| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Resibois, L Cuvelier, A M Goffine. Abnormalities in the cerebellum and brainstem in homozygous lurcher mice. Neuroscience. vol 80. issue 1. 1997-10-23. PMID:9252230. |
these results show that the mutation, which is semidominant in purkinje cells, is recessive in other cell groups of the cerebellum and brainstem. |
1997-10-23 |
2023-08-12 |
mouse |
| L Zhou, A Chomyn, G Attardi, C A Mille. Myoclonic epilepsy and ragged red fibers (MERRF) syndrome: selective vulnerability of CNS neurons does not correlate with the level of mitochondrial tRNAlys mutation in individual neuronal isolates. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 20. 1997-10-23. PMID:9315896. |
surprisingly, as compared with controls, neuronal loss ranged from 7% of the purkinje cells to 46% of the neurons of the dentate nucleus in merrf cerebellum. |
1997-10-23 |
2023-08-12 |
Not clear |
| A Storstein, C Vedeler, B Krossnes, S Mør. [Paraneoplastic cerebellar degeneration. A case report]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke. vol 117. issue 20. 1997-10-21. PMID:9340852. |
autopsy revealed a left ovarian adenocarcinoma and marked loss of purkinje cells in the cerebellum. |
1997-10-21 |
2023-08-12 |
Not clear |
| M L Vizuete, E Traiffort, M L Bouthenet, M Ruat, E Souil, J Tardivel-Lacombe, J C Schwart. Detailed mapping of the histamine H2 receptor and its gene transcripts in guinea-pig brain. Neuroscience. vol 80. issue 2. 1997-10-17. PMID:9284338. |
in hippocampus, cerebral and cerebellar cortex there was a selective localization of the h2 receptor messenger rna in the granule cells of dentate gyrus, pyramidal cells of the ammon's horn and cerebral cortex, and purkinje cells of cerebellum, whereas [(125)i]iodoaminopotentidine binding sites were located in layers where the dendritic trees of these messenger rna-expressing neurons extend. |
1997-10-17 |
2023-08-12 |
Not clear |
| X H Cai, K Tomizawa, D Tang, Y F Lu, A Moriwaki, M Tokuda, S Nagahata, O Hatase, H Matsu. Changes in the expression of novel Cdk5 activator messenger RNA (p39nck5ai mRNA) during rat brain development. Neuroscience research. vol 28. issue 4. 1997-10-15. PMID:9274831. |
in the adult, expression was decreased in most neurons except purkinje and granule cells in the cerebellum which retained high levels. |
1997-10-15 |
2023-08-12 |
rat |
| P L De Jager, J Zuo, S A Cook, N Heint. A new allele of the lurcher gene, lurcherJ. Mammalian genome : official journal of the International Mammalian Genome Society. vol 8. issue 9. 1997-10-08. PMID:9271665. |
in the heterozygote, this mutation results in an early loss of purkinje cells in the cerebellum, which is followed by the overt symptom of an ataxic gait first observed at postnatal day 13 (p13). |
1997-10-08 |
2023-08-12 |
mouse |
| S Naisbitt, E Kim, R J Weinberg, A Rao, F C Yang, A M Craig, M Shen. Characterization of guanylate kinase-associated protein, a postsynaptic density protein at excitatory synapses that interacts directly with postsynaptic density-95/synapse-associated protein 90. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 15. 1997-10-03. PMID:9221768. |
by in situ hybridization, gkap is expressed widely in neurons of cortex and hippocampus and in the purkinje and granule cells of the cerebellum. |
1997-10-03 |
2023-08-12 |
rat |
| X Li, A Cvekl, S Bassnett, J Piatigorsk. Lens-preferred activity of chicken delta 1- and delta 2-crystallin enhancers in transgenic mice and evidence for retinoic acid-responsive regulation of the delta 1-crystallin gene. Developmental genetics. vol 20. issue 3. 1997-09-19. PMID:9216065. |
in one case, a truncated delta 2-crystallin promoter (-308/+24) in combination with the enhancer was also active in the purkinje cells of the cerebellum of the transgenic mice, which could prove useful in future experiments. |
1997-09-19 |
2023-08-12 |
mouse |
| J Rowiński, H Kozłowska, D C Górecki, E A Barnar. Histochemical detection of dystrophin in Purkinje neurons of mouse cerebellum. Folia morphologica. vol 55. issue 4. 1997-09-18. PMID:9243936. |
histochemical detection of dystrophin in purkinje neurons of mouse cerebellum. |
1997-09-18 |
2023-08-12 |
mouse |
| P L De Jager, J Zuo, N Heint. An approximately 1.2-Mb bacterial artificial chromosome contig refines the genetic and physical maps of the lurcher locus on mouse chromosome 6. Genome research. vol 7. issue 7. 1997-09-18. PMID:9253602. |
this symptom results from a neurodegenerative event in the cerebellum: there is a catastrophic loss of purkinje cells in the heterozygote animal between postnatal days 10 and 15. |
1997-09-18 |
2023-08-12 |
mouse |
