| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| YuYing Huang, JunFang Chen, Ying Chen, YingHan Zhuang, Mu Sun, Thomas Behnisc. The neurotoxin 1-methyl-4-phenylpyridinium (MPP(+)) alters hippocampal excitatory synaptic transmission by modulation of the GABAergic system. Frontiers in cellular neuroscience. vol 9. 2015-08-24. PMID:26300734. |
taking these data together, we suggest that mpp(+) affects hippocampal synaptic transmission by enhancing some aspects of the hippocampal gabaergic system. |
2015-08-24 |
2023-08-13 |
mouse |
| Javier Del Pino, María Teresa Frejo, María José Anadon Baselga, Miguel Andrés Capo, Paula Moyano, José Manuel García, María Jesús Día. Neuroprotective or neurotoxic effects of 4-aminopyridine mediated by KChIP1 regulation through adjustment of Kv 4.3 potassium channels expression and GABA-mediated transmission in primary hippocampal cells. Toxicology. vol 333. 2015-08-17. PMID:25917026. |
we evaluated, in wild type and kchip1 silenced primary hippocampal neurons, the effect of 4-ap (0.25μm to 2mm) with or without semicarbazide (0.3m) co-treatment after 24h and after 14 days 4-ap alone exposure on cell viability, the effect of 4-ap (0.25μm to 2mm) on kchip1 and kv 4.3 potassium channels gene expression and gabaergic transmission after 24h treatment or after 14 days exposure to 4-ap (0.25μm to1μm). |
2015-08-17 |
2023-08-13 |
Not clear |
| Robert Lübkemann, Judith Eberhardt, Friedrich-Wilhelm Röhl, Kathrin Janitzky, Sven Nullmeier, Oliver Stork, Herbert Schwegler, Rüdiger Link. Identification and Characterization of GABAergic Projection Neurons from Ventral Hippocampus to Amygdala. Brain sciences. vol 5. issue 3. 2015-08-12. PMID:26264032. |
identification and characterization of gabaergic projection neurons from ventral hippocampus to amygdala. |
2015-08-12 |
2023-08-13 |
Not clear |
| Robert Lübkemann, Judith Eberhardt, Friedrich-Wilhelm Röhl, Kathrin Janitzky, Sven Nullmeier, Oliver Stork, Herbert Schwegler, Rüdiger Link. Identification and Characterization of GABAergic Projection Neurons from Ventral Hippocampus to Amygdala. Brain sciences. vol 5. issue 3. 2015-08-12. PMID:26264032. |
gabaergic local circuit neurons are critical for the network activity and functional interaction of the amygdala and hippocampus. |
2015-08-12 |
2023-08-13 |
Not clear |
| Robert Lübkemann, Judith Eberhardt, Friedrich-Wilhelm Röhl, Kathrin Janitzky, Sven Nullmeier, Oliver Stork, Herbert Schwegler, Rüdiger Link. Identification and Characterization of GABAergic Projection Neurons from Ventral Hippocampus to Amygdala. Brain sciences. vol 5. issue 3. 2015-08-12. PMID:26264032. |
previously, we obtained evidence for a gabaergic contribution to the hippocampal projection into the basolateral amygdala. |
2015-08-12 |
2023-08-13 |
Not clear |
| Robert Lübkemann, Judith Eberhardt, Friedrich-Wilhelm Röhl, Kathrin Janitzky, Sven Nullmeier, Oliver Stork, Herbert Schwegler, Rüdiger Link. Identification and Characterization of GABAergic Projection Neurons from Ventral Hippocampus to Amygdala. Brain sciences. vol 5. issue 3. 2015-08-12. PMID:26264032. |
using fluorogold retrograde labeling, we now demonstrate that this projection indeed has a prominent gabaergic component comprising 17% of the gabaergic neurons in the ventral hippocampus. |
2015-08-12 |
2023-08-13 |
Not clear |
| Rebecca Ravenelle, Nichole M Neugebauer, Timothy Niedzielak, S Tiffany Donaldso. Sex differences in diazepam effects and parvalbumin-positive GABA neurons in trait anxiety Long Evans rats. Behavioural brain research. vol 270. 2015-08-06. PMID:24815212. |
immunohistochemical analysis for parvalbumin (pv; a calcium-binding protein that selectively stains gabaergic neurons) in central amygdala (cea), caudate putamen (cpu) and the hippocampus indicated the number of gabaergic interneurons in these areas differed across sex and anxiety trait. |
