| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mohammed M Nakhal, Lidya K Yassin, Shaikha Al Houqani, Ayishal B Mydeen, Marwa F Ibrahim, Safa Shehab, Mohammed Z Allouh, Mohammad I K Hama. Early-Life Stress Caused by Maternal Deprivation Impacts Dendritic Morphology of Adult Male Mouse Neocortical Interneurons. International journal of molecular sciences. vol 26. issue 5. 2025-03-13. PMID:40076536. |
to ascertain whether els induces alterations in the morphology of gabaergic inhibitory interneurons in layers ii/iii of the medial entorhinal cortex (mec), the somatosensory cortex (ssc), the motor cortex (mc), and the ca1 region of the hippocampus (hp), 9-day-old male gad-67-egfp transgenic mice were subjected to a 24 h md. |
2025-03-13 |
2025-03-15 |
mouse |
| Lequan Song, Zhiwei He, Ji Dong, Haoyu Wang, Jing Zhang, Binwei Yao, Xinping Xu, Hui Wang, Li Zhao, Ruiyun Pen. THz Waves Improve Spatial Working Memory by Increasing the Activity of Glutamatergic Neurons in Mice. Cells. vol 14. issue 5. 2025-03-12. PMID:40072098. |
spatial working memory, a critical component of higher cognitive function, is coordinated by brain regions such as the infralimbic cortex (il) region of the medial prefrontal cortex and the ventral cornu ammonis 1 (vca1) of hippocampus. |
2025-03-12 |
2025-03-14 |
mouse |
| Lilit Darbinyan, Karen Simonyan, Lilia Hambardzumyan, Larisa Manukyan, Kristine Karapetyan, Margarita Danielya. Impact of L-thyroxine on hippocampal activity, morphology, and behavioral performance in thyroidectomized rats. Metabolic brain disease. vol 40. issue 3. 2025-03-10. PMID:40063269. |
results revealed significant changes in hippocampal electrophysiological responses in the l-thyroxine-treated group, including enhanced synaptic plasticity, increased excitatory activity, and more frequent, synchronized neuronal firing in the ca1 and ca3 regions. |
2025-03-10 |
2025-03-13 |
rat |
| Lisa Traunmüller, Erin E Duffy, Hanqing Liu, Stella Sanalidou, Elena G Assad, Senmiao Sun, Naeem S Pajarillo, Nancy Niu, Eric C Griffith, Michael E Greenber. Novel environment exposure drives temporally defined and region-specific chromatin accessibility and gene expression changes in the hippocampus. bioRxiv : the preprint server for biology. 2025-03-10. PMID:40060638. |
we employed single- nucleus multiomics (snrna- and atac-seq) and bulk rna-seq of the hippocampal dg, ca3, and ca1 regions to characterize the temporal evolution of cell-type-specific chromatin accessibility and gene expression changes that occur in 14 different cell types of the hippocampus upon exposure of mice to a novel environment. |
2025-03-10 |
2025-03-12 |
mouse |
| Ting Zhao, Xiaoxiao Cui, Xinru Zhang, Mengke Zhao, Yousef Rastegar-Kashkooli, Junyang Wang, Qiang Li, Chao Jiang, Nan Li, Fei Xing, Na Xing, Junmin Wang, Jian Wan. Hippocampal Sclerosis: A Review on Current Research Status and Its Mechanisms. Ageing research reviews. 2025-03-09. PMID:40058463. |
hs of aging (hs-aging), a condition linked to dementia in the ultra-elderly, is marked by severe ca1 (cornu ammonis) neuronal loss and frequent transactive response dna-binding protein of 43kda (tdp-43) proteinopathy, often misdiagnosed as alzheimer's disease (ad). |
2025-03-09 |
2025-03-12 |
Not clear |
| Ekaterina V Fedorova, Irina Yu Chernomorets, Dmitry A Fedorov, Vladimir I Arkhipo. Delayed treatment with TGF-β1 associated neuroprotection in trimethyltin-induced hippocampal neurodegeneration. Neuroscience letters. 2025-03-06. PMID:40049360. |
in the passive avoidance test, tgf-β1 ameliorated tmt-induced long-term memory impairment and promoted neuronal preservation in the ca1 region of the hippocampus, although no such effect was observed in the ca3 and ca4 regions. |
2025-03-06 |
2025-03-09 |
rat |
