| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Gardette, R M Alvarado-Mallart, F Crepel, C Sotel. Electrophysiological demonstration of a synaptic integration of transplanted Purkinje cells into the cerebellum of the adult Purkinje cell degeneration mutant mouse. Neuroscience. vol 24. issue 3. 1988-07-18. PMID:3380299. |
electrophysiological demonstration of a synaptic integration of transplanted purkinje cells into the cerebellum of the adult purkinje cell degeneration mutant mouse. |
1988-07-18 |
2023-08-11 |
mouse |
| R Gardette, R M Alvarado-Mallart, F Crepel, C Sotel. Electrophysiological demonstration of a synaptic integration of transplanted Purkinje cells into the cerebellum of the adult Purkinje cell degeneration mutant mouse. Neuroscience. vol 24. issue 3. 1988-07-18. PMID:3380299. |
after implantation of solid pieces of cerebellar primordia from 12-day-old c57bl embryos into the cerebellar parenchyma of 3- to 4-month-old "purkinje cell degeneration" mutant mice, purkinje cells from the donor leave the implant and differentiate while migrating into the host molecular layer. |
1988-07-18 |
2023-08-11 |
mouse |
| R Gardette, R M Alvarado-Mallart, F Crepel, C Sotel. Electrophysiological demonstration of a synaptic integration of transplanted Purkinje cells into the cerebellum of the adult Purkinje cell degeneration mutant mouse. Neuroscience. vol 24. issue 3. 1988-07-18. PMID:3380299. |
electrophysiological studies were performed using in vitro cerebellar slice preparations from "purkinje cell degeneration" mutants 1-2 months after grafting, when grafted purkinje cells have reached their final location in the host molecular layer and have completed their morphological differentiation. |
1988-07-18 |
2023-08-11 |
mouse |
| R Gardette, R M Alvarado-Mallart, F Crepel, C Sotel. Electrophysiological demonstration of a synaptic integration of transplanted Purkinje cells into the cerebellum of the adult Purkinje cell degeneration mutant mouse. Neuroscience. vol 24. issue 3. 1988-07-18. PMID:3380299. |
therefore, these experiments demonstrate that embryonic purkinje cells from the graft can complete differentiation in the adult host cerebellum, and establish specific synaptic contacts with the presynaptic elements previously impinging on the missing neurons of "purkinje cell degeneration" mutants. |
1988-07-18 |
2023-08-11 |
mouse |
| b' H Autio-Harmainen, A Oldfors, P Sourander, M Renlund, K Dammert, S Simil\\xc3\\xa. Neuropathology of Salla disease. Acta neuropathologica. vol 75. issue 5. 1988-07-14. PMID:3287834.' |
cerebellum showed moderate loss of purkinje cells. |
1988-07-14 |
2023-08-11 |
Not clear |
| J Hámori, J Takác. Morphological study of cerebellar transplant cocultivated with cerebral cortical graft in the anterior eye chamber. II. Purkinje cells and molecular layer. Anatomy and embryology. vol 177. issue 6. 1988-07-08. PMID:3377196. |
it was found, that while numerous spines on the main dendritic branches of purkinje cells in single cerebellar grafts were "vacant" and non-synaptic, dendritic spines of thick purkinje dendrites in double grafts were covered by large presynaptic bags. |
1988-07-08 |
2023-08-11 |
Not clear |
| K Hashimoto, Y Kurosaka, H Tanii, M Hayash. Immunochemical studies of acrylamide-associated neuropathology. Toxicology. vol 49. issue 1. 1988-06-30. PMID:3287693. |
in the cerebellum, nf of the purkinje cells were slightly stained with all 3 antibodies. |
1988-06-30 |
2023-08-11 |
rat |
| J M Kane, M W Dudley, S M Sorensen, F P Mille. 2,4-Dihydro-3H-1,2,4-triazole-3-thiones as potential antidepressant agents. Journal of medicinal chemistry. vol 31. issue 6. 1988-06-30. PMID:3373495. |
in an attempt to determine a mechanism of action, one member of this series, compound 22, was selected for further evaluation in an electrophysiological model where it was found to reduce norepinephrine function in the cerebellum as measured by the ne augmentation of gaba inhibition of purkinje neurons. |
1988-06-30 |
2023-08-11 |
mouse |
| I Ferrer, J Kulisevski, J Vazquez, G Gonzalez, M Pined. Purkinje cells in degenerative diseases of the cerebellum and its connections: a Golgi study. Clinical neuropathology. vol 7. issue 1. 1988-06-29. PMID:2453316. |
purkinje cells in degenerative diseases of the cerebellum and its connections: a golgi study. |
1988-06-29 |
2023-08-11 |
Not clear |
| I Ferrer, J Kulisevski, J Vazquez, G Gonzalez, M Pined. Purkinje cells in degenerative diseases of the cerebellum and its connections: a Golgi study. Clinical neuropathology. vol 7. issue 1. 1988-06-29. PMID:2453316. |
