| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Jafferali, Y Dumont, F Sotty, Y Robitaille, R Quirion, S Ka. Insulin-like growth factor-I and its receptor in the frontal cortex, hippocampus, and cerebellum of normal human and alzheimer disease brains. Synapse (New York, N.Y.). vol 38. issue 4. 2000-12-14. PMID:11044892. |
as for the peptide itself, igf-i immunoreactivity, in normal control brains, was evident primarily in a subpopulation of astrocytes in the frontal cortex and hippocampus, and in certain purkinje cells of the cerebellum. |
2000-12-14 |
2023-08-12 |
human |
| A Li, S Sakaguchi, R Atarashi, B C Roy, R Nakaoke, K Arima, N Okimura, J Kopacek, K Shigemats. Identification of a novel gene encoding a PrP-like protein expressed as chimeric transcripts fused to PrP exon 1/2 in ataxic mouse line with a disrupted PrP gene. Cellular and molecular neurobiology. vol 20. issue 5. 2000-12-07. PMID:10930132. |
in contrast, in the brain of ngsk prnp0/0 mice, prp/prplp chimeric mrnas were expressed in neurons, at a particularly high level in hippocampus pyramidal cells and purkinje cells under the control of the prnp promoter. |
2000-12-07 |
2023-08-12 |
mouse |
| C Mallard, M Loeliger, D Copolov, S Ree. Reduced number of neurons in the hippocampus and the cerebellum in the postnatal guinea-pig following intrauterine growth-restriction. Neuroscience. vol 100. issue 2. 2000-11-28. PMID:11008170. |
at one week of age, the total number of ca1 pyramidal neurons in the hippocampus and the purkinje neurons in the cerebellum were determined using the combined fractionator/optical disector technique. |
2000-11-28 |
2023-08-12 |
Not clear |
| H Motomura, T Narahash. Temperature dependence of pyrethroid modification of single sodium channels in rat hippocampal neurons. The Journal of membrane biology. vol 177. issue 1. 2000-10-20. PMID:10960151. |
tetramethrin at 10 microm modified 17 and 23% of channels at 22 and 12 degrees c, respectively, indicating that the sensitivity of the sodium channel of rat hippocampal neurons to tetramethrin was almost the same as that of tetrodotoxin-sensitive sodium channels of rat dorsal root ganglion neurons and rat cerebellar purkinje neurons. |
2000-10-20 |
2023-08-12 |
rat |
| P M Finkenstadt, W S Kang, M Jeon, E Taira, W Tang, J M Baraba. Somatodendritic localization of Translin, a component of the Translin/Trax RNA binding complex. Journal of neurochemistry. vol 75. issue 4. 2000-10-05. PMID:10987859. |
in situ hybridization studies demonstrated that both translin and trax are expressed in neurons with prominent staining apparent in cerebellar purkinje cells and neuronal layers of the hippocampus. |
2000-10-05 |
2023-08-12 |
Not clear |
| M J Morán-Jiménez, C Matut. Immunohistochemical localization of the P2Y(1) purinergic receptor in neurons and glial cells of the central nervous system. Brain research. Molecular brain research. vol 78. issue 1-2. 2000-09-25. PMID:10891584. |
in addition, we found that the p2y(1) receptor is intensely expressed in purkinje cells, in deep layers of the cerebral cortex and in ischemic-sensitive areas of the hippocampus. |
2000-09-25 |
2023-08-12 |
rat |
| T Miyazaki, M Watanabe, A Yamagishi, M Takahash. B2 exon splicing of nonmuscle myosin heavy chain IIB is differently regulated in developing and adult rat brain. Neuroscience research. vol 37. issue 4. 2000-09-15. PMID:10958978. |
in adult, mhc-iib(deltab2) mrna was highly expressed in neurons of the cerebral cortex, hippocampus, and cerebellum, whereas mhc-iib(b2) mrna was mainly distributed in the brainstem and cerebellum, with the highest level in purkinje cells. |
2000-09-15 |
2023-08-12 |
rat |
| R Daniel, Z He, K P Carmichael, J Halper, A Batema. Cellular localization of gene expression for progranulin. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 48. issue 7. 2000-07-24. PMID:10858277. |
progranulin is expressed in immune cells in vivo and in specific neurons in the brain, including purkinje cells, pyramidal cells of the hippocampus, and some cerebral cortical neurons. |
2000-07-24 |
2023-08-12 |
Not clear |
| S M MacKenzie, C J Clark, R Fraser, C E Gómez-Sánchez, J M Connell, E Davie. Expression of 11beta-hydroxylase and aldosterone synthase genes in the rat brain. Journal of molecular endocrinology. vol 24. issue 3. 2000-07-12. PMID:10828825. |
in the brain, 11beta-hydroxylase and aldosterone synthase were detected in the cerebellum, especially the purkinje cells, as well as the hippocampus. |
2000-07-12 |
2023-08-12 |
mouse |
| I Siegle, T Klein, M H Zou, P Fritz, M Kömhof. Distribution and cellular localization of prostacyclin synthase in human brain. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 48. issue 5. 2000-06-09. PMID:10769047. |
the strongest expression of pgis was seen in large principal neurons, such as pyramidal cells of the cortex, pyramidal cells of the hippocampus, and purkinje cells of the cerebellum. |
2000-06-09 |
2023-08-12 |
human |
| K Tsutsui, K Ukena, M Usui, H Sakamoto, M Takas. Novel brain function: biosynthesis and actions of neurosteroids in neurons. Neuroscience research. vol 36. issue 4. 2000-06-07. PMID:10771104. |
