| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L T Weiss-Wunder, M F Chessele. Acute and repeated administration of fluphenazine-N-mustard alters levels of tyrosine hydroxylase mRNA in subsets of mesencephalic dopaminergic neurons. Neuroscience. vol 49. issue 2. 1992-12-14. PMID:1359452. |
changes in striatal dopamine turnover and levels of tyrosine hydroxylase messenger rna were examined in mice injected with d2 selective doses of fluphenazine-n-mustard, an irreversible blocker of dopaminergic receptors. |
1992-12-14 |
2023-08-11 |
mouse |
| S Masuko, S Nakajima, Y Nakajim. Dissociated high-purity dopaminergic neuron cultures from the substantia nigra and the ventral tegmental area of the postnatal rat. Neuroscience. vol 49. issue 2. 1992-12-14. PMID:1359454. |
co-existence of dopamine and cholecystokinin was found in about 70% of dopaminergic neurons from the substantia nigra and in about 35% of dopaminergic neurons from the ventral tegmental area. |
1992-12-14 |
2023-08-11 |
rat |
| T C Napier, J J Chroba. Evaluations of ventral pallidal dopamine receptor activation in behaving rats. Neuroreport. vol 3. issue 7. 1992-12-14. PMID:1421116. |
the magnitude of this response was related to the dopamine dose injected and the effect was attenuated by systemic pretreatment with the dopaminergic antagonist, flupentixol. |
1992-12-14 |
2023-08-11 |
rat |
| M J Landr. An overview of cocaethylene, an alcohol-derived, psychoactive, cocaine metabolite. Journal of psychoactive drugs. vol 24. issue 3. 1992-12-11. PMID:1432406. |
with a pharmacologic profile similar to cocaine, it can block the dopamine transporter on dopaminergic presynaptic nerve terminals in the brain. |
1992-12-11 |
2023-08-11 |
mouse |
| G A Hicks, G Henderso. Lack of evidence for coupling of the dopamine D2 receptor to an adenosine triphosphate-sensitive potassium (ATP-K+) channel in dopaminergic neurones of the rat substantia nigra. Neuroscience letters. vol 141. issue 2. 1992-12-11. PMID:1436636. |
lack of evidence for coupling of the dopamine d2 receptor to an adenosine triphosphate-sensitive potassium (atp-k+) channel in dopaminergic neurones of the rat substantia nigra. |
1992-12-11 |
2023-08-11 |
rat |
| M Santiago, B H Westerin. The role of GABA receptors in the control of nigrostriatal dopaminergic neurons: dual-probe microdialysis study in awake rats. European journal of pharmacology. vol 219. issue 2. 1992-12-07. PMID:1330605. |
a microdialysis probe implanted into the substantia nigra was used to infuse gamma-aminobutyric acid-ergic (gabaergic) compounds onto cell bodies/dendrites of dopaminergic neurons, while a second microdialysis probe was used to record the extracellular concentrations of dopamine and 3,4-dihydroxy-phenylacetic acid (dopac) in the ipsilateral striatum. |
1992-12-07 |
2023-08-11 |
rat |
| R R Dawirs, G Teuchert-Nood. Demonstration of dopamine-immunoreactive cells in the proximal convoluted tubule of gerbil (Meriones unguiculatus) kidney. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 40. issue 11. 1992-12-03. PMID:1431057. |
the functional significance of dopamine in these cells is discussed in relation to the present view of renal dopaminergic actions. |
1992-12-03 |
2023-08-11 |
Not clear |
| D J Vandenbergh, A M Persico, G R Uh. A human dopamine transporter cDNA predicts reduced glycosylation, displays a novel repetitive element and provides racially-dimorphic TaqI RFLPs. Brain research. Molecular brain research. vol 15. issue 1-2. 1992-12-02. PMID:1359373. |
we describe a cdna for the human dopamine transporter, which has been implicated in several human disorders linked to dopaminergic function. |
1992-12-02 |
2023-08-11 |
human |
| H Böttcher, G Barnickel, H H Hausberg, A F Haase, C A Seyfried, V Eierman. Synthesis and dopaminergic activity of some 3-(1,2,3,6-tetrahydro-1-pyridylalkyl)indoles. A novel conformational model to explain structure-activity relationships. Journal of medicinal chemistry. vol 35. issue 22. 1992-12-01. PMID:1359142. |
the synthesis and dopaminergic properties of a novel type of dopamine agonist is described. |
1992-12-01 |
2023-08-11 |
Not clear |
| J A Smith, S E Loughlin, F M Lesli. kappa-Opioid inhibition of [3H]dopamine release from rat ventral mesencephalic dissociated cell cultures. Molecular pharmacology. vol 42. issue 4. 1992-12-01. PMID:1359395. |
these results suggest that functional kappa receptors, modulating dopamine release, are localized on the terminals of dopaminergic neurons. |
1992-12-01 |
2023-08-11 |
rat |
| C J Schmidt, C K Black, V L Taylor, G M Fadayel, T M Humphreys, T R Nieduzak, S M Sorense. The 5-HT2 receptor antagonist, MDL 28,133A, disrupts the serotonergic-dopaminergic interaction mediating the neurochemical effects of 3,4-methylenedioxymethamphetamine. European journal of pharmacology. vol 220. issue 2-3. 1992-12-01. PMID:1425989. |
