| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Ichimiya, H Arai, K Kosaka, R Iizuk. Morphological and biochemical changes in the cholinergic and monoaminergic systems in Alzheimer-type dementia. Acta neuropathologica. vol 70. issue 2. 1986-09-16. PMID:3739621. |
these findings suggest that various neurotransmitter systems, including cholinergic, noradrenergic and serotonergic systems, are affected in the atd brains. |
1986-09-16 |
2023-08-11 |
Not clear |
| P J Monroe, K Michaux, D J Smit. Evaluation of the direct actions of drugs with a serotonergic link in spinal analgesia on the release of [3H]serotonin from spinal cord synaptosomes. Neuropharmacology. vol 25. issue 3. 1986-06-06. PMID:3517671. |
on the other hand, a small population of serotonergic nerves critical for analgesia may be involved and are not detected using tissue from the whole spinal cord, however, it seems equally plausible that these drugs may produce their antinociceptive action through interactions with other neurotransmitter systems that in turn interface with the serotonergic nerves, perhaps through interneurons or collateral connections. |
1986-06-06 |
2023-08-11 |
rat |
| H Baran, G Sperk, H Hörtnagl, G Sapetschnig, O Hornykiewic. Alpha 2-adrenoceptors modulate kainic acid-induced limbic seizures. European journal of pharmacology. vol 113. issue 2. 1985-11-14. PMID:2995067. |
the characteristic neurochemical changes induced by s.c. kainic acid were a decrease in noradrenaline and an increase in 5-hydroxyindoleacetic acid in the acute (3 h after kainic acid injection) suggesting strongly increased neurotransmitter turnover in noradrenergic and serotonergic neurons. |
1985-11-14 |
2023-08-11 |
Not clear |
| J M Gerhart, J S Hong, H A Tilso. Studies on the mechanism of chlordecone-induced tremor in rats. Neurotoxicology. vol 6. issue 1. 1985-06-18. PMID:2581196. |
although no one neurotransmitter system appears necessary for tremor, the serotonergic, gabaergic, and cholinergic systems appear to contribute to chlordecone-induced tremor. |
1985-06-18 |
2023-08-11 |
rat |
| E B Hollingsworth, G A Patric. Involvement of the serotonergic system in the prolongation of pentobarbital sleeping time produced by prostaglandin D2. Pharmacology, biochemistry, and behavior. vol 22. issue 3. 1985-05-29. PMID:2859604. |
the role of the serotonergic neurotransmitter system in the depressant action of pgd2 was investigated with drugs which modulate this system. |
1985-05-29 |
2023-08-11 |
mouse |
| E B Hollingsworth, G A Patric. Involvement of the serotonergic system in the prolongation of pentobarbital sleeping time produced by prostaglandin D2. Pharmacology, biochemistry, and behavior. vol 22. issue 3. 1985-05-29. PMID:2859604. |
these data suggest that the depressant actions of pgd2 are linked to the serotonergic neurotransmitter system. |
1985-05-29 |
2023-08-11 |
mouse |
| T J Crow, A J Cross, S J Cooper, J F Deakin, I N Ferrier, J A Johnson, M H Joseph, F Owen, M Poulter, R Lofthous. Neurotransmitter receptors and monoamine metabolites in the brains of patients with Alzheimer-type dementia and depression, and suicides. Neuropharmacology. vol 23. issue 12B. 1985-04-17. PMID:6084823. |
noradrenergic, serotonergic, and other neurotransmitter receptors were found to be unchanged, although there was a moderate decrease in imipramine binding in a small group (n = 6) of subjects with a history of depression, who had committed suicide. |
1985-04-17 |
2023-08-12 |
human |
| C K Mitchell, D A Redbur. Analysis of pre- and postsynaptic factors of the serotonin system in rabbit retina. The Journal of cell biology. vol 100. issue 1. 1985-02-15. PMID:3965480. |
these data strongly suggest that rabbit retina contains virtually all of the molecular components required for a functional serotonergic neurotransmitter system. |
1985-02-15 |
2023-08-11 |
rabbit |
| R K Koerber, R Torkelson, G Haven, J Donaldson, S M Cohen, M Cas. Increased cerebrospinal fluid 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in Kleine-Levin syndrome. Neurology. vol 34. issue 12. 1985-01-09. PMID:6209595. |
these findings indicate that many symptoms of the kleine-levin syndrome are a result of a neurotransmitter imbalance in the serotonergic pathway of the brainstem. |
1985-01-09 |
2023-08-12 |
Not clear |
| K M Kantak, L R Hegstrand, B Eichelma. Regional changes in monoamines and metabolites following defensive aggression in the rat. Brain research bulletin. vol 12. issue 3. 1984-07-19. PMID:6202379. |
pharmacological studies have demonstrated that shock-induced defensive fighting is modulated by manipulations of the serotonergic, noradrenergic and dopaminergic neurotransmitter systems. |
1984-07-19 |
2023-08-12 |
rat |
| L J Siever, D L Murphy, S Slater, E de la Vega, S Lippe. Plasma prolactin changes following fenfluramine in depressed patients compared to controls: an evaluation of central serotonergic responsivity in depression. Life sciences. vol 34. issue 11. 1984-04-26. PMID:6700367. |
