| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Fusa, I Takahashi, S Watanabe, Y Aono, H Ikeda, T Saigusa, H Nagase, T Suzuki, N Koshikawa, A R Cool. The non-peptidic delta opioid receptor agonist TAN-67 enhances dopamine efflux in the nucleus accumbens of freely moving rats via a mechanism that involves both glutamate and free radicals. Neuroscience. vol 130. issue 3. 2005-03-01. PMID:15590157. |
(+/-)-tan-67 (2-methyl-4a(alpha)-(3-hydroxyphenyl)-1,2,3,4,4a,5,12,12a(alpha)-octahydro-quinolino[2,3,3,-g]isoquinoline) is a centrally acting non-peptidic delta opioid receptor agent which has recently become available. |
2005-03-01 |
2023-08-12 |
mouse |
| Povl Krogsgaard-Larsen, Bente Frølund, Tommy Liljefors, Bjarke Eber. GABA(A) agonists and partial agonists: THIP (Gaboxadol) as a non-opioid analgesic and a novel type of hypnotic. Biochemical pharmacology. vol 68. issue 8. 2005-02-22. PMID:15451401. |
the pharmacological and clinical activities of thip probably reflect its potent effects at extrasynaptic gaba(a) receptors insensitive to benzodiazepines and containing alpha(4)beta(3)delta subunits. |
2005-02-22 |
2023-08-12 |
human |
| Xin-Ming Shen, Kinji Ohno, Steven M Sine, Andrew G Enge. Subunit-specific contribution to agonist binding and channel gating revealed by inherited mutation in muscle acetylcholine receptor M3-M4 linker. Brain : a journal of neurology. vol 128. issue Pt 2. 2005-02-22. PMID:15615813. |
to determine whether the consequences of epsilonn346del are subunit-specific, we deleted residues that align with epsilonn436 in beta, delta and alpha subunits. |
2005-02-22 |
2023-08-12 |
Not clear |
| Xin-Ming Shen, Kinji Ohno, Steven M Sine, Andrew G Enge. Subunit-specific contribution to agonist binding and channel gating revealed by inherited mutation in muscle acetylcholine receptor M3-M4 linker. Brain : a journal of neurology. vol 128. issue Pt 2. 2005-02-22. PMID:15615813. |
each deletion mutant reduces achr expression, but whereas the beta and delta mutants curtail channel open duration, the alpha mutant strikingly prolongs open duration. |
2005-02-22 |
2023-08-12 |
Not clear |
| V Rodionov, H Sohme. The contribution of the time locking of EEG waves to the generation of the auditory P300. Journal of basic and clinical physiology and pharmacology. vol 15. issue 1-2. 2005-02-17. PMID:15485131. |
to study the time locking of the 'natural' (delta, theta, slow alpha, fast alpha and beta) eeg waves during the generation of the p300 in passive (p300a) and active (p300b) auditory oddball paradigms in order to obtain insights into the generation of the p300 and into the transitions between background and evoked activity. |
2005-02-17 |
2023-08-12 |
Not clear |
| Barbara Królak-Olejnik, Bogdan Mazu. [Evaluation of CD3+/TCR-alpha-beta and CD3+/TCR-gamma-delta lymphocytes in umbilical cord blood]. Medycyna wieku rozwojowego. vol 7. issue 3 Suppl 1. 2005-02-17. PMID:15537282. |
the aim of the study was to determine the relative and absolute numbers of cd3+/tcr alpha beta and cd3+/tcr gamma delta lymphocytes in the umbilical blood. |
2005-02-17 |
2023-08-12 |
Not clear |
| Barbara Królak-Olejnik, Bogdan Mazu. [Evaluation of CD3+/TCR-alpha-beta and CD3+/TCR-gamma-delta lymphocytes in umbilical cord blood]. Medycyna wieku rozwojowego. vol 7. issue 3 Suppl 1. 2005-02-17. PMID:15537282. |
the immunophenotyping analysis was performed using an facscan flow cytometer and anti- tcr alpha beta, anti- tcr gamma delta monoclonal antibodies (becton dickinson). |
2005-02-17 |
2023-08-12 |
Not clear |
