Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Antonio Riccio, Yan Li, Evgeny Tsvetkov, Svetlana Gapon, Gui Lan Yao, Kiersten S Smith, Elif Engin, Uwe Rudolph, Vadim Y Bolshakov, David E Clapha. Decreased anxiety-like behavior and Gαq/11-dependent responses in the amygdala of mice lacking TRPC4 channels. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 10. 2014-04-29. PMID:24599464. |
recordings in brain slices demonstrated that these behavioral modifications could stem from the lack of trpc4 potentiation in neurons in the lateral nucleus of the amygdala through two gαq/11 protein-coupled signaling pathways, activated via group i metabotropic glutamate receptors and cholecystokinin 2 receptors, respectively. |
2014-04-29 |
2023-08-12 |
mouse |
Marc A Beckerman, Evgeny Ogorodnik, Michael J Glas. Acute morphine associated alterations in the subcellular location of the AMPA-GluR1 receptor subunit in dendrites of neurons in the mouse central nucleus of the amygdala: comparisons and contrasts with other glutamate receptor subunits. Synapse (New York, N.Y.). vol 67. issue 10. 2014-02-21. PMID:23564315. |
within the amygdala, ampa receptors expressing the ampa-glur1 (glur1) subunit play an important role in basal glutamate signaling as well as behaviors associated with exposure to drugs of abuse like opiates. |
2014-02-21 |
2023-08-12 |
mouse |
Markus Fendt, Stefan Imobersteg, Daniel Peterlik, Frédérique Chaperon, Catherine Mattes, Christina Wittmann, Hans-Rudolf Olpe, Johannes Mosbacher, Ivo Vranesic, Herman van der Putten, Kevin H McAllister, Peter J Flor, Christine E Ge. Differential roles of mGlu(7) and mGlu(8) in amygdala-dependent behavior and physiology. Neuropharmacology. vol 72. 2014-02-11. PMID:23664812. |
glutamate transmission and synaptic plasticity in the amygdala are essential for the learning and expression of conditioned fear. |
2014-02-11 |
2023-08-12 |
mouse |
Yuan Liang, Xiao-Ling Guo, Jia-Xu Chen, Guang-Xin Yu. Effects of the chinese traditional prescription xiaoyaosan decoction on chronic immobilization stress-induced changes in behavior and ultrastructure in rat hippocampus. Evidence-based complementary and alternative medicine : eCAM. vol 2013. 2014-01-01. PMID:24381641. |
animals were randomly divided into five groups: (1) control group; (2) sham-operated group; (3) cis group, in which rats were conducted cis for 21 days; (4) xys decoction treatment group; (5) 6-cyano-7-nitroquinoxaline-2,3-dione (cnqx) positive group, in which the amygdala of cis rats was unilaterally microinjected with a competitive glutamate receptor antagonist, cnqx. |
2014-01-01 |
2023-08-12 |
rat |
David S Tukey, Michelle Lee, Duo Xu, Sarah E Eberle, Yossef Goffer, Toby R Manders, Edward B Ziff, Jing Wan. Differential effects of natural rewards and pain on vesicular glutamate transporter expression in the nucleus accumbens. Molecular brain. vol 6. 2013-11-27. PMID:23835161. |
glutamate inputs to the nac arise primarily from prefrontal cortex, thalamus, amygdala, and hippocampus, and different glutamate projections provide distinct synaptic and ultimately behavioral functions. |
2013-11-27 |
2023-08-12 |
Not clear |
József Kiss, Zsolt Csaba, Agnes Csáki, Béla Halás. Demonstration of estrogen receptor α protein in glutamatergic (vesicular glutamate transporter 2 immunoreactive) neurons of the female rat hypothalamus and amygdala using double-label immunocytochemistry. Experimental brain research. vol 226. issue 4. 2013-11-05. PMID:23543101. |
demonstration of estrogen receptor α protein in glutamatergic (vesicular glutamate transporter 2 immunoreactive) neurons of the female rat hypothalamus and amygdala using double-label immunocytochemistry. |
2013-11-05 |
2023-08-12 |
rat |
József Kiss, Zsolt Csaba, Agnes Csáki, Béla Halás. Demonstration of estrogen receptor α protein in glutamatergic (vesicular glutamate transporter 2 immunoreactive) neurons of the female rat hypothalamus and amygdala using double-label immunocytochemistry. Experimental brain research. vol 226. issue 4. 2013-11-05. PMID:23543101. |