| Ryan K Shahidehpour, Peter T Nelson, Sukanya Srinivasan, Zhong Yu, Adam D Bachstette. Assessing Co-Localization of ITM2B With Alzheimer's Disease and Limbic-Predominant Age-Related TDP-43 Encephalopathy Neuropathologic Changes. Neuropathology : official journal of the Japanese Society of Neuropathology. 2025-03-05. PMID:40042444. |
we investigated the patterns and co-localizations of itm2b immunohistochemistry in subiculum, ca1, ca2, ca3 and dentate gyrus of the hippocampus from brains with alzheimer's disease neuropathologic changes (adnc), late-nc, and comorbid adnc+late-nc, as well as low-pathology controls (n = 4 per disease state). |
2025-03-05 |
2025-03-07 |
Not clear |
| Janine I Rossato, Maria Carolina Gonzalez, Gênedy Apolinário, Andressa Radiske, Elis Brisa, Livia Maria Carneiro, Martín Cammarot. Hippocampal CaMKII Regulates the Consolidation of Recognition Memory. The European journal of neuroscience. vol 61. issue 5. 2025-03-03. PMID:40029612. |
we found that, in rats, training in an orm inducing learning task rapidly increased camkii autophosphorylation in the ca1 region of the dorsal hippocampus. |
2025-03-03 |
2025-03-06 |
rat |
| Shuhan Wang, Yaqi Yang, Jiahong Lin, Weishan Zhang, Cuizhu Yang, Runheng Zhang, Chang Zhou, Li Zhang, Xin Wang, Jing Liu, Xiaobao Jin, Yuxin M. Astragalin actives autophagy and inhibits apoptosis of astrocytes in AD mice via down-regulating Fas/Fasl-VDAC1 pathway. Free radical biology & medicine. 2025-03-03. PMID:40032030. |
in this study, we used the ad mice model established by injecting the mixture of aβ1-42 and aβ25-35 into the ca1 region of the hippocampus, and c8d1a cells injured by aβ1-42 to explore the neuroprotective effects of ast. |
2025-03-03 |
2025-03-06 |
mouse |
| Julio Esparza, Juan Pablo Quintanilla, Elena Cid, Ana C Medeiros, Juan A Gallego, Liset Menendez de la Prid. Cell-type-specific manifold analysis discloses independent geometric transformations in the hippocampal spatial code. Neuron. 2025-02-27. PMID:40015277. |
we investigated this question by focusing on hippocampal spatial maps and the contribution of two genetically defined pyramidal cell types in the deep and superficial ca1 sublayers. |
2025-02-27 |
2025-03-02 |
mouse |
| Filip P Dybowski, Daniel S Scott, Carol A Tamming. Pharmacological reduction of reverse-translated hippocampal hyperactivity in mouse: relevance for psychosis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2025-02-27. PMID:40016366. |
all animals received one of the four treatments: vehicle (n = 15-24), haloperidol (n = 8-15), xanomeline (n = 8-13) or levetiracetam (n = 6-15) and were subsequently tested for baseline c-fos protein expression within the hippocampal subfields (ca3 and ca1) as a measure of neuronal activity, or tested with the srm task as a measure of social memory. |
2025-02-27 |
2025-03-02 |
mouse |
| Tao Q. The effects of amyloidosis and aging on glutamatergic and GABAergic synapses, and interneurons in the barrel cortex and non-neocortical brain regions. Frontiers in neuroanatomy. vol 19. 2025-02-27. PMID:40012738. |
therefore, in this study, we utilized ad and aging mouse models to investigate the e/i balance and the distribution of parvalbumin (pv)- and somatostatin (sst)-expressing cells in s1bf (barrel field of primary somatosensory cortex, barrel cortex), ca1 hippocampal area and brain regions beyond the neocortex and hippocampus, including retrosplenial cortex (rsc, which is composed of rsg and rsa), piriform cortex (pir), amygdala (bma), and hypothalamus (dm). |
2025-02-27 |
2025-03-01 |
mouse |
| Xin-Ling Wang, Yan-Bin Ji, Su-Xia Li, Tsvetan Sercho. The crosstalk between CREB and PER2 mediates the transition between mania- and depression-like behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2025-02-26. PMID:40011706. |
utilizing a mania animal model induced by ouabain, we observed reduced phosphorylated level of cyclic amp-responsive element-binding protein (pcreb) and period (per)2 expression in the cornu ammonis (ca1) region of the hippocampus, which were restored by lithium treatment. |
