| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bob Olsson, Radu Constantinescu, Björn Holmberg, Niels Andreasen, Kaj Blennow, Henrik Zetterber. The glial marker YKL-40 is decreased in synucleinopathies. Movement disorders : official journal of the Movement Disorder Society. vol 28. issue 13. 2014-06-27. PMID:23847144. |
microglia are resident immunosurveillant cells in the central nervous system, and astrocytes are important for blood flow, plasticity, and neurotransmitter regulation. |
2014-06-27 |
2023-08-12 |
Not clear |
| Dario Siniscalco, James Jeffrey Bradstreet, Nataliia Sych, Nicola Antonucc. Perspectives on the use of stem cells for autism treatment. Stem cells international. vol 2013. 2014-06-24. PMID:24222772. |
cells could be designed to target the observed molecular mechanisms of asds, that is, abnormal neurotransmitter regulation, activated microglia, mitochondrial dysfunction, blood-brain barrier disruptions, and chronic intestinal inflammation. |
2014-06-24 |
2023-08-12 |
Not clear |
| G Jean Harr. Microglia during development and aging. Pharmacology & therapeutics. vol 139. issue 3. 2014-03-05. PMID:23644076. |
changes in microglia phenotype relate to cellular processes including specific neurotransmitter, pattern recognition, or immune-related receptor activation. |
2014-03-05 |
2023-08-12 |
Not clear |
| Moonhee Le. Neurotransmitters and microglial-mediated neuroinflammation. Current protein & peptide science. vol 14. issue 1. 2013-09-13. PMID:23441898. |
the main purpose of this review is to summarize studies performed on neurotransmitter receptor expression in microglia, and the effects of their activation on microglial-mediated neuroinflammation. |
2013-09-13 |
2023-08-12 |
Not clear |
| Dorothy P Schafer, Emily K Lehrman, Beth Steven. The "quad-partite" synapse: microglia-synapse interactions in the developing and mature CNS. Glia. vol 61. issue 1. 2013-09-04. PMID:22829357. |
more recent imaging studies have revealed that microglia dynamically interact with synapses where they appear to serve as "synaptic sensors," responding to changes in neural activity and neurotransmitter release. |
2013-09-04 |
2023-08-12 |
mouse |
| María Domercq, Nuria Vázquez-Villoldo, Carlos Matut. Neurotransmitter signaling in the pathophysiology of microglia. Frontiers in cellular neuroscience. vol 7. 2013-04-30. PMID:23626522. |
neurotransmitter signaling in the pathophysiology of microglia. |
2013-04-30 |
2023-08-12 |
Not clear |
| Grietje Krabbe, Vitali Matyash, Ulrike Pannasch, Lauren Mamer, Hendrikus W G M Boddeke, Helmut Kettenman. Activation of serotonin receptors promotes microglial injury-induced motility but attenuates phagocytic activity. Brain, behavior, and immunity. vol 26. issue 3. 2012-06-22. PMID:22198120. |
microglia, the brain immune cell, express several neurotransmitter receptors which modulate microglial functions. |
2012-06-22 |
2023-08-12 |
mouse |
| Emma L Mead, Angelina Mosley, Simon Eaton, Lucianne Dobson, Simon J Heales, Jennifer M Pococ. Microglial neurotransmitter receptors trigger superoxide production in microglia; consequences for microglial-neuronal interactions. Journal of neurochemistry. vol 121. issue 2. 2012-05-21. PMID:22243365. |
microglial neurotransmitter receptors trigger superoxide production in microglia; consequences for microglial-neuronal interactions. |
2012-05-21 |
2023-08-12 |
rat |
| Emma L Mead, Angelina Mosley, Simon Eaton, Lucianne Dobson, Simon J Heales, Jennifer M Pococ. Microglial neurotransmitter receptors trigger superoxide production in microglia; consequences for microglial-neuronal interactions. Journal of neurochemistry. vol 121. issue 2. 2012-05-21. PMID:22243365. |
microglia also express neurotransmitter receptors, which can modulate microglial responses. |
2012-05-21 |
2023-08-12 |
rat |
| Emma L Mead, Angelina Mosley, Simon Eaton, Lucianne Dobson, Simon J Heales, Jennifer M Pococ. Microglial neurotransmitter receptors trigger superoxide production in microglia; consequences for microglial-neuronal interactions. Journal of neurochemistry. vol 121. issue 2. 2012-05-21. PMID:22243365. |
in this study, microglial activity of nox1, nox2 and nox4 in primary rat cultured microglia or the rodent bv2 cell line were altered by microglial neurotransmitter receptor modulation. |
2012-05-21 |
2023-08-12 |
rat |
| Emma L Mead, Angelina Mosley, Simon Eaton, Lucianne Dobson, Simon J Heales, Jennifer M Pococ. Microglial neurotransmitter receptors trigger superoxide production in microglia; consequences for microglial-neuronal interactions. Journal of neurochemistry. vol 121. issue 2. 2012-05-21. PMID:22243365. |
this has implications for the subsequent neurotoxic profile of microglia when neurotransmitter levels may become skewed in neurodegeneration. |
2012-05-21 |
2023-08-12 |
rat |
