| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C M Komar, O Braissant, W Wahli, T E Curr. Expression and localization of PPARs in the rat ovary during follicular development and the periovulatory period. Endocrinology. vol 142. issue 11. 2001-12-04. PMID:11606451. |
the more general and steady expression of ppars alpha and delta indicate that they may play a role in basal ovarian function. |
2001-12-04 |
2023-08-12 |
human |
| M Krauss, W Wilck. Predicting soil-water partitioning of polycyclic aromatic hydrocarbons and polychlorinated biphenyls by desorption with methanol-water mixtures at different temperatures. Environmental science & technology. vol 35. issue 11. 2001-11-01. PMID:11414039. |
the calculated alpha and delta hdes of individual compounds varied considerably among the soils (coefficients of variation 5-20% and 20-30%, respectively), alpha increased with increasing hydrophobicity of the compounds. |
2001-11-01 |
2023-08-12 |
Not clear |
| M Krauss, W Wilck. Predicting soil-water partitioning of polycyclic aromatic hydrocarbons and polychlorinated biphenyls by desorption with methanol-water mixtures at different temperatures. Environmental science & technology. vol 35. issue 11. 2001-11-01. PMID:11414039. |
the use of less temperature/methanol fraction combinations requires a suitable estimation of alpha and delta hdes, as their choice may change the obtained koc values by up to a factor of 10. |
2001-11-01 |
2023-08-12 |
Not clear |
| C Son, K Hosoda, J Matsuda, J Fujikura, S Yonemitsu, H Iwakura, H Masuzaki, Y Ogawa, T Hayashi, H Itoh, H Nishimura, G Inoue, Y Yoshimasa, Y Yamori, K Naka. Up-regulation of uncoupling protein 3 gene expression by fatty acids and agonists for PPARs in L6 myotubes. Endocrinology. vol 142. issue 10. 2001-11-01. PMID:11564673. |
l-165041, a ppar delta agonist, increased ucp3 gene expression in l6 myotubes, whereas neither wy 14,643, a ppar alpha agonist, nor pioglitazone, a ppar gamma agonist, increased it. |
2001-11-01 |
2023-08-12 |
Not clear |
| A Tarrade, K Schoonjans, J Guibourdenche, J M Bidart, M Vidaud, J Auwerx, C Rochette-Egly, D Evain-Brio. PPAR gamma/RXR alpha heterodimers are involved in human CG beta synthesis and human trophoblast differentiation. Endocrinology. vol 142. issue 10. 2001-11-01. PMID:11564716. |
moreover, specific ligands for rxrs or ppar gamma (but not for ppar alpha or ppar delta) increase both human cg beta transcript levels and the secretion of human cg and its free beta-subunit. |
2001-11-01 |
2023-08-12 |
mouse |
| S Yoshii, M Tanaka, Y Otsuki, T Fujiyama, H Kataoka, H Arai, H Hanai, H Sugimur. Involvement of alpha-PAK-interacting exchange factor in the PAK1-c-Jun NH(2)-terminal kinase 1 activation and apoptosis induced by benzo[a]pyrene. Molecular and cellular biology. vol 21. issue 20. 2001-11-01. PMID:11564864. |
moreover, alpha-pak-interacting exchange factor (alpha pix) mrna and its protein expression were upregulated by b(a)p. while overexpression of an active mutant of alpha pix (deltach) facilitated b(a)p-induced activation of cdc42/rac1, pak1, and jnk1, overexpression of mutated alphapix (l383r, l384s), which lacks guanine nucleotide exchange factor activity, sh3 domain-deleted alphapix (delta sh3), which lacks the ability to bind pak, kinase-negative pak1 (k299r), and kinase-negative sek1 (k220a, k224l) inhibited b(a)p-triggered jnk1 activation. |
2001-11-01 |
2023-08-12 |
Not clear |