2025-02-26 |
2025-03-01 |
Not clear |
| Daniel English, Earl Gilbert, Lianne Klaver, Kaiser Arndt, Jongwoon Kim, Xiaoting Jia, Sam Mckenzi. Reciprocal interactions between CA1 pyramidal and axo-axonic cells control sharp wave-ripple events. Research square. 2025-02-24. PMID:39989976. |
for example, in hippocampus area ca1 the competition between inhibition and excitation organizes spike timing of pyramidal cells (pyr) in network events, including sharp wave-ripples (spw-r). |
2025-02-24 |
2025-02-26 |
mouse |
| Ze-Cong He, Ya-Jie Yu, Ting Wang, Hui-Rong Yin, Ya-Xin Sun, Xiao Liu, Xiao-Meng Xie, Hong-Li Wang, Yun-Ai Su, Ji-Tao Li, Tian-Mei S. Early-life stress of limited bedding/nesting material induced recognition memory loss and decreased hippocampal VGluT1 and nectin3 levels in aged male mice. Pharmacology, biochemistry, and behavior. 2025-02-23. PMID:39987993. |
these cognitive deficits were accompanied by a reduction in vglut1 expression and a lower vglut1/vgat ratio in the ca1 region of the hippocampus, as well as reduced nectin3 expression in the mouse hippocampus. |
2025-02-23 |
2025-02-26 |
mouse |
| Raheleh Rafaiee, Fahimeh Mohseni, Mehdi Khaksari, Behzad Garmabi, Alireza Masoudi, Zhaleh Jamali, Shima Mohammadi, Alieh Bashghare. Erythropoietin Improves Spatial and Nonspatial Memory Defects by Suppressing Oxidative Damage, Inflammation and Apoptosis against Ethanol Neurotoxicity in the Developing Male Rat Hippocampus. Peptides. 2025-02-21. PMID:39983919. |
epo dramatically decreased the amount of caspase 3 positive cells in the ca1 area of the hippocampus (p < 0.01). |
2025-02-21 |
2025-02-24 |
rat |
| Yuanyuan Hou, Yao Zuo, Shaofei Song, Tong Zhan. Long-term variable photoperiod exposure impairs hippocampal synapse involving of the glutamate system and leads to memory deficits in male Wistar rats. Experimental neurology. 2025-02-19. PMID:39971149. |
to investigate the impact of circadian misalignment on hippocampal function, we measured various field excitatory postsynaptic potentials (fepsp) and golgi staining in the ca1 and dentate gyrus (dg) regions in wistar rats. |
2025-02-19 |
2025-02-23 |
human |
| David J Horovitz, Laura A Askins, Grace M Regnier, Joseph A McQuai. Age-related synaptic signatures of brain and cognitive reserve in the rat hippocampus and parahippocampal regions. Neurobiology of aging. vol 148. 2025-02-15. PMID:39954409. |
higher levels of the vesicular gaba transporter (vgat) were associated with better spatial learning in older rats, across several synaptic zones of the dorsal hippocampus, including the outer molecular layer of the dentate gyrus (dg), and the so, sr, slm, and pyramidal cell layers of both ca3 and ca1. |
2025-02-15 |
2025-02-18 |
rat |
| Mzia G Zhvania, Irina Sharikadze, Nadezhda Japaridze, Yousef Tizabi, Fuad Rzayev, Eldar Gasimov, Giorgi Lobzhanidz. Status epilepticus alters hippocampal ultrastructure in kainic acid rat model. Tissue & cell. vol 94. 2025-02-15. PMID:39954563. |
the findings suggest a time-dependent ultrastructural changes in ca1 region of the hippocampus in an animal model of focal epilepsy. |
2025-02-15 |
2025-02-18 |
rat |
| María C Gutiérrez, Ramiro G Comas Mutis, María C Perondi, Gastón D Calfa, Analía Valdomer. Perinatal Protein Restriction Induces Anhedonic-Like Behavior: Disturbed Hippocampal Neurotrophic Signaling and Neuronal Structural Plasticity in Adult Offspring. Hippocampus. vol 35. issue 2. 2025-02-14. PMID:39949067. |
this study explored how maternal protein restriction contributes to anhedonia, a key depression symptom, focusing on the hippocampal bdnf-trkb signaling and structural plasticity changes in the ca1 subregion of the dorsal hippocampus (dh). |
2025-02-14 |
2025-02-16 |
rat |