Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
A Mitani, Y Andou, K Kataok. Selective vulnerability of hippocampal CA1 neurons cannot be explained in terms of an increase in glutamate concentration during ischemia in the gerbil: brain microdialysis study. Neuroscience. vol 48. issue 2. 1992-07-16. PMID:1351267. |
in the present study, we measured the levels of released glutamate during ischemia in field ca1 and field ca3, separately, and evaluated whether there are subregional differences in the concentration of released glutamate which could be a satisfactory explanation for the selective vulnerability of hippocampal neurons to ischemia. |
1992-07-16 |
2023-08-11 |
Not clear |
M Nakamura, M Araki, K Oguro, T Masuzaw. Differential distribution of 68 Kd and 200 Kd neurofilament proteins in the gerbil hippocampus and their early distributional changes following transient forebrain ischemia. Experimental brain research. vol 89. issue 1. 1992-07-16. PMID:1601102. |
in the normal hippocampus, nf68-like immunoreactivity (nf68-li) was densely distributed in nerve processes in ca2, ca3 and the hilus of the dentate gyrus but was less intense in ca1. |
1992-07-16 |
2023-08-11 |
Not clear |
S O Landgre. Pregnanolone (3 alpha-hydroxy-5 alpha-pregnane-20-one), a progesterone metabolite, facilitates inhibition of synaptic transmission in the Schäffer collateral pathway of the guinea pig hippocampus in vitro. Epilepsy research. vol 10. issue 2-3. 1992-07-15. PMID:1667909. |
pregnanolone (3 alpha-hydroxy-5 alpha-pregnane-20-one, a metabolite of progesterone) caused a significant depression of the amplitude of the population spike evoked in stratum pyramidale in ca1 of the guinea pig hippocampus in vitro. |
1992-07-15 |
2023-08-11 |
Not clear |
O V Garaschuk, Y N Kovalchuk, O A Krishta. Trans-ACPD selectively inhibits excitability of hippocampal CA1 neurones. European journal of pharmacology. vol 212. issue 2-3. 1992-07-13. PMID:1318217. |
the selective agonist of metabotropic glutamate receptors, t-acpd (trans-1-aminocyclopentyl-1,3-dicarboxylic acid) (100-250 microm), reversibly inhibited extracellularly recorded epsp (excitatory postsynaptic potentials) in the ca1 layer of rat hippocampus. |
1992-07-13 |
2023-08-11 |
rat |
H Markram, M Sega. The inositol 1,4,5-trisphosphate pathway mediates cholinergic potentiation of rat hippocampal neuronal responses to NMDA. The Journal of physiology. vol 447. 1992-07-02. PMID:1593457. |
the cellular mechanism by which acetylcholine (ach) potentiates neuronal responses to n-methyl-d-aspartate (nmda) was investigated in ca1 neurones of hippocampal slices using current- and voltage-clamp techniques. |
1992-07-02 |
2023-08-11 |
rat |
L Kruger, C Bendotti, R Rivolta, R Samani. GAP-43 mRNA localization in the rat hippocampus CA3 field. Brain research. Molecular brain research. vol 13. issue 3. 1992-06-29. PMID:1317499. |
additional hippocampal regions of moderate expression include the tenia tecta and the subicular and entorhinal fields, but ca1 and ca2 are strikingly lower in signal. |
1992-06-29 |
2023-08-11 |
rat |
N Ropert, N Gu. Serotonin facilitates GABAergic transmission in the CA1 region of rat hippocampus in vitro. The Journal of physiology. vol 441. 1992-06-26. PMID:1687746. |
serotonin facilitates gabaergic transmission in the ca1 region of rat hippocampus in vitro. |
1992-06-26 |
2023-08-11 |
rat |
C Moncada, B Arvin, E Le Peillet, B S Meldru. Non-NMDA antagonists protect against kainate more than AMPA toxicity in the rat hippocampus. Neuroscience letters. vol 133. issue 2. 1992-06-26. PMID:1816508. |
single focal injection of the excitatory amino acids (eaas) kainic acid (ka, 1.1 nmol/microliters) and (s)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (s)-ampa, 6 nmol/microliters) into rat dorsal hippocampus resulted in widespread neurodegeneration with 90-100% loss of hippocampal pyramidal cells in ca1, ca2, ca3 and ca4 subfields, and 50-70% loss of dentate granule (dg) cells. |
1992-06-26 |
2023-08-11 |
rat |
C Moncada, B Arvin, E Le Peillet, B S Meldru. Non-NMDA antagonists protect against kainate more than AMPA toxicity in the rat hippocampus. Neuroscience letters. vol 133. issue 2. 1992-06-26. PMID:1816508. |
protected against (s)-ampa toxicity in the dg cells but no protection was observed against (s)-ampa toxicity in hippocampal subfields (ca1, ca2 and ca4). |
1992-06-26 |
2023-08-11 |
rat |
D M Kullmann, R A Nicol. Long-term potentiation is associated with increases in quantal content and quantal amplitude. Nature. vol 357. issue 6375. 1992-06-19. PMID:1317014. |
