| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I Leroux-Nicollet, J Costenti. In vivo and in vitro autoradiographic labelling of central dopaminergic systems with [3H]GBR12783 in rodents. Neuroscience letters. vol 95. issue 1-3. 1989-03-29. PMID:2976132. |
labelling of central dopaminergic systems with the dopamine uptake inhibitor [3h]gbr12783 was performed in vivo in mice by i.v. |
1989-03-29 |
2023-08-11 |
mouse |
| M K Si. Tuberoinfundibular transport of intrahypothalamic-administered dopamine in normo- and hypertensive rats. Clinical and experimental hypertension. Part A, Theory and practice. vol 10. issue 6. 1989-03-28. PMID:3224434. |
these findings suggest that hypertension and the alleged reduced central dopaminergic activity in the shr is not related to the transport of dopamine in the tuberoinfundibular tract. |
1989-03-28 |
2023-08-11 |
rat |
| S J O'Dell, J F Marshal. Transport of [3H]mazindol binding sites in mesostriatal dopamine axons. Brain research. vol 460. issue 2. 1989-03-27. PMID:3147121. |
such lesions produce accumulations of high-affinity dopamine uptake sites (as measured by [3h]mazindol binding) and acetylcholinesterase proximal to the injection, suggesting that at least a portion of the [3h]mazindol binding and acetylcholinesterase activity seen in the striatum is located presynaptically on the mesostriatal dopaminergic fibers. |
1989-03-27 |
2023-08-11 |
Not clear |
| L Pierot, C Desnos, J Blin, R Raisman, D Scherman, F Javoy-Agid, M Ruberg, Y Agi. D1 and D2-type dopamine receptors in patients with Parkinson's disease and progressive supranuclear palsy. Journal of the neurological sciences. vol 86. issue 2-3. 1989-03-22. PMID:2975699. |
the densities of d1- and d2-type dopamine receptors were measured with [3h]sch23390 and [3h]spiperone, in the caudate nucleus and putamen of a large series of patients with parkinson's disease or progressive supranuclear palsy, in relation to markers of dopaminergic and cholinergic innervation of the striatum ([3h]dihydrotetrabenazine binding and choline acetyltransferase activity). |
1989-03-22 |
2023-08-11 |
Not clear |
| M Takahashi, Y Miura, N Sano, T Ohzeki, T Sugawara, T Noshiro, Y Meguro, H Watanabe, K Shimizu, K Hane. [Effects of high sodium diet on dopaminergic mechanism in normal and hypertensive subjects]. Nihon Naibunpi Gakkai zasshi. vol 64. issue 11. 1989-03-21. PMID:3065095. |
to investigate the effects of dietary sodium on the peripheral dopaminergic mechanism, changes of unconjugated plasma dopamine(da) and its related humoral factors were studied in 8 patients with essential hypertension(eh) and 8 age-matched normal controls(n) while they were receiving ordinary meals (na, 130-180 meq daily) followed by higher sodium (250-300 meq daily) diets for a week. |
1989-03-21 |
2023-08-11 |
human |
| M Hirai, N Kitamura, T Hashimoto, T Nakai, T Mita, O Shirakawa, T Yamadori, T Amano, S A Noguchi-Kuno, C Tanak. [3H]GBR-12935 binding sites in human striatal membranes: binding characteristics and changes in parkinsonians and schizophrenics. Japanese journal of pharmacology. vol 47. issue 3. 1989-03-21. PMID:3221529. |
one site is partially sodium-dependent and appears to be associated with a high-affinity dopamine uptake system on dopaminergic nerve terminals. |
1989-03-21 |
2023-08-11 |
mouse |
| T Aimoto, B H Rohde, G C Chiou, J K Laube. N-acetyltransferase activity and melatonin level in the eyes of glaucomatous chickens. Journal of ocular pharmacology. vol 1. issue 2. 1989-03-17. PMID:3880072. |
no statistical differences in choline acetyltransferase activity, adrenergic transmitter levels or dopamine concentrations could be found in tissues of liag eyes vs control eyes, indicating that cholinergic, adrenergic and dopaminergic mechanisms are probably not involved in liag. |
1989-03-17 |
2023-08-11 |
human |
| S Hjorth, D Clark, A Carlsso. Dopamine (DA) autoreceptor efficacy of 3-PPP enantiomers after short-term synaptic DA deprivation. European journal of pharmacology. vol 152. issue 3. 1989-03-16. PMID:3146512. |
we have compared the central dopamine (da) autoreceptor-stimulatory properties of the 'atypical' da agonist, (-)-3-ppp, its (+)-antipode and the reference da agonist, apomorphine, following a 5 or an 18 h interruption of synaptic dopaminergic transmission by means of reserpine. |
1989-03-16 |
2023-08-11 |
rat |
| A Randrup, G Sørensen, M Kobayash. Stereotyped behaviour in animals induced by stimulant drugs or by a restricted cage environment: relation to disintegrated behaviour, brain dopamine and psychiatric disease. Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology. vol 8. issue 2. 1989-03-09. PMID:3064493. |
strong evidence indicates that the effect of stimulant drugs is mediated through a primary effect on brain dopamine, and further knowledge is now being acquired through studies on dopamine receptors, tolerance and reverse tolerance to amphetamines and the neural connections of dopaminergic sub-systems with other sub-systems in the brain. |
1989-03-09 |
2023-08-11 |
Not clear |
| E K Syvälaht. Dopamine receptors and psychiatric drug treatment. Annals of clinical research. vol 20. issue 5. 1989-03-06. PMID:2905878. |
sulpiride and clozapine are examples of atypical neuroleptic compounds that have quite different profile of action, the former having strong and selective antidopaminergic action, the latter combining a number of non- dopaminergic mechanisms with rather slight effects on dopamine receptors. |
