| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R J Smeyne, D Goldowit. Purkinje cell loss is due to a direct action of the weaver gene in Purkinje cells: evidence from chimeric mice. Brain research. Developmental brain research. vol 52. issue 1-2. 1990-06-04. PMID:2331788. |
within the cerebellum of the adult homozygous weaver mutant mouse there is an approximate 50% reduction in the number of vermal purkinje cells. |
1990-06-04 |
2023-08-11 |
mouse |
| R J Smeyne, D Goldowit. Purkinje cell loss is due to a direct action of the weaver gene in Purkinje cells: evidence from chimeric mice. Brain research. Developmental brain research. vol 52. issue 1-2. 1990-06-04. PMID:2331788. |
in concordance with previous work, the disorganization of the purkinje cells in the cerebellum, however, results from an indirect effect of the weaver gene. |
1990-06-04 |
2023-08-11 |
mouse |
| Y Ito, K Kohtani, T Sato, H Tauchi, T Inagaki, T Yamamot. [Micromeasurement of autofluorescent granules of the human hippocampus and cerebellum in relation to age and grade of dementia]. Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics. vol 26. issue 6. 1990-05-31. PMID:2634127. |
highly significant differences were found in the amount of pigment between the nerve cells of the granular and pyramidal layers of the hippocampus and between purkinje cells and dental nuclear cells of cerebellum. |
1990-05-31 |
2023-08-11 |
human |
| G Brochu, L Maler, R Hawke. Zebrin II: a polypeptide antigen expressed selectively by Purkinje cells reveals compartments in rat and fish cerebellum. The Journal of comparative neurology. vol 291. issue 4. 1990-05-30. PMID:2329190. |
zebrin ii: a polypeptide antigen expressed selectively by purkinje cells reveals compartments in rat and fish cerebellum. |
1990-05-30 |
2023-08-11 |
rat |
| G Brochu, L Maler, R Hawke. Zebrin II: a polypeptide antigen expressed selectively by Purkinje cells reveals compartments in rat and fish cerebellum. The Journal of comparative neurology. vol 291. issue 4. 1990-05-30. PMID:2329190. |
also as in the fish, staining in the adult rat cerebellum is confined to a subset of purkinje cells. |
1990-05-30 |
2023-08-11 |
rat |
| L J Larson-Prior, D R McCrimmon, N T Slate. Slow excitatory amino acid receptor-mediated synaptic transmission in turtle cerebellar Purkinje cells. Journal of neurophysiology. vol 63. issue 3. 1990-05-29. PMID:1970354. |
the excitatory synaptic responses of turtle purkinje cells to climbing and parallel fiber (cf and pf) stimulation have been studied by the use of intrasomatic and intradendritic recordings in intact cerebellum and brain stem-cerebellum preparations in vitro. |
1990-05-29 |
2023-08-11 |
Not clear |
| F Graus, T Ribalta, J Abos, J Alom, F Cruz-Sanchez, J Mallolas, J M Miro, A Cardesa, E Tolos. Subacute cerebellar syndrome as the first manifestation of AIDS dementia complex. Acta neurologica Scandinavica. vol 81. issue 2. 1990-05-24. PMID:2327231. |
necropsy demonstrated the typical features of the aids dementia complex and severe loss of purkinje cells of the cerebellum. |
1990-05-24 |
2023-08-11 |
human |
| D K Chou, S Flores, F B Jungalwal. Loss of sulfoglucuronyl and other neolactoglycolipids in Purkinje cell abnormality murine mutants. Journal of neurochemistry. vol 54. issue 5. 1990-05-18. PMID:1691279. |
levels of paragloboside and its other derivatives, similar to sggls, were also significantly reduced in the purkinje cell abnormality mutants pcd/pcd, sg/sg, lc/+, and nr/nr but were normal in other cerebellar mutants, such as quaking (qk/qk), weaver (wv/wv), and reeler (rl/rl), where purkinje cells are not involved. |
1990-05-18 |
2023-08-11 |
Not clear |
| D K Chou, S Flores, F B Jungalwal. Loss of sulfoglucuronyl and other neolactoglycolipids in Purkinje cell abnormality murine mutants. Journal of neurochemistry. vol 54. issue 5. 1990-05-18. PMID:1691279. |
thus, the entire paragloboside family of glycolipids is primarily associated with purkinje cells in the cerebellum. |
1990-05-18 |
2023-08-11 |
Not clear |
| D K Chou, S Flores, F B Jungalwal. Identification of disialosyl paragloboside and O-acetyldisialosyl paragloboside in cerebellum and embryonic cerebrum. Journal of neurochemistry. vol 54. issue 5. 1990-05-18. PMID:2109043. |
during development of the purkinje cell degeneration mutant, pcd/pcd, the levels of both of these gangliosides in the cerebellum declined with the loss of purkinje cells, a finding indicating that these gangliosides are primarily associated with purkinje cells. |
1990-05-18 |
2023-08-11 |
mouse |
| M Hagiwara, C Uchida, N Usuda, T Nagata, H Hidak. zeta-Related protein kinase C in nuclei of nerve cells. Biochemical and biophysical research communications. vol 168. issue 1. 1990-05-18. PMID:2327995. |
immunoblot analysis revealed that the kinase fraction was immunoreactive with a polyclonal antibody, pc-zeta, that had been raised against a peptide synthesized according to the deduced sequence of rat zeta protein kinase c. light-microscopy revealed strong immunoreactivity in the nuclei of purkinje cells in cerebellum and pyramidal cells in the rat cerebral cortex. |
