| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Yoshida, M Tanak. Existence of new dopaminergic terminal plexus in the rat spinal cord: assessment by immunohistochemistry using anti-dopamine serum. Neuroscience letters. vol 94. issue 1-2. 1989-05-16. PMID:3071747. |
dopamine (da)-immunoreactive nerve terminals occurred along the ventral motor column throughout all spinal levels, as well as previously noted presumed dopaminergic nerve terminals within the intermediolateral cell column, the dorsal horn and in the area surrounding the central canal. |
1989-05-16 |
2023-08-11 |
rat |
| H S Aabec. [Tourette syndrome. New aspects on pharmacological treatment]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke. vol 109. issue 9. 1989-05-12. PMID:2565050. |
the two most utilized agents, haloperidol and pimozide, decrease central dopaminergic activity by blocking dopamine receptors and have been shown to improve the symptomatology of tourette syndrome. |
1989-05-12 |
2023-08-11 |
Not clear |
| D W Teller, P Deveny. Bromocriptine in cocaine withdrawal--does it work? The International journal of the addictions. vol 23. issue 11. 1989-05-05. PMID:3069753. |
in an uncontrolled trial of 25 heavy cocaine users, measurements of pre- and post-bromocriptine serum prolactin levels-as indicators of inhibitory dopaminergic control-did not suggest dopamine depletion. |
1989-05-05 |
2023-08-11 |
Not clear |
| A S Breathnac. Extra-cutaneous melanin. Pigment cell research. vol 1. issue 4. 1989-05-05. PMID:3070524. |
neuromelanin derives from dopamine, and is found in dopaminergic neurons widely distributed throughout the brain-stem and hypothalamus, and which project to the striatum and limbic system. |
1989-05-05 |
2023-08-11 |
Not clear |
| A Kalsbeek, J P de Bruin, M A Matthijssen, H B Uyling. Ontogeny of open field activity in rats after neonatal lesioning of the mesocortical dopaminergic projection. Behavioural brain research. vol 32. issue 2. 1989-05-04. PMID:2923656. |
in order to examine the effect of neonatal depletion of the dopaminergic mesocortical projection on the development of a prefrontal cortex-mediated behaviour the ontogeny of open field behaviour was studied after neonatal depletion of cortical dopamine. |
1989-05-04 |
2023-08-11 |
rat |
| A Kalsbeek, J P de Bruin, M A Matthijssen, H B Uyling. Ontogeny of open field activity in rats after neonatal lesioning of the mesocortical dopaminergic projection. Behavioural brain research. vol 32. issue 2. 1989-05-04. PMID:2923656. |
more extensive vta lesions produced an almost complete depletion of dopamine in the prefrontal cortex, but also affected the dopaminergic innervation of the nucleus accumbens, and resulted in a permanent hypoactivity in locomotor and exploratory behaviour in the open field. |
1989-05-04 |
2023-08-11 |
rat |
| P Herridge, M S Gol. Pharmacological adjuncts in the treatment of opioid and cocaine addicts. Journal of psychoactive drugs. vol 20. issue 3. 1989-05-03. PMID:3069983. |
these agents potentiate dopaminergic transmission and in so doing tend to counter the dopamine depletion effect of prolonged cocaine use. |
1989-05-03 |
2023-08-11 |
Not clear |
| S Iyengar, A Hausler, H S Kim, M Marien, C A Altar, P L Woo. The dopamine autoreceptor agonist, (+/-)-trans-1,3,4,4a5,10b-hexahydro-4-propyl-2H [1]benzopyrano [3,4-b] pyridin-9-ol hydrochloride (CGS 15855A), modulates striatal dopamine metabolism and prolactin release. Neuropharmacology. vol 28. issue 1. 1989-04-28. PMID:2522597. |
these data suggest that cgs 15855a is a selective dopamine autoreceptor agonist which preferentially stimulates d2 receptors on lactotrophs and dopaminergic neurons as compared to d2 receptors on cholinergic interneurons in the striatum. |
1989-04-28 |
2023-08-11 |
Not clear |
| M Diana, S J Young, P M Grove. Modulation of dopaminergic terminal excitability by D1 selective agents. Neuropharmacology. vol 28. issue 1. 1989-04-28. PMID:2522599. |
the results suggest that the terminal excitability of antidromically identified nigro-striatal dopaminergic neurons can be modified with specific dopamine d1 receptor agents via a receptor mediated mechanism. |
1989-04-28 |
2023-08-11 |
Not clear |
| M Diana, S J Young, P M Grove. Modulation of dopaminergic terminal excitability by D1 selective agents. Neuropharmacology. vol 28. issue 1. 1989-04-28. PMID:2522599. |
previous studies from this laboratory have demonstrated that the electrical excitability of nigro-striatal dopaminergic terminals is reduced by the dopaminomimetics apomorphine and amphetamine and is increased by the dopamine antagonists haloperidol, fluphenazine and sulpiride (groves, fenster, tepper, nakamura, and young 1981; tepper, nakamura, young and groves 1984). |
1989-04-28 |
2023-08-11 |
Not clear |
| J F Lipinski, P E Keck, S L McElro. Beta-adrenergic antagonists in psychosis: is improvement due to treatment of neuroleptic-induced akathisia? Journal of clinical psychopharmacology. vol 8. issue 6. 1989-04-26. PMID:2906947. |
