| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P M Thompson, G Zebrowski, R S Neuma. Alteration of neocortical activity in response to noxious stimulation: participation of the dorsal raphe. Neuropharmacology. vol 30. issue 2. 1991-06-20. PMID:1827661. |
agents known to inhibit serotonergic unit activity including serotonin, (+/-)-8-hydroxy-dipropylaminotetralin, fluoxetine and baclofen, when pressure ejected in the vicinity of the dorsal raphe, prevented cortical desynchronization as well as the suppression of focal epileptiform activity in response to noxious stimulation. |
1991-06-20 |
2023-08-11 |
Not clear |
| P M Thompson, G Zebrowski, R S Neuma. Alteration of neocortical activity in response to noxious stimulation: participation of the dorsal raphe. Neuropharmacology. vol 30. issue 2. 1991-06-20. PMID:1827661. |
from these observations it is concluded that serotonergic neurones of the dorsal raphe can profoundly influence neocortical excitability and this action may underlie the clinical effectiveness of strong or noxious stimuli in suppressing epileptic seizures. |
1991-06-20 |
2023-08-11 |
Not clear |
| V Seutin, J Scuvée-Moreau, I Giesbers, L Massotte, A Dress. Effect of BHT 920 on monoaminergic neurons of the rat brain: an electrophysiological in vivo and in vitro study. Naunyn-Schmiedeberg's archives of pharmacology. vol 342. issue 5. 1991-06-03. PMID:1982557. |
in this study, the effect of this compound on the firing rate of noradrenergic locus coeruleus, serotonergic dorsal raphe and dopaminergic ventral tegmental area neurons was examined both in the anaesthetized rat and in rat brain slices. |
1991-06-03 |
2023-08-11 |
rat |
| J C Copray, R S Liem, G J Ter Horst, J D van Willige. Origin, distribution and morphology of serotonergic afferents to the mesencephalic trigeminal nucleus of the rat. Neuroscience letters. vol 121. issue 1-2. 1991-05-29. PMID:2020396. |
these serotonergic afferents originate predominantly from serotonergic cells in the dorsal raphe nucleus. |
1991-05-29 |
2023-08-11 |
rat |
| M J Moreno, M V Conde, M de la Luz Fraile, H Fernández-Lomana, A L López de Pablo, E J Marc. Lesion of the dorsal raphe nucleus induces supersensitivity to serotonin in isolated cat middle cerebral artery. Brain research. vol 538. issue 2. 1991-05-16. PMID:2012974. |
these results suggest the existence of a serotonergic innervation of the cat middle cerebral artery whose main origin might be the dorsal raphe nucleus. |
1991-05-16 |
2023-08-11 |
cat |
| A Lista, P Blier, C de Montign. Benzodiazepine receptors modulating serotonergic neurotransmission in rat hippocampus do not desensitize after long-term diazepam treatment. Brain research. vol 526. issue 1. 1991-04-26. PMID:1964107. |
previous studies have shown in the rat that long-term diazepam treatment induces a desensitization of gamma-aminobutyric acid (gaba) benzodiazepine receptors which modulate serotonergic (5-ht) neuron firing activity in the dorsal raphe. |
1991-04-26 |
2023-08-11 |
rat |
| P J Fletcher, M Davie. Dorsal raphe microinjection of 5-HT and indirect 5-HT agonists induces feeding in rats. European journal of pharmacology. vol 184. issue 2-3. 1991-04-26. PMID:2150377. |
the effects of 8-oh-dpat appear to be mediated in part in the dorsal raphe nucleus by serotonergic somatodendritic autoreceptors which normally regulate impulse flow in 5-ht dorsal raphe neurons. |
1991-04-26 |
2023-08-11 |
rat |
| P J Fletcher, M Davie. Dorsal raphe microinjection of 5-HT and indirect 5-HT agonists induces feeding in rats. European journal of pharmacology. vol 184. issue 2-3. 1991-04-26. PMID:2150377. |
the present experiments sought to examine whether suppression of dorsal raphe serotonergic neural activity induced by exogenously applied, or endogenously released 5-ht would increase feeding. |
1991-04-26 |
2023-08-11 |
rat |
| P J Fletcher, M Davie. Dorsal raphe microinjection of 5-HT and indirect 5-HT agonists induces feeding in rats. European journal of pharmacology. vol 184. issue 2-3. 1991-04-26. PMID:2150377. |
thus, increased serotonergic activity within the dorsal raphe increases feeding, presumably by inhibiting the activity of dorsal raphe 5-ht neurons. |
1991-04-26 |
2023-08-11 |
rat |
| P J Fletcher, M Davie. Dorsal raphe microinjection of 5-HT and indirect 5-HT agonists induces feeding in rats. European journal of pharmacology. vol 184. issue 2-3. 1991-04-26. PMID:2150377. |
the results are discussed in terms of the general role which serotonergic neurons arising from the dorsal raphe may play in behavioural inhibition. |
1991-04-26 |
2023-08-11 |
rat |
| C de Montigny, Y Chaput, P Blie. Modification of serotonergic neuron properties by long-term treatment with serotonin reuptake blockers. The Journal of clinical psychiatry. vol 51 Suppl B. 1991-01-30. PMID:2175309. |
