| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lee Tran, N Bradley Keel. P-chlorophenylalanine increases glutamate receptor 1 transcription in rat amygdala. Neuroreport. vol 22. issue 15. 2012-01-13. PMID:21876464. |
using quantitative reverse transcriptase-polymerase chain reaction, we found that rats treated with p-chlorophenylalanine, an inhibitor of tyrosine-5-hydroxylase, resulted in a 21-fold increase in glutamate receptor 1 (glur1) mrna expression in the amygdala. |
2012-01-13 |
2023-08-12 |
rat |
| Andreas Pikwe. Depersonalization disorder may be related to glutamate receptor activation imbalance. Medical hypotheses. vol 77. issue 4. 2011-12-29. PMID:21742442. |
glutamate release in prefrontal cortex is increased by subanaesthetic doses of ketamine, resulting in increased inhibition, possibly via intercalated gabaerg cells, of projections from amygdala, affecting structures critically involved in depersonalization. |
2011-12-29 |
2023-08-12 |
Not clear |
| Andreas Pikwe. Depersonalization disorder may be related to glutamate receptor activation imbalance. Medical hypotheses. vol 77. issue 4. 2011-12-29. PMID:21742442. |
i speculate that, in depersonalization disorder, the increased glutamate activity in prefrontal cortex is due to intrinsic imbalance, resulting in long-term potentiation, at the postsynaptic glutamate receptors on the gabaerg interneurons while the same receptor abnormality at the synapses on the intercalated gabaerg cells of the amygdala result in long-term depression in the case of either normal or high glutamate release. |
2011-12-29 |
2023-08-12 |
Not clear |
| Stéphanie Graebenitz, Olga Kedo, Erwin-Josef Speckmann, Ali Gorji, Heinz Panneck, Volkmar Hans, Nicola Palomero-Gallagher, Axel Schleicher, Karl Zilles, Hans-Christian Pap. Interictal-like network activity and receptor expression in the epileptic human lateral amygdala. Brain : a journal of neurology. vol 134. issue Pt 10. 2011-12-15. PMID:21893592. |
receptor autoradiographic analysis revealed significantly higher α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid, kainate, metabotropic glutamate type 2/3, muscarinic type 2 and adrenoceptor α(1) densities, whereas muscarinergic type 3 and serotonergic type 1a receptor densities were lower in the lateral amygdala from epileptic patients in comparison to autopsy controls. |
2011-12-15 |
2023-08-12 |
human |
| Stéphanie Graebenitz, Olga Kedo, Erwin-Josef Speckmann, Ali Gorji, Heinz Panneck, Volkmar Hans, Nicola Palomero-Gallagher, Axel Schleicher, Karl Zilles, Hans-Christian Pap. Interictal-like network activity and receptor expression in the epileptic human lateral amygdala. Brain : a journal of neurology. vol 134. issue Pt 10. 2011-12-15. PMID:21893592. |
together these data indicate an abnormal pattern of receptor densities and synaptic function in the lateral nucleus of the amygdala in epileptic patients, involving critical alterations in glutamate and γ-aminobutyric acid receptors, which may give rise to domains of spontaneous interictal discharges contributing to seizure activity in the amygdala. |
2011-12-15 |
2023-08-12 |
human |
| A Galanopoulos, A Polissidis, Z Papadopoulou-Daifoti, G G Nomikos, K Antonio. Δ(9)-THC and WIN55,212-2 affect brain tissue levels of excitatory amino acids in a phenotype-, compound-, dose-, and region-specific manner. Behavioural brain research. vol 224. issue 1. 2011-11-21. PMID:21645556. |
the aim of the present study was to investigate the effects of the cannabinoid agonists, Δ(9)-thc and win55,212-2, on tissue (prefrontal cortex, dorsal striatum, nucleus accumbens, hippocampus, amygdala and hypothalamus) levels of glutamate and aspartate in two rat phenotypes, high responders (hr) and low responders (lr), differentiated according to their response to a novel environment. |
2011-11-21 |
2023-08-12 |
rat |
