| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Saligaut, M Daoust, M Chadelaud, N Moore, P Chretien, F Boismar. Oxotremorine-induced cholinergic syndrome: modifications by levodopa and/or oral cytidine diphosphocholine. Methods and findings in experimental and clinical pharmacology. vol 7. issue 1. 1985-06-07. PMID:3990445. |
the proven efficacy of cdp-choline in parkinsonism could then be mediated by a hypersensitivity of some cerebral dopamine receptors, and not by a direct stimulating effect of the striatal dopaminergic receptors. |
1985-06-07 |
2023-08-11 |
mouse |
| M L Dubocovich, N R Zahnise. Binding characteristics of the dopamine uptake inhibitor [3H]nomifensine to striatal membranes. Biochemical pharmacology. vol 34. issue 8. 1985-06-06. PMID:3158318. |
these results suggest that [3h]nomifensine binds to a site on dopaminergic nerve terminals associated with the dopamine uptake pump. |
1985-06-06 |
2023-08-11 |
rat |
| D Barone, A Assandri, G Galliani, A Glässer, G Tarzi. Characterization of [3H]zetidoline binding to rat striatal membranes. The Journal of pharmacy and pharmacology. vol 37. issue 3. 1985-05-23. PMID:2858565. |
inhibition studies indicated that only dopamine and dopaminergic agents are able to displace [3h]zetidoline from its binding sites, and in a different rank order from that for displacement of [3h]spiperone. |
1985-05-23 |
2023-08-11 |
rat |
| O Serri, G Renier, M Somm. Effects of alloxan-induced diabetes on dopaminergic receptors in rat striatum and anterior pituitary. Hormone research. vol 21. issue 2. 1985-05-23. PMID:3979949. |
the interaction of metoclopramide with striatal dopaminergic receptors was slightly modified, while that of dopamine, bromocriptine and haloperidol was unaffected. |
1985-05-23 |
2023-08-11 |
rat |
| A Albanese, M C Altavist. Neuropeptides in dopamine-containing regions of the brain. Italian journal of neurological sciences. vol 5. issue 4. 1985-05-20. PMID:6152262. |
neuropeptides coexist with dopamine in specific dopamine-containing neurons; in addition they interact abundantly with the dopaminergic neurons, by acting either on the perikarya or on the dopaminergic nerve terminals. |
1985-05-20 |
2023-08-12 |
Not clear |
| A Janowsky, M M Schweri, P Berger, R Long, P Skolnick, S M Pau. The effects of surgical and chemical lesions on striatal [3H]threo-(+/-)-methylphenidate binding: correlation with [3H]dopamine uptake. European journal of pharmacology. vol 108. issue 2. 1985-05-15. PMID:3920060. |
these data suggest that the specific binding sites for [3h]-threo-(+/-)-methylphenidate in striatum are localized to dopaminergic nerve terminals, and may be associated with the dopamine transport complex. |
1985-05-15 |
2023-08-11 |
rat |
| A Dumbrille-Ross, P Seema. Dopamine receptor elevation by cholecystokinin. Peptides. vol 5. issue 6. 1985-05-15. PMID:6531273. |
these results suggest that cck elevates dopamine d2 receptors in the accumbens and striatum and may be a physiological modulator of the dopaminergic system. |
1985-05-15 |
2023-08-12 |
rat |
| K Y Ho, G A Smythe, L Lazaru. Enhanced hypothalamic dopaminergic inhibition of LH, TSH and GH release in patients with pathological hyperprolactinaemia. Acta endocrinologica. vol 108. issue 3. 1985-05-13. PMID:3984660. |
recent studies have suggested that patients with prolactinomas have a defect in the central regulation of prolactin (prl) release but it is not clear whether the defect results from a true loss of hypothalamic dopamine activity or from a functional inability of inherent dopaminergic inhibition to be mediated effectively. |
1985-05-13 |
2023-08-11 |
human |
| K Y Ho, G A Smythe, L Lazaru. Enhanced hypothalamic dopaminergic inhibition of LH, TSH and GH release in patients with pathological hyperprolactinaemia. Acta endocrinologica. vol 108. issue 3. 1985-05-13. PMID:3984660. |
we have studied this question by the use of monoiodtyrosine (mit, 1 g orally), a specific inhibitor of central dopamine synthesis to remove dopaminergic inhibitory control of prl release in 10 normal ovulating women, 8 women on oral contraceptive steroids (oc) and 8 patients with pathological hyperprolactinaemia (php). |
1985-05-13 |
2023-08-11 |
human |
| F Hefti, A Enz, E Melame. Partial lesions of the nigrostriatal pathway in the rat. Acceleration of transmitter synthesis and release of surviving dopaminergic neurones by drugs. Neuropharmacology. vol 24. issue 1. 1985-05-10. PMID:2858830. |
in rats with partial, unilateral lesions of the dopaminergic nigrostriatal pathway, synthesis of dopamine (da) per surviving neurone was assessed by measuring the ratio of dopa accumulated after inhibition of aromatic amino acid decarboxylase to dopamine (dopa/da ratio). |
1985-05-10 |
