| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Merodio, J M Irache, F Eclancher, M Mirshahi, H Villarroy. Distribution of albumin nanoparticles in animals induced with the experimental allergic encephalomyelitis. Journal of drug targeting. vol 8. issue 5. 2001-07-19. PMID:11328657. |
the optic chiasma, iris and the area of the purkinje cells of the cerebellum revealed also an intense presence of these carriers. |
2001-07-19 |
2023-08-12 |
rat |
| M Doulazmi, F Frédéric, F Capone, M Becker-André, N Delhaye-Bouchaud, J Marian. A comparative study of Purkinje cells in two RORalpha gene mutant mice: staggerer and RORalpha(-/-). Brain research. Developmental brain research. vol 127. issue 2. 2001-07-19. PMID:11335003. |
to address the question whether the morphological defects in the rora(-/-) cerebellum are identical to the rora(sg/sg) one, we compared number and size of purkinje cells in both staggerer and roralpha null-mutant mice, using calbindin (cabp) immunohistochemistry and revelation of beta-gal activity. |
2001-07-19 |
2023-08-12 |
mouse |
| M Doulazmi, F Frédéric, F Capone, M Becker-André, N Delhaye-Bouchaud, J Marian. A comparative study of Purkinje cells in two RORalpha gene mutant mice: staggerer and RORalpha(-/-). Brain research. Developmental brain research. vol 127. issue 2. 2001-07-19. PMID:11335003. |
in rora(-/-) mouse, all the the beta-gal-positive purkinje cells also expressed cabp, but the cerebellum contained 78% less cabp-positive cells than control, a deficit not different from the one observed in rora(sg/sg). |
2001-07-19 |
2023-08-12 |
mouse |
| X Z Sun, Y N Harada, S Takahashi, N Shiomi, T Shiom. Purkinje cell degeneration in mice lacking the xeroderma pigmentosum group G gene. Journal of neuroscience research. vol 64. issue 4. 2001-07-19. PMID:11340641. |
these results indicated a marked degeneration of purkinje cells in the xpg mutant cerebellum. |
2001-07-19 |
2023-08-12 |
mouse |
| R Wehrlé, P Caroni, C Sotelo, I Dusar. Role of GAP-43 in mediating the responsiveness of cerebellar and precerebellar neurons to axotomy. The European journal of neuroscience. vol 13. issue 5. 2001-07-12. PMID:11264659. |
furthermore, mature purkinje cells in cerebellar explants of transgenic mice that overexpress gap-43 do not regenerate after axotomy, even in the presence of a permissive substrate (cerebellar embryonic tissue) and, contrary to the case in wild-type mice, they do not survive in the in vitro conditions and undergo massive cell death. |
2001-07-12 |
2023-08-12 |
mouse |
| Y Sekine-Aizawa, E Hama, K Watanabe, S Tsubuki, M Kanai-Azuma, Y Kanai, H Arai, H Aizawa, N Iwata, T C Said. Matrix metalloproteinase (MMP) system in brain: identification and characterization of brain-specific MMP highly expressed in cerebellum. The European journal of neuroscience. vol 13. issue 5. 2001-07-12. PMID:11264666. |
in cerebellum, its expression was regulated developmentally and was closely associated with dendritic tree formation of purkinje cells, suggesting that mt5-mmp may contribute to neuronal development. |
2001-07-12 |
2023-08-12 |
rat |
| Y Sugaya, Y Sasaki, Y Goshima, K Kitahama, T Kusakabe, T Miyamae, T Kato, Y Mis. Autoradiographic studies using L-[(14)C]DOPA and L-DOPA reveal regional Na(+)-dependent uptake of the neurotransmitter candidate L-DOPA in the CNS. Neuroscience. vol 104. issue 1. 2001-07-12. PMID:11311526. |
in the cerebellum, grains formed in clusters surrounding the purkinje cells. |
2001-07-12 |
2023-08-12 |
rat |
| C L Armstrong, A M Krueger-Naug, R W Currie, R Hawke. Constitutive expression of heat shock protein HSP25 in the central nervous system of the developing and adult mouse. The Journal of comparative neurology. vol 434. issue 3. 2001-07-12. PMID:11331528. |
during development, hsp25 is transiently expressed in neurons of the inferior colliculus, various thalamic subnuclei, and the majority of purkinje cells in the cerebellum. |
2001-07-12 |
2023-08-12 |
mouse |
| K J Sweeney, A Prokscha, G Eichel. NudE-L, a novel Lis1-interacting protein, belongs to a family of vertebrate coiled-coil proteins. Mechanisms of development. vol 101. issue 1-2. 2001-07-05. PMID:11231056. |
we show that mnude-l and mlis1 are coexpressed in the postnatal and adult cerebral cortices and in the purkinje neurons of the cerebellum. |
2001-07-05 |
2023-08-12 |
mouse |
| M Muñoz, A Martínez, F Cuttitta, A Gonzále. Distribution of adrenomedullin-like immunoreactivity in the central nervous system of the frog. Journal of chemical neuroanatomy. vol 21. issue 2. 2001-07-05. PMID:11312053. |
strikingly, purkinje cells in the cerebellum also showed am immunoreactivity, albeit not all of these cells were equally stained. |
2001-07-05 |
2023-08-12 |
human |
| T Liu, T Zwingman, R Li, T Pan, B S Wong, R B Petersen, P Gambetti, K Herrup, M S S. Differential expression of cellular prion protein in mouse brain as detected with multiple anti-PrP monoclonal antibodies. Brain research. vol 896. issue 1-2. 2001-06-28. PMID:11277980. |
although expression of prp(c) has been reported to be required for long-term survival of purkinje cells, we were unable to detect prp(c) in the purkinje cell layer in the cerebellum with multiple anti-prp mabs. |
