| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Flavia Antonucci, Alán Alpár, Johannes Kacza, Matteo Caleo, Claudia Verderio, Alice Giani, Henrik Martens, Farrukh A Chaudhry, Manuela Allegra, Jens Grosche, Dominik Michalski, Christian Erck, Anke Hoffmann, Tibor Harkany, Michela Matteoli, Wolfgang Härti. Cracking down on inhibition: selective removal of GABAergic interneurons from hippocampal networks. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 6. 2012-03-27. PMID:22323713. |
inhibitory (gabaergic) interneurons entrain assemblies of excitatory principal neurons to orchestrate information processing in the hippocampus. |
2012-03-27 |
2023-08-12 |
mouse |
| Flavia Antonucci, Alán Alpár, Johannes Kacza, Matteo Caleo, Claudia Verderio, Alice Giani, Henrik Martens, Farrukh A Chaudhry, Manuela Allegra, Jens Grosche, Dominik Michalski, Christian Erck, Anke Hoffmann, Tibor Harkany, Michela Matteoli, Wolfgang Härti. Cracking down on inhibition: selective removal of GABAergic interneurons from hippocampal networks. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 6. 2012-03-27. PMID:22323713. |
here, we report the selective elimination of gabaergic interneurons by a ribosome inactivation approach through delivery of saporin-conjugated anti-vesicular gaba transporter antibodies (savas) in vitro as well as in the mouse and rat hippocampus in vivo. |
2012-03-27 |
2023-08-12 |
mouse |
| Flavia Antonucci, Alán Alpár, Johannes Kacza, Matteo Caleo, Claudia Verderio, Alice Giani, Henrik Martens, Farrukh A Chaudhry, Manuela Allegra, Jens Grosche, Dominik Michalski, Christian Erck, Anke Hoffmann, Tibor Harkany, Michela Matteoli, Wolfgang Härti. Cracking down on inhibition: selective removal of GABAergic interneurons from hippocampal networks. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 6. 2012-03-27. PMID:22323713. |
we demonstrate the selective loss of gabaergic--but not glutamatergic--synapses, reduced gaba release, and a shift in excitation/inhibition balance in mixed cultures of hippocampal neurons exposed to savas. |
2012-03-27 |
2023-08-12 |
mouse |
| Tyler K Best, Nathan P Cramer, Lina Chakrabarti, Tarik F Haydar, Zygmunt Galdzick. Dysfunctional hippocampal inhibition in the Ts65Dn mouse model of Down syndrome. Experimental neurology. vol 233. issue 2. 2012-03-26. PMID:22178330. |
gabaergic dysfunction is implicated in hippocampal deficits of the ts65dn mouse model of down syndrome (ds). |
2012-03-26 |
2023-08-12 |
mouse |
| Tyler K Best, Nathan P Cramer, Lina Chakrabarti, Tarik F Haydar, Zygmunt Galdzick. Dysfunctional hippocampal inhibition in the Ts65Dn mouse model of Down syndrome. Experimental neurology. vol 233. issue 2. 2012-03-26. PMID:22178330. |
since ts65dn mice overexpress g-protein coupled inward-rectifying potassium (girk2) containing channels, we sought to evaluate whether increased gabaergic function disrupts the functioning of hippocampal circuitry. |
2012-03-26 |
2023-08-12 |
mouse |
| Lucas Lecourtier, Anne Pereira de Vasconcelos, Elise Leroux, Brigitte Cosquer, Karin Geiger, Ségolène Lithfous, Jean-Christophe Casse. Septohippocampal pathways contribute to system consolidation of a spatial memory: sequential implication of GABAergic and cholinergic neurons. Hippocampus. vol 21. issue 12. 2012-03-25. PMID:20623740. |
although these pathways include, among others, cholinergic and gabaergic fibers innervating the hippocampus, research has essentially been oriented towards the role of their cholinergic component. |
2012-03-25 |
2023-08-12 |
rat |
| F Nazari-Serenjeh, A Rezayof, M-R Zarrindas. Functional correlation between GABAergic and dopaminergic systems of dorsal hippocampus and ventral tegmental area in passive avoidance learning in rats. Neuroscience. vol 196. 2012-02-23. PMID:21925239. |
functional correlation between gabaergic and dopaminergic systems of dorsal hippocampus and ventral tegmental area in passive avoidance learning in rats. |
2012-02-23 |
2023-08-12 |
rat |
| Po-Han Chiang, Pu-Yeh Wu, Tzu-Wei Kuo, Yu-Chao Liu, Chu-Fang Chan, Ta-Chun Chien, Jen-Kun Cheng, Yu-Yin Huang, Cheng-Di Chiu, Cheng-Chang Lie. GABA is depolarizing in hippocampal dentate granule cells of the adolescent and adult rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 1. 2012-02-22. PMID:22219270. |
whether such a transformation of gabaergic action occurs in dentate granule cells (dgcs), located at the first stage of the hippocampal trisynaptic circuit, is unclear. |
2012-02-22 |
2023-08-12 |
rat |
| Maryam Farahmandfar, Mohammad-Reza Zarrindast, Mehdi Kadivar, Seyed Morteza Karimian, Nasser Naghd. The effect of morphine sensitization on extracellular concentrations of GABA in dorsal hippocampus of male rats. European journal of pharmacology. vol 669. issue 1-3. 2012-02-08. PMID:21872582. |
although it has been shown that gabaergic systems in the ca1 region of dorsal hippocampus are involved in morphine sensitization, the alteration of extracellular level of gaba in this area in morphine sensitization has not been investigated. |
2012-02-08 |
2023-08-12 |
rat |
