| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Erica Seigneur, Jie Wang, Jinye Dai, Jai Polepalli, Thomas C Südho. Cerebellin-2 regulates a serotonergic dorsal raphe circuit that controls compulsive behaviors. Molecular psychiatry. 2021-06-23. PMID:34158618. |
taken together, our results show that cbln2 controls compulsive behaviors by regulating serotonergic circuits in the dorsal raphe. |
2021-06-23 |
2023-08-13 |
mouse |
| Sarah E Gartside, Abdurrahman Ercan Yurttaser, Amy L Burns, Nebojša Jovanović, Katie J Smith, Nana Shika Amegashiti, Bas M J Oltho. A role for nitric oxide in serotonin neurons of the midbrain raphe nuclei. The European journal of neuroscience. vol 51. issue 9. 2021-06-21. PMID:32115781. |
nnos is expressed in the dorsal raphe nucleus (drn), a source of ascending serotonergic projections. |
2021-06-21 |
2023-08-13 |
rat |
| Joanna Sowa, Grzegorz Hes. Prenatal stress-related alterations in synaptic transmission and 5-HT The European journal of neuroscience. vol 52. issue 5. 2021-06-21. PMID:32402149. |
several lines of evidence implicated an involvement of prenatal stress in alterations of the brain serotonergic system functions, but the effects of prenatal stress on its core, the dorsal raphe nucleus (drn), still remain incompletely understood. |
2021-06-21 |
2023-08-13 |
rat |
| M B Viana, R S Martins, M S C F Silva, S Xapelli, S H Vaz, A M Sebastiã. Deep Brain Stimulation of the dorsal raphe abolishes serotonin 1A facilitation of AMPA receptor-mediated synaptic currents in the ventral hippocampus. Behavioural brain research. vol 403. 2021-06-18. PMID:33476685. |
in a previous study we showed that deep brain stimulation (dbs) of the rat dorsal subregion of the dorsal raphe (drd), which sends serotonergic projections to forebrain areas, such as the ventral hippocampus, induces anxiolytic-like effects. |
2021-06-18 |
2023-08-13 |
rat |
| Zachary A Grieb, Joseph S Lonstei. Oxytocin receptor expression in the midbrain dorsal raphe is dynamic across female reproduction in rats. Journal of neuroendocrinology. vol 33. issue 2. 2021-06-15. PMID:33427399. |
changes in central otr expression across female reproduction have often been studied, but almost all of such research has focused on the forebrain, ignoring hormone-sensitive midbrain sites such as the serotonergic dorsal raphe (dr) that are also critical for postpartum behaviours. |
2021-06-15 |
2023-08-13 |
rat |
| Fabiana C Vilela, Jádina S Vieira, Fernando Vitor-Vieira, Bruna Kalil-Cutti, Josie R T da Silva, Alexandre Giusti-Paiva, Marcelo L da Silv. Maternal separation increases pain sensitivity by reducing the activity of serotonergic neurons in the dorsal raphe nucleus and noradrenergic neurons in locus coeruleus. Neuroscience letters. vol 748. 2021-06-03. PMID:33596470. |
maternal separation increases pain sensitivity by reducing the activity of serotonergic neurons in the dorsal raphe nucleus and noradrenergic neurons in locus coeruleus. |
2021-06-03 |
2023-08-13 |
rat |
| Fabiana C Vilela, Jádina S Vieira, Fernando Vitor-Vieira, Bruna Kalil-Cutti, Josie R T da Silva, Alexandre Giusti-Paiva, Marcelo L da Silv. Maternal separation increases pain sensitivity by reducing the activity of serotonergic neurons in the dorsal raphe nucleus and noradrenergic neurons in locus coeruleus. Neuroscience letters. vol 748. 2021-06-03. PMID:33596470. |
