| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rhyomi C Sellnow, Jordan H Newman, Nicole Chambers, Anthony R West, Kathy Steece-Collier, Ivette M Sandoval, Matthew J Benskey, Christopher Bishop, Fredric P Manfredsso. Regulation of dopamine neurotransmission from serotonergic neurons by ectopic expression of the dopamine D2 autoreceptor blocks levodopa-induced dyskinesia. Acta neuropathologica communications. vol 7. issue 1. 2020-04-02. PMID:30646956. |
it has long been hypothesized that serotonergic neurons of the dorsal raphe nucleus (drn) are capable of l-dopa uptake and dysregulated release of dopamine (da), and that this "false neurotransmission" phenomenon is a main contributor to lid development. |
2020-04-02 |
2023-08-13 |
Not clear |
| Alberto Montalbano, Boris Mlinar, Francesco Bonfiglio, Lorenzo Polenzani, Maurizio Magnani, Renato Corradett. Dual inhibitory action of trazodone on dorsal raphe serotonergic neurons through 5-HT1A receptor partial agonism and α1-adrenoceptor antagonism. PloS one. vol 14. issue 9. 2020-04-02. PMID:31557210. |
dual inhibitory action of trazodone on dorsal raphe serotonergic neurons through 5-ht1a receptor partial agonism and α1-adrenoceptor antagonism. |
2020-04-02 |
2023-08-13 |
mouse |
| Alberto Montalbano, Boris Mlinar, Francesco Bonfiglio, Lorenzo Polenzani, Maurizio Magnani, Renato Corradett. Dual inhibitory action of trazodone on dorsal raphe serotonergic neurons through 5-HT1A receptor partial agonism and α1-adrenoceptor antagonism. PloS one. vol 14. issue 9. 2020-04-02. PMID:31557210. |
in this study, we used cell-attached or whole-cell patch-clamp recordings to characterize the effects of trazodone at somatodendritic 5-ht1a receptors (5-ht1aars) and α1-adrenoceptors of serotonergic neurons in rodent dorsal raphe slices. |
2020-04-02 |
2023-08-13 |
mouse |
| Daniel Pereira Cavalcante, Larissa Córdova Turones, Gabriel Camargo-Silva, Joice Simões Santana, Diego Basile Colugnati, Aline Priscila Pansani, Carlos Henrique Xavier, Roger Luís Henschel Pobb. Role of dorsal raphe nucleus GHS-R1a receptors in the regulation of inhibitory avoidance and escape behaviors in rats. Behavioural brain research. vol 365. 2020-03-09. PMID:30857770. |
in this context, evidence shows the presence of ghs-r receptors in the dorsal raphe nucleus (drn), the main source of serotonergic neurons that innervate encephalic structures involved in emotional control. |
2020-03-09 |
2023-08-13 |
rat |
| Jicheng Li, Shaojun Yang, Xiaofeng Liu, Yuliang Han, Yanhui Li, Jingjing Feng, Hua Zha. Hypoactivity of the lateral habenula contributes to negative symptoms and cognitive dysfunction of schizophrenia in rats. Experimental neurology. vol 318. 2020-03-02. PMID:31082390. |
dopaminergic (daergic) hypofunction in the medial prefrontal cortex (mpfc) has been implicated in the negative and cognitive symptoms of schizophrenia and is regulated by serotonergic (5-htergic) neurons in the dorsal raphe nucleus (drn). |
2020-03-02 |
2023-08-13 |
rat |
| Ya Wang, Yang Liu, Jianwei Xiong, Tingting Di, Zihao Yuan, Jie Wu, Ling Che. Reduced serotonin impairs long-term depression in basolateral amygdala complex and causes anxiety-like behaviors in a mouse model of perimenopause. Experimental neurology. vol 321. 2020-02-28. PMID:31377402. |
serotonin (5-ht) synthesis in dorsal raphe nucleus (drn) and serotonergic afferents to basolateral amygdala complex (bla) were reduced in vcd-mice, which were recovered by the supplement e2. |
2020-02-28 |
2023-08-13 |
mouse |
| Jin Zhang, Shuxuan Lv, Guoyi Tang, Guanyun Bian, Yaxin Yang, Ruotong Li, Jie Yang, Jian Li. Activation of calcium-impermeable GluR2-containing AMPA receptors in the lateral habenula produces antidepressant-like effects in a rodent model of Parkinson's disease. Experimental neurology. vol 322. 2020-02-24. PMID:31499061. |
