| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jing Liang, Yi Shen, Xuesi M Shao, Michael B Scott, Eddie Ly, Stephanie Wong, Albert Nguyen, Kevin Tan, Bill Kwon, Richard W Olsen, Igor Spigelma. Dihydromyricetin prevents fetal alcohol exposure-induced behavioral and physiological deficits: the roles of GABAA receptors in adolescence. Neurochemical research. vol 39. issue 6. 2015-01-26. PMID:24676702. |
patch-clamp recordings from dentate gyrus granule cells (dgcs) in hippocampal slices from fae (2.5 g/kg) rats at p25-35 revealed reduced sensitivity of gabaergic miniature inhibitory postsynaptic currents (mipscs) and tonic current (itonic) to potentiation by zolpidem (0.3 μm). |
2015-01-26 |
2023-08-12 |
rat |
| Jing Liang, Héctor E López-Valdés, Hilda Martínez-Coria, A Kerstin Lindemeyer, Yi Shen, Xuesi M Shao, Richard W Olse. Dihydromyricetin ameliorates behavioral deficits and reverses neuropathology of transgenic mouse models of Alzheimer's disease. Neurochemical research. vol 39. issue 6. 2015-01-26. PMID:24728903. |
we found that gephyrin, a postsynaptic gabaar anchor protein that regulates the formation and plasticity of gabaergic synapses, decreased in hippocampus and cortex in tg-swdi. |
2015-01-26 |
2023-08-13 |
mouse |
| J C González, G Lignani, M Maroto, P Baldelli, J M Hernández-Guij. Presynaptic muscarinic receptors reduce synaptic depression and facilitate its recovery at hippocampal GABAergic synapses. Cerebral cortex (New York, N.Y. : 1991). vol 24. issue 7. 2015-01-23. PMID:23425889. |
presynaptic muscarinic receptors reduce synaptic depression and facilitate its recovery at hippocampal gabaergic synapses. |
2015-01-23 |
2023-08-12 |
Not clear |
| J C González, G Lignani, M Maroto, P Baldelli, J M Hernández-Guij. Presynaptic muscarinic receptors reduce synaptic depression and facilitate its recovery at hippocampal GABAergic synapses. Cerebral cortex (New York, N.Y. : 1991). vol 24. issue 7. 2015-01-23. PMID:23425889. |
hippocampal gamma oscillation, involved in cognitive processes, can be induced by muscarinic acetylcholine receptors activation and depends in large part on the activation of γ-aminobutyric acidergic (gabaergic) interneurons. |
2015-01-23 |
2023-08-12 |
Not clear |
| J C González, G Lignani, M Maroto, P Baldelli, J M Hernández-Guij. Presynaptic muscarinic receptors reduce synaptic depression and facilitate its recovery at hippocampal GABAergic synapses. Cerebral cortex (New York, N.Y. : 1991). vol 24. issue 7. 2015-01-23. PMID:23425889. |
these results show that muscarinic modulation of hippocampal gabaergic synapses confers a greater resistance to sustain periods of intense synaptic activity in the gamma frequency range. |
2015-01-23 |
2023-08-12 |
Not clear |
| Baiping Wang, Zilai Wang, Lu Sun, Li Yang, Hongmei Li, Allysa L Cole, Jennifer Rodriguez-Rivera, Hui-Chen Lu, Hui Zhen. The amyloid precursor protein controls adult hippocampal neurogenesis through GABAergic interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 40. 2015-01-20. PMID:25274811. |
the amyloid precursor protein controls adult hippocampal neurogenesis through gabaergic interneurons. |
2015-01-20 |
2023-08-13 |
mouse |
| Baiping Wang, Zilai Wang, Lu Sun, Li Yang, Hongmei Li, Allysa L Cole, Jennifer Rodriguez-Rivera, Hui-Chen Lu, Hui Zhen. The amyloid precursor protein controls adult hippocampal neurogenesis through GABAergic interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 40. 2015-01-20. PMID:25274811. |
app controls adult neurogenesis through a non cell-autonomous mechanism by gabaergic neurons, as selective deletion of gabaergic, but not glutamatergic, app disrupts adult hippocampal neurogenesis. |
2015-01-20 |
2023-08-13 |
mouse |
