| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M M Mouradian, I J Heuser, F Baronti, T N Chas. Modification of central dopaminergic mechanisms by continuous levodopa therapy for advanced Parkinson's disease. Annals of neurology. vol 27. issue 1. 1990-02-23. PMID:2301923. |
these results suggest that changes in central dopaminergic mechanisms contributing to motor complications in advanced parkinson's disease can be modified by procedures that provide continuous dopamine replacement. |
1990-02-23 |
2023-08-11 |
Not clear |
| Y G Gao, V J Ram, A Campbell, N S Kula, R J Baldessarini, J L Neumeye. Synthesis and structural requirements of N-substituted norapomorphines for affinity and activity at dopamine D-1, D-2, and agonist receptor sites in rat brain. Journal of medicinal chemistry. vol 33. issue 1. 1990-02-22. PMID:2136919. |
a series of n-substituted analogues of (r)-(-)-norapomorphine were synthesized to study the optimal structural requirements of the n-alkyl side chain to interact with d-1 and d-2 dopaminergic receptors as well as dopamine (da) agonist binding sites. |
1990-02-22 |
2023-08-11 |
rat |
| L H Gold, M A Geyer, G F Koo. Neurochemical mechanisms involved in behavioral effects of amphetamines and related designer drugs. NIDA research monograph. vol 94. 1990-02-21. PMID:2514360. |
this dopaminergic substrate for psychostimulant effects appears selective for the indirect sympathomimetics in that dopamine lesions to the region of the nucleus accumbens do not block caffeine, scopolamine, heroin, or csf-induced locomotor activation (swerdlow and koob 1985; vaccarino et al. |
1990-02-21 |
2023-08-11 |
rat |
| J M Danger, I Perroteau, M F Franzoni, S Saint-Pierre, A Fasolo, H Vaudr. Innervation of the pars intermedia and control of alpha-melanotropin secretion in the newt. Neuroendocrinology. vol 50. issue 5. 1990-02-21. PMID:2514395. |
using a specific antiserum to dopamine, these fibers appeared to be mainly dopaminergic in nature. |
1990-02-21 |
2023-08-11 |
Not clear |
| Y K Fung, J A Reed, Y S La. Prenatal cocaine exposure fails to modify neurobehavioral responses and the striatal dopaminergic system in newborn rats. General pharmacology. vol 20. issue 5. 1990-02-21. PMID:2606336. |
the effects of cocaine on locomotor activity and striatal dopaminergic receptors and dopamine turnover were studied in rat pups exposed to cocaine (30 mg/kg/day) throughout the entire gestational period. |
1990-02-21 |
2023-08-11 |
rat |
| Y K Fung, J A Reed, Y S La. Prenatal cocaine exposure fails to modify neurobehavioral responses and the striatal dopaminergic system in newborn rats. General pharmacology. vol 20. issue 5. 1990-02-21. PMID:2606336. |
no change in the characteristics of dopaminergic receptors and the rate of dopamine turnover was detected in the striatum. |
1990-02-21 |
2023-08-11 |
rat |
| S P Siva. D1 dopamine receptor-mediated substance P depletion in the striatonigral neurons of rats subjected to neonatal dopaminergic denervation: implications for self-injurious behavior. Brain research. vol 500. issue 1-2. 1990-02-20. PMID:2481560. |
d1 dopamine receptor-mediated substance p depletion in the striatonigral neurons of rats subjected to neonatal dopaminergic denervation: implications for self-injurious behavior. |
1990-02-20 |
2023-08-11 |
rat |
| T Matsumoto, T P Obrenovitch, G S Sarna, L Symo. [Extracellular concentration of dopamine and dopamine metabolites in the rat striatum during cerebral ischemia and reperfusion]. No to shinkei = Brain and nerve. vol 41. issue 10. 1990-02-13. PMID:2605040. |
many data suggest that the presence of dopamine (da) is a prerequisite for the development of neuronal damage in the striatum; neural injury could be initiated by a massive release from dopaminergic nerve terminals during ischemia. |
1990-02-13 |
2023-08-11 |
rat |
| J Engele, C Pilgrim, I Reiser. Sexual differentiation of mesencephalic neurons in vitro: effects of sex and gonadal hormones. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 7. issue 6. 1990-02-06. PMID:2603757. |
it was ascertained by use of specific inhibitors and by autoradiography that the uptake of [3h]dopamine was restricted to neurons immunoreactive for tyrosine hydroxylase and that these neurons have dopaminergic properties. |
1990-02-06 |
2023-08-11 |
rat |
| J S Bevan, C W Burke, M M Esiri, C B Adams, M Ballabio, M Nissim, G Fagli. Studies of two thyrotrophin-secreting pituitary adenomas: evidence for dopamine receptor deficiency. Clinical endocrinology. vol 31. issue 1. 1990-01-31. PMID:2598481. |
the results suggest that the dopaminergic resistance typical of most tsh-secreting pituitary adenomas may be due to altered or absent membrane-bound dopamine receptors. |
1990-01-31 |
2023-08-11 |
Not clear |
| L A Matsuda, G R Hanson, J W Gib. Neurochemical effects of amphetamine metabolites on central dopaminergic and serotonergic systems. The Journal of pharmacology and experimental therapeutics. vol 251. issue 3. 1990-01-30. PMID:2600821. |