| M Shanmugam, N L Krett, E T Maizels, F M Murad, S T Rosen, M Hunzicker-Dun. A role for protein kinase C delta in the differential sensitivity of MCF-7 and MDA-MB 231 human breast cancer cells to phorbol ester-induced growth arrest and p21(WAFI/CIP1) induction. Cancer letters. vol 172. issue 1. 2001-11-01. PMID:11595128. |
direct evidence to support this hypothesis was provided by the ability of transient transfections into mcf-7 cells of constitutively active pkc delta but not of pkc's eta or alpha or epsilon to enhance p21(wafl/cip1) promoter activity. |
2001-11-01 |
2023-08-12 |
human |
| F Kullmann, S Hollerbach, G Lock, A Holstege, T Dierks, J Schölmeric. Brain electrical activity mapping of EEG for the diagnosis of (sub)clinical hepatic encephalopathy in chronic liver disease. European journal of gastroenterology & hepatology. vol 13. issue 5. 2001-10-25. PMID:11396530. |
mean amplitudes and their topographic localization in the following frequency-bands were analysed: delta (1.0-3.5 hz), theta (4.0-7.5 hz), alpha 1 (8.0-9.5 hz), alpha 2 (10.0-11.5 hz), beta 1 (12.0-15.5 hz), beta 2 (16.0-19.5 hz), and beta 3 (20.0-23.5 hz). |
2001-10-25 |
2023-08-12 |
Not clear |
| M W Bergmann, P Loser, R Dietz, R von Harsdor. Effect of NF-kappa B Inhibition on TNF-alpha-induced apoptosis and downstream pathways in cardiomyocytes. Journal of molecular and cellular cardiology. vol 33. issue 6. 2001-10-25. PMID:11444925. |
addition of proteasome inhibitor mg132 or adenoviral expression of a truncated i kappa b alpha (i kappa b delta n) inhibited tnf-alpha-induced nf-kappa b nuclear translocation in a dose-dependent manner. |
2001-10-25 |
2023-08-12 |
mouse |
| M W Bergmann, P Loser, R Dietz, R von Harsdor. Effect of NF-kappa B Inhibition on TNF-alpha-induced apoptosis and downstream pathways in cardiomyocytes. Journal of molecular and cellular cardiology. vol 33. issue 6. 2001-10-25. PMID:11444925. |
however, specific inhibition of nf-kappa b activation by ad5-i kappa b alpha delta n (moi=50) or mg132 (5 microm) increased apoptosis as measured by subg1-assay (h9c2 cells) and annexin v binding/propidium iodide (neonatal cardiomyocytes, facs-analysis: 7+/-2% to 26+/-5% annexin v positive/pi negative), respectively. |
2001-10-25 |
2023-08-12 |
mouse |
| M W Bergmann, P Loser, R Dietz, R von Harsdor. Effect of NF-kappa B Inhibition on TNF-alpha-induced apoptosis and downstream pathways in cardiomyocytes. Journal of molecular and cellular cardiology. vol 33. issue 6. 2001-10-25. PMID:11444925. |
furthermore, caspase-3 activation was increased by 52+/-7% in neonatal cardiomyocytes after tnf alpha+ad5-i kappa b alpha delta n compared to tnf alpha+ad5-control treatment. |
2001-10-25 |
2023-08-12 |
mouse |
| M Gallagher, P Obeïd, P N Marche, E Jouvin-March. Both TCR alpha and TCR delta chain diversity are regulated during thymic ontogeny. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 3. 2001-10-25. PMID:11466364. |
both tcr alpha and tcr delta chain diversity are regulated during thymic ontogeny. |
2001-10-25 |
2023-08-12 |
Not clear |
| J L Carre, J H Abalain, L L Sarlieve, H H Floc. Ontogeny of steroid metabolizing enzymes in rat oligodendrocytes. The Journal of steroid biochemistry and molecular biology. vol 78. issue 1. 2001-10-25. PMID:11530289. |
the main activities were 5 alpha reduction of testosterone and progesterone and 3 beta hydroxy steroid dehydrogenase-isomerase which transformed pregnenolone into progesterone and dhea into delta 4 androstenedione. |
