| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eijun Nishihara, Hiromi Yoshida-Komiya, Chi-Shing Chan, Lan Liao, Ronald L Davis, Bert W O'Malley, Jianming X. SRC-1 null mice exhibit moderate motor dysfunction and delayed development of cerebellar Purkinje cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 1. 2003-01-27. PMID:12514218. |
in the adult cerebellum, purkinje cells (pcs) preferentially express src-1 over src-2, but src-2 mrna is slightly elevated in the src-1(-)/- pcs. |
2003-01-27 |
2023-08-12 |
mouse |
| Spencer L Smith, Thomas S Oti. Persistent changes in spontaneous firing of Purkinje neurons triggered by the nitric oxide signaling cascade. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 2. 2003-01-24. PMID:12533595. |
we tested for modulation of spontaneous firing of purkinje neurons in cerebellar slices under conditions in which principal synaptic inputs were blocked. |
2003-01-24 |
2023-08-12 |
Not clear |
| Mary Womack, Kamran Khodakha. Active contribution of dendrites to the tonic and trimodal patterns of activity in cerebellar Purkinje neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 24. 2003-01-23. PMID:12486152. |
an understanding of cerebellar timing requires an appreciation of the intrinsic firing behavior of purkinje cells and the extent to which their activity is regulated within the functional circuits. |
2003-01-23 |
2023-08-12 |
Not clear |
| Mary Womack, Kamran Khodakha. Active contribution of dendrites to the tonic and trimodal patterns of activity in cerebellar Purkinje neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 24. 2003-01-23. PMID:12486152. |
we have examined the spontaneous firing of purkinje neurons in isolation from the rest of the cerebellar circuitry by blocking fast synaptic transmission in acutely prepared cerebellar slices. |
2003-01-23 |
2023-08-12 |
Not clear |
| Raquel Riquelme, Celia P Miralles, Angel L De Bla. Bergmann glia GABA(A) receptors concentrate on the glial processes that wrap inhibitory synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 24. 2003-01-23. PMID:12486165. |
we studied the cellular and subcellular distribution of gaba(a) receptors in the bergmann glia and purkinje cells in the molecular layer of the cerebellum by using electron microscopy postembedding immunogold techniques. |
2003-01-23 |
2023-08-12 |
Not clear |
| Georgia A Bisho. Development of a corticotropin-releasing factor-mediated effect on the firing rate of Purkinje cells in the postnatal mouse cerebellum. Experimental neurology. vol 178. issue 2. 2003-01-21. PMID:12504876. |
development of a corticotropin-releasing factor-mediated effect on the firing rate of purkinje cells in the postnatal mouse cerebellum. |
2003-01-21 |
2023-08-12 |
mouse |
| Georgia A Bisho. Development of a corticotropin-releasing factor-mediated effect on the firing rate of Purkinje cells in the postnatal mouse cerebellum. Experimental neurology. vol 178. issue 2. 2003-01-21. PMID:12504876. |
corticotropin-releasing factor (crf), present in climbing and mossy fiber afferents to the adult mouse cerebellum, acts as a neuromodulator to enhance the spontaneous and amino-acid-induced firing rate of purkinje cells. |
2003-01-21 |
2023-08-12 |
mouse |
| Georgia A Bisho. Development of a corticotropin-releasing factor-mediated effect on the firing rate of Purkinje cells in the postnatal mouse cerebellum. Experimental neurology. vol 178. issue 2. 2003-01-21. PMID:12504876. |
taken together, these immunohistochemical observations and the present physiologic data indicate that crf does not modulate the activity of purkinje cells until the peptide begins to assume an adult-like distribution in cerebellar afferents. |
2003-01-21 |
2023-08-12 |
mouse |
| Stéphane Genet, Bruno Delor. A biophysical model of nonlinear dynamics underlying plateau potentials and calcium spikes in purkinje cell dendrites. Journal of neurophysiology. vol 88. issue 5. 2003-01-14. PMID:12424284. |
computational capabilities of purkinje cells (pcs) are central to the cerebellum function. |
2003-01-14 |
2023-08-12 |
Not clear |
| Hiroaki Fujii, Tomoo Hiran. Calcineurin regulates induction of late phase of cerebellar long-term depression in rat cultured Purkinje neurons. The European journal of neuroscience. vol 16. issue 9. 2003-01-13. PMID:12431231. |
calcineurin regulates induction of late phase of cerebellar long-term depression in rat cultured purkinje neurons. |
2003-01-13 |
2023-08-12 |
rat |
| Shinji Matsuda, Michisuke Yuzak. Mutation in hotfoot-4J mice results in retention of delta2 glutamate receptors in ER. The European journal of neuroscience. vol 16. issue 8. 2003-01-08. PMID:12405964. |
the orphan glutamate receptor delta2 is selectively expressed in purkinje cells and plays a critical role in cerebellar function. |
2003-01-08 |
2023-08-12 |
mouse |