| A Galanopoulos, A Polissidis, Z Papadopoulou-Daifoti, G G Nomikos, K Antonio. Δ(9)-THC and WIN55,212-2 affect brain tissue levels of excitatory amino acids in a phenotype-, compound-, dose-, and region-specific manner. Behavioural brain research. vol 224. issue 1. 2011-11-21. PMID:21645556. |
the cannabinoids primarily increased glutamate levels in the prefrontal cortex, dorsal striatum, nucleus accumbens and hippocampus, while the high dose of win55,212-2 decreased glutamate levels in the amygdala and both doses in the hypothalamus; these effects appeared overall more pronounced in hr. |
2011-11-21 |
2023-08-12 |
rat |
| Carolina Böettge Rosa, Jéferson F Goularte, Nathália A Trindade, Alexandre P De Oliveira, Alberto A Rasia-Filh. Glutamate microinjected in the posterodorsal medial amygdala induces subtle increase in the consumption of a three-choice macronutrient self-selection diet in male rats. Anatomical record (Hoboken, N.J. : 2007). vol 294. issue 7. 2011-10-25. PMID:21634022. |
glutamate microinjected in the posterodorsal medial amygdala induces subtle increase in the consumption of a three-choice macronutrient self-selection diet in male rats. |
2011-10-25 |
2023-08-12 |
rat |
| Roberto Romero González, Remedios Fernández Fernández, José Luis Martínez Vidal, Antonia Garrido Frenich, María Luz Gómez Pére. Development and validation of an ultra-high performance liquid chromatography-tandem mass-spectrometry (UHPLC-MS/MS) method for the simultaneous determination of neurotransmitters in rat brain samples. Journal of neuroscience methods. vol 198. issue 2. 2011-10-07. PMID:21459108. |
therefore, the method was successfully applied for the quantitative determination of neurotransmitters in several rat brain regions (prefrontal cortex, striatum, nucleus accumbens and amygdala), detecting glutamate, gaba and choline at concentrations higher than 1000 μg/g, 30 μg/g and 100 μg/g respectively, whereas the other compounds were found at lower concentrations. |
2011-10-07 |
2023-08-12 |
rat |
| Anke Tappe-Theodor, Yu Fu, Rohini Kuner, Volker Neugebaue. Homer1a signaling in the amygdala counteracts pain-related synaptic plasticity, mGluR1 function and pain behaviors. Molecular pain. vol 7. 2011-09-12. PMID:21595930. |
group i metabotropic glutamate receptor (mglur1/5) signaling is an important mechanism of pain-related plasticity in the amygdala that plays a key role in the emotional-affective dimension of pain. |
2011-09-12 |
2023-08-12 |
mouse |
| Justin T Gass, Courtney M Sinclair, Richard M Cleva, John J Widholm, M Foster Oliv. Alcohol-seeking behavior is associated with increased glutamate transmission in basolateral amygdala and nucleus accumbens as measured by glutamate-oxidase-coated biosensors. Addiction biology. vol 16. issue 2. 2011-07-20. PMID:21054692. |
alcohol-seeking behavior is associated with increased glutamate transmission in basolateral amygdala and nucleus accumbens as measured by glutamate-oxidase-coated biosensors. |
2011-07-20 |
2023-08-12 |
rat |
| Enza Palazzo, Ida Marabese, Marie Soukupova, Livio Luongo, Serena Boccella, Catia Giordano, Vito de Novellis, Francesca Rossi, Sabatino Maion. Metabotropic glutamate receptor subtype 8 in the amygdala modulates thermal threshold, neurotransmitter release, and rostral ventromedial medulla cell activity in inflammatory pain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 12. 2011-05-27. PMID:21430167. |
metabotropic glutamate receptor subtype 8 in the amygdala modulates thermal threshold, neurotransmitter release, and rostral ventromedial medulla cell activity in inflammatory pain. |
2011-05-27 |
2023-08-12 |
rat |
| Simon J Fung, Mingchu Xi, Jianhua Zhang, Pablo Torterolo, Sharon Sampogna, Francisco R Morales, Michael H Chas. Projection neurons from the central nucleus of the amygdala to the nucleus pontis oralis. Journal of neuroscience research. vol 89. issue 3. 2011-05-03. PMID:21259329. |
