023-08-13 |
mouse |
| H Brent Clar. The Neuropathology of Autoimmune Ataxias. Brain sciences. vol 12. issue 2. 2022-02-25. PMID:35204019. |
such factors as rapid rate of clinical progression, presence of known autoantibodies or the presence of a malignant neoplasm or other autoimmune disease processes need to be considered, particularly in cases where inflammatory changes are minimal or absent and the pathology is largely confined to the cerebellum and its connections, where the disease can mimic hereditary or other sporadic ataxias. |
2022-02-25 |
2023-08-13 |
Not clear |
| Mario Mascalch. MRI CNS Atrophy Pattern and the Etiologies of Progressive Ataxias. Tomography (Ann Arbor, Mich.). vol 8. issue 1. 2022-02-24. PMID:35202200. |
mri shows the three archetypal patterns of cns volume loss underlying progressive ataxias in vivo, namely spinal atrophy (sa), cortical cerebellar atrophy (cca) and olivopontocerebellar atrophy (opca). |
2022-02-24 |
2023-08-13 |
Not clear |
| Ian H Harding, Phillip G D War. Brain susceptibility imaging provides valuable Brain communications. vol 4. issue 1. 2022-02-18. PMID:35178517. |
brain susceptibility imaging provides valuable this scientific commentary relates to: 'quantitative susceptibility mapping reveals alterations of dentate nuclei in common types of degenerative cerebellar ataxias' by deistung |
2022-02-18 |
2023-08-13 |
Not clear |
| Izumi Aida, Tetsuo Ozawa, Kentaro Ohta, Hidehiko Fujinaka, Kiyoe Goto, Takashi Nakajim. Autosomal Recessive Spinocerebellar Ataxia Type 10: A Report of a New Case in Japan. Internal medicine (Tokyo, Japan). 2022-02-03. PMID:35110481. |
this case presented with adult-onset slowly progressive spastic ataxia with cerebellar atrophy and mild cognitive decline. |
2022-02-03 |
2023-08-13 |
Not clear |
| Benjamin Roeben, Eva Bültmann, Claudia Stendel, Matthis Synofzi. Cerebellar Bottom of Fissure Hyperintensities in MT-ATP6-associated Ataxia. Annals of neurology. 2022-01-30. PMID:35094430. |
cerebellar bottom of fissure hyperintensities in mt-atp6-associated ataxia. |
2022-01-30 |
2023-08-13 |
Not clear |
| Hiroshi Mitoma, Mario Mant. Advances in the Pathogenesis of Auto-antibody-Induced Cerebellar Synaptopathies. Cerebellum (London, England). 2022-01-22. PMID:35064896. |
the presence of auto-antibodies that target synaptic machinery proteins was documented recently in immune-mediated cerebellar ataxias. |
2022-01-22 |
2023-08-13 |
Not clear |
| Natale Maiorana, Matteo Guidetti, Michelangelo Dini, Alberto Priori, Roberta Ferrucc. Cerebellar tDCS as Therapy for Cerebellar Ataxias. Cerebellum (London, England). 2022-01-21. PMID:35060077. |
cerebellar tdcs as therapy for cerebellar ataxias. |
2022-01-21 |
2023-08-13 |
Not clear |
| Natale Maiorana, Matteo Guidetti, Michelangelo Dini, Alberto Priori, Roberta Ferrucc. Cerebellar tDCS as Therapy for Cerebellar Ataxias. Cerebellum (London, England). 2022-01-21. PMID:35060077. |
cerebellar ataxias (cas) represent the prototypical clinical manifestation of cerebellar alterations, but other movement disorders, such as parkinson's disease, essential tremor, and dystonia have also been associated with alterations of networks which include the cerebellum, or of the cerebellum itself. |
2022-01-21 |
2023-08-13 |
Not clear |
| Sergio Muñiz-Castrillo, Alberto Vogrig, Nicolás Lundahl Ciano-Petersen, Macarena Villagrán-García, Bastien Joubert, Jérôme Honnora. Novelties in Autoimmune and Paraneoplastic Cerebellar Ataxias: Twenty Years of Progresses. Cerebellum (London, England). 2022-01-12. PMID:35020135. |
novelties in autoimmune and paraneoplastic cerebellar ataxias: twenty years of progresses. |
2022-01-12 |
2023-08-13 |
Not clear |
| Sergio Muñiz-Castrillo, Alberto Vogrig, Nicolás Lundahl Ciano-Petersen, Macarena Villagrán-García, Bastien Joubert, Jérôme Honnora. Novelties in Autoimmune and Paraneoplastic Cerebellar Ataxias: Twenty Years of Progresses. Cerebellum (London, England). 2022-01-12. PMID:35020135. |