we further found that intra-lhb injection of (s)-ampa excited dopaminergic neurons in the anterior ventral tegmental area (avta) and serotonergic neurons in the dorsal raphe nucleus (drn), which increased release of da and 5-ht in the medial prefrontal cortex (mpfc), while nbqx induced the opposite effects. |
2020-02-24 |
2023-08-13 |
rat |
| James E Hassell, Victoria E Collins, Hao Li, Joshua T Rogers, Ryan C Austin, Ciprian Visceau, Kadi T Nguyen, Miles Orchinik, Christopher A Lowry, Kenneth J Renne. Local inhibition of uptake Neuroscience letters. vol 701. 2020-02-13. PMID:30776492. |
the cea has reciprocal connections with brainstem nuclei containing monoaminergic systems, including serotonergic systems arising from the dorsal raphe nucleus, which are thought to play an important role in modulation of cea-mediated behavioral responses. |
2020-02-13 |
2023-08-13 |
rat |
| Heloisa Helena Vilela-Costa, Ailton Spiacci, Isabella Galante Bissolli, Hélio Zangross. A Shift in the Activation of Serotonergic and Non-serotonergic Neurons in the Dorsal Raphe Lateral Wings Subnucleus Underlies the Panicolytic-Like Effect of Fluoxetine in Rats. Molecular neurobiology. vol 56. issue 9. 2020-01-13. PMID:30847739. |
a shift in the activation of serotonergic and non-serotonergic neurons in the dorsal raphe lateral wings subnucleus underlies the panicolytic-like effect of fluoxetine in rats. |
2020-01-13 |
2023-08-13 |
rat |
| Ya-Ping Xu, Xiang-Yu Cui, Yu-Tong Liu, Su-Ying Cui, Yong-He Zhan. Ginsenoside Rg1 promotes sleep in rats by modulating the noradrenergic system in the locus coeruleus and serotonergic system in the dorsal raphe nucleus. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 116. 2020-01-13. PMID:31154268. |
ginsenoside rg1 promotes sleep in rats by modulating the noradrenergic system in the locus coeruleus and serotonergic system in the dorsal raphe nucleus. |
2020-01-13 |
2023-08-13 |
rat |
| Ya-Ping Xu, Xiang-Yu Cui, Yu-Tong Liu, Su-Ying Cui, Yong-He Zhan. Ginsenoside Rg1 promotes sleep in rats by modulating the noradrenergic system in the locus coeruleus and serotonergic system in the dorsal raphe nucleus. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 116. 2020-01-13. PMID:31154268. |
rg1 treatment decreased the activity of noradrenergic neurons in locus coeruleus (lc) and increased the activity of serotonergic neurons in the dorsal raphe nucleus (drn). |
2020-01-13 |
2023-08-13 |
rat |
| M R Arnold, P H Williams, J A McArthur, A R Archuleta, C E O'Neill, J E Hassell, D G Smith, R K Bachtell, C A Lowr. Effects of chronic caffeine exposure during adolescence and subsequent acute caffeine challenge during adulthood on rat brain serotonergic systems. Neuropharmacology. vol 148. 2019-12-27. PMID:30579884. |
in experiment 1, acute caffeine challenge induced a widespread activation of serotonergic neurons throughout the dorsal raphe nucleus (dr); this effect was attenuated in rats that had been exposed to chronic caffeine consumption. |
2019-12-27 |
2023-08-13 |
rat |
| Sanford Pc Hsu, Dao-Yuan Wang, Ming-Yuan Min, Yu-Show F. Long-term challenge of methylphenidate changes the neuronal population and membrane property of dopaminergic neuron in rats. Neurochemistry international. vol 122. 2019-12-26. PMID:30423424. |
the number of dopaminergic neurons in the substantia nigra (sn), the serotonergic neurons in the dorsal raphe nucleus, and the cholinergic neurons in the tegmental nucleus significantly decreased as compared with normal group, whereas the noradrenergic neurons in the locus coeruleus substantially increased. |
2019-12-26 |
2023-08-13 |
rat |
| Cen Yang, Lina Zhang, Haizhi Hao, Mingzi Ran, Jiannan Li, Hailong Don. Serotonergic neurons in the dorsal raphe nucleus mediate the arousal-promoting effect of orexin during isoflurane anesthesia in male rats. Neuropeptides. vol 75. 2019-12-16. PMID:30935682. |