these serve an excellent model for the study of physiological roles of neurosteroids in the brain, because both cerebellar purkinje neurons and hippocampal neurons play an important role in memory and learning. |
2000-06-07 |
2023-08-12 |
Not clear |
| J B Pellet, J A Haefliger, J K Staple, C Widmann, E Welker, H Hirling, C Bonny, P Nicod, S Catsicas, G Waeber, B M Riedere. Spatial, temporal and subcellular localization of islet-brain 1 (IB1), a homologue of JIP-1, in mouse brain. The European journal of neuroscience. vol 12. issue 2. 2000-05-25. PMID:10712642. |
ib1 was also detected in a restricted number of axons, as in the mossy fibres from dentate gyrus in the hippocampus, and was found in soma, dendrites and axons of cerebellar purkinje cells. |
2000-05-25 |
2023-08-12 |
mouse |
| R A Johanson, H M Sarau, J J Foley, J R Slemmo. Calmodulin-binding peptide PEP-19 modulates activation of calmodulin kinase II In situ. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 8. 2000-05-15. PMID:10751438. |
these include the granule cells of the hippocampus and the purkinje cells of the cerebellum. |
2000-05-15 |
2023-08-12 |
Not clear |
| M Giralt, A Molinero, J Carrasco, J Hidalg. Effect of dietary zinc deficiency on brain metallothionein-I and -III mRNA levels during stress and inflammation. Neurochemistry international. vol 36. issue 6. 2000-05-11. PMID:10762093. |
yet, significant decreasing effects of the zinc deficient diet were observed in areas such as the neocortex, ca1-ca3 neuronal layer and dentate gyrus of the hippocampus, and the purkinje neuronal layer of the cerebellum. |
2000-05-11 |
2023-08-12 |
mouse |
| C C Gandhi, R M Kelly1, R G Wiley, T J Wals. Impaired acquisition of a Morris water maze task following selective destruction of cerebellar purkinje cells with OX7-saporin. Behavioural brain research. vol 109. issue 1. 2000-05-03. PMID:10699656. |
bilateral icv injections of 2 microg ox7-saporin (4 microg total) in adult male rats produced substantial loss of purkinje cells (56%) throughout the cerebellum without affecting hippocampal morphology or biochemical indices of cholinergic, serotonergic, or catecholaminergic function in the hippocampus, frontal cortex, or striatum. |
2000-05-03 |
2023-08-12 |
mouse |
| M Moser, T Stempfl, Y Li, P Glynn, R Büttner, D Kretzschma. Cloning and expression of the murine sws/NTE gene. Mechanisms of development. vol 90. issue 2. 2000-04-27. PMID:10640712. |
in adult mice expression is most prominent in purkinje cells, granule cells and pyramidal neurons of the hippocampus and some large neurons in the medulla oblongata, nucleus dentatus and pons. |
2000-04-27 |
2023-08-12 |
mouse |
| Y Cao, K J Murphy, T M McIntyre, G A Zimmerman, S M Prescot. Expression of fatty acid-CoA ligase 4 during development and in brain. FEBS letters. vol 467. issue 2-3. 2000-03-31. PMID:10675551. |
in addition, facl4 was highly expressed in both adult and newborn mouse brain especially in the granule cells of the dentate gyrus and the pyramidal cell layer of ca1 in hippocampus, and the granular cell layer and purkinje cells of the cerebellum. |
2000-03-31 |
2023-08-12 |
mouse |
| W J Miller, J A Skinner, G S Foss, K E Davie. Localization of the fragile X mental retardation 2 (FMR2) protein in mammalian brain. The European journal of neuroscience. vol 12. issue 1. 2000-03-16. PMID:10651894. |
our results demonstrate for the first time that the fmr2 protein is localized in neurons of the neocortex, purkinje cells of the cerebellum and the granule cell layer of the hippocampus. |
2000-03-16 |
2023-08-12 |
mouse |
| C J Zhou, S Kikuyama, M Shibanuma, T Hirabayashi, S Nakajo, A Arimura, S Shiod. Cellular distribution of the splice variants of the receptor for pituitary adenylate cyclase-activating polypeptide (PAC(1)-R) in the rat brain by in situ RT-PCR. Brain research. Molecular brain research. vol 75. issue 1. 2000-03-07. PMID:10648899. |
with an innovative molecular histochemical technique, in situ rt-pcr, we determined that these two splice isoforms are both intensely expressed in the mitral cells of the olfactory bulb, the purkinje cells of the cerebellum, the pyramidal cells of the hippocampus and neocortex, and many neurons in the nuclei of hypothalamus and thalamus as well as other regions. |
2000-03-07 |
2023-08-12 |
rat |
| M Parra, P Gascard, L D Walensky, J A Gimm, S Blackshaw, N Chan, Y Takakuwa, T Berger, G Lee, J A Chasis, S H Snyder, N Mohandas, J G Conbo. Molecular and functional characterization of protein 4.1B, a novel member of the protein 4.1 family with high level, focal expression in brain. The Journal of biological chemistry. vol 275. issue 5. 2000-03-02. PMID:10652311. |
in situ hybridization revealed high level, focal expression of 4.1b mrna in select neuronal populations within the mouse brain, including purkinje cells of the cerebellum, pyramidal cells in hippocampal regions ca1-3, thalamic nuclei, and olfactory bulb. |
2000-03-02 |
2023-08-12 |
mouse |