| Baiping Wang, Zilai Wang, Lu Sun, Li Yang, Hongmei Li, Allysa L Cole, Jennifer Rodriguez-Rivera, Hui-Chen Lu, Hui Zhen. The amyloid precursor protein controls adult hippocampal neurogenesis through GABAergic interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 40. 2015-01-20. PMID:25274811. |
our studies uncover an indispensable role of app in the gabaergic system for controlling adult hippocampal neurogenesis, and our findings indicate that app dysfunction may contribute to impaired neurogenesis and cognitive decline associated with ad. |
2015-01-20 |
2023-08-13 |
mouse |
| Katharine W Henderson, Jyoti Gupta, Stephanie Tagliatela, Elizabeth Litvina, XiaoTing Zheng, Meghan A Van Zandt, Nicholas Woods, Ethan Grund, Diana Lin, Sara Royston, Yuchio Yanagawa, Gloster B Aaron, Janice R Naegel. Long-term seizure suppression and optogenetic analyses of synaptic connectivity in epileptic mice with hippocampal grafts of GABAergic interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 40. 2015-01-20. PMID:25274826. |
long-term seizure suppression and optogenetic analyses of synaptic connectivity in epileptic mice with hippocampal grafts of gabaergic interneurons. |
2015-01-20 |
2023-08-13 |
mouse |
| Jonathan C Bean, Thiri W Lin, Anupama Sathyamurthy, Fang Liu, Dong-Min Yin, Wen-Cheng Xiong, Lin Me. Genetic labeling reveals novel cellular targets of schizophrenia susceptibility gene: distribution of GABA and non-GABA ErbB4-positive cells in adult mouse brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 40. 2015-01-20. PMID:25274830. |
almost all erbb4-positive cells were gabaergic in cortex, hippocampus, basal ganglia, and most of amygdala in neonatal and adult mice, suggesting gabaergic transmission as a major target of nrg1-erbb4 signaling in these regions. |
2015-01-20 |
2023-08-13 |
mouse |
| Robin Nguyen, Mark D Morrissey, Vivek Mahadevan, Janine D Cajanding, Melanie A Woodin, John S Yeomans, Kaori Takehara-Nishiuchi, Jun Chul Ki. Parvalbumin and GAD65 interneuron inhibition in the ventral hippocampus induces distinct behavioral deficits relevant to schizophrenia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 45. 2015-01-20. PMID:25378161. |
together, these findings establish a causal role for vhpc gaba neurons in controlling behaviors relevant to schizophrenia and suggest a functional dissociation between the gabaergic mechanisms involved in hippocampal modulation of sensorimotor processes. |
2015-01-20 |
2023-08-13 |
mouse |
| Heidi O Nousiainen, Ileana B Quintero, Timo T Myöhänen, Vootele Voikar, Jelena Mijatovic, Mikael Segerstråle, Annakaisa M Herrala, Natalia Kulesskaya, Anitta E Pulkka, Tanja Kivinummi, Usama Abo-Ramadan, Tomi Taira, T Petteri Piepponen, Heikki Rauvala, Pirkko Vihk. Mice deficient in transmembrane prostatic acid phosphatase display increased GABAergic transmission and neurological alterations. PloS one. vol 9. issue 5. 2015-01-15. PMID:24846136. |
in addition to increased anxiety, disturbed prepulse inhibition, increased synthesis of striatal dopamine, and augmented response to amphetamine, pap-deficient mice have enlarged lateral ventricles, reduced diazepam-induced loss of righting reflex, and increased gabaergic tone in the hippocampus. |
2015-01-15 |
2023-08-13 |
mouse |
| YeeWen Candace Wu, Xin Du, Maarten van den Buuse, Rachel A Hil. Sex differences in the adolescent developmental trajectory of parvalbumin interneurons in the hippocampus: a role for estradiol. Psychoneuroendocrinology. vol 45. 2015-01-12. PMID:24845187. |
reduced hippocampal expression of the gabaergic interneuron marker, parvalbumin (pv), and gaba synthesizing enzyme, gad67, are consistently reported in schizophrenia. |
2015-01-12 |
2023-08-13 |
mouse |