2023-08-11 |
rat |
| G E Martin, D J Pettibon. Dopamine agonist activity of EMD 23,448. Journal of neural transmission. vol 61. issue 1-2. 1985-05-03. PMID:4038993. |
emd 23,448 was examined in tests of dopaminergic function and was found to be an atypical dopamine (da) agonist. |
1985-05-03 |
2023-08-11 |
mouse |
| G J Lees, R R Kydd, J J Wrigh. Relationship between sensorimotor neglect and the specificity, degree and locus of mesotelencephalic dopaminergic cell loss following 6-hydroxydopamine. Psychopharmacology. vol 85. issue 1. 1985-04-26. PMID:3920693. |
firstly, dopaminergic specificity of the neglect was further established by studying the relationship between nomifensine protection of dopamine cells against 6-hydroxydopamine damage and the degree of neglect which resulted. |
1985-04-26 |
2023-08-11 |
Not clear |
| R Markstein, D Lahay. Neurochemical investigations in vitro with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in preparations of rat brain. European journal of pharmacology. vol 106. issue 2. 1985-04-26. PMID:6335691. |
these results are compatible with the view that mptp has no affinity to dopamine receptors but is preferentially taken up into dopaminergic nerve terminals by the nomifensine-sensitive uptake system where it reaches a concentration sufficient to inhibit intraneuronal monoamine oxidase (mao). |
1985-04-26 |
2023-08-12 |
rat |
| A M Nielsen, G E Bisgar. Differential effects on phrenic output of two dopamine agonists, apomorphine and bromocriptine. European journal of pharmacology. vol 106. issue 1. 1985-04-26. PMID:6529974. |
these results confirm previous evidence for the existence of dopaminergic receptors within the central nervous system, which are inaccessible to exogenous dopamine, and which can alter timing as well as amplitude characteristics of the integrated phrenic neurogram. |
1985-04-26 |
2023-08-12 |
Not clear |
| I Fazekas, H Medzihradszky-Schweiger, G Rappay, Z Acs, M Fekete, A Gyéva. Responsiveness of intermediate lobe cells to neural mediators in culture. Experimental and clinical endocrinology. vol 84. issue 3. 1985-04-18. PMID:6098487. |
the inhibition is probably mediated by specific dopaminergic receptors, since simultaneously added haloperidol prevented the dopamine induced hormone release inhibition. |
1985-04-18 |
2023-08-12 |
rat |
| T F Freund, J P Bolam, A Björklund, U Stenevi, S B Dunnett, J F Powell, A D Smit. Efferent synaptic connections of grafted dopaminergic neurons reinnervating the host neostriatum: a tyrosine hydroxylase immunocytochemical study. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 5. issue 3. 1985-04-12. PMID:2857778. |
in adult rats with a unilateral 6-hydroxydopamine-induced destruction of the nigrostriatal dopamine (da) pathway, grafts of embryonic substantia nigra can establish a new dopaminergic terminal fiber plexus in the previously denervated neostriatum and compensate for some of the behavioral deficits induced by the nigrostriatal lesion. |
1985-04-12 |
2023-08-11 |
rat |
| A D Zharikova, O V Godukhi. [Presynaptic autoregulation of dopamine release]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. vol 71. issue 1. 1985-04-11. PMID:2982672. |
perfusion with dopamine--containing medium (10(-4) m) leads to a decrease in the amplitude of eps recorded in the neostriatum upon electrical stimulation of zona compacta of substantia nigra, indicating that dopamine release from dopaminergic terminals of nigro--striatal neurons decreases in response to ap. |
1985-04-11 |
2023-08-11 |
rat |
| B Muller, T Harris, C Bel. Characterization of chromaffin-like cells in the canine sympathetic chain by enzyme immunohistochemistry and quantitation of their distribution. Neuroscience. vol 13. issue 3. 1985-04-02. PMID:6527782. |
some of the paravertebral sympathetic ganglia of the dog contain relatively large amounts of dopamine, which we have suggested previously is localized in dopaminergic neurones. |
1985-04-02 |
2023-08-12 |
dog |
| R L Cooper, I J Constable, L Davidso. Catecholamines in aqueous humour of glaucoma patients. Australian journal of ophthalmology. vol 12. issue 4. 1985-04-01. PMID:6152150. |
the unexplained and new finding of dopamine in the aqueous humour may have some bearing on the action of dopaminergic drugs for the treatment of glaucoma. |
1985-04-01 |
2023-08-12 |
Not clear |
| B K Madras, P Seema. Drug potencies on partially purified brain D2 dopamine receptors. Journal of neurochemistry. vol 44. issue 3. 1985-03-25. PMID:2579201. |
to examine the sensitivities of partially purified dopamine receptors to various dopaminergic agonists and antagonists, canine brain striatum dopamine receptors were enriched by isoelectric focusing. |
1985-03-25 |
2023-08-11 |
Not clear |