1989-03-06 |
2023-08-11 |
Not clear |
| C Pifl, L Pichler, W Kobinger, O Hornykiewic. The dopamine autoreceptor agonist, B-HT 920, preferentially reduces brain dopamine release in vivo: biochemical indices of brain dopamine, noradrenaline and serotonin in ventriculocisternal perfusates in the cat. European journal of pharmacology. vol 153. issue 1. 1989-03-03. PMID:2463928. |
b-ht 920 (6-allyl-2-amino-5,6,7,8-tetrahydro-4h-thiazolo[4,5-d]azepine), a candidate for selective dopamine (da) autoreceptor agonist activity, was tested for its interactions with biochemical parameters of brain dopaminergic, noradrenergic and serotoninergic systems as measured in ventriculocisternal perfusates of chloralose-anaesthetized cats. |
1989-03-03 |
2023-08-11 |
cat |
| J G Hensler, M L Dubocovic. GABAergic modulation of D-1 dopamine receptor-mediated 3H-acetylcholine release from rabbit retina. Naunyn-Schmiedeberg's archives of pharmacology. vol 337. issue 6. 1989-03-02. PMID:3216899. |
endogenous dopamine, released from dopaminergic amacrine neurons by the indirect amines tyramine or d-amphetamine evoked the calcium-dependent release of 3h-acetylcholine from rabbit retina. |
1989-03-02 |
2023-08-11 |
rabbit |
| R F Cox, B L Waszcza. Differences in dopamine receptor reserve for N-n-propylnorapomorphine enantiomers: single unit recording studies after partial inactivation of receptors by N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline. Molecular pharmacology. vol 35. issue 1. 1989-03-01. PMID:2563304. |
for example, (s)-(+)npa had weak dopaminergic agonist potency, in that it could slow and ultimately stop firing of substantia nigra and ventral tegmental area dopamine neurons. |
1989-03-01 |
2023-08-11 |
rat |
| b' T R Pchelintseva, V E Pogorely\\xc4\\xad, M D Gaevy\\xc4\\xa. [The participation of dopamine in the vascular reactions and metabolic processes of the brain]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. vol 74. issue 9. 1989-03-01. PMID:3215328.' |
the effect of dopamine on blood circulation and cerebral metabolism mediated through adrenergic (alpha- and beta-) and dopaminergic structures, is discussed. |
1989-03-01 |
2023-08-11 |
Not clear |
| R Sandy. Dopamine and insulin interact to modulate in vitro glucose transport in rat adipocytes. The International journal of neuroscience. vol 43. issue 1-2. 1989-02-28. PMID:3063682. |
these effects of dopamine on glucose transport may be relevant to the pathophysiology of parkinson's disease and other neuropsychiatric conditions in which abnormalities of dopaminergic functions are thought to be of major pathogenic importance. |
1989-02-28 |
2023-08-11 |
rat |
| A Kalsbeek, J P De Bruin, M G Feenstra, M A Matthijssen, H B Uyling. Neonatal thermal lesions of the mesolimbocortical dopaminergic projection decrease food-hoarding behavior. Brain research. vol 475. issue 1. 1989-02-28. PMID:3214729. |
these results imply that the integrity of the dopaminergic projection to the prefrontal cortex is essential for food-hoarding behavior to occur and that food-hoarding activity is not spared after neonatal depletion of dopamine. |
1989-02-28 |
2023-08-11 |
rat |
| G Bagetta, E Priolo, G Nistic. Dopamine D-2 receptors in the ventral tegmental area mediate behavioural and electrocortical sleep of dopaminergic drugs in rats. Pharmacological research communications. vol 20. issue 12. 1989-02-23. PMID:2905475. |
dopamine d-2 receptors in the ventral tegmental area mediate behavioural and electrocortical sleep of dopaminergic drugs in rats. |
1989-02-23 |
2023-08-11 |
rat |
| O Giorgi, M G Corda, G Biggi. Ro 15-4513, like anxiogenic beta-carbolines, increases dopamine metabolism in the prefrontal cortex of the rat. European journal of pharmacology. vol 156. issue 1. 1989-02-21. PMID:3208840. |
the effects of ro 15-4513, fg 7142 and beta-ccm on the activity of the mesocortical dopaminergic system were examined by measuring the changes in the content of the principal dopamine (da) metabolite, dihydroxyphenylacetic acid (dopac) in the prefrontal cortex of the rat. |
1989-02-21 |
2023-08-11 |
rat |
| H Imai, T Nakamura, K Endo, H Narabayash. Hemiparkinsonism in monkeys after unilateral caudate nucleus infusion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): behavior and histology. Brain research. vol 474. issue 2. 1989-02-21. PMID:3264746. |
systematically administered 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) is biotransformed into 1-methyl-4-phenylpyridinium ion (mpp+), which enters dopaminergic neurons via the dopamine uptake system to destroy nigral cells. |
1989-02-21 |
2023-08-11 |
monkey |
| b' G Bagetta, G De Sarro, E Priolo, G Nistic\\xc3\\xb. Ventral tegmental area: site through which dopamine D2-receptor agonists evoke behavioural and electrocortical sleep in rats. British journal of pharmacology. vol 95. issue 3. 1989-02-16. PMID:2974741.' |
the present experiments provide evidence suggesting that stimulation of dopamine d2-receptors located at the cell body level and/or the dendrites of dopaminergic neurones in the vta may represent the mechanism through which apomorphine or (+)-3ppp exert their soporific effects in rats. |
1989-02-16 |
2023-08-11 |
rat |