Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Heather O'Leary, Lauren Vanderlinden, Lara Southard, Anna Castano, Laura M Saba, Tim A Benk. Transcriptome analysis of rat dorsal hippocampal CA1 after an early life seizure induced by kainic acid. Epilepsy research. vol 161. 2021-08-18. PMID:32062370. |
our previous work also demonstrated increased expression of ca1 hippocampal long-term potentiation (ltp) and reduced desensitization of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type ionotropic glutamate receptors (ampa-r) one week following a kainic acid induced seizure (ka-els). |
2021-08-18 |
2023-08-13 |
rat |
Ying-Chou Wang, Wei-Che Chiu, Cai-N Cheng, Chiang Lee, Andrew Chih Wei Huan. Examination of neuroinflammatory cytokine interleukin-1 beta expression in the medial prefrontal cortex, amygdala, and hippocampus for the paradoxical effects of reward and aversion induced by morphine. Neuroscience letters. vol 760. 2021-08-17. PMID:34153368. |
however, no research examined whether neuroinflammatory changes in the mpfc [including cingulate cortex area 1 (cg1); prelimbic cortex (prl); infralimbic cortex (il)], basolateral amygdala, and hippocampus [e.g., ca1, ca2, ca3, and dentate gyrus (dg)] after morphine-induced reward in conditioned place preference (cpp) and aversion in conditioned taste aversion (cta). |
2021-08-17 |
2023-08-13 |
Not clear |
Ying-Chou Wang, Wei-Che Chiu, Cai-N Cheng, Chiang Lee, Andrew Chih Wei Huan. Examination of neuroinflammatory cytokine interleukin-1 beta expression in the medial prefrontal cortex, amygdala, and hippocampus for the paradoxical effects of reward and aversion induced by morphine. Neuroscience letters. vol 760. 2021-08-17. PMID:34153368. |
the prl and il of the mpfc, the bla of the amygdala, the ca1, ca2, ca3, and dg of the hippocampus but not the cg1 presented hyperactive il-1β expression in response to morphine's aversion and reward. |
2021-08-17 |
2023-08-13 |
Not clear |
Nikhil Dave, Austin S Vural, Ignazio S Piras, Wendy Winslow, Likith Surendra, Joanna K Winstone, Thomas G Beach, Matthew J Huentelman, Ramon Velazque. Identification of retinoblastoma binding protein 7 (Rbbp7) as a mediator against tau acetylation and subsequent neuronal loss in Alzheimer's disease and related tauopathies. Acta neuropathologica. vol 142. issue 2. 2021-08-16. PMID:33978814. |
in vivo, hippocampal rbbp7 overexpression rescued neuronal death in the ca1 of ps19 mice. |
2021-08-16 |
2023-08-13 |
mouse |
I V Kastyro, I V Reshetov, G V Khamidulin, S S Shilin, V I Torshin, M G Kostyaeva, V I Popadyuk, T Y Yunusov, P E Shmaevsky, K P Shalamov, A D Kupryakova, E S Doroginskaya, A D Sedelnikov. Influence of Surgical Trauma in the Nasal Cavity on the Expression of p53 Protein in the Hippocampus of Rats. Doklady. Biochemistry and biophysics. vol 497. issue 1. 2021-08-13. PMID:33895923. |
a quantitative assessment of the apoptosis of neurons in the pyramidal layer of the hippocampus in the subfields ca1, ca2, ca3, and dentate gyrus (dg) on days 2, 4, and 6 after surgery was carried out. |
2021-08-13 |
2023-08-13 |
rat |
Victor Rodrigues Santos, Igor Santana Melo, Amanda Larissa Dias Pacheco, Olagide Wagner de Castr. Life and death in the hippocampus: What's bad? Epilepsy & behavior : E&B. vol 121. issue Pt B. 2021-08-11. PMID:31759972. |
classically, neurodegeneration affects sensitive areas of the hippocampus, such as dentate gyrus (dg) hilus, as well as specific fields of the ammon's horn, ca3, and ca1. |
2021-08-11 |
2023-08-13 |
Not clear |
Satoshi Iwasaki, Yuji Ikegay. Contextual Fear Memory Retrieval Is Vulnerable to Hippocampal Noise. Cerebral cortex (New York, N.Y. : 1991). vol 31. issue 2. 2021-08-11. PMID:32935839. |
these results indicate that hippocampal memory retrieval requires strictly regulated activation of a specific neuron ensemble and is easily disrupted by the introduction of noisy ca1 activity, suggesting that reactivating memory engram cells as well as silencing memory-irrelevant neurons are both crucial for memory retrieval. |