| Ruksana Huda, Leoncio A Vergara, Daneshvari R Solanki, Edward R Sherwood, Mali Mathr. Selective activation of protein kinase C delta in human neutrophils following ischemia reperfusion of skeletal muscle. Shock (Augusta, Ga.). vol 21. issue 6. 2005-02-15. PMID:15167677. |
we found that i/r rapidly activates and translocates pkc delta, but not any of the classical forms of pkc (alpha or beta) from cytosol to the particulate fraction of neutrophils. |
2005-02-15 |
2023-08-12 |
human |
| Arati S Kreibich, Julie A Blend. cAMP response element-binding protein is required for stress but not cocaine-induced reinstatement. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 30. 2005-02-15. PMID:15282271. |
furthermore, to determine whether these alterations of creb are necessary in fs or cocaine-induced reinstatement, we examined the effect of these stimuli on reinstatement behavior in mice deficient in alpha and delta isoforms of creb. |
2005-02-15 |
2023-08-12 |
mouse |
| José Maltez, Lars Hyllienmark, Vadim V Nikulin, Tom Brisma. Time course and variability of power in different frequency bands of EEG during resting conditions. Neurophysiologie clinique = Clinical neurophysiology. vol 34. issue 5. 2005-02-15. PMID:15639128. |
towards the end of the recording there was a decrease in the alpha and beta power and an increase in the delta and theta power. |
2005-02-15 |
2023-08-12 |
human |
| José Maltez, Lars Hyllienmark, Vadim V Nikulin, Tom Brisma. Time course and variability of power in different frequency bands of EEG during resting conditions. Neurophysiologie clinique = Clinical neurophysiology. vol 34. issue 5. 2005-02-15. PMID:15639128. |
the coefficient of variation (cv) for the power of 4 s epochs was in the range 0.49-0.67 (delta), 0.53-0.58 (theta), 0.58-0.76 (alpha), 0.37-0.49 (beta) and 0.09-0.12 for the alpha peak frequency. |
2005-02-15 |
2023-08-12 |
human |
| José Maltez, Lars Hyllienmark, Vadim V Nikulin, Tom Brisma. Time course and variability of power in different frequency bands of EEG during resting conditions. Neurophysiologie clinique = Clinical neurophysiology. vol 34. issue 5. 2005-02-15. PMID:15639128. |
increasing the recording length from 40 to 400 s increased cv by 36% (alpha), 41% (beta), 29% (delta) and 35% (theta), while the standard error of the mean decreased by 55-60%. |
2005-02-15 |
2023-08-12 |
human |
| Jean-Loup Bertaux, François Leblanc, Séverine Perrier, E Quemerais, Oleg Korablev, E Dimarellis, A Reberac, F Forget, P C Simon, S A Stern, Bill Sande. Nightglow in the upper atmosphere of Mars and implications for atmospheric transport. Science (New York, N.Y.). vol 307. issue 5709. 2005-02-14. PMID:15681381. |
the uv spectrum of this nightglow is composed of hydrogen lyman alpha emission (121.6 nanometers) and the gamma and delta bands of nitric oxide (no) (190 to 270 nanometers) produced when n and o atoms combine to produce the no molecule. |
2005-02-14 |
2023-08-12 |
Not clear |
| Sheryl S Smith, Yevgeniy Ruderman, Qi Hua Gong, Maria Gulinell. Effects of a low dose of ethanol in an animal model of premenstrual anxiety. Alcohol (Fayetteville, N.Y.). vol 33. issue 1. 2005-02-11. PMID:15353172. |
low (1 mm), but not 10 mm, concentrations of ethanol selectively potentiate current gated by alpha(4)beta(2)delta subunit combinations of the gamma-aminobutyric acid type a (gaba(a)) receptor, a subtype increased in hippocampus after withdrawal from progesterone in a rodent model of premenstrual anxiety. |
2005-02-11 |
2023-08-12 |
rat |