by means of double-label immunocytochemistry, authors studied the presence of estrogen receptor α (er-α) protein in vesicular glutamate transporter 2 (vglut2) protein-immunoreactive neurons in the female rat hypothalamus and amygdala. |
2013-11-05 |
2023-08-12 |
rat |
Andrés A Trabanco, José María Ci. mGluR2 positive allosteric modulators: a patent review (2009 - present). Expert opinion on therapeutic patents. vol 23. issue 5. 2013-10-28. PMID:23452205. |
high levels of mglu2 receptors are seen in brain areas such as prefrontal cortex, hippocampus and amygdala where glutamate hyperfunction may be implicated in disorders and diseases such as anxiety and schizophrenia. |
2013-10-28 |
2023-08-12 |
Not clear |
Daniel T Christian, Nancy J Alexander, Marvin R Diaz, Brian A McCoo. Thalamic glutamatergic afferents into the rat basolateral amygdala exhibit increased presynaptic glutamate function following withdrawal from chronic intermittent ethanol. Neuropharmacology. vol 65. 2013-10-17. PMID:22982568. |
thalamic glutamatergic afferents into the rat basolateral amygdala exhibit increased presynaptic glutamate function following withdrawal from chronic intermittent ethanol. |
2013-10-17 |
2023-08-12 |
rat |
Daniel T Christian, Nancy J Alexander, Marvin R Diaz, Brian A McCoo. Thalamic glutamatergic afferents into the rat basolateral amygdala exhibit increased presynaptic glutamate function following withdrawal from chronic intermittent ethanol. Neuropharmacology. vol 65. 2013-10-17. PMID:22982568. |
these data demonstrate that chronic ethanol modulation of glutamate neurotransmission in the rat lateral/basolateral amygdala is afferent-specific. |
2013-10-17 |
2023-08-12 |
rat |
Sarah J Lucas, Zuner A Bortolotto, Graham L Collingridge, David Lodg. Selective activation of either mGlu2 or mGlu3 receptors can induce LTD in the amygdala. Neuropharmacology. vol 66. 2013-07-02. PMID:22531751. |
group ii metabotropic glutamate (mglu) receptors are known to induce a long-term depression (ltd) of synaptic transmission in many brain regions including the amygdala. |
2013-07-02 |
2023-08-12 |
mouse |
Livio Luongo, Vito de Novellis, Luisa Gatta, Enza Palazzo, Daniela Vita, Francesca Guida, Catia Giordano, Dario Siniscalco, Ida Marabese, Maria De Chiaro, Serena Boccella, Francesca Rossi, Sabatino Maion. Role of metabotropic glutamate receptor 1 in the basolateral amygdala-driven prefrontal cortical deactivation in inflammatory pain in the rat. Neuropharmacology. vol 66. 2013-07-02. PMID:22796105. |
we have here investigated the role of group i metabotropic glutamate receptors (mglurs) in the basolateral amygdala (bla) pre-infra-limbic (pl-il) divisions of the medial prefrontal cortex (mpfc) neuron connections after carrageenan-induced inflammatory pain in the rat. |
2013-07-02 |
2023-08-12 |
rat |
b' Katalin Adrienna K\\xc3\\xa9kesi, G\\xc3\\xa1bor Juh\\xc3\\xa1sz, Attila Simor, P\\xc3\\xa9ter Guly\\xc3\\xa1ssy, Eva M\\xc3\\xb3nika Szeg\\xc5\\x91, Eva Hunyadi-Guly\\xc3\\xa1s, Zsuzsanna Darula, Katalin F Medzihradszky, Mikl\\xc3\\xb3s Palkovits, Botond Penke, Andr\\xc3\\xa1s Czurk\\xc3\\xb. Altered functional protein networks in the prefrontal cortex and amygdala of victims of suicide. PloS one. vol 7. issue 12. 2013-06-26. PMID:23272063.' |
we also pointed out 9 proteins that changed in both the amygdala and the cortex, and from these, gfap, ina, nefl, nefm and tuba1 are interacting cytoskeletal proteins that have a functional connection to glutamate, gaba, and serotonin receptors. |
2013-06-26 |
2023-08-12 |
Not clear |
Fengyu Zhang, Bei Liu, Zhuofan Lei, Jin-Hui Wan. mGluR₁,5 activation improves network asynchrony and GABAergic synapse attenuation in the amygdala: implication for anxiety-like behavior in DBA/2 mice. Molecular brain. vol 5. 2013-06-21. PMID:22681774. |