2001-10-25 |
2023-08-12 |
rat |
| A J Tiltman, H Al. Distribution of alpha glutathione S-transferase in ovarian neoplasms: an immunohistochemical study. Histopathology. vol 39. issue 3. 2001-10-25. PMID:11532037. |
alpha glutathione s-transferase (alpha-gst) has been shown to be an immunohistochemical marker for delta(4-5) isomerase, an enzyme active in steroidogenesis. |
2001-10-25 |
2023-08-12 |
Not clear |
| A Izcue, G Morales, S Minguet, A Sánchez-Movilla, P Morales, J A Martínez-M, M L Gaspar, M A Marco. Both B and gammadelta TCR(+) lymphocytes regulate alphabeta TCR(+) lymphocytes involved in superantigen specific responses. European journal of immunology. vol 31. issue 9. 2001-10-25. PMID:11536180. |
the role of both b and gamma delta t cells on the regulation of these sag-specific alpha beta t cell responses was addressed in ia(b+)ie(b-) c57bl/6 mice bearing genetically induced b cell and gamma delta t cell deficiencies. |
2001-10-25 |
2023-08-12 |
mouse |
| A Izcue, G Morales, S Minguet, A Sánchez-Movilla, P Morales, J A Martínez-M, M L Gaspar, M A Marco. Both B and gammadelta TCR(+) lymphocytes regulate alphabeta TCR(+) lymphocytes involved in superantigen specific responses. European journal of immunology. vol 31. issue 9. 2001-10-25. PMID:11536180. |
in contrast, gamma delta t cells positively stimulated the utilization of the same sag-responsive alpha beta t cell subsets. |
2001-10-25 |
2023-08-12 |
mouse |
| G A Herin, S Du, E Aizenma. The neuroprotective agent ebselen modifies NMDA receptor function via the redox modulatory site. Journal of neurochemistry. vol 78. issue 6. 2001-10-25. PMID:11579139. |
ebselen also reversed dtt block of carbachol-mediated currents in cos-7 cells expressing the alpha(2)beta delta epsilon subunits of the acetylcholine receptor, an additional redox-sensitive ion channel. |
2001-10-25 |
2023-08-12 |
Not clear |
| M G Kang, C C Chen, R Felix, V A Letts, W N Frankel, Y Mori, K P Campbel. Biochemical and biophysical evidence for gamma 2 subunit association with neuronal voltage-activated Ca2+ channels. The Journal of biological chemistry. vol 276. issue 35. 2001-10-18. PMID:11441000. |
electrophysiological analyses showed that gamma(2) co-expression caused a significant decrease in the current amplitude of both alpha(1b)(alpha(1)2.2)-class (36.8%) and alpha(1a)(alpha(1)2.1)-class (39.7%) ca(2+) channels (alpha(1)beta(3)alpha(2)delta). |
2001-10-18 |
2023-08-12 |
mouse |
| M G Kang, C C Chen, R Felix, V A Letts, W N Frankel, Y Mori, K P Campbel. Biochemical and biophysical evidence for gamma 2 subunit association with neuronal voltage-activated Ca2+ channels. The Journal of biological chemistry. vol 276. issue 35. 2001-10-18. PMID:11441000. |
interestingly, the inhibitory effects of the gamma(2) subunit on current amplitude were dependent on the co-expression of the alpha(2)delta subunit. |
2001-10-18 |
2023-08-12 |
mouse |
| M G Kang, C C Chen, R Felix, V A Letts, W N Frankel, Y Mori, K P Campbel. Biochemical and biophysical evidence for gamma 2 subunit association with neuronal voltage-activated Ca2+ channels. The Journal of biological chemistry. vol 276. issue 35. 2001-10-18. PMID:11441000. |
furthermore, the gamma(2) subunit likely contributes to the fine-tuning of neuronal ca(2+) channels by counterbalancing the effects of the alpha(2)delta subunit. |
2001-10-18 |
2023-08-12 |
mouse |