| Sheryl S Smith, Yevgeniy Ruderman, Qi Hua Gong, Maria Gulinell. Effects of a low dose of ethanol in an animal model of premenstrual anxiety. Alcohol (Fayetteville, N.Y.). vol 33. issue 1. 2005-02-11. PMID:15353172. |
however, higher doses of ethanol (0.8-1.2 g/kg) were ineffective in these animals, resulting in an "inverted u" ethanol dose effect similar to that observed at recombinant alpha(4)beta(2)delta subunit combinations of the gaba(a) receptor. |
2005-02-11 |
2023-08-12 |
rat |
| Myreille D'Astous, Marc Morissette, Thérèse Di Paol. Effect of estrogen receptor agonists treatment in MPTP mice: evidence of neuroprotection by an ER alpha agonist. Neuropharmacology. vol 47. issue 8. 2005-02-10. PMID:15567427. |
the agonists specific for each subtype were 4,4',4''-(4-propyl-[1h]-pyrazole-1,3,5-triyl)tris-phenol (ppt) (er alpha agonist), 2,3-bis(4-hydroxyphenyl)-propionitrile (dpn) and delta 3-diol (5-androsten-3 beta, 17 beta-diol, also known as 5-androstenediol, androstenediol or hermaphrodiol) (er beta agonists). |
2005-02-10 |
2023-08-12 |
mouse |
| Hiroyuki Miyach. [Design and synthesis of subtype- and species-selective peroxisome proliferator-activated receptor (PPAR) alpha ligands]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 124. issue 11. 2005-02-09. PMID:15516807. |
the molecular pharmacological discovery of the nuclear receptor peroxisome proliferator-activated receptor alpha (ppar alpha) as the master regulator of lipid and lipoprotein homeostasis, and the rapid development of a parallel screening approach to evaluate activity towards other ppar subtypes (ppar delta, and ppar gamma) have provided an opportunity to develop novel ppar alpha-selective, ppar alpha/gamma dual, and ppar pan agonists. |
2005-02-09 |
2023-08-12 |
Not clear |
| Lucília Saraiva, Paula Fresco, Eugénia Pinto, Jorge Gonçalve. Characterization of phorbol esters activity on individual mammalian protein kinase C isoforms, using the yeast phenotypic assay. European journal of pharmacology. vol 491. issue 2-3. 2005-02-07. PMID:15140626. |
an alternative in vivo assay, based on growth inhibition of yeast expressing an individual mammalian protein kinase c (pkc) isoform (proportional to the degree of pkc activation), was used to characterize the activities of phorbol-12-myristate-13-acetate (pma) and its analogues on classical (alpha and betai), novel (delta and eta) and atypical (zeta) pkc isoforms. |
2005-02-07 |
2023-08-12 |
Not clear |
| Yijun Gu, Jianxia Guo, Ajay Pal, Su-Shu Pan, Piotr Zimniak, Shivendra V Singh, Xinhua J. Crystal structure of human glutathione S-transferase A3-3 and mechanistic implications for its high steroid isomerase activity. Biochemistry. vol 43. issue 50. 2005-02-07. PMID:15595823. |
despite considerable amino acid sequence identity with other human class alpha gsts (e.g., hgsta1-1), hgsta3-3 is unique due to its exceptionally high steroid double bond isomerase activity for the transformation of delta(5)-androstene-3,17-dione (delta(5)-ad) to delta(4)-androstene-3,17-dione. |
2005-02-07 |
2023-08-12 |
human |
| Gennaro Giordano, Ana M Sanchez-Perez, Maria Burgal, Carmina Montoliu, Lucio G Costa, Vicente Felip. Chronic exposure to ammonia induces isoform-selective alterations in the intracellular distribution and NMDA receptor-mediated translocation of protein kinase C in cerebellar neurons in culture. Journal of neurochemistry. vol 92. issue 1. 2005-02-02. PMID:15606904. |
nmda-induced translocation of pkc alpha and beta is prevented by ammonia, whereas pkc gamma, delta, epsilon, or theta; translocation is not affected. |
2005-02-02 |
2023-08-12 |
Not clear |