| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Melanie M Das, Pablo Avalos, Patrick Suezaki, Marlesa Godoy, Leslie Garcia, Christine D Chang, Jean-Philippe Vit, Brandon Shelley, Genevieve Gowing, Clive N Svendse. Human neural progenitors differentiate into astrocytes and protect motor neurons in aging rats. Experimental neurology. vol 280. 2017-04-28. PMID:27032721. |
we also transplanted hnpcs genetically modified to secrete glial cell line-derived neurotrophic factor (gdnf) into the aging rat spinal cord, as this combination of cell and protein delivery can protect motor neurons in animal models of als. |
2017-04-28 |
2023-08-13 |
human |
| Nicolina Cristina Sorrentino, Veronica Maffia, Sandra Strollo, Vincenzo Cacace, Noemi Romagnoli, Anna Manfredi, Domenico Ventrella, Francesco Dondi, Francesca Barone, Massimo Giunti, Anne-Renee Graham, Yan Huang, Susan L Kalled, Alberto Auricchio, Maria Laura Bacci, Enrico Maria Surace, Alessandro Frald. A Comprehensive Map of CNS Transduction by Eight Recombinant Adeno-associated Virus Serotypes Upon Cerebrospinal Fluid Administration in Pigs. Molecular therapy : the journal of the American Society of Gene Therapy. vol 24. issue 2. 2016-11-09. PMID:26639405. |
moreover, raav9 robustly transduced both glia and neurons, including the motor neurons of the spinal cord. |
2016-11-09 |
2023-08-13 |
human |
| C Sámano, J Kaur, A Nistr. A study of methylprednisolone neuroprotection against acute injury to the rat spinal cord in vitro. Neuroscience. vol 315. 2016-10-19. PMID:26701292. |
we investigated if mpss could protect spinal neurons and glia using an in vitro model of the rat spinal cord that enables recording reflexes, fictive locomotion and morphological analysis of damage. |
2016-10-19 |
2023-08-13 |
rat |
| Young Chan Jeong, Ji Seon Son, Young Bae Kwo. The spinal antinociceptive mechanism determined by systemic administration of BD1047 in zymosan-induced hyperalgesia in rats. Brain research bulletin. vol 119. issue Pt A. 2016-08-29. PMID:26434709. |
in the spinal cord section, sig-1r immunoreactivity was exclusively distributed in both spinal dorsal horn neurons and central endings of unmyelinated primary afferent fibers but not in glia. |
2016-08-29 |
2023-08-13 |
rat |
| Norianne T Ingram, Rana R Khankan, Patricia E Phelp. Olfactory Ensheathing Cells Express α7 Integrin to Mediate Their Migration on Laminin. PloS one. vol 11. issue 4. 2016-08-26. PMID:27078717. |
the unique glia located in the olfactory system, called olfactory ensheathing cells (oecs), are implicated as an attractive choice for transplantation therapy following spinal cord injury because of their pro-regenerative characteristics. |
2016-08-26 |
2023-08-13 |
Not clear |
| Adam K Walker, Krista J Spiller, Guanghui Ge, Allen Zheng, Yan Xu, Melissa Zhou, Kalyan Tripathy, Linda K Kwong, John Q Trojanowski, Virginia M-Y Le. Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43. Acta neuropathologica. vol 130. issue 5. 2016-08-11. PMID:26197969. |
accumulation of phosphorylated cytoplasmic tdp-43 inclusions accompanied by loss of normal nuclear tdp-43 in neurons and glia of the brain and spinal cord are the molecular hallmarks of amyotrophic lateral sclerosis (als) and frontotemporal lobar degeneration (ftld-tdp). |
2016-08-11 |
2023-08-13 |
mouse |
| Chao Zhang, Anna Y Morozova, Maxim A Abakumov, Ilya L Gubsky, Patricia Douglas, Shiqing Feng, Andrey S Bryukhovetskiy, Vladimir P Chekhoni. Precise Delivery Into Chronic Spinal Cord Injury Syringomyelic Cysts with Magnetic Nanoparticles MRI Visualization. Medical science monitor : international medical journal of experimental and clinical research. vol 21. 2016-08-02. PMID:26486048. |