this study consisted of two experiments: 1) to confirm whether maternal separation increased pain sensitivity (n = 8 per group) and to evaluate the activity of serotonergic neurons in the dorsal raphe nucleus and noradrenergic neurons in locus coeruleus in animals subjected to maternal separation in comparison to controls (n = 6 per group); and 2) to evaluate the effect of fluoxetine (a selective 5-ht reuptake inhibitor) and desipramine (a na reuptake inhibitor) on sensitivity to chemical stimulation using formalin in animals subjected to maternal separation (n = 8 per group). |
2021-06-03 |
2023-08-13 |
rat |
| Fabiana C Vilela, Jádina S Vieira, Fernando Vitor-Vieira, Bruna Kalil-Cutti, Josie R T da Silva, Alexandre Giusti-Paiva, Marcelo L da Silv. Maternal separation increases pain sensitivity by reducing the activity of serotonergic neurons in the dorsal raphe nucleus and noradrenergic neurons in locus coeruleus. Neuroscience letters. vol 748. 2021-06-03. PMID:33596470. |
in conclusion, maternal separation increases pain sensitivity by reducing the activity of serotonergic neurons in the dorsal raphe nucleus and noradrenergic neurons in locus coeruleus. |
2021-06-03 |
2023-08-13 |
rat |
| Andrea Forero, Hsing-Ping Ku, Ana Belén Malpartida, Sina Wäldchen, Judit Alhama-Riba, Christina Kulka, Benjamin Aboagye, William H J Norton, Andrew M J Young, Yu-Qiang Ding, Robert Blum, Markus Sauer, Olga Rivero, Klaus-Peter Lesc. Serotonin (5-HT) neuron-specific inactivation of Cadherin-13 impacts 5-HT system formation and cognitive function. Neuropharmacology. vol 168. 2021-05-27. PMID:32113967. |
our results show that exclusive inactivation of cdh13 in 5-ht neurons selectively increases 5-ht neuron density in the embryonic dorsal raphe, with persistence into adulthood, and serotonergic innervation of the developing prefrontal cortex. |
2021-05-27 |
2023-08-13 |
mouse |
| Takashi Mizuhiki, Tsuyoshi Setogawa, Munetaka Shidar. Reverse-filtering on extracellular action potential for waveform analysis. Neuroscience research. vol 160. 2021-05-14. PMID:31626824. |
even using multivariate analyses, the reconstructed eaps in dorsal raphe (dr) could not be divided into different clusters possibly related to neurochemicals, suggesting that the dr neurons in the previous studies that relied on waveform criterion might contain both serotonergic and non-serotonergic neurons. |
2021-05-14 |
2023-08-13 |
Not clear |
| Alexandra N Petrucci, Katelyn G Joyal, Jonathan W Chou, Rui Li, Kimberly M Vencer, Gordon F Buchana. Post-ictal Generalized EEG Suppression is reduced by Enhancing Dorsal Raphe Serotonergic Neurotransmission. Neuroscience. vol 453. 2021-05-14. PMID:33242541. |
post-ictal generalized eeg suppression is reduced by enhancing dorsal raphe serotonergic neurotransmission. |
2021-05-14 |
2023-08-13 |
mouse |
| Burak Yaman, Ramazan Ba. Pindolol potentiates the antidepressant effect of venlafaxine by inhibiting 5-HT1A receptor in DRN neurons of mice. The International journal of neuroscience. 2021-05-10. PMID:32677492. |
antidepressants increase the level of 5-ht in the somatodendritic region of the serotonergic dorsal raphe nucleus (drn) neurons in the first few days of their usage, which, in turn, inhibits the serotonergic neurons locally. |
2021-05-10 |
2023-08-13 |
mouse |
| M R Arnold, B N Greenwood, J A McArthur, P J Clark, M Fleshner, C A Lowr. Effects of repeated voluntary or forced exercise on brainstem serotonergic systems in rats. Behavioural brain research. vol 378. 2021-04-28. PMID:31525404. |
specifically, we analyzed c-fos and fosb/Δfosb as markers of acute and chronic cellular activation, respectively, in combination with tryptophan hydroxylase, a marker of serotonergic neurons, within subregions of the dorsal raphe nucleus using immunohistochemical staining. |
2021-04-28 |
2023-08-13 |
rat |