2021-08-11 |
2023-08-13 |
Not clear |
Pierre Lecouflet, Candice M Roux, Brigitte Potier, Marianne Leger, Elie Brunet, Jean-Marie Billard, Pascale Schumann-Bard, Thomas Frere. Interplay between 5-HT4 Receptors and GABAergic System within CA1 Hippocampal Synaptic Plasticity. Cerebral cortex (New York, N.Y. : 1991). vol 31. issue 1. 2021-08-11. PMID:32935845. |
interplay between 5-ht4 receptors and gabaergic system within ca1 hippocampal synaptic plasticity. |
2021-08-11 |
2023-08-13 |
Not clear |
Jie Zhang, Zhewen Chen, Huaixi Yu, Yanwen Lu, Weinan Yu, Mingyong Miao, Hanping Sh. Anti-aging effects of a functional food via the action of gut microbiota and metabolites in aging mice. Aging. vol 13. issue 13. 2021-08-04. PMID:33878733. |
the ca1 hippocampal region in ws-fed aged mice showed fewer shriveled neurons and increased neuronal layers compared to that of the sd group. |
2021-08-04 |
2023-08-13 |
mouse |
Eric W Buss, Nicola J Corbett, Joshua G Roberts, Natividad Ybarra, Timothy F Musial, Dina Simkin, Elizabeth Molina-Campos, Kwang-Jin Oh, Lauren L Nielsen, Gelique D Ayala, Sheila A Mullen, Anise K Farooqi, Gary X D'Souza, Corinne L Hill, Linda A Bean, Annalise E Rogalsky, Matthew L Russo, Dani M Curlik, Marci D Antion, Craig Weiss, Dane M Chetkovich, M Matthew Oh, John F Disterhoft, Daniel A Nicholso. Cognitive aging is associated with redistribution of synaptic weights in the hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 118. issue 8. 2021-08-03. PMID:33593893. |
here we show that the synaptic architecture of hippocampal regions ca1 and ca3 is maintained in a young adult-like state in aged rats that performed comparably to their young adult counterparts in both trace eyeblink conditioning and morris water maze learning. |
2021-08-03 |
2023-08-13 |
rat |
Surya P Aryal, Xu Fu, Joree N Sandin, Khaga R Neupane, Jourdan E Lakes, Martha E Grady, Christopher I Richard. Nicotine induces morphological and functional changes in astrocytes via nicotinic receptor activity. Glia. vol 69. issue 8. 2021-08-02. PMID:33851731. |
we find that nicotine induces a change in the volume of astrocytes in the prefrontal cortex, ca1 of the hippocampus, and the substantia nigra. |
2021-08-02 |
2023-08-13 |
mouse |
Ivana Kiroski, Yulan Jiang, Cezar Gavrilovici, Fan Gao, Sukyoung Lee, Morris H Scantlebury, Milene Vandal, Sang Ki Park, Li-Huei Tsai, G Campbell Teskey, Jong M Rho, Minh Dang Nguye. Reelin Improves Cognition and Extends the Lifespan of Mutant Ndel1 Mice with Postnatal CA1 Hippocampus Deterioration. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 9. 2021-07-31. PMID:32328622. |
reelin improves cognition and extends the lifespan of mutant ndel1 mice with postnatal ca1 hippocampus deterioration. |
2021-07-31 |
2023-08-13 |
mouse |
Ivana Kiroski, Yulan Jiang, Cezar Gavrilovici, Fan Gao, Sukyoung Lee, Morris H Scantlebury, Milene Vandal, Sang Ki Park, Li-Huei Tsai, G Campbell Teskey, Jong M Rho, Minh Dang Nguye. Reelin Improves Cognition and Extends the Lifespan of Mutant Ndel1 Mice with Postnatal CA1 Hippocampus Deterioration. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 9. 2021-07-31. PMID:32328622. |
ndel1 cko mice exhibit fragmented microtubules in ca1 pyramidal neurons, profound deterioration of the ca1 hippocampus and a shortened lifespan (~10 weeks). |
2021-07-31 |
2023-08-13 |
mouse |
Laleh Rezaee, Amir-Mohammad Alizadeh, Abbas Haghparas. Role of hippocampal dopamine receptors in the antinociceptive responses induced by chemical stimulation of the lateral hypothalamus in animal model of acute pain. Brain research. vol 1734. 2021-07-28. PMID:32135149. |
previous studies have shown that the role of ca1 region of the hippocampus in antinociception induced by stimulation of the lateral hypothalamus (lh) through the dopaminergic system in tonic pain. |