major advances in our knowledge concerning autoimmune and paraneoplastic cerebellar ataxias have occurred in the last 20 years. |
2022-01-12 |
2023-08-13 |
Not clear |
| Sergio Muñiz-Castrillo, Alberto Vogrig, Nicolás Lundahl Ciano-Petersen, Macarena Villagrán-García, Bastien Joubert, Jérôme Honnora. Novelties in Autoimmune and Paraneoplastic Cerebellar Ataxias: Twenty Years of Progresses. Cerebellum (London, England). 2022-01-12. PMID:35020135. |
moreover, important advances in our understanding of the pathogenesis of cerebellar ataxias include the description of antibody effects, especially those targeting cell-surface antigens, and first attempts to isolate antigen-specific t-cells. |
2022-01-12 |
2023-08-13 |
Not clear |
| Sergio Muñiz-Castrillo, Alberto Vogrig, Nicolás Lundahl Ciano-Petersen, Macarena Villagrán-García, Bastien Joubert, Jérôme Honnora. Novelties in Autoimmune and Paraneoplastic Cerebellar Ataxias: Twenty Years of Progresses. Cerebellum (London, England). 2022-01-12. PMID:35020135. |
herein, we review the principal novelties of the last 20 years regarding autoimmune and paraneoplastic cerebellar ataxias. |
2022-01-12 |
2023-08-13 |
Not clear |
| Hiroshi Mitoma, Jerome Honnorat, Kazuhiko Yamaguchi, Mario Mant. Cerebellar long-term depression and auto-immune target of auto-antibodies: the concept of LTDpathies. Molecular biomedicine. vol 2. issue 1. 2022-01-10. PMID:35006439. |
in immune-mediated cerebellar ataxias (imcas), various synaptic proteins, such as gad65, voltage-gated ca channel (vgcc), metabotropic glutamate receptor type 1 (mglur1), and glutamate receptor delta (glur delta) are auto-immune targets. |
2022-01-10 |
2023-08-13 |
Not clear |
| Hiroshi Mitoma, Jerome Honnorat, Kazuhiko Yamaguchi, Mario Mant. Cerebellar long-term depression and auto-immune target of auto-antibodies: the concept of LTDpathies. Molecular biomedicine. vol 2. issue 1. 2022-01-10. PMID:35006439. |
we suggest that anti-vgcc, anti-mglur1, and anti-glur delta abs-associated cerebellar ataxias share one common pathophysiological mechanism: a deregulation in pf-pc ltd, which results in impairment of restoration or maintenance of the internal model and triggers cerebellar ataxias. |
2022-01-10 |
2023-08-13 |
Not clear |
| Filip Tichane. Psychiatric-Like Impairments in Mouse Models of Spinocerebellar Ataxias. Cerebellum (London, England). 2022-01-09. PMID:35000108. |
in sca1 mice with complex neuropathology, some of the psychiatric-like impairments are present even before marked cerebellar degeneration and ataxia and correlate with hippocampal atrophy. |
2022-01-09 |
2023-08-13 |
mouse |
| Filip Tichane. Psychiatric-Like Impairments in Mouse Models of Spinocerebellar Ataxias. Cerebellum (London, England). 2022-01-09. PMID:35000108. |
similarly, complete or partial deletion of the implicated gene (atxn1) leads to cognitive dysfunction and anxiety-like behavior, respectively, without apparent ataxia and cerebellar degeneration. |
2022-01-09 |
2023-08-13 |
mouse |
| Reiko Ashida, Peter Walsh, Jonathan C W Brooks, Nadia L Cerminara, Richard Apps, Richard J Edward. Sensory and motor electrophysiological mapping of the cerebellum in humans. Scientific reports. vol 12. issue 1. 2022-01-08. PMID:34997137. |
cerebellar damage during posterior fossa surgery in children can lead to ataxia and risk of cerebellar mutism syndrome. |
2022-01-08 |
2023-08-13 |
human |
| Polina A Egorova, Ilya B Bezprozvann. Electrophysiological Studies Support Utility of Positive Modulators of SK Channels for the Treatment of Spinocerebellar Ataxia Type 2. Cerebellum (London, England). 2022-01-03. PMID:34978024. |
the abnormal intrinsic pacemaking was reported in mouse models of episodic ataxia type 2 (ea2), sca1, sca2, sca3, sca6, huntington's disease (hd), and in some other murine models of the disorders associated with the cerebellar degeneration. |
2022-01-03 |
2023-08-13 |
mouse |