using behavioral task, two-photon cellular imaging and electrophysiology, we studied the characteristics of neural networks in basolateral amygdala and the influences of metabotropic glutamate receptor (mglur) on their dynamics in dba/2 mice showing anxiety-related genetic defects. |
2013-06-21 |
2023-08-12 |
mouse |
M Waraczynski, W Zwifelhofer, L Kueh. Brain stimulation reward is altered by affecting dopamine-glutamate interactions in the central extended amygdala. Neuroscience. vol 224. 2013-06-17. PMID:22906479. |
this work compares the effects on brain stimulation reward (bsr) when combining d2 dopamine receptor and ampa glutamate receptor manipulations in the sublenticular central extended amygdala (sleac) and the nucleus accumbens shell (nac shell). |
2013-06-17 |
2023-08-12 |
rat |
Marisa Roberto, Nicholas W Gilpin, George R Siggin. The central amygdala and alcohol: role of γ-aminobutyric acid, glutamate, and neuropeptides. Cold Spring Harbor perspectives in medicine. vol 2. issue 12. 2013-05-10. PMID:23085848. |
the central amygdala and alcohol: role of γ-aminobutyric acid, glutamate, and neuropeptides. |
2013-05-10 |
2023-08-12 |
Not clear |
Sungmo Park, Sukwon Lee, Jeongyeon Kim, Sukwoo Cho. Ex vivo depotentiation of conditioning-induced potentiation at thalamic input synapses onto the lateral amygdala requires GluN2B-containing NMDA receptors. Neuroscience letters. vol 530. issue 2. 2013-05-09. PMID:23069667. |
we have previously characterized the ex vivo depotentiation (depotentiation(ex vivo)) of conditioning-induced synaptic potentiation at thalamic input synapses onto the lateral amygdala (t-la synapses) as a potential cellular substrate for fear extinction: both depotentiation(ex vivo) and fear extinction require nmda receptors, mitogen-activated protein kinases, metabotropic glutamate receptor 1, de novo protein synthesis and ampa receptor internalization in the amygdala. |
2013-05-09 |
2023-08-12 |
Not clear |
Marc A Beckerman, Tracey A Van Kempen, Nicholas J Justice, Teresa A Milner, Michael J Glas. Corticotropin-releasing factor in the mouse central nucleus of the amygdala: ultrastructural distribution in NMDA-NR1 receptor subunit expressing neurons as well as projection neurons to the bed nucleus of the stria terminalis. Experimental neurology. vol 239. 2013-02-28. PMID:23063907. |
central amygdala crf, acting via the crf type 1 receptor (crf-r1), plays an integral role in stress responses and emotional learning, processes that are generally known to involve functional nmda-type glutamate receptors. |
2013-02-28 |
2023-08-12 |
mouse |
Aisling O'Neill, Thomas Frod. Brain structure and function in borderline personality disorder. Brain structure & function. vol 217. issue 4. 2013-02-04. PMID:22252376. |
some suspected trends in the data are highlighted, including reductions in the hippocampi and amygdalae of bpd patients compared to healthy controls, exaggerated amygdala activity in bpd patients when confronted with emotion-related stimulus, and negative correlations between increases in left amygdalar creatine and reductions in amygdalar volume, reductions in absolute n-acetylaspartate concentration in the dorsolateral prefrontal cortex of bpd patients, and increases in glutamate concentration in the anterior cingulate cortices of bpd patients. |
2013-02-04 |
2023-08-12 |
Not clear |
V Aroniadou-Anderjaska, V I Pidoplichko, T H Figueiredo, C P Almeida-Suhett, E M Prager, M F M Brag. Presynaptic facilitation of glutamate release in the basolateral amygdala: a mechanism for the anxiogenic and seizurogenic function of GluK1 receptors. Neuroscience. vol 221. 2013-01-23. PMID:22796081. |
presynaptic facilitation of glutamate release in the basolateral amygdala: a mechanism for the anxiogenic and seizurogenic function of gluk1 receptors. |
2013-01-23 |
2023-08-12 |
rat |