2021-07-28 |
2023-08-13 |
rat |
Poornima D E Weerasinghe-Mudiyanselage, Mary Jasmin Ang, Mai Wada, Sung-Ho Kim, Taekyun Shin, Miyoung Yang, Changjong Moo. Acute MPTP Treatment Impairs Dendritic Spine Density in the Mouse Hippocampus. Brain sciences. vol 11. issue 7. 2021-07-27. PMID:34201837. |
golgi staining showed that acute mptp treatment significantly reduced the spine density of neuronal dendrites in the cornu ammonis 1 (ca1) apical/basal and dentate gyrus (dg) subregions of the mouse hippocampus at 8 and 16 days after treatment, although it did not affect dendritic complexity (e.g., number of crossing dendrites, total dendritic length, and branch points per neuron) in both ca1 and dg subregions at all time points after treatment. |
2021-07-27 |
2023-08-13 |
mouse |
Yulia K Komleva, Olga L Lopatina, Iana V Gorina, Anton N Shuvaev, Anatoly Chernykh, Ilia V Potapenko, Alla B Salmin. NLRP3 deficiency-induced hippocampal dysfunction and anxiety-like behavior in mice. Brain research. vol 1752. 2021-07-22. PMID:33358726. |
these include the following: anxious behavior and deterioration in learning and memory of fear conditioning; impairment of adult neurogenesis; reduction and altered morphology of astrocytes in the brain; hyperexcitability in basolateral amygdala (bla); impaired activation in axons of pyramidal cells of ca1 hippocampal zone in nlrp3 ko mice particularly via the schaffer collateral pathway; and impaired synaptic transduction in pyramidal cells mediated by an embarrassment of neurotransmitter release from presynaptic site in ca3 hippocampal zone. |
2021-07-22 |
2023-08-13 |
mouse |
Duk-Shin Lee, Ji-Eun Ki. Regional specific activations of ERK1/2 and CDK5 differently regulate astroglial responses to ER stress in the rat hippocampus following status epilepticus. Brain research. vol 1753. 2021-07-22. PMID:33422538. |
in the present study, tunicamycin-induced er stress resulted in reactive astrogliosis-like events showing astroglial hypertrophy with the elevated extracellular signal-activated protein kinase 1/2 (erk1/2) and cyclin-dependent kinase 5 (cdk5) phosphorylations in the ca1 region of the rat hippocampus. |
2021-07-22 |
2023-08-13 |
rat |
Michael Zhang, Haley F Spencer, Rina Y Berman, Kennett D Radford, Kwang H Cho. Effects of subanesthetic intravenous ketamine infusion on neuroplasticity-related proteins in male and female Sprague-Dawley rats. IBRO neuroscience reports. vol 11. 2021-07-22. PMID:34286313. |
two hours after the infusion, brain tissue was dissected to obtain the medial prefrontal cortex (mpfc), hippocampus including the ca1, ca3, and dentate gyrus, and amygdala followed by western blot analyses of a transcription factor (c-fos), brain-derived neurotrophic factor (bdnf), and phosphorylated extracellular signal-regulated kinase (perk). |
2021-07-22 |
2023-08-13 |
rat |
Mehrdad Jahanshahi, Masoumeh Khalili, Asra Margedar. Naringin Chelates Excessive Iron and Prevents the Formation of Amyloid-Beta Plaques in the Hippocampus of Iron-Overloaded Mice. Frontiers in pharmacology. vol 12. 2021-07-20. PMID:34276359. |
in addition, aβ plaque numbers in ca1, ca3, and dg areas of the hippocampus decreased significantly following treatment with 30 or 60 mg/kg/day naringin. |
2021-07-20 |
2023-08-13 |
mouse |
Bo Jiang, Wenhui Yang, Zhilong Xiu, Liuwei Zhang, Xinxiu Ren, Lijun Wang, Lei Chen, Tetsuya Asakaw. An in vivo explorative study to observe the protective effects of Puerariae flos extract on chronic ethanol exposure and withdrawal male mice. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 137. 2021-07-19. PMID:33524786. |
the changes of neuropsychological behaviors; hippocampal bdnf expression and ca1 neuronal density; and plasma corticotropin-releasing hormone (crh), acth, and cort levels were observed. |
2021-07-19 |
2023-08-13 |
mouse |