| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bo-Seong Jeong, Jeong Seok Cha, Insu Hwang, Uijin Kim, Jared Adolf-Bryfogle, Brian Coventry, Hyun-Soo Cho, Kyun-Do Kim, Byung-Ha O. Computational design of a neutralizing antibody with picomolar binding affinity for all concerning SARS-CoV-2 variants. mAbs. vol 14. issue 1. 2022-01-15. PMID:35030983. |
subsequently, through experimental affinity enhancement and computational affinity maturation, it was further developed to bind the rbd of all concerning sars-cov-2 variants, sars-cov-1 and pangolin coronavirus with pico-molar binding affinities, consistently exhibited strong neutralization activity against wild-type sars-cov-2 and the alpha and delta variants. |
2022-01-15 |
2023-08-13 |
Not clear |
| Jerome Hadjadj, Delphine Planas, Amani Ouedrani, Solene Buffier, Laure Delage, Yann Nguyen, Timothée Bruel, Marie-Claude Stolzenberg, Isabelle Staropoli, Natalia Ermak, Laure Macraigne, Caroline Morbieu, Soledad Henriquez, David Veyer, Hélène Péré, Marion Casadevall, Luc Mouthon, Frederic Rieux-Laucat, Lucienne Chatenoud, Olivier Schwartz, Benjamin Terrie. Immunogenicity of BNT162b2 vaccine against the Alpha and Delta variants in immunocompromised patients with systemic inflammatory diseases. Annals of the rheumatic diseases. 2022-01-13. PMID:35022159. |
immunogenicity of bnt162b2 vaccine against the alpha and delta variants in immunocompromised patients with systemic inflammatory diseases. |
2022-01-13 |
2023-08-13 |
Not clear |
| Miray Yılmaz Çelebi, Elif Kıymet, Elif Böncüoğlu, Şahika Şahinkaya, Ela Cem, Mine Düzgöl, Aybüke Akaslan Kara, Fahri Yüce Ayhan, Süleyman Nuri Bayram, İlker Devri. Evaluation of childhood hospitalization rates and degree of severity of SARS-CoV-2 variants including of the B.1.1.7 (Alpha), B.1.315/P.1 (Beta/Gamma), and B.1.617.2 (Delta). Journal of medical virology. 2022-01-12. PMID:35018660. |
evaluation of childhood hospitalization rates and degree of severity of sars-cov-2 variants including of the b.1.1.7 (alpha), b.1.315/p.1 (beta/gamma), and b.1.617.2 (delta). |
2022-01-12 |
2023-08-13 |
Not clear |
| Miray Yılmaz Çelebi, Elif Kıymet, Elif Böncüoğlu, Şahika Şahinkaya, Ela Cem, Mine Düzgöl, Aybüke Akaslan Kara, Fahri Yüce Ayhan, Süleyman Nuri Bayram, İlker Devri. Evaluation of childhood hospitalization rates and degree of severity of SARS-CoV-2 variants including of the B.1.1.7 (Alpha), B.1.315/P.1 (Beta/Gamma), and B.1.617.2 (Delta). Journal of medical virology. 2022-01-12. PMID:35018660. |
severe acute respiratory syndrome coronavirus 2 is appearing with an increasing number of variants day by day, this study aimed to determine the effect of b.1.1.7 (alpha), b.1.351 (beta), p.1 (gamma), and b.1.617.2 (delta) variants on hospitalization rates. |
2022-01-12 |
2023-08-13 |
Not clear |
| María Eva González-Trujano, Felix Krengel, Ricardo Reyes-Chilpa, Benjamín Villasana-Salazar, José David González-Gómez, Fernando Santos-Valencia, Edgar Urbina-Trejo, Adrián Martínez, David Martínez-Varga. Tabernaemontana arborea and ibogaine induce paroxysmal EEG activity in freely moving mice: involvement of serotonin 5-HT Neurotoxicology. 2022-01-09. PMID:34999156. |
promoted a significant increase in the relative power of the delta band and a significant reduction in alpha band values, denoting a cns depressant effect. |
2022-01-09 |
2023-08-13 |
mouse |
| Jéromine Klingler, Gregory S Lambert, Vincenza Itri, Sean Liu, Juan C Bandres, Gospel Enyindah-Asonye, Xiaomei Liu, Viviana Simon, Charles R Gleason, Giulio Kleiner, Hsin-Ping Chiu, Chuan-Tien Hung, Shreyas Kowdle, Fatima Amanat, Benhur Lee, Susan Zolla-Pazner, Chitra Upadhyay, Catarina E Hio. Detection of Antibody Responses Against SARS-CoV-2 in Plasma and Saliva From Vaccinated and Infected Individuals. Frontiers in immunology. vol 12. 2022-01-06. PMID:34987505. |
neutralization titers against the initial wa1 (d614g), b.1.1.7 (alpha) and b.1.617.2 (delta) strains were similar but lower against the b.1.351 (beta) strain. |
2022-01-06 |
2023-08-13 |
Not clear |
