| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Youssef Sar. Serotonin1B receptors: from protein to physiological function and behavior. Neuroscience and biobehavioral reviews. vol 28. issue 6. 2005-01-11. PMID:15527863. |
the regulation of gamma-aminobutyric acid release by 5-ht1b receptors has been found in projections: from caudate putamen to the globus pallidus or substantia nigra, from nucleus accumbens to the ventral tegmentum area, and from purkinje neurons to the deep nuclei of the cerebellum. |
2005-01-11 |
2023-08-12 |
human |
| Ian J Murray, Marlon A Medford, Hong-Ping Guan, Susan M Rueter, John Q Trojanowski, Virginia M-Y Le. Synphilin in normal human brains and in synucleinopathies: studies with new antibodies. Acta neuropathologica. vol 105. issue 2. 2003-04-23. PMID:12536229. |
in normal brain tissue, synphilin localized predominantly to large neurons, such as substantia nigra neurons, hippocampal pyramidal and cerebellar purkinje cells. |
2003-04-23 |
2023-08-12 |
human |
| Joanna T Pang, Paola Giunti, Susan Chamberlain, Shu F An, Roberta Vitaliani, Tomaso Scaravilli, Lillian Martinian, Nicholas W Wood, Francesco Scaravilli, Olaf Ansorg. Neuronal intranuclear inclusions in SCA2: a genetic, morphological and immunohistochemical study of two cases. Brain : a journal of neurology. vol 125. issue Pt 3. 2002-05-03. PMID:11872620. |
histological examination revealed extreme loss of pontine and olivary nuclei and purkinje cells, with preservation of the dentate nuclei, and of the pigmented cells in the substantia nigra. |
2002-05-03 |
2023-08-12 |
Not clear |
| G Moldrich, T Wenge. Localization of the CB1 cannabinoid receptor in the rat brain. An immunohistochemical study. Peptides. vol 21. issue 11. 2001-03-01. PMID:11090929. |
intensely stained neurons were observed in the principal neurons of the hippocampus, striatum, substantia nigra, cerebellar cortex, including the purkinje cells. |
2001-03-01 |
2023-08-12 |
rat |
| D Woodbury, D G Schaar, L Ramakrishnan, I B Blac. Novel structure of the human GDNF gene. Brain research. vol 803. issue 1-2. 1999-05-26. PMID:9729303. |
glial cell line-derived neurotrophic factor (gdnf) is the most potent known survival factor for substantia nigra neurons, which degenerate in parkinson's disease, for spinal motoneurons, which die in lou gehrig's disease (als), and for purkinje neurons, the critical outflow cells of the cerebellum. |
1999-05-26 |
2023-08-12 |
human |
| C Grüsser, U Grüsser-Cornehl. Improvement in motor performance of Weaver mutant mice following lesions of the cerebellum. Behavioural brain research. vol 97. issue 1-2. 1999-03-29. PMID:9867243. |
a partial loss of purkinje cells (pc) and a degeneration of dopaminergic cells in the substantia nigra have also been found. |
1999-03-29 |
2023-08-12 |
mouse |
| N Walker, I Lepee-Lorgeoux, J Fournier, C Betancur, W Rostene, P Ferrara, D Capu. Tissue distribution and cellular localization of the levocabastine-sensitive neurotensin receptor mRNA in adult rat brain. Brain research. Molecular brain research. vol 57. issue 2. 1998-10-20. PMID:9675417. |
nt-2r transcripts are diffusely distributed throughout the brain, with higher quantities found in the pia mater, the ventricles, the subfornical organ, the subiculum, the substantia nigra, the ventral tegmental area, the superior colliculus, the periaqueductal gray matter, the purkinje cells and certain hypothalamic and brainstem nuclei. |
1998-10-20 |
2023-08-12 |
rat |
| A Berthele, D J Laurie, S Platzer, W Zieglgänsberger, T R Tölle, B Somme. Differential expression of rat and human type I metabotropic glutamate receptor splice variant messenger RNAs. Neuroscience. vol 85. issue 3. 1998-08-21. PMID:9639268. |
