| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S J Baloyannis, V Costa, G Deretzi, D Michmizo. Intraventricular administration of substance p increases the dendritic arborisation and the synaptic surfaces of Purkinje cells in rat's cerebellum. The International journal of neuroscience. vol 101. issue 1-4. 2000-07-07. PMID:10765993. |
numerous unattached spines of the secondary and tertiary dendritic branches of the purkinje cells were also seen in the molecular layer either free or surrounded by astrocytic sheath. |
2000-07-07 |
2023-08-12 |
rat |
| Y Saito, M Mizuguchi, A Oka, S Takashim. Fukutin protein is expressed in neurons of the normal developing human brain but is reduced in Fukuyama-type congenital muscular dystrophy brain. Annals of neurology. vol 47. issue 6. 2000-06-23. PMID:10852541. |
in the fetal cerebellum, fukutin immunoreactivity was localized to the external granule cell layer, molecular layer, purkinje cells, and some internal granular cells. |
2000-06-23 |
2023-08-12 |
human |
| J Carrasco, M Giralt, M Penkowa, A K Stalder, I L Campbell, J Hidalg. Metallothioneins are upregulated in symptomatic mice with astrocyte-targeted expression of tumor necrosis factor-alpha. Experimental neurology. vol 163. issue 1. 2000-06-13. PMID:10785443. |
increased mt-i rna levels occurred in the purkinje and granular neuronal layers of the cerebellum but also in the molecular layer. |
2000-06-13 |
2023-08-12 |
mouse |
| C L Thompson, D L Drewery, H D Atkins, F A Stephenson, P L Chazo. Immunohistochemical localization of N-methyl-D-aspartate receptor NR1, NR2A, NR2B and NR2C/D subunits in the adult mammalian cerebellum. Neuroscience letters. vol 283. issue 2. 2000-05-12. PMID:10739881. |
immunostaining with anti-nr1 antibodies was prominent in cell bodies and dendritic arbors of purkinje cells, was light to moderate in cerebellar granule cells, golgi interneurons and interneurons in the molecular layer. |
2000-05-12 |
2023-08-12 |
mouse |
| I Suárez, G Bodega, B Fernánde. Modulation of glutamate transporters (GLAST, GLT-1 and EAAC1) in the rat cerebellum following portocaval anastomosis. Brain research. vol 859. issue 2. 2000-05-09. PMID:10719077. |
in controls, eaac1 immunoreactivity in purkinje cells and glial glast and glt-1 immunoreactivities in the molecular layer (ml) increased from young to old rats. |
2000-05-09 |
2023-08-12 |
rat |
| S Kumada, M Hayashi, M Mizuguchi, I Nakano, Y Morimatsu, M Od. Cerebellar degeneration in hereditary dentatorubral-pallidoluysian atrophy and Machado-Joseph disease. Acta neuropathologica. vol 99. issue 1. 2000-03-08. PMID:10651027. |
in three subjects with drpla, who developed dementia and cerebellar ataxia at over 50 years of age, the number of purkinje cells was mildly reduced, tunel-positive cells were observed in the molecular layer of the cerebellar cortex, and immunoreactivities for calbindin d28k and excitatory amino acid transporter-1 (eaat1) were altered in the molecular layer. |
2000-03-08 |
2023-08-12 |
human |
| S Kumada, M Hayashi, M Mizuguchi, I Nakano, Y Morimatsu, M Od. Cerebellar degeneration in hereditary dentatorubral-pallidoluysian atrophy and Machado-Joseph disease. Acta neuropathologica. vol 99. issue 1. 2000-03-08. PMID:10651027. |
the lesion of purkinje cells and their processes in the molecular layer associated with altered glutamate transport may be important in drpla, while the significance of the abnormalities observed in some mjd cases, which might be related to apoptotic mechanism, remains unclear. |
2000-03-08 |
2023-08-12 |
human |
| N Poorkhalkali, K Juneblad, A C Jönsson, M Lindberg, O Karlsson, P Wallbrandt, J Ekstrand, A Lehman. Immunocytochemical distribution of the GABA(B) receptor splice variants GABA(B) R1a and R1b in the rat CNS and dorsal root ganglia. Anatomy and embryology. vol 201. issue 1. 2000-02-15. PMID:10603089. |
gbr1a-li was preferentially localised in the granule cell layer whilst gbr1b-li was mostly found in purkinje cells and in the molecular layer. |
2000-02-15 |
2023-08-12 |
rat |
| A Toledano, M I Alvarez, L Rivas, C Lacruz, R Martínez-Rodrígue. Amyloid precursor proteins in the cerebellar cortex of Alzheimer's disease patients devoid of cerebellar beta-amyloid deposits: immunocytochemical study of five cases. Journal of neural transmission (Vienna, Austria : 1996). vol 106. issue 11-12. 2000-02-15. PMID:10651111. |
accumulations of app in neurons (mainly purkinje cells) and glial cells in the upper part of the molecular layer were far greater than those in age-matched control brains and similar to those in ad brains with a beta deposits. |
2000-02-15 |
2023-08-12 |
human |
| A Toledano, M I Alvarez, L Rivas, C Lacruz, R Martínez-Rodrígue. Amyloid precursor proteins in the cerebellar cortex of Alzheimer's disease patients devoid of cerebellar beta-amyloid deposits: immunocytochemical study of five cases. Journal of neural transmission (Vienna, Austria : 1996). vol 106. issue 11-12. 2000-02-15. PMID:10651111. |
folia showed two different appearances, which were particularly well displayed in three cases: "strongly" immunopositive folia with high reactivity in purkinje cells and other neurons, and "weakly" immunopositive folia with low neuronal reactivity, but with a large number of positive glial cells in the molecular layer. |