| Diana I Rodrigues, Jessié Gutierres, Anna Pliássova, Catarina R Oliveira, Rodrigo A Cunha, Paula Agostinh. Synaptic and sub-synaptic localization of amyloid-β protein precursor in the rat hippocampus. Journal of Alzheimer's disease : JAD. vol 40. issue 4. 2015-01-06. PMID:24531160. |
these results provide the first direct demonstration that aβpp is mostly distributed among glutamatergic rather than gabaergic or cholinergic terminals of the adult rat hippocampus, in remarkable agreement with the particular susceptibility to dysfunction and degeneration of glutamatergic synapses in early ad. |
2015-01-06 |
2023-08-12 |
rat |
| Azadeh A Rikani, Zia Choudhry, Adnan M Choudhry, Georgios Zenonos, Sadaf Tariq, Nusrat J Mobassara. Spatially regulated adult neurogenesis. Annals of neurosciences. vol 20. issue 2. 2014-12-31. PMID:25206016. |
regardless of the unique functional roles of ongoing neurogenesis in olfactory bulb and hippocampus, the differences are in terms of consequence of neurogenesis, origin of newly born neurons, responding receptors to nicotine exposure, neuronal migration and gabaergic input between two regions. |
2014-12-31 |
2023-08-13 |
Not clear |
| Hongbing Jin, Tzu-Ting Chiou, David R Serwanski, Celia P Miralles, Noelia Pinal, Angel L De Bla. Ring finger protein 34 (RNF34) interacts with and promotes γ-aminobutyric acid type-A receptor degradation via ubiquitination of the γ2 subunit. The Journal of biological chemistry. vol 289. issue 42. 2014-12-22. PMID:25193658. |
immunofluorescence of cultured hippocampal neurons shows that rnf34 forms clusters and that a subset of these clusters is associated with gabaergic synapses. |
2014-12-22 |
2023-08-13 |
rat |
| Hongbing Jin, Tzu-Ting Chiou, David R Serwanski, Celia P Miralles, Noelia Pinal, Angel L De Bla. Ring finger protein 34 (RNF34) interacts with and promotes γ-aminobutyric acid type-A receptor degradation via ubiquitination of the γ2 subunit. The Journal of biological chemistry. vol 289. issue 42. 2014-12-22. PMID:25193658. |
overexpression of rnf34 in hippocampal neurons decreases the density of γ2 gabaar clusters and the number of gabaergic contacts that these neurons receive. |
2014-12-22 |
2023-08-13 |
rat |
| Jonas Waider, Florian Proft, Georg Langlhofer, Esther Asan, Klaus-Peter Lesch, Lise Gutknech. GABA concentration and GABAergic neuron populations in limbic areas are differentially altered by brain serotonin deficiency in Tph2 knockout mice. Histochemistry and cell biology. vol 139. issue 2. 2014-12-17. PMID:23052836. |
in addition, unbiased stereological estimation of gabaergic interneuron numbers and density was performed in subregions of amygdala and hippocampus. |
2014-12-17 |
2023-08-12 |
mouse |
| Jing Ding, Jing-Jing Wang, Chen Huang, Li Wang, Shining Deng, Tian-Le Xu, Wei-Hong Ge, Wei-Guang Li, Fei L. Curcumol from Rhizoma Curcumae suppresses epileptic seizure by facilitation of GABA(A) receptors. Neuropharmacology. vol 81. 2014-12-15. PMID:24565642. |
measurement of tonic and miniature inhibitory postsynaptic gabaergic currents in hippocampal slices indicated that curcumol enhanced both forms of inhibition. |
2014-12-15 |
2023-08-12 |
mouse |
| Y Hatayama, T Hashimoto, H Kohayakawa, T Kiyoshi, K Nakamichi, T Kinoshita, N Yoshid. In vivo pharmacological characterization of AC-3933, a benzodiazepine receptor partial inverse agonist for the treatment of Alzheimer's disease. Neuroscience. vol 265. 2014-12-09. PMID:24513386. |
we have previously reported that 5-(3-methoxyphenyl)-3-(5-methyl-1,2,4-oxadiazol-3-yl)-1,6-naphthyridin-2(1h)-one (ac-3933), a partial inverse agonist for the benzodiazepine receptor (bzr), reverses gabaergic inhibitory effect on cholinergic neurons, and thus enhances acetylcholine release from these neurons in rat hippocampal slices. |
2014-12-09 |
2023-08-12 |
rat |