mdma-induced 5-ht release did not reduce the firing rate of dopaminergic neurons as assessed by dopamine depletion following synthesis inhibition with alpha-methyl-p-tyrosine (alpha-mpt). |
1992-12-01 |
2023-08-11 |
rat |
| L W Zhou, S P Zhang, S Welsh, T A Connell, B Weis. Triazolam blocks the initial rotational effects of quinpirole but permits the later developing reduction of dopamine D2-mediated rotational behavior and dopamine D2 receptors. European journal of pharmacology. vol 218. issue 2-3. 1992-11-27. PMID:1358635. |
we conclude that up-regulated dopamine receptors and dopaminergic behaviors can be reversed by the continuous administration of a dopamine receptor agonist and that this reversal can occur without producing an initial exacerbation of dopaminergic responses. |
1992-11-27 |
2023-08-11 |
mouse |
| L Churchill, M C Austin, P W Kaliva. Dopamine and endogenous opioid regulation of picrotoxin-induced locomotion in the ventral pallidum after dopamine depletion in the nucleus accumbens. Psychopharmacology. vol 108. issue 1-2. 1992-11-25. PMID:1410135. |
to investigate the regulation of vp-induced locomotion by the dopaminergic innervation of the nucleus accumbens (na) and the role of opioid receptors in this regulation, dopamine innervation of the na was bilaterally lesioned with 6-hydroxydopamine (6-ohda). |
1992-11-25 |
2023-08-11 |
rat |
| A S Undie, E Friedma. Selective dopaminergic mechanism of dopamine and SKF38393 stimulation of inositol phosphate formation in rat brain. European journal of pharmacology. vol 226. issue 4. 1992-11-23. PMID:1327844. |
selective dopaminergic mechanism of dopamine and skf38393 stimulation of inositol phosphate formation in rat brain. |
1992-11-23 |
2023-08-11 |
rat |
| D Nouel, J Costentin, D Lugrin, P Kitabgi, N Ple, D Davous. Investigations about a direct neurotensin-dopamine interaction by nuclear magnetic resonance study, synaptosomal uptake of dopamine, and binding of neurotensin to its receptors. Journal of neurochemistry. vol 59. issue 5. 1992-11-20. PMID:1328532. |
interactions between dopamine and neurotensin can occur at various levels of the dopaminergic pathways. |
1992-11-20 |
2023-08-11 |
Not clear |
| A Markou, G F Koo. Bromocriptine reverses the elevation in intracranial self-stimulation thresholds observed in a rat model of cocaine withdrawal. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 7. issue 3. 1992-11-19. PMID:1388645. |
since cocaine's rewarding effects are mediated by enhanced dopaminergic neurotransmission in the mesocorticolimbic system, it is possible that a long-acting dopamine agonist might block the withdrawal effects associated with the termination of a prolonged bout of cocaine self-administration. |
1992-11-19 |
2023-08-11 |
rat |
| E Panula-Lehto, M Mäkinen, L Ahte. Effects of taurine, homotaurine and GABA on hypothalamic and striatal dopamine metabolism. Naunyn-Schmiedeberg's archives of pharmacology. vol 346. issue 1. 1992-11-19. PMID:1407006. |
to elucidate the effects of taurine on hypothalamic and striatal dopaminergic neurotransmission we compared its effects to those of gamma-aminobutyric acid (gaba) and homotaurine (a gabaa-receptor agonist) on hypothalamic and striatal concentrations of dopamine (da) and its metabolites, 3,4-dihydroxyphenylacetic acid (dopac), homovanillic acid (hva) and, in the case of striatum, 3-methoxytyramine (3-mt) in rats. |
1992-11-19 |
2023-08-11 |
rat |
| O Meucci, E Landolfi, A Scorziello, M Grimaldi, C Ventra, T Florio, A Avallone, G Schettin. Dopamine and somatostatin inhibition of prolactin secretion from MMQ pituitary cells: role of adenosine triphosphate-sensitive potassium channels. Endocrinology. vol 131. issue 4. 1992-11-13. PMID:1356754. |
conversely, we found that glibenclamide does not modify the dopaminergic inhibition of prl secretion and second messenger systems, suggesting that atp-sensitive potassium channels may not be involved in the inhibitory effect of dopamine on prl release. |
1992-11-13 |
2023-08-11 |
Not clear |
| K Inoue, K Nakazawa, T Watano, M Ohara-Imaizumi, K Fujimori, A Takanak. Dopamine receptor agonists and antagonists enhance ATP-activated currents. European journal of pharmacology. vol 215. issue 2-3. 1992-11-13. PMID:1383001. |
the results suggest that atp-activated channels are modulated by dopaminergic mechanisms, and that this modulation cannot be attributed to any single class of dopamine receptors. |
1992-11-13 |
2023-08-11 |
Not clear |
| M F Piercey, J T Lum, W E Hoffmann, A Carlsson, E Ljung, K Svensso. Antagonism of cocaine's pharmacological effects by the stimulant dopaminergic antagonists, (+)-AJ76 and (+)-UH232. Brain research. vol 588. issue 2. 1992-11-13. PMID:1393576. |
the aminotetralins (+)-aj76 and (+)-uh232 are stimulant dopaminergic antagonists, which may preferentially antagonize autoreceptors of dopamine nerve terminals. |
1992-11-13 |
2023-08-11 |
Not clear |