| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J R Brorson, P A Manzolillo, S J Gibbons, R J Mille. AMPA receptor desensitization predicts the selective vulnerability of cerebellar Purkinje cells to excitotoxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 6. 1995-07-24. PMID:7540678. |
fluorimetric [ca2+]i imaging experiments similarly found greater responses to ampa relative to kainate in purkinje cells than in other cerebellar neurons. |
1995-07-24 |
2023-08-12 |
rat |
| J R Brorson, P A Manzolillo, S J Gibbons, R J Mille. AMPA receptor desensitization predicts the selective vulnerability of cerebellar Purkinje cells to excitotoxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 6. 1995-07-24. PMID:7540678. |
we conclude that the vulnerability of cerebellar neurons in culture to glutamate agonist-induced toxicity parallels the magnitude of the steady state currents produced, and that purkinje cells may be selectively vulnerable because they express ampa receptors which undergo less complete desensitization. |
1995-07-24 |
2023-08-12 |
rat |
| S Muras. Axonal elongation of grafted, embryonic inferior olivary neurons in the adult rat cerebellum and their synaptic formation on host Purkinje cells. Kaibogaku zasshi. Journal of anatomy. vol 70. issue 2. 1995-07-19. PMID:7785411. |
axonal elongation of grafted, embryonic inferior olivary neurons in the adult rat cerebellum and their synaptic formation on host purkinje cells. |
1995-07-19 |
2023-08-12 |
rat |
| J J Waite, A D Chen, M L Wardlow, R G Wiley, D A Lappi, L J Tha. 192 immunoglobulin G-saporin produces graded behavioral and biochemical changes accompanying the loss of cholinergic neurons of the basal forebrain and cerebellar Purkinje cells. Neuroscience. vol 65. issue 2. 1995-07-10. PMID:7777161. |
however, some purkinje cells in the superficial layers of the cerebellum were also destroyed at the higher doses of immunotoxin. |
1995-07-10 |
2023-08-12 |
rat |
| N V Hayes, F E Holmes, J Grantham, A J Baine. A60, an axonal membrane-skeletal spectrin-binding protein. Biochemical Society transactions. vol 23. issue 1. 1995-06-26. PMID:7758769. |
during post-natal cerebellar development (days 1-13) a60 is initially located in the perikarya of precursor purkinje cells and is then localized in the initial dendrites of these cells as well as in the white matter. |
1995-06-26 |
2023-08-12 |
rat |
| A Ajima, M It. A unique role of protein phosphatases in cerebellar long-term depression. Neuroreport. vol 6. issue 2. 1995-06-23. PMID:7756614. |
in order to investigate phosphorylation-dephosphorylation processes underlying long-term depression (ltd) in cerebellar purkinje cells, the protein phosphatase inhibitors calyculin a and microcystein-lr were applied to purkinje cells in guinea pig cerebellar slices either by bath application or by intracellular pressure injection. |
1995-06-23 |
2023-08-12 |
Not clear |
| D J Norman, L Feng, S S Cheng, J Gubbay, E Chan, N Heint. The lurcher gene induces apoptotic death in cerebellar Purkinje cells. Development (Cambridge, England). vol 121. issue 4. 1995-06-12. PMID:7743930. |
these data demonstrate that the lc mutation induces apoptosis in cerebellar purkinje cells following their maturation in postnatal cerebellum. |
1995-06-12 |
2023-08-12 |
mouse |
| J C Callaway, N Lasser-Ross, W N Ros. IPSPs strongly inhibit climbing fiber-activated [Ca2+]i increases in the dendrites of cerebellar Purkinje neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 15. issue 4. 1995-05-25. PMID:7722628. |
the interaction between the excitatory climbing fiber (cf) response and stellate cell inhibition was studied in guinea pig purkinje cells in sagittal slices from the cerebellar vermis. |
1995-05-25 |
2023-08-12 |
Not clear |
| A C Palmer, J B Cavanag. Encephalomyelopathy in young cats. The Journal of small animal practice. vol 36. issue 2. 1995-05-25. PMID:7723290. |
in seven animals there was loss of purkinje cells in the cerebellum and in eight there was neuronal loss in the spinal cord. |
1995-05-25 |
2023-08-12 |
cat |
| J A Nathanson, C Scavone, C Scanlon, M McKe. The cellular Na+ pump as a site of action for carbon monoxide and glutamate: a mechanism for long-term modulation of cellular activity. Neuron. vol 14. issue 4. 1995-05-23. PMID:7718240. |
carbon monoxide (co) induces a long-lasting alteration in cerebellar alpha 3-na,k-atpase independent of [na+] but linked to cgmp synthesis and localized to purkinje neurons. |
1995-05-23 |
2023-08-12 |
mouse |