| Lidewij W Rümke, Femke C Groenveld, Yvonne M G van Os, Patrique Praest, Anniek A N Tanja, Dorien T C M de Jong, Jori Symons, Rob Schuurman, Tessa Reinders, L Marije Hofstra, Stefan Nierkens, Steven F T Thijsen, Michiel Heron, Robert-Jan Lebbink, Jeffrey M Beekman, Monique Nijhuis, Annemarie M J Wensin. In-depth Characterization of Vaccine Breakthrough Infections With SARS-CoV-2 Among Health Care Workers in a Dutch Academic Medical Center. Open forum infectious diseases. vol 9. issue 1. 2022-01-06. PMID:34988250. |
these breakthrough infections presented with regular b.1.1.7 (alpha) and b.1.617.2 (delta) variants and high viral loads, despite normal vaccine-induced b- and t-cell immune responses detected by live virus neutralization assays and elispot. |
2022-01-06 |
2023-08-13 |
Not clear |
| Giulietta Maruggi, Corey P Mallett, Jason W Westerbeck, Tiffany Chen, Giuseppe Lofano, Kristian Friedrich, Lin Qu, Jennifer Tong Sun, Josie McAuliffe, Amey Kanitkar, Kathryn T Arrildt, Kai-Fen Wang, Ian McBee, Deborah McCoy, Rebecca Terry, Alison Rowles, Maia Araujo Abrahim, Michael A Ringenberg, Malcolm J Gains, Catherine Spickler, Xuping Xie, Jing Zou, Pei-Yong Shi, Taru Dutt, Marcela Henao-Tamayo, Izabela Ragan, Richard A Bowen, Russell Johnson, Sandra Nuti, Kate Luisi, Jeffrey B Ulmer, Ann-Muriel Steff, Rashmi Jalah, Sylvie Bertholet, Alan H Stokes, Dong Y. A self-amplifying mRNA SARS-CoV-2 vaccine candidate induces safe and robust protective immunity in preclinical models. Molecular therapy : the journal of the American Society of Gene Therapy. 2022-01-06. PMID:34990810. |
in mice, one immunization with the sam vaccine elicited a robust spike-specific antibody response, which was further boosted by a second immunization, and effectively neutralized the matched sars-cov-2 wuhan strain as well as b.1.1.7 (alpha), b.1.351 (beta) and b.1.617.2 (delta) variants. |
2022-01-06 |
2023-08-13 |
mouse |
| Dongyan Xiong, Xiaoxu Zhang, Mengjuan Shi, Nuo Wang, Ping He, Zhuo Dong, Jie Zhong, Jing Luo, Yong Wang, Junping Yu, Hongping We. Developing an Amplification Refractory Mutation System-Quantitative Reverse Transcription-PCR Assay for Rapid and Sensitive Screening of SARS-CoV-2 Variants of Concern. Microbiology spectrum. 2022-01-05. PMID:34985323. |
among them, mutations c1709a (a change of c to a at position 1709) and c56g, respectively, were found in more than 99% of the genomes of alpha and delta variants and were specific to them. |
2022-01-05 |
2023-08-13 |
Not clear |
| Dongyan Xiong, Xiaoxu Zhang, Mengjuan Shi, Nuo Wang, Ping He, Zhuo Dong, Jie Zhong, Jing Luo, Yong Wang, Junping Yu, Hongping We. Developing an Amplification Refractory Mutation System-Quantitative Reverse Transcription-PCR Assay for Rapid and Sensitive Screening of SARS-CoV-2 Variants of Concern. Microbiology spectrum. 2022-01-05. PMID:34985323. |
the assay can detect as little as 1 copy/μl of the vocs, and the results for identifying alpha and delta variants in clinical samples by the arms-rt-qpcr assay showed 100% agreement with the results using sequencing-based methods. |
2022-01-05 |
2023-08-13 |
Not clear |
| Dongyan Xiong, Xiaoxu Zhang, Mengjuan Shi, Nuo Wang, Ping He, Zhuo Dong, Jie Zhong, Jing Luo, Yong Wang, Junping Yu, Hongping We. Developing an Amplification Refractory Mutation System-Quantitative Reverse Transcription-PCR Assay for Rapid and Sensitive Screening of SARS-CoV-2 Variants of Concern. Microbiology spectrum. 2022-01-05. PMID:34985323. |
therefore, the arms-rt-qpcr assay could be used for screening the two highly concerning variants alpha and delta by normal pcr laboratories in airports and in hospitals and other health-related organizations. |
2022-01-05 |
2023-08-13 |
Not clear |
| David W Eyre, Donald Taylor, Mark Purver, David Chapman, Tom Fowler, Koen B Pouwels, A Sarah Walker, Tim E A Pet. Effect of Covid-19 Vaccination on Transmission of Alpha and Delta Variants. The New England journal of medicine. 2022-01-05. PMID:34986294. |
effect of covid-19 vaccination on transmission of alpha and delta variants. |
2022-01-05 |
2023-08-13 |
Not clear |
| Paul Elliott, David Haw, Haowei Wang, Oliver Eales, Caroline E Walters, Kylie E C Ainslie, Christina Atchison, Claudio Fronterre, Peter J Diggle, Andrew J Page, Alexander J Trotter, Sophie J Prosolek, Deborah Ashby, Christl A Donnelly, Wendy Barclay, Graham Taylor, Graham Cooke, Helen Ward, Ara Darzi, Steven Rile. Exponential growth, high prevalence of SARS-CoV-2, and vaccine effectiveness associated with the Delta variant. Science (New York, N.Y.). vol 374. issue 6574. 2021-12-30. PMID:34726481. |