sections of the amygdala were immunostained in order to identify ctb-labeled cna neurons and cna neurons that contained ctb plus the vesicular glutamate transporter 2 (vglut2), which is a marker for glutamatergic neurons. |
2011-05-03 |
2023-08-12 |
Not clear |
| Małgorzata Lehner, Aleksandra Wisłowska-Stanek, Ewa Taracha, Piotr Maciejak, Janusz Szyndler, Anna Skórzewska, Danuta Turzyńska, Alicja Sobolewska, Adam Hamed, Andrzej Bidziński, Adam Płaźni. The effects of midazolam and D-cycloserine on the release of glutamate and GABA in the basolateral amygdala of low and high anxiety rats during extinction trial of a conditioned fear test. Neurobiology of learning and memory. vol 94. issue 4. 2011-02-28. PMID:20807585. |
the effects of midazolam and d-cycloserine on the release of glutamate and gaba in the basolateral amygdala of low and high anxiety rats during extinction trial of a conditioned fear test. |
2011-02-28 |
2023-08-12 |
rat |
| Małgorzata Lehner, Aleksandra Wisłowska-Stanek, Ewa Taracha, Piotr Maciejak, Janusz Szyndler, Anna Skórzewska, Danuta Turzyńska, Alicja Sobolewska, Adam Hamed, Andrzej Bidziński, Adam Płaźni. The effects of midazolam and D-cycloserine on the release of glutamate and GABA in the basolateral amygdala of low and high anxiety rats during extinction trial of a conditioned fear test. Neurobiology of learning and memory. vol 94. issue 4. 2011-02-28. PMID:20807585. |
in these rats, we examined the effects of both drugs on the release of glutamate and gaba in the basolateral amygdala (bla) during the first extinction trial of a conditioned fear test. |
2011-02-28 |
2023-08-12 |
rat |
| Zhen Li, Guangchen Ji, Volker Neugebaue. Mitochondrial reactive oxygen species are activated by mGluR5 through IP3 and activate ERK and PKA to increase excitability of amygdala neurons and pain behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 3. 2011-02-23. PMID:21248136. |
neuroplasticity in the amygdala plays a key role in emotional-affective pain responses and depends on group i metabotropic glutamate receptors (mglurs) and protein kinases. |
2011-02-23 |
2023-08-12 |
Not clear |
| Piotr Maciejak, Janusz Szyndler, Danuta Turzyńska, Alicja Sobolewska, Andrzej Bidziński, Karolina Kołosowska, Adam Płaźni. Time course of changes in the concentrations of amino acids in the brain structures of pentylenetetrazole-kindled rats. Brain research. vol 1342. 2011-01-18. PMID:20420810. |
at the fifth stage of kindling, glutamate was elevated in the amygdala, nucleus accumbens and piriform cortex, whereas alanine content was increased in the hippocampus, amygdala, striatum, nucleus accumbens and piriform cortex. |
2011-01-18 |
2023-08-12 |
rat |
| Guangchen Ji, Volker Neugebaue. Reactive oxygen species are involved in group I mGluR-mediated facilitation of nociceptive processing in amygdala neurons. Journal of neurophysiology. vol 104. issue 1. 2011-01-07. PMID:20463194. |
hyperactivity of amygdala neurons in an animal pain model depends on group i metabotropic glutamate receptors (subtypes mglur1 and mglur5), but their signaling pathway remains to be determined. |
2011-01-07 |
2023-08-12 |
rat |
| Brian A McCool, Daniel T Christian, Marvin R Diaz, Anna K Läc. Glutamate plasticity in the drunken amygdala: the making of an anxious synapse. International review of neurobiology. vol 91. 2010-12-21. PMID:20813244. |
glutamate plasticity in the drunken amygdala: the making of an anxious synapse. |
2010-12-21 |
2023-08-12 |
Not clear |
| Brian A McCool, Daniel T Christian, Marvin R Diaz, Anna K Läc. Glutamate plasticity in the drunken amygdala: the making of an anxious synapse. International review of neurobiology. vol 91. 2010-12-21. PMID:20813244. |
classic fear conditioning, for example, is dependent upon nmda-type glutamate receptor activation in the lateral/basolateral amygdala followed by increased synaptic expression of ampa-type glutamate receptors. |
2010-12-21 |
2023-08-12 |
Not clear |