| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Wegiel, H M Wisniewski, J Dziewiatkowski, E Badmajew, M Tarnawski, B Reisberg, B Mlodzik, M J De Leon, D C Mille. Cerebellar atrophy in Alzheimer's disease-clinicopathological correlations. Brain research. vol 818. issue 1. 1999-03-12. PMID:9914436. |
the 32% decrease in the total number of purkinje cells that was observed correlates with the atrophy of the molecular layer, whereas the 30% reduction in the total number of granule cells correlates with the atrophy of the molecular and granular layers. |
1999-03-12 |
2023-08-12 |
human |
| L A Stanley, A J Copp, J Pope, S Rolls, V Smelt, V H Perry, E Si. Immunochemical detection of arylamine N-acetyltransferase during mouse embryonic development and in adult mouse brain. Teratology. vol 58. issue 5. 1999-02-17. PMID:9839355. |
immunohistochemical staining of the adult mouse cerebellum revealed nat2 (the mouse homologue of human nat1) expression in the cell bodies and dendrites of purkinje cells and in the neuroglia of the molecular layer. |
1999-02-17 |
2023-08-12 |
mouse |
| D L Tolbert, J Heckrot. Purkinje cell transplants in Shaker mutant rats with hereditary Purkinje cell degeneration and ataxia. Experimental neurology. vol 153. issue 2. 1998-11-25. PMID:9784285. |
donor purkinje cells from extraparenchymal transplant sites migrated radially into the host molecular layer and differentiated. |
1998-11-25 |
2023-08-12 |
rat |
| T Nakagawa, M Sasahara, Y Hayase, M Haneda, H Yasuda, R Kikkawa, S Higashiyama, F Hazam. Neuronal and glial expression of heparin-binding EGF-like growth factor in central nervous system of prenatal and early-postnatal rat. Brain research. Developmental brain research. vol 108. issue 1-2. 1998-10-21. PMID:9693802. |
moreover, hb-egf expression was observed in the post-mitogenic cells, such as in the cells of the molecular layer, the white matter, the igl, or the purkinje cells of the cerebellum. |
1998-10-21 |
2023-08-12 |
rat |
| F Graus, S H Gultekin, I Ferrer, J Reiriz, J Alberch, J Dalma. Localization of the neuronal antigen recognized by anti-Tr antibodies from patients with paraneoplastic cerebellar degeneration and Hodgkin's disease in the rat nervous system. Acta neuropathologica. vol 96. issue 1. 1998-10-16. PMID:9678507. |
by laser confocal microscopy and immunoelectron microscopy, tr-ab immunoreactivity was found localized in the cytosol and outer surface of the endoplasmic reticulum of the perikarya of neurons of the molecular layer and the cell body and dendrites of purkinje cells without a particular concentration in dendritic spines. |
1998-10-16 |
2023-08-12 |
rat |
| P Breton, J C Bizot, J Buee, I De La Manch. Brain neurotoxicity of Penitrem A: electrophysiological, behavioral and histopathological study. Toxicon : official journal of the International Society on Toxinology. vol 36. issue 4. 1998-09-16. PMID:9643478. |
coronal sections of the brain at the striatal, thalamic, hippocampal and pons levels mainly revealed that pa was able to induce dose related injuries in the cerebellum with massive degeneration of purkinje cells and a significant vacuolization within the molecular layer. |
1998-09-16 |
2023-08-12 |
rat |
| S M Nair, Z Zhao, D K Chou, S A Tobet, F B Jungalwal. Expression of HNK-1 carbohydrate and its binding protein, SBP-1, in apposing cell surfaces in cerebral cortex and cerebellum. Neuroscience. vol 85. issue 3. 1998-08-21. PMID:9639270. |
sulfoglucuronyl carbohydrate was also expressed in purkinje neurons and their dendrites in the molecular layer and their axonal processes in the white matter. |
1998-08-21 |
2023-08-12 |
rat |
| Y J Bailly, S W Schoen, J Mariani, G W Kreutzberg, N Delhaye-Bouchau. Immature chemodifferentiation of Purkinje cell synapses revealed by 5'-nucleotidase ecto-enzyme activity in the cerebellum of the reeler mouse. Synapse (New York, N.Y.). vol 29. issue 3. 1998-08-20. PMID:9635899. |
ecto-enzyme cytochemistry reveals intense 5'-nucleotidase activity in 43% of synapses of the purkinje cells throughout the cortex and the core of the reeler cerebellar vermis, although the molecular layer displays large areas with less than 1% of labelled synapses. |
1998-08-20 |
2023-08-12 |
mouse |
| Y J Bailly, S W Schoen, J Mariani, G W Kreutzberg, N Delhaye-Bouchau. Immature chemodifferentiation of Purkinje cell synapses revealed by 5'-nucleotidase ecto-enzyme activity in the cerebellum of the reeler mouse. Synapse (New York, N.Y.). vol 29. issue 3. 1998-08-20. PMID:9635899. |
climbing fiber synapses of monoinnervated purkinje cells are labelled by 5'-nucleotidase activity in the molecular layer, as well as asymmetrical synapses made on the subjacent ectopic purkinje cells by the multiple climbing fibers and by the heterologous afferences. |
1998-08-20 |
2023-08-12 |
mouse |
| P J Kozel, R A Friedman, L C Erway, E N Yamoah, L H Liu, T Riddle, J J Duffy, T Doetschman, M L Miller, E L Cardell, G E Shul. Balance and hearing deficits in mice with a null mutation in the gene encoding plasma membrane Ca2+-ATPase isoform 2. The Journal of biological chemistry. vol 273. issue 30. 1998-08-20. PMID:9668038. |
