Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Fernando Cruz-Mendoza, Sonia Luquin, Joaquín García-Estrada, David Fernández-Quezada, Fernando Jauregui-Huert. Acoustic Stress Induces Opposite Proliferative/Transformative Effects in Hippocampal Glia. International journal of molecular sciences. vol 24. issue 6. 2023-03-29. PMID:36982594. |
acoustic stress induces opposite proliferative/transformative effects in hippocampal glia. |
2023-03-29 |
2023-08-14 |
rat |
Vilasagaram Srinivas, Saikanth Varma, Suryam Reddy Kona, Ahamed Ibrahim, Asim K Duttaroy, Sanjay Basa. Dietary omega-3 fatty acid deficiency from pre-pregnancy to lactation affects expression of genes involved in hippocampal neurogenesis of the offspring. Prostaglandins, leukotrienes, and essential fatty acids. vol 191. 2023-03-16. PMID:36924605. |
among the genes involved in neurogenesis, the expression of brain-specific tenascin-r (tnr) was downregulated to a greater extent (∼31 fold), followed by adenosine a2a receptor (a2aar), dopamine receptor d2 (drd2), glial cell line-derived neurotrophic factor (gdnf) expression in the n-3 pufa deficient hippocampus. |
2023-03-16 |
2023-08-14 |
mouse |
Owen Davis Sander. Virus-Like Cytosolic and Cell-Free Oxidatively Damaged Nucleic Acids Likely Drive Inflammation, Synapse Degeneration, and Neuron Death in Alzheimer's Disease. Journal of Alzheimer's disease reports. vol 7. issue 1. 2023-02-10. PMID:36761106. |
cytosolic oxidatively-damaged mitochondrial dna accumulated outside mitochondria dose-dependently in preclinical ad and ad patients' hippocampal neurons, and in ad patients' neocortical neurons but not cerebellar neurons or glia. |
2023-02-10 |
2023-08-14 |
mouse |
Drew L Sellers, Kunwoo Lee, Niren Murthy, Suzie H Pu. TAxI-peptide targeted Cas12a ribonuclease protein nanoformulations increase genome editing in hippocampal neurons. Journal of controlled release : official journal of the Controlled Release Society. 2023-01-03. PMID:36596342. |
taxi-rnp nanoparticles also increased genome editing efficacy in hippocampal neurons versus glia. |
2023-01-03 |
2023-08-14 |
mouse |
Caterina Gasperini, Kiril Tuntevski, Silvia Beatini, Roberta Pelizzoli, Amanda Lo Van, Damiano Mangoni, Rosa M Cossu, Giovanni Pascarella, Paolo Bianchini, Pascal Bielefeld, Margherita Scarpato, Meritxell Pons-Espinal, Remo Sanges, Alberto Diaspro, Carlos P Fitzsimons, Piero Carninci, Stefano Gustincich, Davide De Pietri Tonell. Piwil2 (Mili) sustains neurogenesis and prevents cellular senescence in the postnatal hippocampus. EMBO reports. 2022-12-06. PMID:36472244. |
depletion of mili and pirnas in the adult hippocampus impairs anpc differentiation toward a neural fate, induces senescence, and generates reactive glia. |
2022-12-06 |
2023-08-14 |
mouse |
Gonçalo Garcia, Sara Pinto, Sofia Ferreira, Daniela Lopes, Maria João Serrador, Adelaide Fernandes, Ana Rita Vaz, Alexandre de Mendonça, Frank Edenhofer, Tarja Malm, Jari Koistinaho, Dora Brite. Emerging Role of miR-21-5p in Neuron-Glia Dysregulation and Exosome Transfer Using Multiple Models of Alzheimer's Disease. Cells. vol 11. issue 21. 2022-11-11. PMID:36359774. |
here, we show glial cell activation and mir-21 overexpression in mouse organotypic hippocampal slices transplanted with sh-sy5y cells expressing the human |
2022-11-11 |
2023-08-14 |
mouse |
Wei Liu, Jiaxi Liu, Jie Gao, Xiaoxu Duan, Lifeng Zhan. Effects of Subchronic Aluminum Exposure on Learning, Memory, and Neurotrophic Factors in Rats. Neurotoxicity research. 2022-11-07. PMID:36342585. |