| Mohamed Doulazmi, Nadia Hadj-Sahraoui, Florence Frederic, Jean Marian. Diminishing Purkinje cell populations in the cerebella of aging heterozygous Purkinje cell degeneration but not heterozygous nervous mice. Journal of neurogenetics. vol 16. issue 2. 2003-01-06. PMID:12479378. |
mice homozygous for the recessive, cerebellar affected mutations nervous and purkinje cell degeneration display an almost complete loss of purkinje cells during their first two postnatal months. |
2003-01-06 |
2023-08-12 |
mouse |
| C Spilker, E D Gundelfinger, K-H Braunewel. Evidence for different functional properties of the neuronal calcium sensor proteins VILIP-1 and VILIP-3: from subcellular localization to cellular function. Biochimica et biophysica acta. vol 1600. issue 1-2. 2002-12-31. PMID:12445467. |
our data indicate that vilip-3, which is mainly expressed in purkinje cells, and vilip-1, which is expressed in granule cells in the cerebellum, show a different calcium-dependent subcellular localization, may activate different cellular signaling pathways, and thus have signaling functions which seem to be cell-type specific. |
2002-12-31 |
2023-08-12 |
Not clear |
| Mary D Womack, Kamran Khodakha. Characterization of large conductance Ca2+-activated K+ channels in cerebellar Purkinje neurons. The European journal of neuroscience. vol 16. issue 7. 2002-12-30. PMID:12405981. |
block of bk channels by iberiotoxin reduced the afterhyperpolarization of spontaneous action potentials in purkinje neurons in acutely prepared cerebellar slices. |
2002-12-30 |
2023-08-12 |
Not clear |
| K G Rottach, W A Wohlgemuth, A E Dzaja, T Eggert, A Straub. Effects of intravenous opioids on eye movements in humans: possible mechanisms. Journal of neurology. vol 249. issue 9. 2002-12-27. PMID:12242539. |
on the basis of the clinical findings and of recent diprenorphine pet findings in humans, which detected opiod binding sites in the cerebellum and the known inhibitory action of opiates, we hypothesized that a cerebellar dysfunction occurs after opiate administration which could possibly be mediated by inhibition of the parallel fiber activation of the purkinje cells. |
2002-12-27 |
2023-08-12 |
human |
| Pauline Cavelier, Huguette Beekenkamp, Hee-Sup Shin, Kisun Jun, Jean-Louis Boss. Cerebellar slice cultures from mice lacking the P/Q calcium channel: electroresponsiveness of Purkinje cells. Neuroscience letters. vol 333. issue 1. 2002-12-26. PMID:12401561. |
cerebellar slice cultures from mice lacking the p/q calcium channel: electroresponsiveness of purkinje cells. |
2002-12-26 |
2023-08-12 |
mouse |
| Pauline Cavelier, Huguette Beekenkamp, Hee-Sup Shin, Kisun Jun, Jean-Louis Boss. Cerebellar slice cultures from mice lacking the P/Q calcium channel: electroresponsiveness of Purkinje cells. Neuroscience letters. vol 333. issue 1. 2002-12-26. PMID:12401561. |
to investigate the role of p/q type ca(2+) channels in determining the firing pattern of purkinje cells (pcs) we compared the somatically evoked discharge of action potentials (aps) in pcs from 3 to 4 week old cerebellar slice cultures obtained with ataxic mice lacking alpha(1a)-subunit (alpha(-/-)) and with normal mice (non-ataxic alpha(+/-) or alpha(+/+)) using the whole-cell configuration of the patch-clamp recording method. |
2002-12-26 |
2023-08-12 |
mouse |
| Minoru Takase, Kazuyoshi Ukena, Kazuyoshi Tsutsu. Expression and localization of cytochrome P450(11beta,aldo) mRNA in the frog brain. Brain research. vol 950. issue 1-2. 2002-12-23. PMID:12231255. |
in situ hybridization analysis showed that the p450(11beta,aldo) gene was transcribed abundantly in the cells throughout the frog brain, such as the pallium mediale in the telencephalon, the nucleus preopticus in the diencephalon, the stratum griseum superficiale tecti in the midbrain, and purkinje cells in the cerebellum. |
2002-12-23 |
2023-08-12 |
Not clear |
| Kunihiro Sakuma, Kimi Watanabe, Tsuyoshi Totsuka, Mamoru Sano, Hiroshi Nakano, Ryuta Nakao, Jun-Ji Nishikawa, Yoshihide Sorimachi, Kanji Yoshimoto, Masahiro Yasuhar. The reciprocal change of neurotrophin-4 and glial cell line-derived neurotrophic factor protein in the muscles, spinal cord and cerebellum of the dy mouse. Acta neuropathologica. vol 104. issue 5. 2002-12-23. PMID:12410396. |
in the dy mice, the microtubule-associated protein-2 (map-2) protein level was markedly decreased in the purkinje and granule cells of the cerebellum, and in lumbar motoneurons of the spinal cord. |
2002-12-23 |
2023-08-12 |
mouse |
| Kunihiro Sakuma, Kimi Watanabe, Tsuyoshi Totsuka, Mamoru Sano, Hiroshi Nakano, Ryuta Nakao, Jun-Ji Nishikawa, Yoshihide Sorimachi, Kanji Yoshimoto, Masahiro Yasuhar. The reciprocal change of neurotrophin-4 and glial cell line-derived neurotrophic factor protein in the muscles, spinal cord and cerebellum of the dy mouse. Acta neuropathologica. vol 104. issue 5. 2002-12-23. PMID:12410396. |
in dy mice, gdnf was markedly enhanced in the purkinje and granule cells of the cerebellum, in many lumbar motoneurons, and in the regenerating atrophied fibers. |
2002-12-23 |
2023-08-12 |
mouse |