| D Thomaidou, I Dori, E Patsavoud. Developmental expression and functional characterization of the 4C5 antigen in the postnatal cerebellar cortex. Journal of neurochemistry. vol 64. issue 5. 1995-05-23. PMID:7722481. |
in cerebellar primary cell cultures, 4c5 immunoreactivity was detected both on granule and on purkinje neurons. |
1995-05-23 |
2023-08-12 |
rat |
| D Mouginot, B H Gähwile. Characterization of synaptic connections between cortex and deep nuclei of the rat cerebellum in vitro. Neuroscience. vol 64. issue 3. 1995-05-18. PMID:7715782. |
this work was performed on organotypic cerebellar cultures where functional connections between purkinje cells and deep cerebellar neurons are formed de novo. |
1995-05-18 |
2023-08-12 |
rat |
| Y Sato, H Fushiki, T Kawasak. Alterations of visual climbing fiber response properties in cat cerebellar flocculus after cerebral cortical lesions. Journal of neurophysiology. vol 73. issue 1. 1995-05-17. PMID:7714573. |
in the anesthetized decorticate cat, we recorded complex spike (cs) activity together with concomitant simple spike (ss) activity of the cerebellar flocculus (fl) purkinje cells that responded to large-field visual pattern movement. |
1995-05-17 |
2023-08-12 |
cat |
| T Hirano, K Kasono, K Araki, K Shinozuka, M Mishin. Involvement of the glutamate receptor delta 2 subunit in the long-term depression of glutamate responsiveness in cultured rat Purkinje cells. Neuroscience letters. vol 182. issue 2. 1995-05-17. PMID:7715804. |
an antisense oligonucleotide against the glutamate receptor delta 2 subunit mrna, which is selectively expressed only in purkinje neurons, suppressed the induction of long-term depression (ltd) of glutamate responsiveness in the rat cerebellar culture. |
1995-05-17 |
2023-08-12 |
rat |
| X X Yan, L S Jen, L J Gare. Spatial periodicity of NADPH-diaphorase and synaptophysin, but not SNAP-25, reactivity in the monkey cerebellar cortex. Brain research. vol 669. issue 2. 1995-05-15. PMID:7712184. |
in addition, we have provided suggestive evidence of a co-expression of nadph-d and synaptophysin in selected igp modules in primate cerebellum, which suggests that nitric oxide may be involved in the activity of the purkinje cells by affecting the basket cell synaptic input. |
1995-05-15 |
2023-08-12 |
rat |
| K Kawano, M Shidar. Information representation by Purkinje cells in the cerebellum during ocular following responses. Neuroscience research. vol 21. issue 1. 1995-05-11. PMID:7708291. |
information representation by purkinje cells in the cerebellum during ocular following responses. |
1995-05-11 |
2023-08-12 |
monkey |
| K Kawano, M Shidar. Information representation by Purkinje cells in the cerebellum during ocular following responses. Neuroscience research. vol 21. issue 1. 1995-05-11. PMID:7708291. |
a quantitative analysis of simple spike activity of purkinje cells (p-cells) in the cerebellum of awake monkeys suggested their possible contribution in motor control. |
1995-05-11 |
2023-08-12 |
monkey |
| K Kawai, S Kuroda, S Watarai, H Takahash. Developmental profile of ganglioside GD3 in the central nervous system: an immunocytochemical study in the rat. Neuroscience research. vol 21. issue 1. 1995-05-11. PMID:7708295. |
in the cerebellum, immature purkinje cells and immature neuronal cells in the external and internal granular layers were also immunoreactive for gd3, the reaction product being located in the cytoplasm. |
1995-05-11 |
2023-08-12 |
mouse |
| B Brugg, Y L Dubreuil, G Huber, E E Wollman, N Delhaye-Bouchaud, J Marian. Inflammatory processes induce beta-amyloid precursor protein changes in mouse brain. Proceedings of the National Academy of Sciences of the United States of America. vol 92. issue 7. 1995-05-11. PMID:7708769. |
in the cerebellum of the staggerer mouse mutant, where a severe loss of purkinje and granule cells occurs, basal mrna levels of these interleukins were elevated and an increase in the kpi-app/app-695 ratio compared to wild-type mice was observed. |
1995-05-11 |
2023-08-12 |
mouse |
| A Mitani, H Yanase, S Namba, M Shudo, K Kataok. In vitro ischemia-induced intracellular Ca2+ elevation in cerebellar slices: a comparative study with the values found in hippocampal slices. Acta neuropathologica. vol 89. issue 1. 1995-05-10. PMID:7709726. |
when the cerebellar slice was perfused with a glucose-free physiological medium equilibrated with a 95% n2/5% co2 gas mixture (in vitro ischemic medium), a large [ca2+]i elevation was region-specifically induced in the molecular layer of the cerebellar cortex (a dendritic field of purkinje cells). |
1995-05-10 |
2023-08-12 |
Not clear |