in control animals, the acute intravenous administration of citalopram reduced the firing rate of dorsal raphe nucleus serotonergic neurons with an ed50 of 230 micrograms/kg. |
1991-01-30 |
2023-08-11 |
rat |
| C A Fornal, W J Litto, D A Morilak, B L Jacob. Single-unit responses of serotonergic neurons to vasoactive drug administration in behaving cats. The American journal of physiology. vol 259. issue 5 Pt 2. 1990-12-13. PMID:2146892. |
single-unit activity of serotonergic neurons in the dorsal raphe nucleus (drn), heart rate (hr), and arterial blood pressure were recorded in freely moving cats during spontaneous behavior and in response to systemic administration of vasoactive drugs. |
1990-12-13 |
2023-08-11 |
Not clear |
| C P VanderMaelen, J P Braselto. Effects of a potential antipsychotic, BMY 14802, on firing of central serotonergic and noradrenergic neurons in rats. European journal of pharmacology. vol 179. issue 3. 1990-08-13. PMID:1973108. |
the effects of acute systemic administration of this compound on spontaneously firing serotonergic dorsal raphe neurons and noradrenergic locus coeruleus neurons were assessed by means of extracellular single unit recordings in chloral hydrate anesthetized male sprague-dawley rats. |
1990-08-13 |
2023-08-11 |
rat |
| C P VanderMaelen, J P Braselto. Effects of a potential antipsychotic, BMY 14802, on firing of central serotonergic and noradrenergic neurons in rats. European journal of pharmacology. vol 179. issue 3. 1990-08-13. PMID:1973108. |
(+/-)-bmy 14802 produced inhibition of firing of serotonergic dorsal raphe neurons when given intravenously (ed50 = 0.19 mg/kg) and intragastrically (effective dose = 20 mg/kg). |
1990-08-13 |
2023-08-11 |
rat |
| J Mattila, R D Buña. Pressor and sympathetic responses to dorsal raphe nucleus infusions of TRH in rats. The American journal of physiology. vol 258. issue 6 Pt 2. 1990-08-02. PMID:2113776. |
these results are compatible with the interpretation that icv infused trh may produce its cardiovascular and sympathetic effects by acting, at least in part, on serotonergic mechanisms located in the dorsal raphe nucleus. |
1990-08-02 |
2023-08-11 |
rat |
| T R Stratford, D Wirtshafte. Ascending dopaminergic projections from the dorsal raphe nucleus in the rat. Brain research. vol 511. issue 1. 1990-06-04. PMID:1970510. |
these findings indicate that the projection pattern of th-immunoreactive cells within the dorsal raphe more closely resembles that of dopaminergic cells within the ventral tegmental area (vta) than that of serotonergic cells within the dr. |
1990-06-04 |
2023-08-11 |
rat |
| W G Liu, J C Zha. Relationship between acupuncture-induced immunity and the regulation of central neurotransmitters in the rabbit: VI. The influence of NDR stimulation on acupuncture regulation of immune function in rabbit. Acupuncture & electro-therapeutics research. vol 14. issue 3-4. 1990-04-02. PMID:2576338. |
t-lymphocyte transformation ability decreased and the function of the b-lymphocyte and mononuclear leucocyte/macrophage system increased when the activity of central serotonergic neurons was enhanced by the stimulation of nucleus dorsal raphe (ndr). |
1990-04-02 |
2023-08-11 |
rabbit |
| D Saphier, S Feldma. Paraventricular nucleus neuronal responses following electrical stimulation of the midbrain dorsal raphe: evidence for cotransmission. Experimental brain research. vol 78. issue 2. 1990-02-06. PMID:2557230. |
in order to determine the responses of paraventricular nucleus neurones following activation of central serotonergic pathways, single unit activity was recorded and responses following electrical stimulation of the midbrain dorsal raphe nucleus were examined. |
1990-02-06 |
2023-08-11 |
Not clear |
| C A Fornal, W J Litto, D A Morilak, B L Jacob. Single-unit responses of serotonergic neurons to glucose and insulin administration in behaving cats. The American journal of physiology. vol 257. issue 6 Pt 2. 1990-02-02. PMID:2690647. |
extracellular single-unit activity of serotonergic neurons in the dorsal raphe nucleus (drn) was recorded in response to glucose loading and insulin administration in conscious, freely moving cats. |
1990-02-02 |
2023-08-11 |
cat |
| L L Tseng, R Tan. Differential actions of the blockade of spinal opioid, adrenergic and serotonergic receptors on the tail-flick inhibition induced by morphine microinjected into dorsal raphe and central gray in rats. Neuroscience. vol 33. issue 1. 1990-01-26. PMID:2557562. |
differential actions of the blockade of spinal opioid, adrenergic and serotonergic receptors on the tail-flick inhibition induced by morphine microinjected into dorsal raphe and central gray in rats. |
1990-01-26 |
2023-08-11 |
rat |