| S Petrosino, B Ménard, N Zsürger, V Di Marzo, J Chabr. Alteration of the endocannabinoid system in mouse brain during prion disease. Neuroscience. vol 177. 2012-01-19. PMID:21195746. |
microglial cell activation is a common feature of prion diseases; alterations of various neurotransmitter systems and neurotransmission have been also reported. |
2012-01-19 |
2023-08-12 |
mouse |
| Moonhee Lee, Edith G McGeer, Patrick L McGee. Mechanisms of GABA release from human astrocytes. Glia. vol 59. issue 11. 2012-01-06. PMID:21748804. |
gaba modulates the actions of microglia, indicating an important role for astrocytes beyond that of influencing neurotransmitter function. |
2012-01-06 |
2023-08-12 |
human |
| Stefanie Seifert, Maria Pannell, Wolfgang Uckert, Katrin Färber, Helmut Kettenman. Transmitter- and hormone-activated Ca(2+) responses in adult microglia/brain macrophages in situ recorded after viral transduction of a recombinant Ca(2+) sensor. Cell calcium. vol 49. issue 6. 2011-09-28. PMID:21536328. |
in vitro studies show that microglia, the resident immune cells of the brain, express neurotransmitter and neuropeptide receptors which are linked to ca(2+) signaling. |
2011-09-28 |
2023-08-12 |
mouse |
| Tiziana Bisogno, Vincenzo Di Marz. Cannabinoid receptors and endocannabinoids: role in neuroinflammatory and neurodegenerative disorders. CNS & neurological disorders drug targets. vol 9. issue 5. 2011-03-01. PMID:20632970. |
whilst cb₁ receptors are mostly expressed in neurons, where they regulate neurotransmitter release and synaptic strength, cb₂ receptors are found mostly in glial cells and microglia, which become activated and over-express these receptors during disorders such as alzheimer's disease, multiple sclerosis, amyotropic lateral sclerosis, parkinson's disease, and huntington's chorea. |
2011-03-01 |
2023-08-12 |
Not clear |
| Jianjun Zhai, Anna-Lena Ström, Renee Kilty, Priya Venkatakrishnan, James White, William V Everson, Eric J Smart, Haining Zh. Proteomic characterization of lipid raft proteins in amyotrophic lateral sclerosis mouse spinal cord. The FEBS journal. vol 276. issue 12. 2009-07-17. PMID:19438725. |
other protein changes were correlated with alterations in: microglia activation and inflammation; astrocyte and oligodendrocyte function; cell signaling; cellular stress response and apoptosis; and neuronal ion channels and neurotransmitter receptor functions. |
2009-07-17 |
2023-08-12 |
mouse |
| Miguel Díaz-Hernández, María Díez-Zaera, Jesús Sánchez-Nogueiro, Rosa Gómez-Villafuertes, Josep M Canals, Jordi Alberch, María Teresa Miras-Portugal, José J Luca. Altered P2X7-receptor level and function in mouse models of Huntington's disease and therapeutic efficacy of antagonist administration. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 23. issue 6. 2009-06-29. PMID:19171786. |
these are atp-gated cation channels known to modulate neurotransmitter release from neuronal presynaptic terminals and to regulate cytokine production and release from microglia. |
2009-06-29 |
2023-08-12 |
mouse |
| Vincent T Marti. New theories in the pathogenesis of menstrual migraine. Current pain and headache reports. vol 12. issue 6. 2009-05-22. PMID:18973740. |
it is postulated that estrogen withdrawal directly enhances excitability of trigeminal afferents, modulates the synthesis of neuropeptides, activates/deactivates specific neurotransmitter systems, and influences the function of microglia. |
2009-05-22 |
2023-08-12 |
Not clear |
| Dong Hyun Kim, Sunho Kim, Su Jin Jeon, Kun Ho Son, Seungjoo Lee, Byung Hoon Yoon, Jae Hoon Cheong, Kwang Ho Ko, Jong Hoon Ry. The effects of acute and repeated oroxylin A treatments on Abeta(25-35)-induced memory impairment in mice. Neuropharmacology. vol 55. issue 5. 2009-01-15. PMID:18620712. |
these results suggest that the amelioration of abeta(25-35) peptide-induced memory impairment by oroxylin a is mediated via the gabaergic neurotransmitter system after a single administration, or by reductions in abeta(25-35) peptide-induced astrocyte and microglia activations, inos expression, lipid peroxidation, and increased cholinergic neurotransmission after subchronic administration. |
2009-01-15 |
2023-08-12 |
mouse |
| Yan-Qiu Liu, Meng-Chun Cheng, Long-Xing Wang, Nan Zhao, Hong-Bin Xiao, Zheng-Tao Wan. Functional analysis of cultured neural cells for evaluating cold/cool- and hot/warm-natured Chinese herbs. The American journal of Chinese medicine. vol 36. issue 4. 2008-10-28. PMID:18711773. |
here, 20 chinese herbs, classified into 4 properties (hot, warm, cold and cool) of tcm, were analyzed for their ability to exhibit antioxidant action, to enhance glucose uptake by murine microglia n9 cells, and to influence neurotransmitter norepinephrine (ne) release from rat pheochromocytoma pc12 cells. |
2008-10-28 |
2023-08-12 |
rat |