| Maryam Farahmandfar, Mohammad-Reza Zarrindast, Mehdi Kadivar, Seyed Morteza Karimian, Nasser Naghd. The effect of morphine sensitization on extracellular concentrations of GABA in dorsal hippocampus of male rats. European journal of pharmacology. vol 669. issue 1-3. 2012-02-08. PMID:21872582. |
these results suggest an adaptation of the gabaergic neuronal transmission in dorsal hippocampus induced by morphine sensitization and it is implied that opioid receptors may play an important role in this effect. |
2012-02-08 |
2023-08-12 |
rat |
| Charleen Salesse, Christopher Lacharité Mueller, Simon Chamberland, Lisa Topolni. Age-dependent remodelling of inhibitory synapses onto hippocampal CA1 oriens-lacunosum moleculare interneurons. The Journal of physiology. vol 589. issue Pt 20. 2012-02-07. PMID:21825029. |
here, we used whole-cell patch-clamp recordings in acute mouse hippocampal slices to study the properties and plasticity of gabaergic inhibitory synapses onto o-lm ins. |
2012-02-07 |
2023-08-12 |
mouse |
| Marlies Oostland, Jim Sellmeijer, Johannes A van Hoof. Transient expression of functional serotonin 5-HT3 receptors by glutamatergic granule cells in the early postnatal mouse cerebellum. The Journal of physiology. vol 589. issue Pt 20. 2012-02-07. PMID:21878518. |
the serotonin 5-ht(3) receptor is the only ligand-gated ion channel activated by serotonin and is expressed by gabaergic interneurons in many brain regions, including the cortex, amygdala and hippocampus. |
2012-02-07 |
2023-08-12 |
mouse |
| E M Stanley, J R Fade. Aging-related alterations in orexin/hypocretin modulation of septo-hippocampal amino acid neurotransmission. Neuroscience. vol 195. 2012-02-06. PMID:21884758. |
gabaergic neurons of the medial septum of the basal forebrain make up a substantial portion of the septo-hippocampal pathway fibers, and are known to modulate hippocampal amino acid neurotransmission and support cognitive function. |
2012-02-06 |
2023-08-12 |
rat |
| E M Stanley, J R Fade. Aging-related alterations in orexin/hypocretin modulation of septo-hippocampal amino acid neurotransmission. Neuroscience. vol 195. 2012-02-06. PMID:21884758. |
furthermore, immunohistochemical characterization of the medial septum revealed a significant decrease in parvalbumin (pv)-positive cell bodies in aged animals, and a significant reduction in orexin fiber innervation to the remaining gabaergic cells within the septum, while orexin innervation to the hippocampus was unaltered by the aging process. |
2012-02-06 |
2023-08-12 |
rat |
| Y-X Ge, Y Liu, H-Y Tang, X-G Liu, X Wan. ClC-2 contributes to tonic inhibition mediated by α5 subunit-containing GABA(A) receptor in experimental temporal lobe epilepsy. Neuroscience. vol 186. 2012-01-30. PMID:21549811. |
in adult hippocampus, the gabaergic cells mediate the major inhibitory function of the principal neurons, promoting the cl(-) entry through the gaba(a) receptor, whether through phasic (synaptic) or tonic (extrasynaptic) conductance. |
2012-01-30 |
2023-08-12 |
rat |
| Ghazal Banisadr, Bula J Bhattacharyya, Abdelhak Belmadani, Sarah C Izen, Dongjun Ren, Phuong B Tran, Richard J Mille. The chemokine BRAK/CXCL14 regulates synaptic transmission in the adult mouse dentate gyrus stem cell niche. Journal of neurochemistry. vol 119. issue 6. 2012-01-26. PMID:21955359. |
we observed that in the hippocampal dentate gyrus (dg) cxcl14 was expressed by gabaergic interneurons. |
2012-01-26 |
2023-08-12 |
mouse |
| Francine M Bene. Regulation of cell cycle and DNA repair in post-mitotic GABA neurons in psychotic disorders. Neuropharmacology. vol 60. issue 7-8. 2012-01-18. PMID:21184762. |
dysfunction of post-mitotic gabaergic neurons in the adult hippocampus of patients with psychotic disorders is associated with changes in the expression of genes that are involved in the maintenance of functional and genomic integrity of gaba cells. |
2012-01-18 |
2023-08-12 |
human |
| Wen Hu, Mingyue Zhang, Boldizsár Czéh, Weiqi Zhang, Gabriele Flügg. Chronic restraint stress impairs endocannabinoid mediated suppression of GABAergic signaling in the hippocampus of adult male rats. Brain research bulletin. vol 85. issue 6. 2012-01-11. PMID:21527320. |
chronic restraint stress impairs endocannabinoid mediated suppression of gabaergic signaling in the hippocampus of adult male rats. |
2012-01-11 |
2023-08-12 |
rat |
| Wen Hu, Mingyue Zhang, Boldizsár Czéh, Weiqi Zhang, Gabriele Flügg. Chronic restraint stress impairs endocannabinoid mediated suppression of GABAergic signaling in the hippocampus of adult male rats. Brain research bulletin. vol 85. issue 6. 2012-01-11. PMID:21527320. |
here we demonstrate that chronic restraint stress causes a dysfunction in cb1 mediated modulation of gabaergic transmission in the hippocampus. |
2012-01-11 |
2023-08-12 |
rat |
| Wen Hu, Mingyue Zhang, Boldizsár Czéh, Weiqi Zhang, Gabriele Flügg. Chronic restraint stress impairs endocannabinoid mediated suppression of GABAergic signaling in the hippocampus of adult male rats. Brain research bulletin. vol 85. issue 6. 2012-01-11. PMID:21527320. |
dsi is a form of short-term plasticity at gabaergic synapses that is known to be cb1 mediated and has been suggested to be involved in hippocampal information encoding. |
2012-01-11 |
2023-08-12 |
rat |