| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mai Marie Holm, Jose Luis Nieto-Gonzalez, Irina Vardya, Kim Henningsen, Magdalena Niepsuj Jayatissa, Ove Wiborg, Kimmo Jense. Hippocampal GABAergic dysfunction in a rat chronic mild stress model of depression. Hippocampus. vol 21. issue 4. 2011-09-28. PMID:20087886. |
in summary, we have revealed a hippocampal dysfunction in the gabaergic system in the chronic mild stress model of depression in rats, caused by a reduction in action potential-dependent gaba release. |
2011-09-28 |
2023-08-12 |
rat |
| Nicola Kuczewski, Celine Fuchs, Nadine Ferrand, Jasmina N Jovanovic, Jean-Luc Gaiarsa, Christophe Porche. Mechanism of GABAB receptor-induced BDNF secretion and promotion of GABAA receptor membrane expression. Journal of neurochemistry. vol 118. issue 4. 2011-09-16. PMID:21255015. |
in a previous study, we reported that gaba(b) receptor activation triggers secretion of brain-derived neurotrophic factor (bdnf) and promotes the functional maturation of gabaergic synapses in the developing rat hippocampus. |
2011-09-16 |
2023-08-12 |
rat |
| O O Krupko, A S Tarasenko, N H Himmelreic. [Activation of presynaptic ionotropic glutamate receptors stimulates GABA release from hippocampal and cortical nerve terminals in rats]. Ukrains'kyi biokhimichnyi zhurnal (1999 ). vol 83. issue 2. 2011-09-16. PMID:21851046. |
we have revealed that specific agonists of kainate and nmda receptors, kainate and nmda, like glutamate, induced the release of [3h]gaba from hippocampal and cortical nerve terminals suggesting the involvement of both types in the regulation of gabaergic transmission. |
2011-09-16 |
2023-08-12 |
rat |
| Elodie Bruel-Jungerman, Paul J Lucassen, Fiona Franci. Cholinergic influences on cortical development and adult neurogenesis. Behavioural brain research. vol 221. issue 2. 2011-09-09. PMID:21272598. |
in the hippocampus such activity plays a role in the maturation of gabaergic synapses during the developmental shift from depolarizing to hyperpolarizing transmission. |
2011-09-09 |
2023-08-12 |
Not clear |
| Onder Albayram, Judith Alferink, Julika Pitsch, Anastasia Piyanova, Kim Neitzert, Karola Poppensieker, Daniela Mauer, Kerstin Michel, Anne Legler, Albert Becker, Krisztina Monory, Beat Lutz, Andreas Zimmer, Andras Bilkei-Gorz. Role of CB1 cannabinoid receptors on GABAergic neurons in brain aging. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 27. 2011-09-09. PMID:21690345. |
deletion of cb1 receptors from the forebrain gabaergic, but not from the glutamatergic neurons, led to a similar neuronal loss and increased neuroinflammation in the hippocampus as observed in animals lacking cb1 receptors in all cells. |
2011-09-09 |
2023-08-12 |
mouse |
| Onder Albayram, Judith Alferink, Julika Pitsch, Anastasia Piyanova, Kim Neitzert, Karola Poppensieker, Daniela Mauer, Kerstin Michel, Anne Legler, Albert Becker, Krisztina Monory, Beat Lutz, Andreas Zimmer, Andras Bilkei-Gorz. Role of CB1 cannabinoid receptors on GABAergic neurons in brain aging. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 27. 2011-09-09. PMID:21690345. |
our results suggest that cb1 receptor activity on hippocampal gabaergic neurons protects against age-dependent cognitive decline by reducing pyramidal cell degeneration and neuroinflammation. |
2011-09-09 |
2023-08-12 |
mouse |
| Endan Li, Dong Hyun Kim, Mudan Cai, Sungyoub Lee, Yumi Kim, Eunjin Lim, Jong Hoon Ryu, Terry G Unterman, Seungjoon Par. Hippocampus-dependent spatial learning and memory are impaired in growth hormone-deficient spontaneous dwarf rats. Endocrine journal. vol 58. issue 4. 2011-09-02. PMID:21350302. |
next, we examined the number of glutamatergic and gabaergic boutons in the hippocampal molecular layer and found a significant reduction in the density of vglut1+ boutons and an increase in gad6+ profiles, leading to a significantly reduced ratio in glutamatergic/gabaergic synapses. |
2011-09-02 |
2023-08-12 |
rat |
| Jochen Winterer, A Vanessa Stempel, Tamar Dugladze, Csaba Földy, Nino Maziashvili, Aleksandar R Zivkovic, Josef Priller, Ivan Soltesz, Tengis Gloveli, Dietmar Schmit. Cell-type-specific modulation of feedback inhibition by serotonin in the hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 23. 2011-09-01. PMID:21653851. |
our data imply an important role for serotonergic modulation of gabaergic action in subcortical control of hippocampal output. |
2011-09-01 |
2023-08-12 |
rat |
| Tzu-Ting Chiou, Bevan Bonhomme, Hongbing Jin, Celia P Miralles, Haiyan Xiao, Zhanyan Fu, Robert J Harvey, Kirsten Harvey, Stefano Vicini, Angel L De Bla. Differential regulation of the postsynaptic clustering of γ-aminobutyric acid type A (GABAA) receptors by collybistin isoforms. The Journal of biological chemistry. vol 286. issue 25. 2011-08-30. PMID:21540179. |
collybistin promotes submembrane clustering of gephyrin and is essential for the postsynaptic localization of gephyrin and γ-aminobutyric acid type a (gaba(a)) receptors at gabaergic synapses in hippocampus and amygdala. |
2011-08-30 |