1990-05-18 |
2023-08-11 |
rat |
| A Konnerth, I Llano, C M Armstron. Synaptic currents in cerebellar Purkinje cells. Proceedings of the National Academy of Sciences of the United States of America. vol 87. issue 7. 1990-05-04. PMID:1969639. |
cerebellar purkinje cells are known to receive strong excitatory input from two major pathways originating outside the cerebellum and inhibitory input from two types of neurons in the cerebellar cortex. |
1990-05-04 |
2023-08-11 |
rat |
| A Konnerth, I Llano, C M Armstron. Synaptic currents in cerebellar Purkinje cells. Proceedings of the National Academy of Sciences of the United States of America. vol 87. issue 7. 1990-05-04. PMID:1969639. |
we have used the patch-clamp technique applied to purkinje cells in thin slices of rat cerebellum to measure directly the postsynaptic currents arising from the two major excitatory pathways and one of the inhibitory inputs. |
1990-05-04 |
2023-08-11 |
rat |
| N Patil, E Lacy, M V Cha. Specific neuronal expression of human NGF receptors in the basal forebrain and cerebellum of transgenic mice. Neuron. vol 4. issue 3. 1990-05-02. PMID:2156542. |
using a monoclonal antibody specific for the human receptor, we have detected specific expression in cholinergic neurons in the basal forebrain and purkinje cells in the cerebellum during the postnatal period. |
1990-05-02 |
2023-08-11 |
mouse |
| M Ohmi, S Sato, T Ito, K Haneda, H Mohr. The effects of 5% carbon dioxide on the quantitative analysis of long-term pathology of the brain after surface hypothermia. Cryobiology. vol 27. issue 1. 1990-04-26. PMID:2107059. |
(iv) the number of purkinje cells in a 10-mm length of the cerebellum was markedly reduced to 89 in group 2b compared with 122, 134, and 117 in groups 1, 2a, and 3a, respectively. |
1990-04-26 |
2023-08-11 |
Not clear |
| M W MacCumber, C A Ross, S H Snyde. Endothelin in brain: receptors, mitogenesis, and biosynthesis in glial cells. Proceedings of the National Academy of Sciences of the United States of America. vol 87. issue 6. 1990-04-25. PMID:2156267. |
a glial role is favored by several observations: (i) mutant mice lacking neuronal purkinje cells display normal et receptor binding and enhanced stimulation by et of inositolphospholipid turnover; (ii) in weaver mice lacking neuronal granule cells, et stimulation of inositolphospholipid turnover is not significantly diminished; (iii) c6 glioma cells and primary cultures of cerebellar astroglia exhibit substantial et receptor binding and et-induced stimulation of inositolphospholipid turnover; (iv) et promotes mitogenesis of c6 glioma cells and primary cerebellar astroglia; and (v) primary cultures of cerebellar astroglia contain et mrna. |
1990-04-25 |
2023-08-11 |
mouse |
| A Suneson, H A Hansson, T Seema. Pressure wave injuries to the nervous system caused by high-energy missile extremity impact: Part II. Distant effects on the central nervous system--a light and electron microscopic study on pigs. The Journal of trauma. vol 30. issue 3. 1990-04-25. PMID:2313748. |
disintegration of nissl substance, i.e., chromatolysis, was noticed after 48 hr in many purkinje nerve cells in the cerebellum, concomitantly with the appearance of an increased frequency of association between lamellar bodies and mitochondria. |
1990-04-25 |
2023-08-11 |
Not clear |
| R R Sturroc. Age related changes in Purkinje cell number in the cerebellar nodulus of the mouse. Journal fur Hirnforschung. vol 30. issue 6. 1990-04-25. PMID:2628495. |
this suggests that loss of purkinje cells occurs in a similar fashion throughout the cerebellum despite differences in afferent and efferent connections in different regions. |
1990-04-25 |
2023-08-11 |
mouse |
| A M Heacock, E B Seguin, B W Agranof. Developmental and regional studies of the metabolism of inositol 1,4,5-trisphosphate in rat brain. Journal of neurochemistry. vol 54. issue 4. 1990-04-20. PMID:2313293. |
further support for this conclusion was obtained from studies of purkinje cell-deficient mutant mice, in which a marked decrement of cerebellar 5'-phosphatase was observed. |
1990-04-20 |
2023-08-11 |
mouse |
| O J Castejó. Surface and membrane morphology of Bergmann glial cells and their topographic relationships in the cerebellar molecular layer. Journal of submicroscopic cytology and pathology. vol 22. issue 1. 1990-04-19. PMID:2311096. |
the cerebellar bergmann glial cells of swiss albino mouse, teleost fish and human have been examined by means of freeze-fracture and ethanol-cryofracturing techniques for scanning electron microscopy and freeze-etching and thin sectioning techniques for transmission electron microscopy in order to study the outer surface, membrane morphology and topographic relationship with purkinje cells, parallel and climbing fibers and stellate axons. |
1990-04-19 |
2023-08-11 |
mouse |