| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N B Mercuri, P Calabresi, G Bernard. The electrophysiological actions of dopamine and dopaminergic drugs on neurons of the substantia nigra pars compacta and ventral tegmental area. Life sciences. vol 51. issue 10. 1992-09-29. PMID:1355254. |
in this review, we will briefly examine the literature concerning the physiological and behavioural responses caused by dopamine and dopaminergic agents on the dopaminergic neurons of the ventral mesencephalon. |
1992-09-29 |
2023-08-11 |
Not clear |
| N B Mercuri, P Calabresi, G Bernard. The electrophysiological actions of dopamine and dopaminergic drugs on neurons of the substantia nigra pars compacta and ventral tegmental area. Life sciences. vol 51. issue 10. 1992-09-29. PMID:1355254. |
our conclusion suggests that the electrophysiological actions of dopamine and dopamine-related drugs on dopaminergic cells in the ventral mesencephalon might be indicative of the pharmacological effects of these agents on the brain. |
1992-09-29 |
2023-08-11 |
Not clear |
| W D Le, J R Bostwick, S H Appe. Use of [3H]-GBR12935 to measure dopaminergic nerve terminal growth into the developing rat striatum. Brain research. Developmental brain research. vol 67. issue 2. 1992-09-25. PMID:1511527. |
in this study we determined the temporal association between the appearance of the dopamine transporter, measured by 1-[2-(diphenyl-methoxy)ethyl]-4-(3- phenylpropyl)-piperazine ([3h]-gbr12935), a potent and selective inhibitor of dopamine uptake, and other biochemical markers of dopaminergic nerve terminal growth into the developing striatum. |
1992-09-25 |
2023-08-11 |
rat |
| W D Le, J R Bostwick, S H Appe. Use of [3H]-GBR12935 to measure dopaminergic nerve terminal growth into the developing rat striatum. Brain research. Developmental brain research. vol 67. issue 2. 1992-09-25. PMID:1511527. |
these results indicate that the appearance of a structural, but not optimally functional, dopamine transporter may be the earliest detectable biochemical index of dopaminergic nerve terminal growth into the striatum during development. |
1992-09-25 |
2023-08-11 |
rat |
| M F Olson, B P Schimme. Heterologous desensitization of the human dopamine D1 receptor in Y1 adrenal cells and in a desensitization-resistant Y1 mutant. Molecular endocrinology (Baltimore, Md.). vol 6. issue 7. 1992-09-24. PMID:1354841. |
in the present study, parental y1 cells (y1ds) and the y1dr mutant were transfected with the gene encoding the human dopamine d1 receptor and examined for regulation of adenylyl cyclase by dopaminergic agonists. |
1992-09-24 |
2023-08-11 |
human |
| M F Olson, B P Schimme. Heterologous desensitization of the human dopamine D1 receptor in Y1 adrenal cells and in a desensitization-resistant Y1 mutant. Molecular endocrinology (Baltimore, Md.). vol 6. issue 7. 1992-09-24. PMID:1354841. |
treatment of the y1ds transformants with acth promoted a rapid, homologous desensitization of adenylyl cyclase and had little effect on the responses to dopamine or naf; treatment of y1ds with dopaminergic agonists promoted a slower rate of heterologous desensitization that diminished responsiveness of the adenylyl cyclase system to dopamine, acth, and naf. |
1992-09-24 |
2023-08-11 |
human |
| M F Olson, B P Schimme. Heterologous desensitization of the human dopamine D1 receptor in Y1 adrenal cells and in a desensitization-resistant Y1 mutant. Molecular endocrinology (Baltimore, Md.). vol 6. issue 7. 1992-09-24. PMID:1354841. |
y1dr cells transfected with the dopamine d1 receptor were resistant to the heterologous desensitization of adenylyl cyclase induced by dopaminergic agonists. |
1992-09-24 |
2023-08-11 |
human |
| M S al-Tikriti, R H Roth, R M Kessler, R B Inni. Autoradiographic localization of dopamine D1 and D2 receptors in rat cerebral cortex following unilateral neurotoxic lesions. Brain research. vol 575. issue 1. 1992-09-24. PMID:1387031. |
relative to dopaminergic innervation of cortex, dopamine d1 and d2 receptors may be located on presynaptic terminals and/or postsynaptically on cortical neurons. |
1992-09-24 |
2023-08-11 |
rat |
| E Garcia, C Rios, J Sotel. Ventricular injection of nerve growth factor increases dopamine content in the striata of MPTP-treated mice. Neurochemical research. vol 17. issue 10. 1992-09-24. PMID:1508308. |
the increase of dopamine and homovanillic acid seems to be related to a partial restorative effect of ngf on the damaged dopaminergic cells, since ventricular administration of ngf to normal mice did not increase dopamine or homovanillic acid contents above the levels measured in untreated controls. |
1992-09-24 |
2023-08-11 |
mouse |
| G A Donnan, D G Woodhouse, S J Kaczmarczyk, J E Holder, G Paxinos, P J Chilco, A J Churchyard, R M Kalnins, G C Fabinyi, F A Mendelsoh. Evidence for plasticity of the dopaminergic system in parkinsonism. Molecular neurobiology. vol 5. issue 2-4. 1992-09-23. PMID:1823144. |
a series of compensatory mechanisms within the dopaminergic system have been shown to maintain clinical function in the presence of dopamine loss. |