2000-02-15 |
2023-08-12 |
human |
| P Rivas-Manzano, C Pa. Cerebellar morphological alterations in rats induced by prenatal ozone exposure. Neuroscience letters. vol 276. issue 1. 1999-12-23. PMID:10586969. |
ozone exposed rats showed cerebellar necrotic signs at age 0, diminished area of the molecular layer with purkinje cells with pale nucleoli and perinucleolar bodies at age 12, and purkinje cells showing nuclei with unusual clumps of chromatin in the periphery at age 60. |
1999-12-23 |
2023-08-12 |
rat |
| R Pascual, E Verdú, A Valero, X Navarr. Early social isolation decreases the expression of calbindin D-28k in rat cerebellar Purkinje cells. Neuroscience letters. vol 272. issue 3. 1999-12-02. PMID:10505608. |
the results indicate that purkinje cells of rats reared under early isolation show a marked loss of cad-28k immunoreactivity, and that this deficiency is recovered by later social interaction, although the thickness of the molecular layer remains reduced. |
1999-12-02 |
2023-08-12 |
rat |
| S Rees, S Breen, M Loeliger, G McCrabb, R Hardin. Hypoxemia near mid-gestation has long-term effects on fetal brain development. Journal of neuropathology and experimental neurology. vol 58. issue 9. 1999-10-07. PMID:10499436. |
in lobule 6 of the cerebella of hypoxemic fetuses, significant reductions were seen in (a) the volume density of purkinje cells (33%), (b) the width of the molecular layer (13%), (c) the area of the inner granule cell layer (13%), (d) the area of the white matter (18%), and (e) the total cross-sectional area (15%). |
1999-10-07 |
2023-08-12 |
Not clear |
| V E Okhotin, S G Kalinichenk. [Localization of NO-synthase in Lugaro cells and mechanisms of NO-ergic interactions between inhibitory interneurons of rabbit cerebellar cortex]. Morfologiia (Saint Petersburg, Russia). vol 115. issue 3. 1999-09-24. PMID:10451847. |
stellate and basket neurons of molecular layer, golgi complex and white matter neurons are nadph positive, while purkinje cells are negative to nadph-d. nadph-d-positive granule cells are found in paraflocculus and flocculus, in vermis and paramedian lobules. |
1999-09-24 |
2023-08-12 |
rabbit |
| Y Ando, N Ichihara, S Takeshita, M Nagata, T Kimura, H Tanase, T Kikuch. A new neurological mutant rat with symmetrical calcification of Purkinje cells in cerebellum. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 221. issue 4. 1999-09-10. PMID:10460698. |
pas-positive substances in the purkinje cells and extending diffusely over the lesioned sites in the molecular layer were also evident before calcification took place. |
1999-09-10 |
2023-08-12 |
rat |
| K G Baker, A J Harding, G M Halliday, J J Kril, C G Harpe. Neuronal loss in functional zones of the cerebellum of chronic alcoholics with and without Wernicke's encephalopathy. Neuroscience. vol 91. issue 2. 1999-08-02. PMID:10366000. |
a decrease in cell density and atrophy of the molecular layer, where the dendritic trees of the purkinje cells are found, without significant cell loss suggests loss of cellular dendritic structure and volume. |
1999-08-02 |
2023-08-12 |
human |
| L M Eisenman, R Brothers, M H Tran, R B Kean, G M Dickson, B Dietzschold, D C Hoope. Neonatal Borna disease virus infection in the rat causes a loss of Purkinje cells in the cerebellum. Journal of neurovirology. vol 5. issue 2. 1999-07-01. PMID:10321982. |
however, as visualized with immunohistochemistry for the purkinje cell-specific antigen calbindin, there were numerous gaps within the purkinje cell layer and in the molecular layer which contains the purkinje cell dendritic trees. |
1999-07-01 |
2023-08-12 |
rat |
| Z Nusser, Z Ahmad, V Tretter, K Fuchs, W Wisden, W Sieghart, P Somogy. Alterations in the expression of GABAA receptor subunits in cerebellar granule cells after the disruption of the alpha6 subunit gene. The European journal of neuroscience. vol 11. issue 5. 1999-05-26. PMID:10215922. |
furthermore, no change was apparent in the expression of the alpha1, beta2 and gamma2 subunits in purkinje cells and interneurons of the molecular layer. |
1999-05-26 |
2023-08-12 |
mouse |
| R Nakamura, K Kurita, T Kawanami, T Kat. An immunohistochemical study of Purkinje cells in a case of hereditary cerebellar cortical atrophy. Acta neuropathologica. vol 97. issue 2. 1999-05-18. PMID:9928832. |
we report an immunohistochemical study of purkinje cells located in the molecular layer (ectopic purkinje cells) and in the purkinje cell layer (orthotopic purkinje cells) of a patient who died young and had been diagnosed with hereditary cerebellar cortical atrophy from both clinical and neuropathological findings. |
1999-05-18 |
2023-08-12 |
Not clear |
| H B Sarnat, D E Bor. Synaptophysin immunocytochemistry with thermal intensification: a marker of terminal axonal maturation in the human fetal nervous system. Brain & development. vol 21. issue 1. 1999-05-05. PMID:10082252. |
in the cerebellum, the molecular layer shows a band of reactivity from 18 weeks; by term two parallel bands of synaptophysin are seen in the molecular layer and reactivity also is demonstrated in the purkinje and internal granular layers. |
1999-05-05 |
2023-08-12 |
human |