traumatic spinal cord injury (sci) often results in the deficiency of glia and neurons in cystic cavities. |
2016-08-02 |
2023-08-13 |
Not clear |
| Frederik Seibt, Rémy Schlichte. Noradrenaline-mediated facilitation of inhibitory synaptic transmission in the dorsal horn of the rat spinal cord involves interlaminar communications. The European journal of neuroscience. vol 42. issue 9. 2016-07-27. PMID:26370319. |
short-term pretreatment of intact spinal cord slices with the glial cell metabolism inhibitor fluorocitrate or pharmacological blockade of ionotropic glutamate and atp receptors mimicked the consequences of a mechanical transection between laminae iv and v. taken together, the current results indicate that the facilitation of inhibitory synaptic transmission in laminae iii-iv of the dh by na requires functional interlaminar connections between deep and more superficial laminae, and might strongly depend on glia to neuron interactions. |
2016-07-27 |
2023-08-13 |
rat |
| M Meyer, M C Gonzalez Deniselle, L Garay, R Sitruk-Ware, R Guennoun, M Schumacher, A F De Nicol. The progesterone receptor agonist Nestorone holds back proinflammatory mediators and neuropathology in the wobbler mouse model of motoneuron degeneration. Neuroscience. vol 308. 2016-07-19. PMID:26349009. |
wobbler mutant mice suffer from progressive motoneuron degeneration and glial cell reactivity in the spinal cord. |
2016-07-19 |
2023-08-13 |
mouse |
| Wenli Chen, Houqing Lon. [Role of matrix metalloproteinases in regulating neurovascular unit affect the prognosis of chronic compression of spinal cord injury: current status]. Zhonghua wai ke za zhi [Chinese journal of surgery]. vol 53. issue 9. 2016-07-12. PMID:26654153. |
this paper discusses matrix metalloproteinase (mmp) impact on the stability of the neural vascular unit, by directly decomposing extracellular matrix, inducing the glial cell migration, activating angiogenesis, regulating function of blood spinal cord barrier, and put forward the mmp may be the key points in regulation of spinal cord neurovascular unit structure and function change to affect the outcome of chronic oppressive cervical spinal cord. |
2016-07-12 |
2023-08-13 |
Not clear |
| Yehui Liao, Dejun Zhong, Min Kang, Shuaihui Yao, Yi Zhang, Yongtao Y. [TRANSPLANTATION OF NEURAL STEM CELLS INDUCED BY ALL-TRANS- RETINOIC ACID COMBINED WITH GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR AND CHONDROITINASE ABC FOR REPAIRING SPINAL CORD INJURY OF RATS]. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery. vol 29. issue 8. 2016-07-12. PMID:26677625. |
[transplantation of neural stem cells induced by all-trans- retinoic acid combined with glial cell line derived neurotrophic factor and chondroitinase abc for repairing spinal cord injury of rats]. |
2016-07-12 |
2023-08-13 |
rat |
| Yehui Liao, Dejun Zhong, Min Kang, Shuaihui Yao, Yi Zhang, Yongtao Y. [TRANSPLANTATION OF NEURAL STEM CELLS INDUCED BY ALL-TRANS- RETINOIC ACID COMBINED WITH GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR AND CHONDROITINASE ABC FOR REPAIRING SPINAL CORD INJURY OF RATS]. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery. vol 29. issue 8. 2016-07-12. PMID:26677625. |
to observe the effect of transplantation of neural stem cells (nscs) induced by all-trans-retinoic acid (atra) combined with glial cell line derived neurotrophic factor (gdnf) and chondroitinase abc (chabc) on the neurological functional recovery of injured spinal cord in sprague dawley (sd) rats. |
2016-07-12 |
2023-08-13 |
rat |
| Cui'e Lu, Yue Liu, Bei Sun, Yu'e Sun, Bailing Hou, Yu Zhang, Zhengliang Ma, Xiaoping G. Intrathecal Injection of JWH-015 Attenuates Bone Cancer Pain Via Time-Dependent Modification of Pro-inflammatory Cytokines Expression and Astrocytes Activity in Spinal Cord. Inflammation. vol 38. issue 5. 2016-06-24. PMID:25896633. |