1992-09-23 |
2023-08-11 |
human |
| T L Horvath, F Naftolin, C Lerant. Beta-endorphin innervation of dopamine neurons in the rat hypothalamus: a light and electron microscopic double immunostaining study. Endocrinology. vol 131. issue 3. 1992-09-22. PMID:1354605. |
these results together with the observation of dopamine innervation of lhrh-producing neurons and progesterone receptor-containing cells indicate that neurons of the hypothalamic dopaminergic system probably mediate opiate effects on hypophyseal hormone secretion. |
1992-09-22 |
2023-08-11 |
rat |
| D Ben-Shachar, G Eshel, P Riederer, M B Youdi. Role of iron and iron chelation in dopaminergic-induced neurodegeneration: implication for Parkinson's disease. Annals of neurology. vol 32 Suppl. 1992-09-18. PMID:1510367. |
recent studies in parkinson's disease suggest that the degeneration of the nigrostriatal melanin-containing dopaminergic neurons results from toxic effects of free radicals, which are generated during dopamine metabolism in the substantia nigra (sn). |
1992-09-18 |
2023-08-11 |
rat |
| R Y Shen, D Asdourian, L A Chiod. Microiontophoretic studies of the effects of D-1 and D-2 receptor agonists on type I caudate nucleus neurons: lack of synergistic interaction. Synapse (New York, N.Y.). vol 11. issue 4. 1992-09-14. PMID:1354398. |
several lines of evidence have suggested there may be a physiologically relevant form of synergistic interaction between d-1 and d-2 dopamine (da) receptors located on postsynaptic neurons in the forebrain that receive a dopaminergic innervation. |
1992-09-14 |
2023-08-11 |
rat |
| M Raiteri, M Marchi, G Bonanno, E Fedele, P Versac. Dopamine release and dopaminergic inhibition of acetylcholine release in rat striatal slices after nigro-striatal hemitransection and parenteral ganglioside administration. European journal of pharmacology. vol 213. issue 1. 1992-09-14. PMID:1499655. |
dopamine release and dopaminergic inhibition of acetylcholine release in rat striatal slices after nigro-striatal hemitransection and parenteral ganglioside administration. |
1992-09-14 |
2023-08-11 |
rat |
| C B Jaeger, P Aebischer, P A Tresco, S R Winn, L A Green. Growth of tumour cell lines in polymer capsules: ultrastructure of encapsulated PC12 cells. Journal of neurocytology. vol 21. issue 7. 1992-09-11. PMID:1500946. |
recent studies indicate that polymer-encapsulated pc12 cells release sufficient amounts of dopamine to significantly alter behavioural paradigms in animals with unilateral lesions of dopaminergic midbrain neurons. |
1992-09-11 |
2023-08-11 |
rat |
| C B Jaeger, P Aebischer, P A Tresco, S R Winn, L A Green. Growth of tumour cell lines in polymer capsules: ultrastructure of encapsulated PC12 cells. Journal of neurocytology. vol 21. issue 7. 1992-09-11. PMID:1500946. |
since dopaminergic pc12 pheochromocytoma cells remain viable in semi-permeable polymer capsules for at least six months, such 'cell-capsules' could provide an alternative to dopamine-secreting embryonic neural grafts in dopamine replacement therapies. |
1992-09-11 |
2023-08-11 |
rat |
| S B Schwarzkopf, T Mitra, J P Brun. Sensory gating in rats depleted of dopamine as neonates: potential relevance to findings in schizophrenic patients. Biological psychiatry. vol 31. issue 8. 1992-09-09. PMID:1643192. |
based on a recent hypothesis of reduced subcortical dopaminergic tone, evidence of early neurodevelopmental deviation, and acoustic startle abnormalities in schizophrenia, we examined acoustic startle in adult animals depleted of dopamine (da) as neonates. |
1992-09-09 |
2023-08-11 |
rat |
| F Veglio, G Pinna, F Rabbia, P Mulatero, L Chianduss. [Primary dexamethasone-suppressible hyperaldosteronism and hyperprolactinemia]. Minerva endocrinologica. vol 17. issue 1. 1992-09-08. PMID:1323053. |
our results showed a lack of dopamine inhibiting aldosterone secretion, despite dopaminergic tone is known to be increased in hyperprolactinemia. |
1992-09-08 |
2023-08-11 |
Not clear |
| M Kobari, Y Fukuuchi, T Shinohara, S Nogawa, K Takahash. Local cerebral blood flow and its response to intravenous levodopa in progressive supranuclear palsy. Comparison with Parkinson's disease. Archives of neurology. vol 49. issue 7. 1992-09-04. PMID:1497499. |
the different lcbf responses to levodopa between patients with psp and those with parkinson's disease may reflect differences in pathologic features, such as in the degree of preservation of nigrostriatal dopaminergic neurons and the distribution and density of dopamine receptors, and are also related to the clinical effectiveness of levodopa therapy. |
1992-09-04 |
2023-08-11 |
Not clear |
| T A Reader, E Molina-Holgado, L Lima, S Boulianne, K M Dewa. Specific [3H]raclopride binding to neostriatal dopamine D2 receptors: role of disulfide and sulfhydryl groups. Neurochemical research. vol 17. issue 8. 1992-09-03. PMID:1379349. |
the properties of the remaining binding sites were examined in competition curves with the physiological substrate dopamine and the dopaminergic antagonist (+)butaclamol. |
1992-09-03 |
2023-08-11 |
rabbit |