with hematoxylin and eosin staining, western blot, immunofluorescence, and rt-pcr, the morphology of nerve cells in the hippocampus of rat brain were observed, and the levels of activator protein-1 (ap-1) gene and protein, nerve growth factor (ngf), neurotrophin-3 (nt3), glial cell line-derived neurotrophic factor (gdnf), and brain-derived neurotrophic factor (bdnf) gene and protein level, etc. |
2022-11-07 |
2023-08-14 |
human |
Yijing Su, Yi Zhou, Mariko L Bennett, Shiying Li, Marc Carceles-Cordon, Lu Lu, Sooyoung Huh, Dennisse Jimenez-Cyrus, Benjamin C Kennedy, Sudha K Kessler, Angela N Viaene, Ingo Helbig, Xiaosong Gu, Joel E Kleinman, Thomas M Hyde, Daniel R Weinberger, David W Nauen, Hongjun Song, Guo-Li Min. A single-cell transcriptome atlas of glial diversity in the human hippocampus across the postnatal lifespan. Cell stem cell. vol 29. issue 11. 2022-11-04. PMID:36332572. |
the molecular diversity of glia in the human hippocampus and their temporal dynamics over the lifespan remain largely unknown. |
2022-11-04 |
2023-08-14 |
human |
Lamis Chamas, Isabelle Seugnet, Roseline Poirier, Marie-Stéphanie Clerget-Froidevaux, Valérie Enderli. A Fine Regulation of the Hippocampal Thyroid Signalling Protects Hypothyroid Mice against Glial Cell Activation. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36233235. |
a fine regulation of the hippocampal thyroid signalling protects hypothyroid mice against glial cell activation. |
2022-10-14 |
2023-08-14 |
mouse |
Lamis Chamas, Isabelle Seugnet, Roseline Poirier, Marie-Stéphanie Clerget-Froidevaux, Valérie Enderli. A Fine Regulation of the Hippocampal Thyroid Signalling Protects Hypothyroid Mice against Glial Cell Activation. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36233235. |
local reduced levels of thyroid hormones (ths) may impair glia morphology and activity, and promote the increase of pro-inflammatory cytokine levels mainly in the hippocampus. |
2022-10-14 |
2023-08-14 |
mouse |
Mitsuhiro Oishi, Passlick Stefan, Yoshihiko Yamazaki, Miyuki Unekawa, Ruka Adachi, Mayumi Yamada, Itaru Imayoshi, Yoshifumi Abe, Christian Steinhäuser, Kenji F Tanak. Separate optogenetic manipulation of Nerve/glial antigen 2 (NG2) glia and mural cells using the NG2 promoter. Glia. 2022-09-27. PMID:36165697. |
chr2-mediated depolarization was observed in ng2 glia in acute hippocampal slices. |
2022-09-27 |
2023-08-14 |
mouse |
Alessia Salamone, Gaetano Terrone, Rossella Di Sapia, Silvia Balosso, Teresa Ravizza, Luca Beltrame, Ilaria Craparotta, Laura Mannarino, Sara Raimondi Cominesi, Massimo Rizzi, Alberto Pauletti, Sergio Marchini, Luca Porcu, Till S Zimmer, Eleonora Aronica, Matthew During, Brett Abrahams, Shinichi Kondo, Toshiya Nishi, Annamaria Vezzan. Cholesterol 24-hydroxylase is a novel pharmacological target for anti-ictogenic and disease modification effects in epilepsy. Neurobiology of disease. 2022-08-06. PMID:35932989. |
high throughput rna-sequencing of hippocampal neurons and glia in mice treated with soticlestat during epileptogenesis showed that inhibition of cholesterol 24-hydroxylase did not directly affect the epileptogenic transcriptional network, but rather modulated a non-overlapping set of genes that might oppose the pathogenic mechanisms of the disease. |
2022-08-06 |
2023-08-14 |
mouse |
Ghazal Naseri Kouzehgarani, Mikhail E Kandel, Masayoshi Sakakura, Joshua S Dupaty, Gabriel Popescu, Martha U Gillett. Circadian Volume Changes in Hippocampal Glia Studied by Label-Free Interferometric Imaging. Cells. vol 11. issue 13. 2022-07-09. PMID:35805157. |
circadian volume changes in hippocampal glia studied by label-free interferometric imaging. |