during june and july 2021, we observed sustained exponential growth with an average doubling time of 25 days, driven by complete replacement of the alpha variant by delta and by high prevalence at younger, less-vaccinated ages. |
2021-12-30 |
2024-01-07 |
Not clear |
| Lynnette M Mason, Robert J Barry, Adam R Clark. Age-related changes in the EEG in an eyes-open condition: I. Normal development. International journal of psychophysiology : official journal of the International Organization of Psychophysiology. 2021-12-29. PMID:34963633. |
the eeg was recorded during an eyes-open resting condition and fourier transformed to provide estimates for total power, and absolute and relative power in the delta, theta, alpha and beta bands. |
2021-12-29 |
2023-08-13 |
Not clear |
| Lynnette M Mason, Robert J Barry, Adam R Clark. Age-related changes in the EEG in an eyes-open condition: I. Normal development. International journal of psychophysiology : official journal of the International Organization of Psychophysiology. 2021-12-29. PMID:34963633. |
total power and absolute delta, theta, alpha, and beta decreased with increasing age, as did relative delta, while relative alpha increased with increasing age. |
2021-12-29 |
2023-08-13 |
Not clear |
| Tatjana Vilibic-Cavlek, Vladimir Stevanovic, Diana Brlek-Gorski, Ivana Ferencak, Thomas Ferenc, Magdalena Ujevic-Bosnjak, Irena Tabain, Natasa Janev-Holcer, Ivana Perkovic, Mario Anticevic, Barbara Bekavac, Bernard Kaic, Anna Mrzljak, Marin Ganjto, Ljiljana Zmak, Maja Mauric Maljkovic, Pavle Jelicic, Lovro Bucic, Ljubo Barbi. Emerging Trends in the Epidemiology of COVID-19: The Croatian 'One Health' Perspective. Viruses. vol 13. issue 12. 2021-12-28. PMID:34960623. |
the alpha variant, dominant from march 2021 (>50% of positive samples), was rapidly replaced by delta variants (>90%) by august 2021. |
2021-12-28 |
2023-08-13 |
Not clear |
| Rosa Costa, Beatriz Olea, María Alma Bracho, Eliseo Albert, Paula de Michelena, Cecilia Martínez-Costa, Fernando González-Candelas, David Navarr. RNA viral loads of SARS-CoV-2 Alpha and Delta variants in nasopharyngeal specimens at diagnosis stratified by age, clinical presentation and vaccination status. The Journal of infection. 2021-12-26. PMID:34953901. |
rna viral loads of sars-cov-2 alpha and delta variants in nasopharyngeal specimens at diagnosis stratified by age, clinical presentation and vaccination status. |
2021-12-26 |
2023-08-13 |
Not clear |
| Hideyuki Iwanaga, Takefumi Ueno, Naoya Oribe, Manabu Hashimoto, Jun Nishimura, Naho Nakayama, Nami Haraguchi, Hiroshi Tateishi, Yutaka Kunitake, Yoshito Mizoguchi, Akira Monj. Correlation between Post-Acute Electroconvulsive Therapy Alpha-Band Spectrum Power Increase and Improvement of Psychiatric Symptoms. Journal of personalized medicine. vol 11. issue 12. 2021-12-24. PMID:34945787. |
the spectral power increased significantly after ect in the delta, theta, and alpha bands. |
2021-12-24 |
2023-08-13 |
Not clear |
| Bing Hu, Minbo Xu, Luyao Zhu, Jiahui Lin, Zhizhi Wang, Dingjiang Wang, Dongmei Zhan. A bidirectional Hopf bifurcation analysis of Parkinson's oscillation in a simplified basal ganglia model. Journal of theoretical biology. 2021-12-23. PMID:34942160. |
the hopf1 and hopf2 bifurcations both show that when the state transfers from the stable region to the oscillation region, oscillatory activities always originate from the beta frequency band, and then gradually evolve into the alpha frequency band, the theta frequency band and delta frequency band in this model. |
2021-12-23 |
2023-08-13 |
Not clear |
| David Goldblatt, Andrew Fiore-Gartland, Marina Johnson, Adam Hunt, Christopher Bengt, Dace Zavadska, Hilda Darta Snipe, Jeremy S Brown, Lesley Workman, Heather J Zar, David Montefiori, Xiaoying Shen, Peter Dull, Stanley Plotkin, George Siber, Donna Ambrosin. Towards a population-based threshold of protection for COVID-19 vaccines. Vaccine. 2021-12-22. PMID:34933765. |
igg anti-spike antibodies were highly correlated with id50 neutralization in a validated pseudoviral assay and correlated significantly with efficacies for protection against infection with wild-type, alpha and delta variant sars-cov-2 virus. |
2021-12-22 |
2023-08-13 |
Not clear |