| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Watanabe, L W Duche. Cerebral amyloid in human prion disease. Neuropathology and applied neurobiology. vol 19. issue 3. 1993-09-22. PMID:8355811. |
cerebellar amyloid and degeneration of granule and purkinje cells were particularly common findings in sporadic as well as in genetically determined cases. |
1993-09-22 |
2023-08-12 |
human |
| C O Hanemann, G Kuhn, A Lie, C Gillen, F Bosse, P Spreyer, H W Mülle. Expression of decorin mRNA in the nervous system of rat. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 41. issue 9. 1993-09-21. PMID:8354878. |
furthermore, in situ hybridization indicated decorin expression in purkinje neurons and cells of the molecular layer in cerebellum, and in neurons of the primary olfactory cortex and brainstem (pons). |
1993-09-21 |
2023-08-12 |
human |
| b' T L Marshak, V N Kleshchinov, V Ia Brodski\\xc4\\xa. [The DNA content of the neurons in the embryonic cerebellum transplanted into the cerebral cortex of adult rats]. Ontogenez. vol 24. issue 3. 1993-09-21. PMID:8355960.' |
it is shown that granule cells are diploid; about 3% purkinje cells contain hyperdiploid and tetraploid nuclei which corresponds to the content of such cells in the adult cerebellum. |
1993-09-21 |
2023-08-12 |
rat |
| N Dumesnil-Bousez, C Sotel. Partial reconstruction of the adult Lurcher cerebellar circuitry by neural grafting. Neuroscience. vol 55. issue 1. 1993-09-15. PMID:8350981. |
in the granule cell layer, the synaptic investment is similar to that of purkinje cells in agranular cerebellum, and even heterelogous synapses with mossy fibres have been observed. |
1993-09-15 |
2023-08-12 |
mouse |
| M B Abou-Donia, S M Ibrahim, J J Corcoran, L Lack, M A Friedman, D M Lapadul. Neurotoxicity of glycidamide, an acrylamide metabolite, following intraperitoneal injections in rats. Journal of toxicology and environmental health. vol 39. issue 4. 1993-09-08. PMID:8345532. |
a marked increase in the number of affected purkinje cells in the cerebellum, which exhibited changes ranging from pyknosis to cell death, were present. |
1993-09-08 |
2023-08-12 |
rat |
| D A Tomey, J A Heckrot. Transplantation of normal embryonic cerebellar cell suspensions into the cerebellum of lurcher mutant mice. Experimental neurology. vol 122. issue 1. 1993-09-02. PMID:8339786. |
injection of cell suspensions of normal embryonic cerebellar tissue into adult and juvenile lurcher mutant mice results in infiltration of the atrophic host cerebellar cortex by genetically normal purkinje cells, as has previously been observed in purkinje cell degeneration (pcd) mutant mice. |
1993-09-02 |
2023-08-12 |
mouse |
| J B Posne. Paraneoplastic cerebellar degeneration. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 20 Suppl 3. 1993-08-26. PMID:8334587. |
in some but not all patients, an autoantibody that reacts with the tumor and purkinje cells can be found in the serum and spinal fluid of patients with paraneoplastic cerebellar degeneration. |
1993-08-26 |
2023-08-12 |
Not clear |
| R F Butterwort. Pathophysiology of cerebellar dysfunction in the Wernicke-Korsakoff syndrome. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 20 Suppl 3. 1993-08-26. PMID:8334588. |
cerebellar pathology in wks includes severe loss of purkinje cells in superior cerebellar vermis as well as neuronal loss from the granular layer. |
1993-08-26 |
2023-08-12 |
rat |
| C Sotel. Cell interactions underlying Purkinje cell replacement by neural grafting in the pcd mutant cerebellum. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 20 Suppl 3. 1993-08-26. PMID:8334591. |
these results raise the possibility that embryonic purkinje cells can induce in adult neural cells a new type of plasticity, that of recreating a permissive microenvironment for the synaptic integration of the grafted neurons, leading to the anatomical restoration of the cortical circuit of the mutant cerebellum. |
1993-08-26 |
2023-08-12 |
mouse |
| J R Bloedel, V Bracha, P S Larso. Real time operations of the cerebellar cortex. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 20 Suppl 3. 1993-08-26. PMID:8334594. |
experiments are reviewed which illustrate: (1) that the climbing fiber inputs to purkinje cells can induce a short-lasting enhancement of their responses to mossy fiber-granule cell-parallel fiber inputs, (2) that the cerebellum is not essential for the acquisition and performance of the classically conditioned nictitating membrane reflex (nmr) of the rabbit, and (3) that the observations resulting from the microinjection of lidocaine and multiple single unit recordings within the brainstem support the notion that cell populations in this region may participate in establishing the modifications in neuronal interactions required for the acquisition of the conditioned nmr. |
1993-08-26 |
2023-08-12 |
human |