2015-08-06 |
2023-08-13 |
rat |
| Xiaochen Wang, Fei Gao, Jianchun Zhu, Enpu Guo, Xueying Song, Shuanglian Wang, Ren-Zhi Zha. Immunofluorescently labeling glutamic acid decarboxylase 65 coupled with confocal imaging for identifying GABAergic somata in the rat dentate gyrus-A comparison with labeling glutamic acid decarboxylase 67. Journal of chemical neuroanatomy. vol 61-62. 2015-07-31. PMID:25058170. |
however, identifying gabaergic cell bodies with gad67 immunoreactivity in the hippocampal dentate gyrus, especially in the hilus, is not without pitfalls. |
2015-07-31 |
2023-08-13 |
mouse |
| Dong Wei, Fang Yang, Ying Wang, Feng Yang, Chen Wu, Sheng-Xi Wu, Wen Jian. Degeneration and regeneration of GABAergic interneurons in the dentate gyrus of adult mice in experimental models of epilepsy. CNS neuroscience & therapeutics. vol 21. issue 1. 2015-07-28. PMID:25272022. |
mounting evidence showed that gabaergic interneurons play an important role in the generation of seizures by regulating excitatory/inhibitory balance in the hippocampus; however, there is a continuous debate regarding the alteration in the number of hippocampal gabaergic interneurons during epileptogenesis. |
2015-07-28 |
2023-08-13 |
mouse |
| Roberta Antonelli, Rocco Pizzarelli, Andrea Pedroni, Jean-Marc Fritschy, Giannino Del Sal, Enrico Cherubini, Paola Zacch. Pin1-dependent signalling negatively affects GABAergic transmission by modulating neuroligin2/gephyrin interaction. Nature communications. vol 5. 2015-07-15. PMID:25297980. |
as a consequence, enhanced accumulation of nl2, gephyrin and gabaa receptors was detected at gabaergic synapses in the hippocampus of pin1-knockout mice (pin1-/-) associated with an increase in amplitude of spontaneous gabaa-mediated post-synaptic currents. |
2015-07-15 |
2023-08-13 |
mouse |
| Meng Chang Ko, Min Chong Lee, Tamara G Amstislavskaya, Maria A Tikhonova, Yi-Ling Yang, Kwok-Tung L. Inhibition of NKCC1 attenuated hippocampal LTP formation and inhibitory avoidance in rat. PloS one. vol 9. issue 11. 2015-07-01. PMID:25369049. |
given that loop diuretics may act as antiepileptic drugs that modulate gabaergic signaling, we sought to investigate whether they also affect hippocampal function. |
2015-07-01 |
2023-08-13 |
rat |
| Holger Haselmann, Luise Röpke, Christian Werner, Albrecht Kunze, Christian Gei. Interactions of Human Autoantibodies with Hippocampal GABAergic Synaptic Transmission - Analyzing Antibody-Induced Effects ex vivo. Frontiers in neurology. vol 6. 2015-06-30. PMID:26124746. |
interactions of human autoantibodies with hippocampal gabaergic synaptic transmission - analyzing antibody-induced effects ex vivo. |
2015-06-30 |
2023-08-13 |
mouse |
| Krzysztof Tokarski, Magdalena Kusek, Joanna Sowa, Bartosz Bobul. [Possible involvement of 5-HT₇ receptor in pathophysiology of affective disorders and action of antidepressant drugs]. Postepy higieny i medycyny doswiadczalnej (Online). vol 68. 2015-06-26. PMID:25228519. |
at the cellular level, 5-ht7 receptors increase the excitability of excitatory cells and appear to modulate both glutamatergic and gabaergic transmission in the hippocampus. |
2015-06-26 |
2023-08-13 |
rat |
| Yoshiyasu Kigawa, Eri Hashimoto, Wataru Ukai, Takao Ishii, Kengo Furuse, Hanako Tsujino, Tomohiro Shirasaka, Toshikazu Sait. Stem cell therapy: a new approach to the treatment of refractory depression. Journal of neural transmission (Vienna, Austria : 1996). vol 121. issue 10. 2015-06-16. PMID:24671607. |
