| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Francesco Forconi, Surinder S Sahota, Donatella Raspadori, Micaela Ippoliti, Gavin Babbage, Francesco Lauria, Freda K Stevenso. Hairy cell leukemia: at the crossroad of somatic mutation and isotype switch. Blood. vol 104. issue 10. 2004-12-23. PMID:15284115. |
multiple tumor-derived variable-(diversity)-joining-constant mu delta, gamma, alpha (v(d)j-cmu, delta, gamma, alpha) transcripts were confirmed in single cells of a further case. |
2004-12-23 |
2023-08-12 |
Not clear |
| Nadia Rucci, Enrico Ricevuto, Corrado Ficorella, Maurizio Longo, Marie Perez, Claudia Di Giacinto, Alessia Funari, Anna Teti, Silvia Migliacci. In vivo bone metastases, osteoclastogenic ability, and phenotypic characterization of human breast cancer cells. Bone. vol 34. issue 4. 2004-12-22. PMID:15050901. |
mcf-7adr also showed significantly higher levels of the protein kinase c (pkc) alpha and beta2 and a selective activation of pkc compared to mcf-7, where the most abundant isoforms were beta1 and delta. |
2004-12-22 |
2023-08-12 |
mouse |
| Tao Hu, Brian A Stearns, Brian T Campbell, Jeannie M Arruda, Chixu Chen, Jayashree Aiyar, Robert E Bezverkov, Angelina Santini, Hervé Schaffhauser, Wensheng Liu, Shankar Venkatraman, Benito Muno. Synthesis and biological evaluation of 6-aryl-6H-pyrrolo[3,4-d]pyridazine derivatives as high-affinity ligands of the alpha(2)delta subunit of voltage-gated calcium channels. Bioorganic & medicinal chemistry letters. vol 14. issue 9. 2004-12-22. PMID:15080973. |
synthesis and biological evaluation of 6-aryl-6h-pyrrolo[3,4-d]pyridazine derivatives as high-affinity ligands of the alpha(2)delta subunit of voltage-gated calcium channels. |
2004-12-22 |
2023-08-12 |
Not clear |
| Tao Hu, Brian A Stearns, Brian T Campbell, Jeannie M Arruda, Chixu Chen, Jayashree Aiyar, Robert E Bezverkov, Angelina Santini, Hervé Schaffhauser, Wensheng Liu, Shankar Venkatraman, Benito Muno. Synthesis and biological evaluation of 6-aryl-6H-pyrrolo[3,4-d]pyridazine derivatives as high-affinity ligands of the alpha(2)delta subunit of voltage-gated calcium channels. Bioorganic & medicinal chemistry letters. vol 14. issue 9. 2004-12-22. PMID:15080973. |
a novel class of 2h-pyrrolo[3,4-c]pyridazine ligands of the alpha (2) delta subunit of voltage-gated calcium channels is described. |
2004-12-22 |
2023-08-12 |
Not clear |
| Tao Hu, Brian A Stearns, Brian T Campbell, Jeannie M Arruda, Chixu Chen, Jayashree Aiyar, Robert E Bezverkov, Angelina Santini, Hervé Schaffhauser, Wensheng Liu, Shankar Venkatraman, Benito Muno. Synthesis and biological evaluation of 6-aryl-6H-pyrrolo[3,4-d]pyridazine derivatives as high-affinity ligands of the alpha(2)delta subunit of voltage-gated calcium channels. Bioorganic & medicinal chemistry letters. vol 14. issue 9. 2004-12-22. PMID:15080973. |
compound 4a with high affinity toward alpha (2) delta was identified through structure-activity relationship studies of the lead compound. |
2004-12-22 |
2023-08-12 |
Not clear |
| Tao Hu, Brian A Stearns, Brian T Campbell, Jeannie M Arruda, Chixu Chen, Jayashree Aiyar, Robert E Bezverkov, Angelina Santini, Hervé Schaffhauser, Wensheng Liu, Shankar Venkatraman, Benito Muno. Synthesis and biological evaluation of 6-aryl-6H-pyrrolo[3,4-d]pyridazine derivatives as high-affinity ligands of the alpha(2)delta subunit of voltage-gated calcium channels. Bioorganic & medicinal chemistry letters. vol 14. issue 9. 2004-12-22. PMID:15080973. |
