| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kristy J Szretter, Melanie A Samuel, Susan Gilfillan, Anja Fuchs, Marco Colonna, Michael S Diamon. The immune adaptor molecule SARM modulates tumor necrosis factor alpha production and microglia activation in the brainstem and restricts West Nile Virus pathogenesis. Journal of virology. vol 83. issue 18. 2009-10-02. PMID:19587044. |
a deficiency of sarm was also linked to reduced levels of tumor necrosis factor alpha (tnf-alpha), decreased microglia activation, and increased neuronal death in the brainstem after wnv infection. |
2009-10-02 |
2023-08-12 |
mouse |
| Gerlinda E Hermann, Richard C Roger. TNFalpha: a trigger of autonomic dysfunction. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 14. issue 1. 2008-03-05. PMID:17911224. |
our studies have focused on how tnf alpha produces a profound gastric stasis by acting on vago-vagal reflex circuits in the brainstem. |
2008-03-05 |
2023-08-12 |
Not clear |
| Carlota González Inchauspe, Ian D Forsythe, Osvaldo D Uchite. Changes in synaptic transmission properties due to the expression of N-type calcium channels at the calyx of Held synapse of mice lacking P/Q-type calcium channels. The Journal of physiology. vol 584. issue Pt 3. 2008-01-09. PMID:17823210. |
using whole-cell patch clamping from in vitro slices of the auditory brainstem we have examined presynaptic calcium currents (i(pca)) and glutamatergic excitatory postsynaptic currents (epscs) at the calyx of held synapse from transgenic mice in which the alpha(1a) pore-forming subunit of the p/q-type ca(2+) channels is ablated (ko). |
2008-01-09 |
2023-08-12 |
mouse |
| Elba Alonso, Elisa Garrido, Carmen Díez-Fernández, Carmen Pérez-García, Gonzalo Herradón, Laura Ezquerra, Thomas F Deuel, Luis F Alguaci. Yohimbine prevents morphine-induced changes of glial fibrillary acidic protein in brainstem and alpha2-adrenoceptor gene expression in hippocampus. Neuroscience letters. vol 412. issue 2. 2007-04-03. PMID:17123717. |
in addition, drug effects on alpha(2)-adrenoceptor gene expression were determined by real time rt-pcr in the hippocampus, a brain area that receives noradrenergic input from the brainstem. |
2007-04-03 |
2023-08-12 |
rat |
| V Ani Das, Finla Chathu, C S Paulos. Decreased alpha2-adrenergic receptor in the brain stem and pancreatic islets during pancreatic regeneration in weanling rats. Life sciences. vol 79. issue 16. 2006-11-06. PMID:16737719. |
we investigated the changes in the alpha(2)-adrenergic receptors in the brain stem and pancreatic islets using [(3)h]yohimbine during pancreatic regeneration in weanling rats. |
2006-11-06 |
2023-08-12 |
rat |
| Qiuli Liu, Margaret T T Wong-Rile. Developmental changes in the expression of GABAA receptor subunits alpha1, alpha2, and alpha3 in brain stem nuclei of rats. Brain research. vol 1098. issue 1. 2006-10-24. PMID:16750519. |
despite differences in timing, gaba(a) alpha subunit switching may be a common theme in the brain stem that may mediate different functional properties of gaba transmission. |
2006-10-24 |
2023-08-12 |
rat |
| C R Maxwell, Y Liang, M P Kelly, S J Kanes, T Abel, S J Siege. Mice expressing constitutively active Gsalpha exhibit stimulus encoding deficits similar to those observed in schizophrenia patients. Neuroscience. vol 141. issue 3. 2006-10-18. PMID:16750890. |
we find that g(s)alpha transgenic mice have decreased amplitude of cortically generated n40 but normal acoustic brainstem response amplitude, consistent with forebrain transgene expression and a schizophrenia endophenotype. |
2006-10-18 |
2023-08-12 |
mouse |
| D Huber, F-J Kret. [Efficacy of clonidine in paediatric anaesthesia]. Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS. vol 40. issue 10. 2005-12-20. PMID:16252217. |
yet clonidine also has a sedative effect due to alpha (2)-adrenoceptor stimulation in the locus coeruleus and antinociceptive action caused through postjunctional noradrenergic pathways in the brainstem and spinal cord. |
2005-12-20 |
2023-08-12 |
Not clear |
| G E Hermann, G M Holmes, R C Roger. TNF(alpha) modulation of visceral and spinal sensory processing. Current pharmaceutical design. vol 11. issue 11. 2005-05-24. PMID:15853670. |
we have demonstrated that tnf(alpha) can elicit gastric stasis in a dose-dependent fashion via its interaction with vago-vagal neurocircuitry in the brainstem. |
2005-05-24 |
2023-08-12 |
Not clear |
| Daisuke Tsuji, Aya Kuroki, Yasuhiro Ishibashi, Tomohiro Itakura, Jun Kuwahara, Shoji Yamanaka, Kohji Ito. Specific induction of macrophage inflammatory protein 1-alpha in glial cells of Sandhoff disease model mice associated with accumulation of N-acetylhexosaminyl glycoconjugates. Journal of neurochemistry. vol 92. issue 6. 2005-04-22. PMID:15748167. |
we demonstrated that chemokine macrophage inflammatory protein-1 alpha (mip-1alpha) was induced in brain regions, including the cerebral cortex, brain stem and cerebellum, of sd mice from an early stage of the pathogenesis but not in other systemic organs. |
2005-04-22 |
2023-08-12 |