2023-08-12 |
Not clear |
| Tzu-Ting Chiou, Bevan Bonhomme, Hongbing Jin, Celia P Miralles, Haiyan Xiao, Zhanyan Fu, Robert J Harvey, Kirsten Harvey, Stefano Vicini, Angel L De Bla. Differential regulation of the postsynaptic clustering of γ-aminobutyric acid type A (GABAA) receptors by collybistin isoforms. The Journal of biological chemistry. vol 286. issue 25. 2011-08-30. PMID:21540179. |
we have found that in transfected hippocampal neurons, all collybistin isoforms (cb2(sh3+), cb2(sh3-), cb3(sh3+), and cb3(sh3-)) target to and concentrate at gabaergic postsynapses. |
2011-08-30 |
2023-08-12 |
Not clear |
| A J McDonald, J F Muller, F Mascagn. Postsynaptic targets of GABAergic basal forebrain projections to the basolateral amygdala. Neuroscience. vol 183. 2011-08-26. PMID:21435381. |
recent studies indicate that the basolateral amygdala, like the neocortex and hippocampus, receives gabaergic inputs from the basal forebrain in addition to the well-established cholinergic inputs. |
2011-08-26 |
2023-08-12 |
rat |
| Michael Beaumont, Gianmaria Maccaferr. Is connexin36 critical for GABAergic hypersynchronization in the hippocampus? The Journal of physiology. vol 589. issue Pt 7. 2011-08-24. PMID:21300748. |
is connexin36 critical for gabaergic hypersynchronization in the hippocampus? |
2011-08-24 |
2023-08-12 |
mouse |
| Caren Armstrong, János Szabadics, Gábor Tamás, Ivan Soltes. Neurogliaform cells in the molecular layer of the dentate gyrus as feed-forward γ-aminobutyric acidergic modulators of entorhinal-hippocampal interplay. The Journal of comparative neurology. vol 519. issue 8. 2011-08-10. PMID:21452204. |
taken together, these results indicate that ngfcs form an integral part of the local molecular layer microcircuitry generating feed-forward inhibition and provide a direct gabaergic pathway linking the dentate gyrus to the ca1 and subicular regions through the hippocampal fissure. |
2011-08-10 |
2023-08-12 |
rat |
| Laxmikant S Deshpande, Robert E Blair, Robert J DeLorenz. Prolonged cannabinoid exposure alters GABA(A) receptor mediated synaptic function in cultured hippocampal neurons. Experimental neurology. vol 229. issue 2. 2011-08-05. PMID:21324315. |
approximately 60% of cb1 receptors colocalize to gabaergic terminals in hippocampal cultures. |
2011-08-05 |
2023-08-12 |
Not clear |
| Zeynep Kasap Varley, Rocco Pizzarelli, Roberta Antonelli, Stefka H Stancheva, Matthias Kneussel, Enrico Cherubini, Paola Zacch. Gephyrin regulates GABAergic and glutamatergic synaptic transmission in hippocampal cell cultures. The Journal of biological chemistry. vol 286. issue 23. 2011-08-05. PMID:21507951. |
gephyrin regulates gabaergic and glutamatergic synaptic transmission in hippocampal cell cultures. |
2011-08-05 |
2023-08-12 |
Not clear |
| Binbin Qian, Yajie Sun, Zhen Wu, Li Wan, Lulan Chen, Shuzhen Kong, Binhong Zhang, Fayong Zhang, Zhen-Yu Wang, Yun Wan. Epileptiform response of CA1 neurones to convulsant stimulation by cyclothiazide, kainic acid and pentylenetetrazol in anaesthetized rats. Seizure. vol 20. issue 4. 2011-08-03. PMID:21269843. |
in conclusion, ctz and ptz induced epileptiform activities are most likely to share a similar progressive pattern in hippocampus with gabaergic mechanism dominant in epileptogenesis, while ctz model involves additional glutamate receptor activation. |
2011-08-03 |
2023-08-12 |
rat |
| T Szilágyi, K Orbán-Kis, Emoke Horváth, Júlia Metz, Zsuzsanna Pap, Z Páva. Morphological identification of neuron types in the rat hippocampus. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. vol 52. issue 1. 2011-07-21. PMID:21424027. |
the strategic placement of inhibitory synapses, indicate that gabaergic interneurons belonging to different classes serve distinct functions in the hippocampal network. |
2011-07-21 |
2023-08-12 |
rat |
| B Luscher, Q Shen, N Sahi. The GABAergic deficit hypothesis of major depressive disorder. Molecular psychiatry. vol 16. issue 4. 2011-07-19. PMID:21079608. |
in particular, gabaergic transmission has an important role in the control of hippocampal neurogenesis and neural maturation, which are now established as cellular substrates of most if not all antidepressant therapies. |
2011-07-19 |
2023-08-12 |
mouse |
| Anton Ivanov, Monique Esclapez, Lotfi Ferha. Role of drebrin A in dendritic spine plasticity and synaptic function: Implications in neurological disorders. Communicative & integrative biology. vol 2. issue 3. 2011-07-14. PMID:19641748. |
indeed, our study showed that overexpression of drebrin a induced an increase of glutamatergic but not gabaergic synapses and resulted in the alteration of the normal excitatory-inhibitory ratio in favor of excitation in mature hippocampal neurons. |
2011-07-14 |
2023-08-12 |
Not clear |
| Shozo Jinn. Structural organization of long-range GABAergic projection system of the hippocampus. Frontiers in neuroanatomy. vol 3. 2011-07-14. PMID:19649167. |
structural organization of long-range gabaergic projection system of the hippocampus. |
2011-07-14 |
2023-08-12 |
Not clear |