| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H M Pappiu. Neurochemical approaches to the amelioration of brain injury. Journal of neural transmission. Supplementum. vol 29. 1990-08-01. PMID:1694229. |
in particular, they are part of an effort to elucidate the involvement of both the serotonergic and noradrenergic neurotransmitter systems in the wide-spread decrease in cortical glucose utilization, interpreted as reflecting a functional depression, associated with a focal cortical lesion in the rat. |
1990-08-01 |
2023-08-11 |
rat |
| W Dimpfel, M Spüler, D Bonk. Influence of repeated vitamin B administration on the frequency pattern analysed from rat brain electrical activity (Tele-Stereo-EEG). Klinische Wochenschrift. vol 68. issue 2. 1990-05-03. PMID:2157086. |
this higher sensitivity to a morphine challenge persisted for more than 1 week after the end of the vitamin treatment which points to a plastic change in serotonergic neurotransmitter control processes. |
1990-05-03 |
2023-08-11 |
rat |
| A Ghahary, J Vriend, K W Chen. Modification of the indolamine content in neuroblastoma x glioma hybrid NG108-15 cells upon induced differentiation. Cellular and molecular neurobiology. vol 9. issue 3. 1990-03-01. PMID:2482134. |
the clonal ng108-15 cell line is also catecholaminergic, in addition to cholinergic and serotonergic; and a shift of neurotransmitter pattern from serotonin to dopamine production occurs during morphological differentiation. |
1990-03-01 |
2023-08-11 |
Not clear |
| M G van Luijtelaar, H W Steinbusch, J A Tonnae. Similarities between aberrant serotonergic fibers in the aged and 5,7-DHT denervated young adult rat brain. Experimental brain research. vol 78. issue 1. 1990-01-22. PMID:2591520. |
recent morphological observations have suggested neurotransmitter specific degeneration of amongst others, the serotonergic system in the aged rat brain. |
1990-01-22 |
2023-08-11 |
rat |
| H J Altman, S O Ogren, R F Berman, H J Normil. The effects of p-chloroamphetamine, a depletor of brain serotonin, on the performance of rats in two types of positively reinforced complex spatial discrimination tasks. Behavioral and neural biology. vol 52. issue 2. 1989-11-01. PMID:2478115. |
while it is clear from these and other studies that the serotonergic nervous system plays an important role in the processes underlying learning and memory, these results further underscore the selective role of this neurotransmitter system in the way information is processed by the brain. |
1989-11-01 |
2023-08-11 |
rat |
| G L Wen. Amnesia and Alzheimer's disease: which neurotransmitter system is responsible? Neurobiology of aging. vol 9. issue 5-6. 1989-02-16. PMID:2905431. |
the cholinergic, noradrenergic, and serotonergic neurotransmitter systems show a consistent pattern of degeneration associated with alzheimer's disease (ad) and, to a lesser extent, normal aging. |
1989-02-16 |
2023-08-11 |
Not clear |
| D Quartermain, M E Judge, P Le. Attenuation of forgetting by pharmacological stimulation of aminergic neurotransmitter systems. Pharmacology, biochemistry, and behavior. vol 30. issue 1. 1988-10-31. PMID:2902645. |
thirty min prior to testing animals were injected with either saline or different doses of drugs which activate the noradrenergic (phenylephrine, salbutamol, clonidine) dopaminergic (l-dopa(sinemet) transdihydrolisuride, apomorphine) and serotonergic (fluoxetine, 5-methoxy dmt) neurotransmitter systems. |
1988-10-31 |
2023-08-11 |
mouse |
| A E Calogero, W T Gallucci, G P Chrousos, P W Gol. Catecholamine effects upon rat hypothalamic corticotropin-releasing hormone secretion in vitro. The Journal of clinical investigation. vol 82. issue 3. 1988-10-26. PMID:2901433. |
the effect of ne upon ir-rcrh secretion is not apparently mediated by serotonergic or cholinergic interneurons, but is modulated by the inhibitory neurotransmitter, gaba. |
1988-10-26 |
2023-08-11 |
rat |
| A N Nicholson, P A Pasco. Studies on the modulation of the sleep-wakefulness continuum in man by fluoxetine, a 5-HT uptake inhibitor. Neuropharmacology. vol 27. issue 6. 1988-10-17. PMID:3262203. |
it is suggested that the serotonergic system has a pervasive influence throughout the sleep-wakefulness continuum, in contrast with some other neurotransmitter systems, which may be more concerned with the subtle manifestations of vigilance. |
1988-10-17 |
2023-08-11 |
human |
| G D Burrows, I M McIntyre, F K Judd, T R Norma. Clinical effects of serotonin reuptake inhibitors in the treatment of depressive illness. The Journal of clinical psychiatry. vol 49 Suppl. 1988-10-13. PMID:3045107. |
the serotonergic hypothesis of depression has stimulated the development of a range of chemically diverse compounds that have an exclusive effect on this neurotransmitter for potential use as antidepressant drugs. |
1988-10-13 |
2023-08-11 |
Not clear |
| A Cudennec, D Duverger, T Nishikawa, A McRae-Degueurce, E T MacKenzie, B Scatto. Influence of ascending serotonergic pathways on glucose use in the conscious rat brain. I. Effects of electrolytic or neurotoxic lesions of the dorsal and/or median raphé nucleus. Brain research. vol 444. issue 2. 1988-06-02. PMID:3359293. |