the mglu1d messenger rna was expressed in all regions where mglu1a and -1b were detected; abundant in purkinje cells, mitral and tufted cells, and hippocampal principal neurons and interneurons, strong in thalamus and substantia nigra, and moderate in lateral septum, cortex, striatum and colliculi. |
1998-08-21 |
2023-08-12 |
human |
| J J Liang, M Cockett, X Z Khawaj. Immunohistochemical localization of G protein beta1, beta2, beta3, beta4, beta5, and gamma3 subunits in the adult rat brain. Journal of neurochemistry. vol 71. issue 1. 1998-07-09. PMID:9648884. |
no anti-gbeta4 immunostaining was observed in the pars compacta of the substantia nigra or in the cerebellar granule cell layer and purkinje cells. |
1998-07-09 |
2023-08-12 |
rat |
| G K Wenning, F Tison, Y Ben Shlomo, S E Daniel, N P Quin. Multiple system atrophy: a review of 203 pathologically proven cases. Movement disorders : official journal of the Movement Disorder Society. vol 12. issue 2. 1997-07-17. PMID:9087971. |
the main pathological change comprised cell loss and gliosis in the putamen, caudate nucleus, external pallidum, substantia nigra, locus ceruleus, inferior olives, pontine nuclei, cerebellar purkinje cells, and intermediolateral cell columns of the spinal cord. |
1997-07-17 |
2023-08-12 |
Not clear |
| Q Yan, M J Radeke, C R Matheson, J Talvenheimo, A A Welcher, S C Feinstei. Immunocytochemical localization of TrkB in the central nervous system of the adult rat. The Journal of comparative neurology. vol 378. issue 1. 1997-04-24. PMID:9120052. |
widespread and distinct staining was observed on the surface of neuronal cell bodies, axons, and dendrites in many structures, including the cerebral cortex, hippocampus, dentate gyrus, striatum, septal nuclei, substantia nigra, cerebellar purkinje cells, brainstem and spinal motor neurons, and brainstem sensory nuclei. |
1997-04-24 |
2023-08-12 |
rat |
| M Taiji, N Tohdoh, K Ojik. Neuronal expression of hippocampal cholinergic neurostimulating peptide (HCNP)-precursor mRNA in rat brain. Journal of neuroscience research. vol 45. issue 3. 1997-01-02. PMID:8841981. |
high levels were also found in the septal area, piriform cortex, entorhinal cortex, thalamic nuclei, subthalamic nuclei, medial habenular nuclei, substantia nigra, purkinje cells of the cerebellum, and choroid plexus. |
1997-01-02 |
2023-08-12 |
rat |
| P Roustan, M Abitbol, C Ménini, F Ribeaudeau, M Gérard, M Vekemans, J Mallet, J L Dufie. The rat phospholipase C beta 4 gene is expressed at high abundance in cerebellar Purkinje cells. Neuroreport. vol 6. issue 14. 1996-02-22. PMID:8547579. |
the plc beta 4 gene is expressed at high abundance in cerebellar purkinje cells and neurones of the substantia nigra, the median geniculate bodies and the thalamic nuclei. |
1996-02-22 |
2023-08-12 |
mouse |
| I Ferrer, M Olivé, R Rivera, A Pou, B Narberhaus, A Ugart. Hereditary spastic paraparesis with dementia, amyotrophy and peripheral neuropathy. A neuropathological study. Neuropathology and applied neurobiology. vol 21. issue 3. 1995-11-27. PMID:7477734. |
neuropathological findings correlate with neurological deficits, although neuron loss in the caudate and putamen, substantia nigra, and loss of purkinje cells were clinically silent. |
1995-11-27 |
2023-08-12 |
Not clear |
| T Sobreviela, D O Clary, L F Reichardt, M M Brandabur, J H Kordower, E J Mufso. TrkA-immunoreactive profiles in the central nervous system: colocalization with neurons containing p75 nerve growth factor receptor, choline acetyltransferase, and serotonin. The Journal of comparative neurology. vol 350. issue 4. 1995-04-20. PMID:7890832. |