| M R Arnold, B N Greenwood, J A McArthur, P J Clark, M Fleshner, C A Lowr. Effects of repeated voluntary or forced exercise on brainstem serotonergic systems in rats. Behavioural brain research. vol 378. 2021-04-28. PMID:31525404. |
compared to sedentary controls, rats exposed to repeated forced exercise, but not repeated voluntary exercise, displayed decreased c-fos expression in serotonergic neurons in the rostral dorsal portion of the dorsal raphe nucleus (drd) and increased c-fos expression in serotonergic neurons in the caudal dr (drc), and interfascicular part of the dorsal raphe nucleus (dri) during the active phase of the diurnal activity rhythm. |
2021-04-28 |
2023-08-13 |
rat |
| M R Arnold, B N Greenwood, J A McArthur, P J Clark, M Fleshner, C A Lowr. Effects of repeated voluntary or forced exercise on brainstem serotonergic systems in rats. Behavioural brain research. vol 378. 2021-04-28. PMID:31525404. |
similarly, increases in c-fos expression in serotonergic neurons in the drc, dri, and ventral portion of the dorsal raphe nucleus (drv) were observed in rats exposed to repeated forced exercise, compared to rats exposed to repeated voluntary exercise. |
2021-04-28 |
2023-08-13 |
rat |
| Yu Ohmura, Iku Tsutsui-Kimura, Hitomi Sasamori, Mao Nebuka, Naoya Nishitani, Kenji F Tanaka, Akihiro Yamanaka, Mitsuhiro Yoshiok. Different roles of distinct serotonergic pathways in anxiety-like behavior, antidepressant-like, and anti-impulsive effects. Neuropharmacology. vol 167. 2021-04-23. PMID:31299228. |
we demonstrated that the serotonergic activation in the median raphe nucleus enhanced anxiety-like behavior, the serotonergic activation in the dorsal raphe nucleus exerted antidepressant-like effects, and the serotonergic activation in the median or dorsal raphe nucleus suppressed impulsive action. |
2021-04-23 |
2023-08-13 |
mouse |
| Su-Ying Cui, Yuan-Li Huang, Xiang-Yu Cui, Hui-Ling Zhao, Xiao Hu, Yu-Tong Liu, Yong-He Zhan. Serotonergic system may be involved in alterations of sleep homeostasis in spontaneously hypertensive rats. Journal of sleep research. vol 29. issue 6. 2021-03-30. PMID:31726489. |
the density and activity of serotonergic neurons in the dorsal raphe nucleus were higher in spontaneously hypertensive rats compared with wistar-kyoto rats. |
2021-03-30 |
2023-08-13 |
rat |
| Rachel A Daut, J Russell Ravenel, Linda R Watkins, Steven F Maier, Laura K Fonke. The behavioral and neurochemical effects of an inescapable stressor are time of day dependent. Stress (Amsterdam, Netherlands). vol 23. issue 4. 2021-03-24. PMID:31868091. |
anxiety- and fear-related behavioral changes produced by is are driven by sensitization of serotonergic (5-hydroxytryptamine, 5-ht) neurons in the dorsal raphe nucleus (drn). |
2021-03-24 |
2023-08-13 |
rat |
| Christopher L Petersen, Alexander Koo, Bhumi Patel, Laura M Hurle. Serotonergic innervation of the auditory midbrain: dorsal raphe subregions differentially project to the auditory midbrain in male and female mice. Brain structure & function. vol 225. issue 6. 2021-03-24. PMID:32556584. |
serotonergic innervation of the auditory midbrain: dorsal raphe subregions differentially project to the auditory midbrain in male and female mice. |
2021-03-24 |
2023-08-13 |
mouse |
| Christopher L Petersen, Alexander Koo, Bhumi Patel, Laura M Hurle. Serotonergic innervation of the auditory midbrain: dorsal raphe subregions differentially project to the auditory midbrain in male and female mice. Brain structure & function. vol 225. issue 6. 2021-03-24. PMID:32556584. |
however, within the dorsal raphe nucleus (drn; b6 + b7), the source of serotonergic projections to the ic has not been resolved at the level of drn subregions. |
2021-03-24 |
2023-08-13 |
mouse |