because p-oha is metabolized to p-ohnor via dopamine beta-hydroxylase present in noradrenergic neurons, the direct effects of these compounds on dopaminergic and serotonergic variables can be observed in rats which receive intrastriatal drug treatment. |
1990-01-30 |
2023-08-11 |
rat |
| M Clagett-Dame, R Schoenleber, C Chung, J F McKelv. Preparation of an affinity chromatography matrix for the selective purification of the dopamine D2 receptor from bovine striatal membranes. Biochimica et biophysica acta. vol 986. issue 2. 1990-01-24. PMID:2531613. |
dopamine d2 receptor was eluted from the affinity resin using a competing dopaminergic antagonist molecule, haloperidol. |
1990-01-24 |
2023-08-11 |
cattle |
| J P Tassi. [Neurotensin, dopamine and mode of action of neuroleptics]. L'Encephale. vol 15. issue 5. 1990-01-22. PMID:2574102. |
indeed, by blocking dopamine receptors, neuroleptics might bring about long-term and heterogeneous changes in the transmission of non dopaminergic systems in those projection areas possessing dopamine receptors. |
1990-01-22 |
2023-08-11 |
Not clear |
| R G MacKenzie, M K Stachowiak, M J Zigmon. Dopaminergic inhibition of striatal acetylcholine release after 6-hydroxydopamine. European journal of pharmacology. vol 168. issue 1. 1990-01-11. PMID:2511032. |
these findings indicate that dopamine, acting at the dopamine d-2 receptor, normally exerts an inhibitory influence over acetylcholine release in striatum, that after partial injury the dopaminergic influence over acetylcholine release can recover with time, and that the recovery involves processes other than changes in the number of d-2 receptors. |
1990-01-11 |
2023-08-11 |
rat |
| P Coruzzi, A Novarini, L Musiari, C Ravanetti, S Ghielmi, A Rodella, A Montanar. The antinatriuretic effect of dopaminergic blockade during volume expansion is independent of circulating atrial natriuretic factor. Clinical science (London, England : 1979). vol 77. issue 5. 1990-01-11. PMID:2531052. |
dopamine blockade is able to blunt significantly both water immersion-induced natriuresis and plasma aldosterone suppression, independently of the marked elevation of circulating atrial natriuretic factor, via a mechanism involving type 2 dopaminergic receptors. |
1990-01-11 |
2023-08-11 |
human |
| T Beck, J Wenzel, K Kuschinsky, J Krieglstei. Morphine-induced alterations of local cerebral glucose utilization in the basal ganglia of rats. Brain research. vol 497. issue 2. 1990-01-11. PMID:2684341. |
part of these effects might be, in addition, due to an activation of dopaminergic neurons, since dopamine mainly acts as an inhibitory neurotransmitter. |
1990-01-11 |
2023-08-11 |
rat |
| C Owman, K Fuxe, A M Janson, J Kåhrströ. Studies of protective actions of nicotine on neuronal and vascular functions in the brain of rats: comparison between sympathetic noradrenergic and mesostriatal dopaminergic fiber systems, and the effect of a dopamine agonist. Progress in brain research. vol 79. 1990-01-10. PMID:2573912. |
studies of protective actions of nicotine on neuronal and vascular functions in the brain of rats: comparison between sympathetic noradrenergic and mesostriatal dopaminergic fiber systems, and the effect of a dopamine agonist. |
1990-01-10 |
2023-08-11 |
rat |
| C Owman, K Fuxe, A M Janson, J Kåhrströ. Studies of protective actions of nicotine on neuronal and vascular functions in the brain of rats: comparison between sympathetic noradrenergic and mesostriatal dopaminergic fiber systems, and the effect of a dopamine agonist. Progress in brain research. vol 79. 1990-01-10. PMID:2573912. |
it is concluded that nicotine, mainly through its protective action on the meso-striatal dopaminergic system, is able to improve striatal glucose utilization and associated blood flow, probably reflecting a tendency to amelioration of neurotransmission function of surviving terminals belonging to the nigro-striatal dopamine neurons. |
1990-01-10 |
2023-08-11 |
rat |
| M V Milanés, J A Martínez, M L Varga. Influence of dopaminergic and noradrenergic systems on the release of opioid peptides in guinea-pig ileum. The Journal of pharmacy and pharmacology. vol 41. issue 9. 1990-01-08. PMID:2573704. |
it is concluded that the effect of neuroleptics on the release of opioids from myenteric plexus is due to the blockade of dopamine receptors, and that interruption of dopaminergic transmission produces an increase in opioid release at this level. |
1990-01-08 |
2023-08-11 |
Not clear |
| H M Siragy, R A Felder, N L Howell, R L Chevalier, M J Peach, R M Care. Intrarenal dopamine-1 receptors control renal function. Transactions of the Association of American Physicians. vol 101. 1990-01-05. PMID:2978636. |
dopamine receptors are classified to da-1 and da-2 and are characterized in renal tissue by radioligand binding and by the response of renal adenylate cyclase to dopaminergic agonists and antagonists. |
1990-01-05 |
2023-08-11 |
Not clear |