sections stained with a pan-trk antibody that recognizes primarily trka, as well as trkb and trkc, labeled neurons within all of these regions as well as within the hypothalamic arcuate, supramammilary, and supraoptic nuclei, hippocampus, inferior and superior colliculus, substantia nigra, ventral tegmental area of t'sai, and cerebellular purkinje cells. |
1995-04-20 |
2023-08-12 |
monkey |
| E Jardim, O M Takayanagu. [Chronic nervous form of Chagas disease: clinical course and anatomopathology of a case followed-up for 20 years]. Arquivos de neuro-psiquiatria. vol 51. issue 4. 1994-05-05. PMID:8147759. |
histologic study of the central nervous system revealed demyelination of the spinocerebellar tracts and posterior columns, a great reduction in the purkinje cells number, extensive cell loss of the substantia nigra and locus coeruleus, lacunar state in the basal nuclei, tissue infiltration by aberrant herring bodies, porencephaly, and thickening of the meninges. |
1994-05-05 |
2023-08-12 |
Not clear |
| J Rodrigo, A M Suburo, M L Bentura, T Fernández, S Nakade, K Mikoshiba, R Martínez-Murillo, J M Pola. Distribution of the inositol 1,4,5-trisphosphate receptor, P400, in adult rat brain. The Journal of comparative neurology. vol 337. issue 3. 1994-02-17. PMID:8282854. |
immunoreactive neuronal cell bodies were detected in the cerebral cortex, the claustrum, the endopiriform nucleus, the corpus callosum, the anterior olfactory nuclei, the olfactory tubercle, the nucleus accumbens, the lateral septum, the bed nucleus of the stria terminalis, the hippocampal formation, the dentate gyrus, the caudate-putamen, the fundus striatum, the amygdaloid complex, the thalamus, the caudolateral part of the hypothalamus, the supramammillary nuclei, the substantia nigra, the pedunculopontine tegmental nucleus, the ventrotegmental area, the purkinje cells in the cerebellum, the dorsal cochlear nucleus, the subnucleus oralis and caudalis of trigeminal nerve, and the dorsal horn of the spinal cord. |
1994-02-17 |
2023-08-12 |
mouse |
| M Kambouris, L Sangameswaran, S R Dlouhy, M E Hodes, B Ghetti, L C Triarho. Cellular distribution of the RNA transcripts of a newly discovered gene in the brain of normal, weaver, Purkinje cell degeneration and reeler mutant mice as evidenced by in situ hybridization histochemistry. Brain research. Molecular brain research. vol 18. issue 4. 1993-08-12. PMID:8326827. |
in wild-type (+/+) brain, strong hybridization signal is seen in cerebellum, hippocampus, substantia nigra (sn), and cerebral cortex; in the cerebellum, hybridization signal is seen in granule cells, purkinje cells, and in cells of the deep cerebellar nuclei. |
1993-08-12 |
2023-08-12 |
mouse |
| R Shigemoto, S Nakanishi, N Mizun. Distribution of the mRNA for a metabotropic glutamate receptor (mGluR1) in the central nervous system: an in situ hybridization study in adult and developing rat. The Journal of comparative neurology. vol 322. issue 1. 1992-12-02. PMID:1430307. |
most intensely labeled neurons were purkinje cells of the cerebellum, mitral and tufted cells of the olfactory bulb, and neurons in the hippocampus, lateral septum, thalamus, globus pallidus, entopeduncular nucleus, ventral pallidum, magnocellular preoptic nucleus, substantia nigra, and dorsal cochlear nucleus. |
1992-12-02 |
2023-08-11 |
rat |
| E Kida, M Barcikowska, M Niemczewsk. Immunohistochemical study of a case with progressive supranuclear palsy without ophthalmoplegia. Acta neuropathologica. vol 83. issue 3. 1992-05-06. PMID:1557959. |
neuropathological examination, apart from typical changes, showed, lack of midbrain tegmentum demyelination, marked loss of purkinje cells and presence of hyalin-like bodies in individual neurons of the substantia nigra. |
1992-05-06 |
2023-08-11 |
Not clear |