serotonergic neurons in the dorsal raphe nucleus mediate the arousal-promoting effect of orexin during isoflurane anesthesia in male rats. |
2019-12-16 |
2023-08-13 |
rat |
| Naoya Nishitani, Kazuki Nagayasu, Nozomi Asaoka, Mayumi Yamashiro, Chihiro Andoh, Yuma Nagai, Haruko Kinoshita, Hiroyuki Kawai, Norihiro Shibui, Beihui Liu, James Hewinson, Hisashi Shirakawa, Takayuki Nakagawa, Hitoshi Hashimoto, Sergey Kasparov, Shuji Kanek. Manipulation of dorsal raphe serotonergic neurons modulates active coping to inescapable stress and anxiety-related behaviors in mice and rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 4. 2019-12-13. PMID:30377380. |
manipulation of dorsal raphe serotonergic neurons modulates active coping to inescapable stress and anxiety-related behaviors in mice and rats. |
2019-12-13 |
2023-08-13 |
mouse |
| Naoya Nishitani, Kazuki Nagayasu, Nozomi Asaoka, Mayumi Yamashiro, Chihiro Andoh, Yuma Nagai, Haruko Kinoshita, Hiroyuki Kawai, Norihiro Shibui, Beihui Liu, James Hewinson, Hisashi Shirakawa, Takayuki Nakagawa, Hitoshi Hashimoto, Sergey Kasparov, Shuji Kanek. Manipulation of dorsal raphe serotonergic neurons modulates active coping to inescapable stress and anxiety-related behaviors in mice and rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 4. 2019-12-13. PMID:30377380. |
using these vectors, we demonstrate that acute activation of serotonergic neurons in the dorsal raphe nucleus increases active coping with inescapable stress in rats and mice in a time-locked manner, and that acute inhibition of these neurons increases anxiety-like behaviors specifically in rats. |
2019-12-13 |
2023-08-13 |
mouse |
| Naoya Nishitani, Kazuki Nagayasu, Nozomi Asaoka, Mayumi Yamashiro, Chihiro Andoh, Yuma Nagai, Haruko Kinoshita, Hiroyuki Kawai, Norihiro Shibui, Beihui Liu, James Hewinson, Hisashi Shirakawa, Takayuki Nakagawa, Hitoshi Hashimoto, Sergey Kasparov, Shuji Kanek. Manipulation of dorsal raphe serotonergic neurons modulates active coping to inescapable stress and anxiety-related behaviors in mice and rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 4. 2019-12-13. PMID:30377380. |
these findings further our understanding of the pathophysiological role of dorsal raphe serotonergic neurons in different species and the role of these neurons as therapeutic targets in major depression and anxiety disorders. |
2019-12-13 |
2023-08-13 |
mouse |
| Li Zhou, Ming-Zhe Liu, Qing Li, Juan Deng, Di Mu, Yan-Gang Su. Organization of Functional Long-Range Circuits Controlling the Activity of Serotonergic Neurons in the Dorsal Raphe Nucleus. Cell reports. vol 20. issue 8. 2019-11-20. PMID:28834759. |
organization of functional long-range circuits controlling the activity of serotonergic neurons in the dorsal raphe nucleus. |
2019-11-20 |
2023-08-13 |
Not clear |
| Paula Sm Yamashita, Daiane S Rosa, Christopher A Lowry, Helio Zangross. Serotonin actions within the prelimbic cortex induce anxiolysis mediated by serotonin 1a receptors. Journal of psychopharmacology (Oxford, England). 2019-11-20. PMID:30565963. |
the prelimbic area of the prefrontal cortex regulates serotonergic neurons within the dorsal raphe nucleus and is involved in modulating anxiety-like behavioral responses. |
2019-11-20 |
2023-08-13 |
Not clear |
| Michael V Baratta, Nathan R Leslie, Isabella P Fallon, Samuel D Dolzani, Lauren E Chun, Andrew M Tamalunas, Linda R Watkins, Steven F Maie. Behavioural and neural sequelae of stressor exposure are not modulated by controllability in females. The European journal of neuroscience. vol 47. issue 8. 2019-10-30. PMID:29359831. |
despite successful acquisition of the controlling response, behavioural control did not mitigate dorsal raphe serotonergic activation and behavioural outcomes induced by tailshock, as it does in males. |
2019-10-30 |
2023-08-13 |
rat |