2001-06-28 |
2023-08-12 |
mouse |
| T Sato, T S Wilson, L F Hughes, H R Konrad, M Nakayama, R H Helfer. Age-related changes in levels of tyrosine kinase B receptor and fibroblast growth factor receptor 2 in the rat inferior colliculus: implications for neural senescence. Neuroscience. vol 103. issue 3. 2001-06-21. PMID:11274788. |
in the cerebellum, the somata and dendrites of the purkinje cells were also immunolabeled.a significant reduction in levels of the full-length form of tyrosine kinase b receptor in 18- and 25-month-old rats (respectively, approximately 20% and 30% relative to 3-month-olds) was revealed using western blot analyses. |
2001-06-21 |
2023-08-12 |
rat |
| C F Ekerot, H Jörntel. Parallel fibre receptive fields of Purkinje cells and interneurons are climbing fibre-specific. The European journal of neuroscience. vol 13. issue 7. 2001-06-21. PMID:11298790. |
in cats decerebrated at the intercollicular level, the cutaneous parallel fibre receptive fields of purkinje cells, molecular layer interneurons and golgi cells in the cerebellar c3 zone were delineated by natural stimulation of the skin during extracellular unitary recordings. |
2001-06-21 |
2023-08-12 |
Not clear |
| C Sur, K A Wafford, D S Reynolds, K L Hadingham, F Bromidge, A Macaulay, N Collinson, G O'Meara, O Howell, R Newman, J Myers, J R Atack, G R Dawson, R M McKernan, P J Whiting, T W Rosah. Loss of the major GABA(A) receptor subtype in the brain is not lethal in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 10. 2001-06-21. PMID:11331371. |
purkinje cells of the cerebellum primarily express alpha1beta2gamma2 receptors, and in electrophysiological recordings from alpha1-/- mice gaba currents in these neurons are dramatically reduced, and residual currents have a benzodiazepine pharmacology characteristic of alpha2- or alpha3-containing receptors. |
2001-06-21 |
2023-08-12 |
mouse |
| H Hira. Modification of AMPA receptor clustering regulates cerebellar synaptic plasticity. Neuroscience research. vol 39. issue 3. 2001-06-14. PMID:11248365. |
this article focuses on molecular mechanisms regulating the synaptic ampa receptor clustering in purkinje cells, which could underlie the expression of cerebellar ltd. synaptic ampa receptor clusters in dendritic spines of purkinje cells are disrupted upon protein kinase c (pkc)-mediated phosphorylation of serine 880 in the c-terminal domain of glur2. |
2001-06-14 |
2023-08-12 |
Not clear |
| K L Quick, L L Duga. Superoxide stress identifies neurons at risk in a model of ataxia-telangiectasia. Annals of neurology. vol 49. issue 5. 2001-06-14. PMID:11357953. |
however, the hallmark of a-t is fulminant degeneration of cerebellar purkinje cells accompanied by a progressive ataxia with features of both cerebellar and basal ganglia dysfunction. |
2001-06-14 |
2023-08-12 |
mouse |
| B Teubner, B Odermatt, M Guldenagel, G Sohl, J Degen, F Bukauskas, J Kronengold, V K Verselis, Y T Jung, C A Kozak, K Schilling, K Willeck. Functional expression of the new gap junction gene connexin47 transcribed in mouse brain and spinal cord neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 4. 2001-06-07. PMID:11160382. |
in situ hybridizations demonstrated high expression in alpha motor neurons of the spinal cord, pyramidal cells of the cortex and hippocampus, granular and molecular layers of the dentate gyrus, and purkinje cells of the cerebellum as well as several nuclei of the brainstem. |
2001-06-07 |
2023-08-12 |
mouse |
| R Anadón, I Rodríguez Moldes, P Carpintero, G Evangelatos, E Livianou, L Leondiadis, I Quintela, M C Cerviño, J Gómez-Márque. Differential expression of thymosins beta(4) and beta(10) during rat cerebellum postnatal development. Brain research. vol 894. issue 2. 2001-06-07. PMID:11251199. |
in the young (7 and 18 postnatal days) and adult (1 and 4 months old) rat cerebellum, tbeta(4) was mainly expressed in the glia (microglia, golgi epithelial cells and oligodendrocytes), neurons (granule cells and purkinje cells), and in the capillaries. |
2001-06-07 |
2023-08-12 |
rat |
| b' S Pons, J L Trejo, J R Mart\\xc3\\xadnez-Morales, E Mart\\xc3\\xa. Vitronectin regulates Sonic hedgehog activity during cerebellum development through CREB phosphorylation. Development (Cambridge, England). vol 128. issue 9. 2001-06-07. PMID:11290288.' |
during development of the cerebellum, sonic hedgehog (shh) is expressed in migrating and settled purkinje neurons and is directly responsible for proliferation of granule cell precursors in the external germinal layer. |
2001-06-07 |
2023-08-12 |
Not clear |
| A W McGee, J R Topinka, K Hashimoto, R S Petralia, S Kakizawa, F W Kauer, A Aguilera-Moreno, R J Wenthold, M Kano, D S Bredt, F Kaue. PSD-93 knock-out mice reveal that neuronal MAGUKs are not required for development or function of parallel fiber synapses in cerebellum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 9. 2001-06-07. PMID:11312293. |
despite the absence of maguk immunoreactivity in purkinje neurons from the knock-outs, these mice have no structural or functional abnormality in cerebellum. |
2001-06-07 |
2023-08-12 |
mouse |