mouse |
| Theodore A Slotkin, Mandy M Cousins, Frederic J Seidle. Administration of nicotine to adolescent rats evokes regionally selective upregulation of CNS alpha 7 nicotinic acetylcholine receptors. Brain research. vol 1030. issue 1. 2005-02-03. PMID:15567348. |
we administered nicotine to adolescent rats and evaluated the effects on alpha 7 nachrs in the striatum, brainstem and cerebellum. |
2005-02-03 |
2023-08-12 |
rat |
| Theodore A Slotkin, Mandy M Cousins, Frederic J Seidle. Administration of nicotine to adolescent rats evokes regionally selective upregulation of CNS alpha 7 nicotinic acetylcholine receptors. Brain research. vol 1030. issue 1. 2005-02-03. PMID:15567348. |
during the period of nicotine administration (30-47.5 days of age), nicotine elicited alpha 7 nachr upregulation with a regional hierarchy of striatum>brainstem>cerebellum. |
2005-02-03 |
2023-08-12 |
rat |
| H Kevin Happe, Barbara J Morle. Distribution and postnatal development of alpha 7 nicotinic acetylcholine receptors in the rodent lower auditory brainstem. Brain research. Developmental brain research. vol 153. issue 1. 2004-12-21. PMID:15464215. |
distribution and postnatal development of alpha 7 nicotinic acetylcholine receptors in the rodent lower auditory brainstem. |
2004-12-21 |
2023-08-12 |
mouse |
| Marina A J Tijssen, Peter Brown, David MacManus, Mary A McLean, Charles Davi. Magnetic resonance spectroscopy of cerebral cortex is normal in hereditary hyperekplexia due to mutations in the GLRA1 gene. Movement disorders : official journal of the Movement Disorder Society. vol 18. issue 12. 2004-04-28. PMID:14673895. |
six patients with hereditary hyperekplexia (hh) and a confirmed mutation in the gene encoding the alpha(1) subunit of the glycine receptor (glra1) underwent single voxel (1)h magnetic resonance spectroscopy (mrs) of the brainstem and an area of frontal cortex and white matter using a method that allows absolute quantification of metabolites. |
2004-04-28 |
2023-08-12 |
Not clear |
| J Motsch, M Kamle. [Alpha 2-adrenergic agonists. Use in chronic pain--a meta-analysis]. Schmerz (Berlin, Germany). vol 11. issue 5. 2004-03-24. PMID:12799805. |
alpha(2)-adrenergic agonists, mimicking the action of the inhibitory transmitter norepinephrine, cause antinociception due to postsynaptic inhibition of spinothalamic projection neurons, presynaptic inhibition at the central nervous system termination of primary sensory nerves, presynaptic inhibition of brainstem noradrenergic neurons and a generalized decrease in central nervous system sympathetic efferent activity. |
2004-03-24 |
2023-08-12 |
Not clear |
| Tao Chen, Yuan-Xiang Dong, Yun-Qing L. Fos expression in serotonergic neurons in the rat brainstem following noxious stimuli: an immunohistochemical double-labelling study. Journal of anatomy. vol 203. issue 6. 2004-02-24. PMID:14686693. |
the expression of fos protein in 5-ht-containing neurons (5-ht/fos co-localized neurons) could be observed in the ventrolateral subdivision of the midbrain periaqueductal grey, interpeduncular nucleus, paramedian raphe nucleus, all of the brainstem raphe nuclei, the alpha part of the gigantocellular reticular nucleus and the lateral paragigantocellular reticular nucleus. |
2004-02-24 |
2023-08-12 |
rat |
| Giovanni Cucchiaro, Kathryn G Common. Alpha 4 nicotinic acetylcholine receptor subunit links cholinergic to brainstem monoaminergic neurotransmission. Synapse (New York, N.Y.). vol 49. issue 3. 2003-10-07. PMID:12774304. |
alpha 4 nicotinic acetylcholine receptor subunit links cholinergic to brainstem monoaminergic neurotransmission. |
2003-10-07 |
2023-08-12 |
Not clear |
| Gorazd Bunc, Srecko Kovacic, Simona Strna. Attenuation of cerebral vasospasm in rabbits using clonidine hydrochloride, a central adrenergic agonist. Autonomic neuroscience : basic & clinical. vol 105. issue 1. 2003-07-24. PMID:12742193. |
the results of this study demonstrated that the central alpha(2)-blocker clonidine hydrochloride effectively prevents vasospasm, and diminishes the concentration of cerebral dopamine beta-hydroxylase in the hypothalamus and brain stem after experimental subarachnoid haemorrhage in rabbits. |
2003-07-24 |
2023-08-12 |
rabbit |
| Bela Szab. Imidazoline antihypertensive drugs: a critical review on their mechanism of action. Pharmacology & therapeutics. vol 93. issue 1. 2002-09-10. PMID:11916539. |
it was long thought that the prototypical centrally acting antihypertensive drug clonidine lowers sympathetic tone by activating alpha(2)-adrenoceptors in the brain stem. |
2002-09-10 |
2023-08-12 |
Not clear |
| R S Bitner, A L Nikke. Alpha-7 nicotinic receptor expression by two distinct cell types in the dorsal raphe nucleus and locus coeruleus of rat. Brain research. vol 938. issue 1-2. 2002-08-08. PMID:12031534. |
using an antibody against the alpha 7 nachr subunit, immunohistochemical staining was observed in rat dorsal raphe nucleus (drn) and locus coeruleus (lc), serotonergic and noradrenergic brainstem nuclei, respectively. |
2002-08-08 |
2023-08-12 |
rat |