long-term potentiation (ltp) of synaptic transmission in ca1 neurons of the hippocampus, elicited by the conjunction of presynaptic firing and postsynaptic depolarization, is an important model of plasticity, which may underlie memory storage. |
1992-06-19 |
2023-08-11 |
Not clear |
E E Krieckhaus, J W Donahoe, M A Morga. Paranoid schizophrenia may be caused by dopamine hyperactivity of CA1 hippocampus. Biological psychiatry. vol 31. issue 6. 1992-06-18. PMID:1349833. |
paranoid schizophrenia may be caused by dopamine hyperactivity of ca1 hippocampus. |
1992-06-18 |
2023-08-11 |
Not clear |
S G Bec. 5-Hydroxytryptamine increases excitability of CA1 hippocampal pyramidal cells. Synapse (New York, N.Y.). vol 10. issue 4. 1992-06-18. PMID:1585262. |
in the presence of spiperone to block the 5-ht1a-mediated inhibition of pyramidal cell activity, 5-hydroxytryptamine (serotonin, 5-ht) produces a rapid transient increase in amplitude of the extracellularly recorded population spike from area ca1 of the hippocampus. |
1992-06-18 |
2023-08-11 |
rat |
S G Bec. 5-Hydroxytryptamine increases excitability of CA1 hippocampal pyramidal cells. Synapse (New York, N.Y.). vol 10. issue 4. 1992-06-18. PMID:1585262. |
intracellular recording techniques in area ca1 of rat hippocampal slices were used to identify the ionic mechanism and to characterize the 5-ht receptor mediating this excitatory response to 5-ht. |
1992-06-18 |
2023-08-11 |
rat |
V I Malakhova, O V Godukhin, M N Kondrashov. [Influence of succinate on the effectiveness of glutamatergic synaptic transmission in surviving slices of rat hippocampus]. Neirofiziologiia = Neurophysiology. vol 24. issue 1. 1992-06-16. PMID:1350064. |
it is shown that administration of sodium succinate (50 mg/kg i. p.) to rats 30 min prior to decapitation stabilizes glutamate transmission in field ca1 of the rat hippocampal slices and increases duration of its potentiation state. |
1992-06-16 |
2023-08-11 |
rat |
S M Dudek, M F Bea. Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade. Proceedings of the National Academy of Sciences of the United States of America. vol 89. issue 10. 1992-06-16. PMID:1350090. |
homosynaptic long-term depression in area ca1 of hippocampus and effects of n-methyl-d-aspartate receptor blockade. |
1992-06-16 |
2023-08-11 |
rat |
R A Palovcik, S A Reid, J C Principe, A Albuquerqu. 3-D computer animation of electrophysiological responses. Journal of neuroscience methods. vol 41. issue 1. 1992-06-09. PMID:1578897. |
in rat hippocampal slice, stimulation of the schaffer collateral-commissural pathway in stratum radiatum (sr) near ca2 elicited evoked extracellular responses along the length of ca1 from the alveus to stratum lacunosum moleculare (slm). |
1992-06-09 |
2023-08-11 |
human |
N McGuinness, R Anwyl, M Rowa. The effects of trans-ACPD on long-term potentiation in the rat hippocampal slice. Neuroreport. vol 2. issue 11. 1992-06-03. PMID:1667272. |
trans-acpd, a metabotropic glutamate receptor agonist, enhanced both the short-term potentiation (stp) at 1 and 5 min, and long-term potentiation (ltp) at 20 min, following tetanic stimulation, of the population, excitatory postsynaptic potential (epsp) recorded from ca1 of the rat hippocampal slice. |
1992-06-03 |
2023-08-11 |
rat |
P Popoli, A Pezzola, S Sagratella, Y C Zeng, A Scotti de Caroli. Cromakalim (BRL 34915) counteracts the epileptiform activity elicited by diltiazem and verapamil in rats. British journal of pharmacology. vol 104. issue 4. 1992-06-03. PMID:1667291. |
in hippocampal slices, verapamil (1.5-2.0 mm) produced, within 30-60 min of perfusion, a ca1 epileptiform bursting in 80% of the experiments. |
1992-06-03 |
2023-08-11 |
rat |
S D Mendelson, B S McEwe. Autoradiographic analyses of the effects of adrenalectomy and corticosterone on 5-HT1A and 5-HT1B receptors in the dorsal hippocampus and cortex of the rat. Neuroendocrinology. vol 55. issue 4. 1992-05-21. PMID:1533016. |
no treatment affected binding at 5-ht1a receptors in the ca1 region of the hippocampus or in the cortex. |
1992-05-21 |
2023-08-11 |
rat |
M Morioka, K Fukunaga, S Yasugawa, S Nagahiro, Y Ushio, E Miyamot. Regional and temporal alterations in Ca2+/calmodulin-dependent protein kinase II and calcineurin in the hippocampus of rat brain after transient forebrain ischemia. Journal of neurochemistry. vol 58. issue 5. 1992-05-11. PMID:1313854. |
immunoreactivity and enzyme activity of cam kinase ii decreased in regions ca1 and ca3, and in the dentate gyrus, of the hippocampus early (6-12 h) after ischemia, but the decrease in immunoreactivity gradually recovered over time, except in the ca1 region. |
1992-05-11 |
2023-08-11 |
rat |