histological analysis of the cerebellum and inner ear of mutant and wild-type mice revealed that null mutants had slightly increased numbers of purkinje neurons (in which pmca2 is highly expressed), a decreased thickness of the molecular layer, an absence of otoconia in the vestibular system, and a range of abnormalities of the organ of corti. |
1998-08-20 |
2023-08-12 |
mouse |
| H Isumi, S Takashima, K Ikeda, M Mizuguch. Expression of a 45K subunit of platelet-activating factor acetylhydrolase in the developing mouse cerebellum. Anatomy and embryology. vol 197. issue 5. 1998-08-07. PMID:9623676. |
immunohistochemical studies revealed developmental changes in the localization of pafah-45k-immunoreactivity, which shifted from the somata of purkinje cells to the neuropil of the molecular layer. |
1998-08-07 |
2023-08-12 |
mouse |
| J J Liang, M Cockett, X Z Khawaj. Immunohistochemical localization of G protein beta1, beta2, beta3, beta4, beta5, and gamma3 subunits in the adult rat brain. Journal of neurochemistry. vol 71. issue 1. 1998-07-09. PMID:9648884. |
immunoreactivity for gbeta1 was absent from the cerebellar molecular layer, and gbeta2 was not detected in the purkinje cells. |
1998-07-09 |
2023-08-12 |
rat |
| Y W Inage, M Itoh, K Wada, S Takashim. Expression of two glutamate transporters, GLAST and EAAT4, in the human cerebellum: their correlation in development and neonatal hypoxic-ischemic damage. Journal of neuropathology and experimental neurology. vol 57. issue 6. 1998-06-25. PMID:9630235. |
in neonatal hypoxic-ischemic encephalopathy (hie), glast immunoreactivity decreased in the molecular layer and increased in the inner granule cell layer at an early stage, and markedly increased in the purkinje and inner granule cell layers at a late stage. |
1998-06-25 |
2023-08-12 |
human |
| H Weissenböck, A Suchy, H Holzman. Tick-borne encephalitis in dogs: neuropathological findings and distribution of antigen. Acta neuropathologica. vol 95. issue 4. 1998-06-12. PMID:9560013. |
in the cerebellum, loss of purkinje cells and proliferation of microglial cells in the molecular layer were found. |
1998-06-12 |
2023-08-12 |
Not clear |
| M Hallonet, R M Alvarado-Mallar. The chick/quail chimeric system: a model for early cerebellar development. Perspectives on developmental neurobiology. vol 5. issue 1. 1998-06-04. PMID:9509515. |
finally we discuss data obtained in chimeric embryos with partial cerebellar grafts used to reexamine the origin and settling of several types of cortical cerebellar cells, in particular granule cells, molecular layer interneurons and purkinje cells. |
1998-06-04 |
2023-08-12 |
Not clear |
| J Ohyu, S Takashim. Decreased expression of microtubule-associated protein 5 (MAP5) in the molecular layer of cerebellum in preterm infants with olivocerebellar lesions. Brain & development. vol 20. issue 1. 1998-05-14. PMID:9533556. |
however, in cases of olivocerebellar degeneration (25-35 postmenstrual weeks), map5 immunoreactivity was reduced in the inner half of the molecular layer, especially in a portion where purkinje cells were absent. |
1998-05-14 |
2023-08-12 |
Not clear |
| J Ohyu, S Takashim. Decreased expression of microtubule-associated protein 5 (MAP5) in the molecular layer of cerebellum in preterm infants with olivocerebellar lesions. Brain & development. vol 20. issue 1. 1998-05-14. PMID:9533556. |
the ratio of the density in the outer half of the molecular layer to that in the inner half was also determined with an image analyzer, and increased significantly in purkinje cell-negative areas. |
1998-05-14 |
2023-08-12 |
Not clear |
| D K Chou, S A Tobet, F B Jungalwal. Restoration of synthesis of sulfoglucuronylglycolipids in cerebellar granule neurons promotes dedifferentiation and neurite outgrowth. The Journal of biological chemistry. vol 273. issue 14. 1998-05-07. PMID:9525965. |
several studies have suggested that the initial rise and decline in the levels of sggls and sgc-containing proteins correlated with the migration of granule neurons from the external granule cell layer to the internal granule cell layer and their subsequent maturation, whereas the later rise and continued expression of sggls in the adult was associated with their localization in the purkinje neurons and their dendrites in the molecular layer. |
1998-05-07 |
2023-08-12 |
Not clear |
| P Serôdio, B Rud. Differential expression of Kv4 K+ channel subunits mediating subthreshold transient K+ (A-type) currents in rat brain. Journal of neurophysiology. vol 79. issue 2. 1998-04-14. PMID:9463463. |
in the cerebellum kv4.3, but not kv4.2, is expressed in purkinje cells and molecular layer interneurons. |
1998-04-14 |
2023-08-12 |
rat |
| G Yang, R M Feddersen, F Zhang, H B Clark, A J Beitz, C Iadecol. Cerebellar vascular and synaptic responses in normal mice and in transgenics with Purkinje cell dysfunction. The American journal of physiology. vol 274. issue 2. 1998-03-17. PMID:9486314. |
the findings suggest that purkinje cells are responsible for a sizable component of the flow response whereas molecular layer interneurons mediate the remainder of the response. |
1998-03-17 |
2023-08-12 |
mouse |