the combined exposures of prenatal and adolescent stress resulted in a reduction in parvalbumin (pv)-positive phenotype of gabaergic interneurons and reduced postsynaptic density protein 95 (psd-95) levels in the anterior cingulate cortex, amygdala, and hippocampus. |
2015-06-16 |
2023-08-12 |
rat |
| L Huang, L B Zhao, Z Y Yu, X J He, L P Ma, N Li, L J Guo, W Y Fen. Long-term inhibition of Rho-kinase restores the LTP impaired in chronic forebrain ischemia rats by regulating GABAA and GABAB receptors. Neuroscience. vol 277. 2015-06-08. PMID:25050822. |
in summary, our results indicated that the inactivation of rho-kinase could enhance gabaa and gabab expressions by different mechanisms to guarantee the induction of hippocampal ltp, and it could decrease the phosphorylation level of gabaergic inhibitory interneurons to promote the ltp induction rate and magnitude, hence improving the cognitive deficit suffered after chronic forebrain ischemia. |
2015-06-08 |
2023-08-13 |
rat |
| H Moradi-Chameh, J Peng, C Wu, L Zhan. Intracellular activities related to in vitro hippocampal sharp waves are altered in CA3 pyramidal neurons of aged mice. Neuroscience. vol 277. 2015-06-08. PMID:25088916. |
in view of accumulating evidence indicating a decrease in subgroups of hippocampal gabaergic interneurons in aged animals, we test the hypothesis that the intracellular activities related to in vitro spws are altered in ca3 pyramidal neurons of aged mice. |
2015-06-08 |
2023-08-13 |
mouse |
| Vera Tsintsadze, Marat Minlebaev, Dimitry Suchkov, Mark O Cunningham, Roustem Khazipo. Ontogeny of kainate-induced gamma oscillations in the rat CA3 hippocampus in vitro. Frontiers in cellular neuroscience. vol 9. 2015-06-04. PMID:26041996. |
gabaergic inhibition, which is instrumental in the generation of hippocampal gamma oscillations, undergoes significant changes during development. |
2015-06-04 |
2023-08-13 |
rat |
| Vera Tsintsadze, Marat Minlebaev, Dimitry Suchkov, Mark O Cunningham, Roustem Khazipo. Ontogeny of kainate-induced gamma oscillations in the rat CA3 hippocampus in vitro. Frontiers in cellular neuroscience. vol 9. 2015-06-04. PMID:26041996. |
bumetanide, a nkcc1 chloride co-transporter antagonist which renders gabaergic responses inhibitory in the immature hippocampal neurons, failed to induce ka-os at p2-4 indicating that the absence of ka-os in neonates is not due to depolarizing actions of gaba. |
2015-06-04 |
2023-08-13 |
rat |
| Vera Tsintsadze, Marat Minlebaev, Dimitry Suchkov, Mark O Cunningham, Roustem Khazipo. Ontogeny of kainate-induced gamma oscillations in the rat CA3 hippocampus in vitro. Frontiers in cellular neuroscience. vol 9. 2015-06-04. PMID:26041996. |
the linear developmental profile, electrographic features and pharmacological properties indicate that ca3 hippocampal beta and gamma ka-os are fundamentally similar in their generative mechanisms and their delayed onset and developmental changes likely reflect the development of perisomatic gabaergic inhibition. |
2015-06-04 |
2023-08-13 |
rat |
| b' Susana Garc\\xc3\\xada-Cerro, Paula Mart\\xc3\\xadnez, Ver\\xc3\\xb3nica Vidal, Andrea Corrales, Jes\\xc3\\xbas Fl\\xc3\\xb3rez, Rebeca Vidal, Noem\\xc3\\xad Rueda, Mar\\xc3\\xada L Arbon\\xc3\\xa9s, Carmen Mart\\xc3\\xadnez-Cu\\xc3\\xa. Overexpression of Dyrk1A is implicated in several cognitive, electrophysiological and neuromorphological alterations found in a mouse model of Down syndrome. PloS one. vol 9. issue 9. 2015-05-15. PMID:25188425.' |
concomitant with these functional improvements, normalization of the dyrk1a expression level in ts mice restored the proliferation and differentiation of hippocampal cells in the adult dentate gyrus (dg) and the density of gabaergic and glutamatergic synapse markers in the molecular layer of the hippocampus. |
2015-05-15 |
2023-08-13 |
mouse |