in an attempt to evaluate the responsiveness of the serotonergic neurotransmitter system in depression, fenfluramine, a serotonin releasing agent, was administered to 18 depressed patients and 10 controls, and placebo was administered to 16 of the depressed patients in a double-blind paradigm. |
1984-04-26 |
2023-08-12 |
Not clear |
| A Barbe. Properties of the serotonergic cerebral ganglion neurons of the gastropod mollusc, Philine aperta. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. vol 76. issue 1. 1984-01-27. PMID:6139241. |
because they appear to contain serotonin, and since they probably also use serotonin as a neurotransmitter, these neurons were named the serotonergic cerebral neurons (scns). |
1984-01-27 |
2023-08-12 |
Not clear |
| P Preziosi, F Cerrito, M Vacc. Effects of naloxone on the secretion of prolactin and corticosterone induced by 5-hydroxytryptophan and a serotonergic agonist, mCPP. Life sciences. vol 32. issue 21. 1983-07-08. PMID:6602260. |
the results suggest that endogenous opioids may be involved in the increase in serum level of prolactin induced by 5-hydroxytryptophan and also indicate the existence of different serotonergic neurotransmitter circuits capable of modulating the release of prolactin and corticosterone. |
1983-07-08 |
2023-08-12 |
rat |
| H Schoemaker, T P Davis, N W Pedigo, A Chen, E S Berens, P Ragan, N C Ling, H I Yamamur. Identification of beta-endorphin-6(16-17) as the principal metabolite of des-tyrosin-gamma-endorphin (DTgammaE) in vitro and assessment of its activity in neurotransmitter receptor binding assays. European journal of pharmacology. vol 81. issue 3. 1982-12-02. PMID:6126374. |
neurotransmitter receptor binding experiments showed that beta-endorphin-(6-17) was inactive at central dopaminergic, serotonergic, muscarinic, benzodiazepine and opiate receptors measured in vitro. |
1982-12-02 |
2023-08-12 |
rat |
| G R Breese, R A Mueller, R B Mailman, G D Fry. Effects of TRH on central nervous system function. Progress in clinical and biological research. vol 68. 1982-01-20. PMID:6117881. |
various studies of neurotransmitter interactions with trh have provided evidence that noradrenergic, serotonergic, gabaergic, and cholinergic systems may be influenced by trh or mediate some of its actions. |
1982-01-20 |
2023-08-12 |
Not clear |
| N S Buckholtz, J G Ond. Tetrahydro-beta-carbolines elevate plasma prolactin in male rats. Endocrine research communications. vol 7. issue 4. 1981-05-13. PMID:7472259. |
previous evidence indicated that the th beta c's interact relatively selectively with the serotonergic neurotransmitter system to increase serotonergic function. |
1981-05-13 |
2023-08-12 |
rat |
| W J Freed, D R Weinberger, L A Bing, R J Wyat. Neuropharmacological studies of phencyclidine (PCP)-induced behavioral stimulation in mice. Psychopharmacology. vol 71. issue 3. 1981-03-27. PMID:6109351. |
these findings suggest that chlorpromazine, clozapine, yohimbine, and methysergide may share a property that is unlike their primary known modes of action on dopaminergic, alpha-noradrenergic, and serotonergic neurotransmitter systems, and that this property accounts for their ability to block pcp. |
1981-03-27 |
2023-08-12 |
mouse |
| S La. Pathophysiology and pharmacotherapy of spasmodic torticollis: a review. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 6. issue 4. 1980-07-12. PMID:94551. |
because of the heterogeneity of st, investigations aimed at establishing a neurotransmitter profile for each patient by observing the acute response to a test dose of drugs affecting cholinergic, dopaminergic, serotonergic, and gamma-aminobutyric acid systems may provide a more rational basis to the selection of treatment. |
1980-07-12 |
2023-08-11 |
Not clear |
| V M Pickel, T H Joh, D J Rei. A serotonergic innervation of noradrenergic neurons in nucleus locus coeruleus: demonstration by immunocytochemical localization of the transmitter specific enzymes tyrosine and tryptophan hydroxylase. Brain research. vol 131. issue 2. 1977-10-14. PMID:19125. |
immunocytochemical localization of the neurotransmitter synthesizing enzymes, tyrosine and tryptophan hydroxylase, was used to determine whether the noradrenergic neurons in the nucleus locus coeruleus of the rat are innervated by serotonergic (5-ht) neurons. |
1977-10-14 |
2023-08-11 |
rat |
| M Brunelli, V Castellucci, E R Kande. Synaptic facilitation and behavioral sensitization in Aplysia: possible role of serotonin and cyclic AMP. Science (New York, N.Y.). vol 194. issue 4270. 1977-01-25. PMID:186870. |
the mechanism of presynaptic facilitation, therefore, may include activation of one or more serotonergic neurons, which enhance the release of a neurotransmitter by increasing the intracellular concentration of cyclic amp in the terminals of the sensory neurons. |
1977-01-25 |
2023-08-11 |
aplysia |