| S H Park, S H Pepkowitz, C Kerfoot, M J De Rosa, V Poukens, R Wienecke, J E DeClue, H V Vinter. Tuberous sclerosis in a 20-week gestation fetus: immunohistochemical study. Acta neuropathologica. vol 94. issue 2. 1997-09-17. PMID:9255394. |
tuberin expression was noted in heterotopic neurons in the white matter and brain cells consistent with cajal retzius cells in the neocortical molecular layer, very weakly in superficial cortical neurons, neurons in the basal ganglia, purkinje cells and external granular cells of cerebellum, cranial nerve nuclei neurons, occasional germinal matrix cells, ependymal cells, choroid plexus epithelium, and pituitary gland neuroendocrine cells; it was not seen within the cells of subependymal nodules. |
1997-09-17 |
2023-08-12 |
Not clear |
| D B Arnold, N Heint. A calcium responsive element that regulates expression of two calcium binding proteins in Purkinje cells. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 16. 1997-09-08. PMID:9238065. |
calbindin d28 encodes a calcium binding protein that is expressed in the cerebellum exclusively in purkinje cells. |
1997-09-08 |
2023-08-12 |
Not clear |
| A R Mohn, R M Feddersen, M S Nguyen, B H Kolle. Phenotypic analysis of mice lacking the highly abundant Purkinje cell- and bipolar neuron-specific PCP2 protein. Molecular and cellular neurosciences. vol 9. issue 1. 1997-09-05. PMID:9204480. |
the purkinje cell protein-2 (pcp2, also known as l7) gene is abundantly expressed only in purkinje cells of the cerebellum and bipolar neurons of the retina. |
1997-09-05 |
2023-08-12 |
mouse |
| T Matsu. Transcriptional regulation of a Purkinje cell-specific gene through a functional interaction between ROR alpha and RAR. Genes to cells : devoted to molecular & cellular mechanisms. vol 2. issue 4. 1997-08-29. PMID:9224660. |
the orphan nuclear receptor ror alpha is highly expressed in the purkinje cells of the cerebellum during the postnatal development of brain. |
1997-08-29 |
2023-08-12 |
Not clear |
| P A Felts, S Yokoyama, S Dib-Hajj, J A Black, S G Waxma. Sodium channel alpha-subunit mRNAs I, II, III, NaG, Na6 and hNE (PN1): different expression patterns in developing rat nervous system. Brain research. Molecular brain research. vol 45. issue 1. 1997-08-27. PMID:9105672. |
in the cerebellum, sodium channel mrna i was not detected at e17 or p2, but became detectable in purkinje cells at p15 and continued to show a low level of expression in these cells at p30. |
1997-08-27 |
2023-08-12 |
rat |
| P A Felts, S Yokoyama, S Dib-Hajj, J A Black, S G Waxma. Sodium channel alpha-subunit mRNAs I, II, III, NaG, Na6 and hNE (PN1): different expression patterns in developing rat nervous system. Brain research. Molecular brain research. vol 45. issue 1. 1997-08-27. PMID:9105672. |
na6 mrna was highly expressed in the e17 cerebellum; this mrna was present at high levels in purkinje cells throughout development, although in granule cells the signal was attenuated at p15-p30. |
1997-08-27 |
2023-08-12 |
rat |
| C R Goodlett, A T Eiler. Alcohol-induced Purkinje cell loss with a single binge exposure in neonatal rats: a stereological study of temporal windows of vulnerability. Alcoholism, clinical and experimental research. vol 21. issue 4. 1997-08-20. PMID:9194933. |
a uniform random sample of sections was obtained from serial frozen sections through the cerebellum, stained with thionin, and purkinje cells were counted from a uniform random sample of locations on each section with the three-dimensional optical fractionator. |
1997-08-20 |
2023-08-12 |
rat |
| P A Doroshenko, A Woppmann, G Miljanich, G J Augustin. Pharmacologically distinct presynaptic calcium channels in cerebellar excitatory and inhibitory synapses. Neuropharmacology. vol 36. issue 6. 1997-08-18. PMID:9225314. |
we have used whole-cell patch clamp recordings and pharmacological blockers of ca channels to compare the pharmacology of ca channels that mediate synaptic transmission at the three types of synapses innervating purkinje cells in rat cerebellar slices. |
1997-08-18 |
2023-08-12 |
rat |
| M Yamada, M Mizuguchi, N Otsuka, K Ikeda, H Takahash. Ultrastructural localization of CD38 immunoreactivity in rat brain. Brain research. vol 756. issue 1-2. 1997-08-15. PMID:9187313. |
in the cerebellum, labeling was observed in several types of neuron such as granule, golgi, basket and purkinje cells. |
1997-08-15 |
2023-08-12 |
rat |
| J S King, P Madtes, G A Bishop, T L Overbec. The distribution of corticotropin-releasing factor (CRF), CRF binding sites and CRF1 receptor mRNA in the mouse cerebellum. Progress in brain research. vol 114. 1997-08-06. PMID:9193138. |
positive signal is present throughout the cerebellum in purkinje cells and the granule cell layer. |
1997-08-06 |
2023-08-12 |
mouse |