it is possible that the mechanism of action for the anti-akathisia and antipsychotic effects of beta-adrenergic antagonists may be due to enhancement of the firing rate of dopamine neurons in the ventral tegmental area, with subsequent increased release of dopamine and decreased interference with dopaminergic neurotransmission. |
1989-04-26 |
2023-08-11 |
Not clear |
| B M Snape, E Pileblad, A Ekman, T Magnusson, A Carlsson, J Enge. The effects of 1-methyl-4-phenylpyridinium ion (MPP+) on the efflux and metabolism of endogenous dopamine in rat striatal slices. The Journal of pharmacy and pharmacology. vol 40. issue 9. 1989-04-26. PMID:2907028. |
the accumulation of mpp+ was reduced in the presence of 10 microm of the selective dopamine uptake inhibitor gbr 12909 (-50%) or by destruction of the dopaminergic terminals by complete hemisection of the forebrain 4 days before the experiments (-75%). |
1989-04-26 |
2023-08-11 |
rat |
| R A Wise, P P Rompr. Brain dopamine and reward. Annual review of psychology. vol 40. 1989-04-24. PMID:2648975. |
one thing is clear: dopamine is not the only reward transmitter, and dopaminergic neurons are not the final common path for all rewards. |
1989-04-24 |
2023-08-11 |
Not clear |
| R A Wise, P P Rompr. Brain dopamine and reward. Annual review of psychology. vol 40. 1989-04-24. PMID:2648975. |
it is not consistent with the dopamine hypothesis that dopamine-independent reward sites should exist in these areas, since any reward signals carried to nucleus accumbens or frontal cortex by dopamine fibers would-unless we are to believe that reward "happens" at these sites-have to be carried to the next stage of the circuit by nondopaminergic fibers (there are no dopaminergic cell bodies in any of the dopamine terminal areas). |
1989-04-24 |
2023-08-11 |
Not clear |
| M Sakai, K Kani, M Yoshida, I Nagats. Dopaminergic cells in the superior cervical ganglion of the rat: light and electron microscopic study using an antibody against dopamine. Neuroscience letters. vol 96. issue 2. 1989-04-24. PMID:2927719. |
dopaminergic cells in the superior cervical ganglion of the rat: light and electron microscopic study using an antibody against dopamine. |
1989-04-24 |
2023-08-11 |
rat |
| H Nissbrandt, E Sundström, G Jonsson, S Hjorth, A Carlsso. Synthesis and release of dopamine in rat brain: comparison between substantia nigra pars compacts, pars reticulata, and striatum. Journal of neurochemistry. vol 52. issue 4. 1989-04-21. PMID:2564423. |
dopamine (da) is synthesized and released not only from the terminals of the nigrostriatal dopaminergic neuronal pathway, but also from the dendrites in the substantia nigra. |
1989-04-21 |
2023-08-11 |
rat |
| O Serri, H Beauregard, M Somma, R Comtois, N Jilwan, J Hard. Defective dopaminergic regulation of prolactin secretion in patients with hyperprolactinemia. Clinical and investigative medicine. Medecine clinique et experimentale. vol 11. issue 6. 1989-04-13. PMID:3229037. |
in order to evaluate the dopaminergic control of the lactotroph, we examined the plasma prolactin response to metoclopramide (a dopamine receptor blocker, 10 mg iv bolus) and to dopamine (1 microgram/kg/min iv infusion for 120 min) in 52 hyperprolactinemic female patients and 19 healthy volunteer women. |
1989-04-13 |
2023-08-11 |
human |
| Y K Gupta, Anita Chugh, S D Set. Opposing effect of apomorphine on antinociceptive activity of morphine: a dose-dependent phenomenon. Pain. vol 36. issue 2. 1989-04-05. PMID:2919107. |
the attenuation of morphine antinociception thus appears to be due to decreased dopaminergic activity as a result of preferential dopamine autoreceptor stimulation by a low dose of apomorphine, whereas potentiation with a high dose of apomorphine is caused by enhanced dopaminergic activity via postsynaptic receptor stimulation. |
1989-04-05 |
2023-08-11 |
rat |
| J Knol. The striatal dopamine dependency of life span in male rats. Longevity study with (-)deprenyl. Mechanisms of ageing and development. vol 46. issue 1-3. 1989-04-05. PMID:3147347. |
it was established by the aid of (-)deprenyl, a highly specific chemical tool, which increases superoxide dismutase activity in the striatum, facilitates the activity of the nigrostriatal dopaminergic neurons with utmost selectivity, and protects these neurons from their age-related decay, that the efficiency of a male rat in behavioral tests, as well as the duration of its life are striatal dopamine dependent functions. |
1989-04-05 |
2023-08-11 |
rat |
| M D Schechter, J W Boj. CGS 10746B is able to attenuate the effects of amphetamine: further evidence for dopaminergic mediation. Pharmacology, biochemistry, and behavior. vol 30. issue 4. 1989-04-04. PMID:2906435. |
this antagonism was shown to be dose-responsive and constitutes a third mechanism, i.e., dopamine release inhibition, that evidences the dopaminergic mediation of amphetamine in the discriminative paradigm. |
1989-04-04 |
2023-08-11 |
rat |