the cellular pathology of purkinje cells in several degenerative diseases of the cerebellum and its connections was studied with the rapid golgi method. |
1988-06-29 |
2023-08-11 |
Not clear |
| D Kumar, W R Timperle. The clinical, pathological and genetic aspects of sporadic late onset cerebellar ataxia: observations on a series of ten patients. Acta neurologica Scandinavica. vol 77. issue 3. 1988-06-27. PMID:3376743. |
histopathological examination in one patient, clinically diagnosed as multiple sclerosis, revealed complete loss of purkinje cells from the cerebellar folia with gliosis in the molecular layer and loss of small granular neurones. |
1988-06-27 |
2023-08-11 |
Not clear |
| A Neustadt, A Frostholm, A Rotte. On the cellular localization of cerebellar muscarinic receptors: an autoradiographic analysis of weaver, reeler, Purkinje cell degeneration and staggerer mice. Brain research bulletin. vol 20. issue 2. 1988-06-24. PMID:3370500. |
a substantial increase in labeling was observed in the cortex and deep nuclei of the staggerer cerebellum in which a large fraction of golgi ii cells, purkinje cells, granule cells and mossy fibers have degenerated. |
1988-06-24 |
2023-08-11 |
mouse |
| O J Castejó. Scanning electron microscopy of vertebrate cerebellar cortex. Scanning microscopy. vol 2. issue 1. 1988-06-20. PMID:3285466. |
the cerebellar circuits formed by mossy and climbing fibers with granule cell dendrites and purkinje cell-granule cell synapses have been traced by ethanol-cryofracturing technique, freeze-fracture method for sem and freeze-etching technique. |
1988-06-20 |
2023-08-11 |
mouse |
| J S Lou, J R Bloede. A study of cerebellar cortical involvement in motor learning using a new avoidance conditioning paradigm involving limb movement. Brain research. vol 445. issue 1. 1988-06-20. PMID:3365554. |
since the evaluated purkinje cells were examined in the cerebellar cortical region that contains neurons highly modulated by the intermittent application of the conditioning stimulus, these findings argue against an induction of a long-lasting modification in simple spike responses by the climbing fiber input as the basis for this type of motor learning. |
1988-06-20 |
2023-08-11 |
Not clear |
| J Tanaka, H Nakamura, S Miyawak. Cerebellar involvement in murine sphingomyelinosis: a new model of Niemann-Pick disease. Journal of neuropathology and experimental neurology. vol 47. issue 3. 1988-06-10. PMID:3130465. |
the striking neuropathological change was a marked atrophy of the cerebellum, where purkinje cells were predominantly involved. |
1988-06-10 |
2023-08-11 |
mouse |
| J Tanaka, H Nakamura, S Miyawak. Cerebellar involvement in murine sphingomyelinosis: a new model of Niemann-Pick disease. Journal of neuropathology and experimental neurology. vol 47. issue 3. 1988-06-10. PMID:3130465. |
loss of purkinje cells started at the age of six wk before the cerebellar signs had become evident clinically. |
1988-06-10 |
2023-08-11 |
mouse |
| A Rotter, C Gorenstein, A Frosthol. The localization of GABAA receptors in mice with mutations affecting the structure and connectivity of the cerebellum. Brain research. vol 439. issue 1-2. 1988-06-08. PMID:2833984. |
in the 27-29-old reeler cerebellum, where purkinje cells are malpositioned, no labeling was seen over the deep purkinje cell masses. |
1988-06-08 |
2023-08-11 |
mouse |
| O Ogawa, K Hashimoto, T Taniguchi, T Nakagawa, H Kusaka, R Takahashi, S Matsumoto, T Ima. [Subacute cerebellar degeneration with HCG-beta positive seminoma of the testis]. Hinyokika kiyo. Acta urologica Japonica. vol 33. issue 12. 1988-06-07. PMID:2452560. |
subacute cerebellar degeneration recognized in this category is characterized by acutely or subacutely progressive cerebellar ataxia and widespread loss of purkinje cells. |
1988-06-07 |
2023-08-11 |
human |
| b' I Lesn\\xc3\\xb. [The importance of Jan Evangelista Purkinje (1787-1869) for research in cerebellar structure and function]. Ceskoslovenska neurologie a neurochirurgie. vol 51. issue 1. 1988-06-02. PMID:3282700.' |
[the importance of jan evangelista purkinje (1787-1869) for research in cerebellar structure and function]. |
1988-06-02 |
2023-08-11 |
Not clear |
| D K Chou, F B Jungalwal. Sulfoglucuronyl neolactoglycolipids in adult cerebellum: specific absence in murine mutants with Purkinje cell abnormality. Journal of neurochemistry. vol 50. issue 5. 1988-06-02. PMID:3361316. |
these and other results strongly suggest that sggls and other glycolipids of the paragloboside family are localized specifically in purkinje cells and their arbors in the adult cerebellum. |
1988-06-02 |
2023-08-11 |
Not clear |