tritiated ligand [(3)h]-4b was synthesized to demonstrate that this ligand binds to the same site as gabapentin toward alpha (2) delta subunit of voltage-gated calcium channels. |
2004-12-22 |
2023-08-12 |
Not clear |
| J B Dahl, O Mathiesen, S Møinich. 'Protective premedication': an option with gabapentin and related drugs? A review of gabapentin and pregabalin in in the treatment of post-operative pain. Acta anaesthesiologica Scandinavica. vol 48. issue 9. 2004-12-22. PMID:15352959. |
gabapentin, which binds to the alpha(2)delta subunit of the voltage-dependent calcium channel, is active in animal models of 'pathological' but not in models of 'physiological' pain. |
2004-12-22 |
2023-08-12 |
Not clear |
| Marsha R Haynes, Gillian E W. Evolution of the variable gene segments and recombination signal sequences of the human T-cell receptor alpha/delta locus. Immunogenetics. vol 56. issue 7. 2004-12-21. PMID:15378298. |
the t-cell receptor (tcr) alpha and delta loci are particularly interesting because of their unique genomic structure, in that the gene segments for each locus are interspersed. |
2004-12-21 |
2023-08-12 |
human |
| Marsha R Haynes, Gillian E W. Evolution of the variable gene segments and recombination signal sequences of the human T-cell receptor alpha/delta locus. Immunogenetics. vol 56. issue 7. 2004-12-21. PMID:15378298. |
our phylogenetic analyses divided the alpha and delta variable gene segments into two major groups each with distinguishing motifs in both the framework and complementarity determining regions (cdrs). |
2004-12-21 |
2023-08-12 |
human |
| Lynnette Phillips McCluske. Up-regulation of activated macrophages in response to degeneration in the taste system: effects of dietary sodium restriction. The Journal of comparative neurology. vol 479. issue 1. 2004-12-21. PMID:15389612. |
at day 1, 2, 5, 7, or 50 postsectioning, immunostaining was used to detect the percentage of staining for activated macrophages, the number of alpha beta t cells, and the number of delta gamma epithelial t cells in the tongue. |
2004-12-21 |
2023-08-12 |
rat |
| Xavier López, Josep M Poble. DFT study on the five isomers of PW(12)O(40)(3)(-): relative stabilization upon reduction. Inorganic chemistry. vol 43. issue 22. 2004-12-16. PMID:15500315. |
the energy scale fits the experimental findings as well as the number of rotated triads of the metal-oxide core since the energy grows as follows: alpha < beta < gamma < delta < epsilon. |
2004-12-16 |
2023-08-12 |
Not clear |
| Xavier López, Josep M Poble. DFT study on the five isomers of PW(12)O(40)(3)(-): relative stabilization upon reduction. Inorganic chemistry. vol 43. issue 22. 2004-12-16. PMID:15500315. |
the other isomers, delta and epsilon, are much more unstable than alpha or beta in any reduction state. |
2004-12-16 |
2023-08-12 |
Not clear |
| M Rihl, J Gu, D Baeten, E Märker-Hermann, J C Goodall, J S H Gaston, J G Kuipers, H Zeidler, D T Y Y. Alpha beta but not gamma delta T cell clones in synovial fluids of patients with reactive arthritis show active transcription of tumour necrosis factor alpha and interferon gamma. Annals of the rheumatic diseases. vol 63. issue 12. 2004-12-16. PMID:15547094. |
alpha beta but not gamma delta t cell clones in synovial fluids of patients with reactive arthritis show active transcription of tumour necrosis factor alpha and interferon gamma. |
2004-12-16 |
2023-08-12 |
Not clear |