2022-07-09 |
2023-08-14 |
Not clear |
Anabel R Simões, Marta Neto, Carolina S Alves, Mariana B Santos, Ismael Fernández-Hernández, Henrique Veiga-Fernandes, David Brea, Irene Durá, Juan M Encinas, Christa Rhine. Damage-responsive neuro-glial clusters coordinate the recruitment of dormant neural stem cells in Drosophila. Developmental cell. 2022-06-18. PMID:35716661. |
mammalian swim (lcn7) is also upregulated in glia of the mouse hippocampus upon brain injury. |
2022-06-18 |
2023-08-14 |
mouse |
Riaz Ahmad, Amjad Khan, Inayat Ur Rehman, Hyeon Jin Lee, Ibrahim Khan, Myeong Ok Ki. Lupeol Treatment Attenuates Activation of Glial Cells and Oxidative-Stress-Mediated Neuropathology in Mouse Model of Traumatic Brain Injury. International journal of molecular sciences. vol 23. issue 11. 2022-06-10. PMID:35682768. |
similarly, our results indicated that lupeol treatment inhibited glial cell activation, p-nf-κb, and downstream signaling molecules, such as tnf-α, cox-2, and il-1β, in the mouse cortex and hippocampus. |
2022-06-10 |
2023-08-14 |
mouse |
Viktor Aniol, Anna Manolova, Natalia Gulyaev. Early Life Events and Maturation of the Dentate Gyrus: Implications for Neurons and Glial Cells. International journal of molecular sciences. vol 23. issue 8. 2022-04-23. PMID:35457079. |
adverse events in early life provoke proinflammatory changes in hippocampal glia at cellular and molecular levels immediately after stress exposure. |
2022-04-23 |
2023-08-13 |
Not clear |
Dandan Yan, Lingling Dai, Xing Zhang, Yiqi Wang, Hong Ya. Subchronic Acrylamide Exposure Activates PERK-eIF2α Signaling Pathway and Induces Synaptic Impairment in Rat Hippocampus. ACS chemical neuroscience. 2022-04-20. PMID:35442627. |
acr exposure at 5 and 10 (mg/kg)/day by gavage for 14 weeks results in gait abnormality and cognitive impairment in rats, which were accompanied by neuronal loss, glial cell proliferation, and synaptic ultrastructure damage in the hippocampus. |
2022-04-20 |
2023-08-13 |
rat |
Yang Xu, Zejie Liu, Shuting Xu, Chengxian Li, Manrui Li, Shuqiang Cao, Yuwen Sun, Hao Dai, Yadong Guo, Xiameng Chen, Weibo Lian. Scientific Evidences of Calorie Restriction and Intermittent Fasting for Neuroprotection in Traumatic Brain Injury Animal Models: A Review of the Literature. Nutrients. vol 14. issue 7. 2022-04-12. PMID:35406044. |
this recovery is believed to be achieved by alleviating mitochondrial dysfunction, promoting hippocampal neurogenesis, inhibiting glial cell responses, shaping neural cell plasticity, as well as targeting apoptosis and autophagy. |
2022-04-12 |
2023-08-13 |
Not clear |
Mengtan Cai, Weihong Li. The Function of NF-Kappa B During Epilepsy, a Potential Therapeutic Target. Frontiers in neuroscience. vol 16. 2022-04-01. PMID:35360161. |
it is upregulated in neurons, glial cells, and endothelial cells, due to neuronal loss, glial cell proliferation, blood-brain barrier dysfunction, and hippocampal sclerosis through the glutamate and γ-aminobutyric acid imbalance, ion concentration changes, and other mechanisms. |
2022-04-01 |
2023-08-13 |
Not clear |
Junyoung Oh, Woo-Hyun Cho, Ellane Barcelon, Kwang Hwan Kim, Jinpyo Hong, Sung Joong Le. SARS-CoV-2 spike protein induces cognitive deficit and anxiety-like behavior in mouse via non-cell autonomous hippocampal neuronal death. Scientific reports. vol 12. issue 1. 2022-04-01. PMID:35361832. |
these neurological symptoms were accompanied by neuronal cell death in the dorsal and ventral hippocampus as well as glial cell activation. |
2022-04-01 |
2023-08-13 |
mouse |