| V A Panchenko, O A Krishtal, F Tegtmeier, Tsyndrenko AY. R56865 as Ca(2+)-channel blocker in Purkinje neurons of rat: comparison with flunarizine and nimodipine. Neuroscience. vol 54. issue 3. 1993-08-19. PMID:8332250. |
the experiments were carried out on freshly isolated purkinje neurons of rat cerebellum using patch-clamp technique in the whole-cell configuration. |
1993-08-19 |
2023-08-12 |
rat |
| K M Hamre, J R Wes. The effects of the timing of ethanol exposure during the brain growth spurt on the number of cerebellar Purkinje and granule cell nuclear profiles. Alcoholism, clinical and experimental research. vol 17. issue 3. 1993-08-19. PMID:8333592. |
ethanol exposure during the brain growth spurt causes a differential loss of purkinje cells across the 10 lobules of the vermal cerebellum. |
1993-08-19 |
2023-08-12 |
rat |
| K M Hamre, J R Wes. The effects of the timing of ethanol exposure during the brain growth spurt on the number of cerebellar Purkinje and granule cell nuclear profiles. Alcoholism, clinical and experimental research. vol 17. issue 3. 1993-08-19. PMID:8333592. |
however, whether or not changing the timing of the ethanol exposure during the brain growth spurt alters the extent and location of the loss of purkinje cells within the cerebellar vermis has not been investigated. |
1993-08-19 |
2023-08-12 |
rat |
| N I Kiskin, I V Chizhmakov, Tsyndrenko AYa, O A Krishtal, F Tegtmeie. R56865 and flunarizine as Na(+)-channel blockers in isolated Purkinje neurons of rat cerebellum. Neuroscience. vol 54. issue 3. 1993-08-19. PMID:8392666. |
r56865 and flunarizine as na(+)-channel blockers in isolated purkinje neurons of rat cerebellum. |
1993-08-19 |
2023-08-12 |
rat |
| N I Kiskin, I V Chizhmakov, Tsyndrenko AYa, O A Krishtal, F Tegtmeie. R56865 and flunarizine as Na(+)-channel blockers in isolated Purkinje neurons of rat cerebellum. Neuroscience. vol 54. issue 3. 1993-08-19. PMID:8392666. |
dose-related blocking effects of r56865, flunarizine and nimodipine on voltage-activated na+ currents recorded in the whole-cell voltage clamp mode were studied in acutely isolated purkinje neurons of rat cerebellum. |
1993-08-19 |
2023-08-12 |
rat |
| S M Nair, N Prasadarao, S A Tobet, F B Jungalwal. Rostrocaudal expression of antibody HNK-1-reactive glycolipids in mouse cerebellum: relationship to developmental compartments and leaner mutation. The Journal of comparative neurology. vol 332. issue 3. 1993-08-13. PMID:8331216. |
biochemical analysis and immunocytochemical localization of sggls and other neolacto series glycolipids were studied in the leaner mutant mouse cerebellum, where a slow and progressive rostral to caudal degeneration occurs with a gradual loss of both granule cells and purkinje cells. |
1993-08-13 |
2023-08-12 |
mouse |
| S M Nair, N Prasadarao, S A Tobet, F B Jungalwal. Rostrocaudal expression of antibody HNK-1-reactive glycolipids in mouse cerebellum: relationship to developmental compartments and leaner mutation. The Journal of comparative neurology. vol 332. issue 3. 1993-08-13. PMID:8331216. |
there was a direct correlation between loss of purkinje cells and sggl-ir in the cerebellar molecular layer. |
1993-08-13 |
2023-08-12 |
mouse |
| M Kambouris, L Sangameswaran, S R Dlouhy, M E Hodes, B Ghetti, L C Triarho. Cellular distribution of the RNA transcripts of a newly discovered gene in the brain of normal, weaver, Purkinje cell degeneration and reeler mutant mice as evidenced by in situ hybridization histochemistry. Brain research. Molecular brain research. vol 18. issue 4. 1993-08-12. PMID:8326827. |
in wild-type (+/+) brain, strong hybridization signal is seen in cerebellum, hippocampus, substantia nigra (sn), and cerebral cortex; in the cerebellum, hybridization signal is seen in granule cells, purkinje cells, and in cells of the deep cerebellar nuclei. |
1993-08-12 |
2023-08-12 |
mouse |
| M Kambouris, L Sangameswaran, S R Dlouhy, M E Hodes, B Ghetti, L C Triarho. Cellular distribution of the RNA transcripts of a newly discovered gene in the brain of normal, weaver, Purkinje cell degeneration and reeler mutant mice as evidenced by in situ hybridization histochemistry. Brain research. Molecular brain research. vol 18. issue 4. 1993-08-12. PMID:8326827. |
in the granuloprival weaver (wv/wv) cerebellum, hybridization signal is seen mainly in purkinje cells. |
1993-08-12 |
2023-08-12 |
mouse |
| M Kambouris, L Sangameswaran, S R Dlouhy, M E Hodes, B Ghetti, L C Triarho. Cellular distribution of the RNA transcripts of a newly discovered gene in the brain of normal, weaver, Purkinje cell degeneration and reeler mutant mice as evidenced by in situ hybridization histochemistry. Brain research. Molecular brain research. vol 18. issue 4. 1993-08-12. PMID:8326827. |
in reeler (rl/rl) cerebellum, the strongest hybridization signal is found in a thin granule cell layer without the typical foliation pattern, while grain clusters representing ectopic purkinje cells are observed in the subcortical white matter and the area of the deep cerebellar nuclei. |
1993-08-12 |
2023-08-12 |
mouse |