| P W Hoban, M Heydarian, W A Beckham, A H Beddo. Dose rate dependence of a PTW diamond detector in the dosimetry of a 6 MV photon beam. Physics in medicine and biology. vol 39. issue 8. 2004-12-15. PMID:15551563. |
as dose rate is varied by changing fsd or depth (changing dose per pulse), detector current and dose rate are related by the expression i alpha ddelta where delta is approximately 0.98. |
2004-12-15 |
2023-08-12 |
Not clear |
| D P Lu, V Chandrakanthan, A Cahana, S Ishii, C O'Neil. Trophic signals acting via phosphatidylinositol-3 kinase are required for normal pre-implantation mouse embryo development. Journal of cell science. vol 117. issue Pt 8. 2004-12-10. PMID:15020683. |
the two-cell embryo expressed 1-o-phosphatidylinositol 3-kinase catalytic subunits p110 alpha, beta, gamma and delta, and regulatory subunits p85 alpha and beta. |
2004-12-10 |
2023-08-12 |
mouse |
| Nejmi Dilmac, Nathan Hilliard, Gregory H Hockerma. Molecular determinants of frequency dependence and Ca2+ potentiation of verapamil block in the pore region of Cav1.2. Molecular pharmacology. vol 66. issue 5. 2004-12-06. PMID:15286207. |
mutant and wild-type ca(v)1.2 channels were transiently expressed in tsa 201 cells with beta(1b) and alpha(2)delta subunits. |
2004-12-06 |
2023-08-12 |
Not clear |
| Alexandre Fredenrich, Paul A Grimald. Roles of peroxisome proliferator-activated receptor delta in skeletal muscle function and adaptation. Current opinion in clinical nutrition and metabolic care. vol 7. issue 4. 2004-12-02. PMID:15192438. |
the roles of peroxisome proliferator-activated receptor alpha and gamma isotypes have been well established, while the functions of the third member of the family, peroxisome proliferator-activated receptor delta, remained unclear until very recently. |
2004-12-02 |
2023-08-12 |
Not clear |
| Masataka Kudo, Akira Sugawara, Akira Uruno, Kazuhisa Takeuchi, Sadayoshi It. Transcription suppression of peroxisome proliferator-activated receptor gamma2 gene expression by tumor necrosis factor alpha via an inhibition of CCAAT/ enhancer-binding protein delta during the early stage of adipocyte differentiation. Endocrinology. vol 145. issue 11. 2004-11-30. PMID:15284209. |
transcription suppression of peroxisome proliferator-activated receptor gamma2 gene expression by tumor necrosis factor alpha via an inhibition of ccaat/ enhancer-binding protein delta during the early stage of adipocyte differentiation. |
2004-11-30 |
2023-08-12 |
mouse |
| Takahiro Yasuda, Richard J Lewis, David J Adam. Overexpressed Ca(v)beta3 inhibits N-type (Cav2.2) calcium channel currents through a hyperpolarizing shift of ultra-slow and closed-state inactivation. The Journal of general physiology. vol 123. issue 4. 2004-11-19. PMID:15024042. |
at a hp of -80 mv, coinjection of various concentrations (0-12.5 ng) of the beta3 with ca(v)2.2alpha(1) and alpha(2)delta enhanced the maximum conductance of expressed channels at lower beta3 concentrations but at higher concentrations (>2.5 ng/cell) caused a marked inhibition. |
2004-11-19 |
2023-08-12 |
xenopus_laevis |
| Warren S Pear, LiLi Tu, Paul L Stei. Lineage choices in the developing thymus: choosing the T and NKT pathways. Current opinion in immunology. vol 16. issue 2. 2004-11-16. PMID:15023409. |
thymic development proceeds through several defined stages that generate not only alpha beta and gamma delta t cells but can produce dendritic cells and b cells. |
2004-11-16 |
2023-08-12 |
Not clear |