two hypotheses are advanced for this lack of change: firstly, the chronic reduction of 5-hydroxytryptamine levels is accompanied by compensatory changes in this or other neurotransmitter systems; secondly, serotonergic neurones may exert a phasic--rather than tonic--influence on glucose use in the mammalian brain. |
1988-06-02 |
2023-08-11 |
rat |
| B Eichelma. Toward a rational pharmacotherapy for aggressive and violent behavior. Hospital & community psychiatry. vol 39. issue 1. 1988-03-10. PMID:2828219. |
a substantial body of research with both animals and humans demonstrates that pharmacologic modulation of three neurotransmitter systems (the gabaergic, the noradrenergic, and the serotonergic) and electrical stimulation of regions of the brain produce marked alterations in aggressive and violent behavior. |
1988-03-10 |
2023-08-11 |
Not clear |
| S K Bhattacharya, N Das, M K Sarka. Inhibition of carrageenin-induced pedal oedema in rats by immobilisation stress. Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie. vol 187. issue 4. 1987-09-29. PMID:3114846. |
earlier studies from this laboratory have shown that the central noradrenergic, histaminergic, serotonergic and gaba-ergic neurotransmitter systems have a modulatory anti-inflammatory effect on carrageenin-induced pedal oedema. |
1987-09-29 |
2023-08-11 |
rat |
| G T Bolger, A S Basile, A J Janowsky, S M Paul, P Skolnic. Regulation of dihydropyridine calcium antagonist binding sites in the rat hippocampus following neurochemical lesions. Journal of neuroscience research. vol 17. issue 3. 1987-08-11. PMID:3037095. |
the effects of catecholaminergic, cholinergic, serotonergic, and glutaminergic terminal destruction and neurotransmitter depletion on [3h]nitrendipine binding to rat brain membranes were determined using the neurotoxins 6-hydroxydopamine, 5,7-dihydroxytryptamine, and kainic acid and the neurotransmitter-depleting agent reserpine. |
1987-08-11 |
2023-08-11 |
human |
| L J Whalley, J M Eagles, G M Bowler, J G Bennie, H R Dick, R J McGuire, G Fin. Selective effects of ECT on hypothalamic-pituitary activity. Psychological medicine. vol 17. issue 2. 1987-08-10. PMID:3037582. |
analysis of these hormonal responses in terms of the knowledge available on the neurotransmitter control of pituitary hormone release suggests that some of these hormonal responses to ect may be mediated by the activation of serotonergic neurones, while others are probably due to direct stimulation of the neuroendocrine neurones themselves. |
1987-08-10 |
2023-08-11 |
Not clear |
| C J Pirola, A Scheucher, M S Balda, S M Dabsys, S Finkielman, V E Nahmo. Serotonin mediates cardiovascular responses to acetylcholine, bradykinin, angiotensin II and norepinephrine in the lateral septal area of the rat brain. Neuropharmacology. vol 26. issue 6. 1987-07-29. PMID:2885773. |
these results suggest that the effects of acetylcholine, bradykinin and partially of angiotensin ii, depend on the release of norepinephrine and the actions of this neurotransmitter in turn depend on the integrity of the serotonergic system in the lateral septal area. |
1987-07-29 |
2023-08-11 |
rat |
| H W Steinbusch, A Beek, A L Frankhuyzen, J A Tonnaer, F H Gage, A Björklun. Functional activity of raphe neurons transplanted to the hippocampus and caudate-putamen. An immunohistochemical and neurochemical analysis in adult and aged rats. Annals of the New York Academy of Sciences. vol 495. 1987-07-29. PMID:3474940. |
the rr cell suspension, however, also showed outgrowth of other transmitter-specific neuronal systems, specifically noradrenaline and substance p. to evaluate the functional activity of the serotonergic reinnervation, we have combined immunohistochemistry and neurotransmitter release studies on adjacent hippocampus slices of adult rats. |
1987-07-29 |
2023-08-11 |
rat |
| K L Brugge, J N Hingtgen, M H Apriso. Potentiated 5-hydroxytryptophan induced response suppression in rats following chronic reserpine. Pharmacology, biochemistry, and behavior. vol 26. issue 2. 1987-06-02. PMID:3495008. |
model of depression involving the serotonergic system, we predicted the development of receptor supersensitivity of postsynaptic serotonin (5-ht) receptors due to the decreased release of this neurotransmitter as a consequence of chronic reserpine treatment. |
1987-06-02 |
2023-08-11 |
human |
| D L Murphy, C S Aulakh, N A Garric. How antidepressants work: cautionary conclusions based on clinical and laboratory studies of the longer-term consequences of antidepressant drug treatment. Ciba Foundation symposium. vol 123. 1987-04-08. PMID:3028721. |
time-dependent alterations in the functional activity of adrenergic and serotonergic neurotransmitter systems and, in particular, a frequently observed down-regulation of brain beta-adrenoceptors have been implicated in antidepressant drug effects. |
1987-04-08 |
2023-08-11 |
Not clear |
| S L Meyer, R L Goodma. Separate neural systems mediate the steroid-dependent and steroid-independent suppression of tonic luteinizing hormone secretion in the anestrous ewe. Biology of reproduction. vol 35. issue 3. 1987-02-05. PMID:2878692. |
when antagonists for 6 other neurotransmitter receptors (muscarinic and nicotinic cholinergic, gabanergic, serotonergic, opioid, and beta-adrenergic) were tested in anestrus, only cyproheptadine, the serotonergic antagonist, increased pulse frequency in ovariectomized ewes. |
1987-02-05 |
2023-08-11 |
Not clear |