intra-tibia inoculation of walker 256 mammary gland carcinoma cells induced progressive bone cancer pain; a long-term up-regulation of il-1β, il-6, il-18, and tnf-α; and the activation of glia in spinal cord. |
2016-06-24 |
2023-08-13 |
rat |
| Bahareh Amin, Ehsan Poureshagh, Hossein Hosseinzade. The Effect of Verbascoside in Neuropathic Pain Induced by Chronic Constriction Injury in Rats. Phytotherapy research : PTR. vol 30. issue 1. 2016-06-21. PMID:26537351. |
spinal cord levels of apoptotic factors and glia markers were quantified on days 3, 7, and 14 post-cci. |
2016-06-21 |
2023-08-13 |
rat |
| Shoei Furukaw. [Basic Research on Neurotrophic Factors and Its Application to Medical Uses]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 135. issue 11. 2016-06-13. PMID:26521870. |
in addition, my laboratory discovered that endogenous glial cell line-derived neurotrophic factor (gdnf) contributes to the amelioration of motor activity after spinal cord injury. |
2016-06-13 |
2023-08-13 |
Not clear |
| Klaudia Kwiatkowski, Anna Piotrowska, Ewelina Rojewska, Wioletta Makuch, Agnieszka Jurga, Joanna Slusarczyk, Ewa Trojan, Agnieszka Basta-Kaim, Joanna Mik. Beneficial properties of maraviroc on neuropathic pain development and opioid effectiveness in rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 64. 2016-05-31. PMID:26190414. |
to investigate the mechanism of action of maraviroc, we measured the expression of glial cell markers, ccr5 and certain ccr5 ligands (ccl3, ccl4, ccl5, ccl7, ccl11), in the spinal cord and dorsal root ganglia (drg) of vehicle- and maraviroc-treated, cci-exposed rats. |
2016-05-31 |
2023-08-13 |
rat |
| M Kimura, A Sakai, A Sakamoto, H Suzuk. Glial cell line-derived neurotrophic factor-mediated enhancement of noradrenergic descending inhibition in the locus coeruleus exerts prolonged analgesia in neuropathic pain. British journal of pharmacology. vol 172. issue 10. 2016-05-24. PMID:25572945. |
glial cell line-derived neurotrophic factor (gdnf), a well-established neurotrophic factor for noradrenergic neurons, is a major pain modulator in the spinal cord and primary sensory neurons. |
2016-05-24 |
2023-08-13 |
Not clear |
| William Galbavy, Martin Kaczocha, Michelino Puopolo, Lixin Liu, Mario J Rebecch. Neuroimmune and Neuropathic Responses of Spinal Cord and Dorsal Root Ganglia in Middle Age. PloS one. vol 10. issue 8. 2016-05-10. PMID:26241743. |
unlike the spinal cord, marker expression profiles in naïve drg were unchanged across age (except increased atf3); whereas, levels of gfap protein, localized to satellite glia, were highly elevated in middle age, but independent of nerve injury. |
2016-05-10 |
2023-08-13 |
rat |
| L Guo, Z X Quan, Z H Zhao, K Tang, Y S Ou, D M Jian. Effects of musk ketone on nerve recovery after spinal cord injury. Genetics and molecular research : GMR. vol 14. issue 2. 2016-04-21. PMID:25966058. |
he staining showed that in the ns group, there was hemorrhage, edema, necrosis, axonal demyelination, inflammatory cell infiltration and glial cell response in spinal cord tissue. |
2016-04-21 |
2023-08-13 |
rat |
| Yimin Yuan, Feng Zhu, Yingyan Pu, Dan Wang, Aijun Huang, Xin Hu, Shangyao Qin, Xiu Sun, Zhida Su, Cheng H. Neuroprotective effects of nitidine against traumatic CNS injury via inhibiting microglia activation. Brain, behavior, and immunity. vol 48. 2016-04-13. PMID:25900440. |
glial cell response to injury has been well documented in the pathogenesis after traumatic brain injury (tbi) and spinal cord injury (sci). |
2016-04-13 |
2023-08-13 |
mouse |