| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Ouagazzal, M Amalri. Competitive NMDA receptor antagonists do not produce locomotor hyperactivity by a dopamine-dependent mechanism. European journal of pharmacology. vol 294. issue 1. 1997-02-12. PMID:8788425. |
these results show that the locomotor hyperactivity induced by ap-5 was not modified when the dopaminergic activity in the nucleus accumbens was either reduced or enhanced, suggesting that the behavioural effects resulting from the blockade of nmda receptors with the competitive nmda receptor antagonist, ap-5, is not mediated by endogenous dopamine in this brain area. |
1997-02-12 |
2023-08-12 |
rat |
| K S Raevskiĭ, T D Sotnikova, R R Gaĭnetdino. [The brain dopaminergic systems: receptor heterogeneity, functional role and pharmacological regulation]. Uspekhi fiziologicheskikh nauk. vol 27. issue 4. 1997-02-12. PMID:9019922. |
the problem of autoreceptor regulation of dopaminergic neurotransmission, particularly, the processes of dopamine synthesis, release and metabolism has been specially discussed. |
1997-02-12 |
2023-08-12 |
rat |
| L Studer, M Psylla, B Bühler, L Evtouchenko, C M Vouga, K L Leenders, R W Seiler, C Spenge. Noninvasive dopamine determination by reversed phase HPLC in the medium of free-floating roller tube cultures of rat fetal ventral mesencephalon: a tool to assess dopaminergic tissue prior to grafting. Brain research bulletin. vol 41. issue 3. 1997-02-07. PMID:8886383. |
noninvasive dopamine determination by reversed phase hplc in the medium of free-floating roller tube cultures of rat fetal ventral mesencephalon: a tool to assess dopaminergic tissue prior to grafting. |
1997-02-07 |
2023-08-12 |
rat |
| C K Chung, H J Kim, B S Jeon, Y S Kim, S B Lee, D H Ha. Unilateral fetal mesencephalic grafting in two patients with Parkinson's disease: short-term result after transplantation. No shinkei geka. Neurological surgery. vol 24. issue 11. 1997-02-04. PMID:8934466. |
in an effort to replenish the striatal dopaminergic innervation, fetal mesencephalic tissue containing dopamine cells was implanted into the unilateral putamen in two patients with severe parkinson's disease. |
1997-02-04 |
2023-08-12 |
Not clear |
| T Momiyama, T Amano, N Todo, M Sas. Inhibition by a putative antipsychotic quinolinone derivative (OPC-14597) of dopaminergic neurons in the ventral tegmental area. European journal of pharmacology. vol 310. issue 1. 1997-01-30. PMID:8880060. |
these results suggest that opc-14597 acts on dopaminergic neurons in the ventral tegmental area as a dopamine d2 receptor agonist to inhibit neuronal activities, probably by increasing membrane potassium conductance. |
1997-01-30 |
2023-08-12 |
rat |
| N B Mercuri, P Grillner, G Bernard. N-methyl-D-aspartate receptors mediate a slow excitatory postsynaptic potential in the rat midbrain dopaminergic neurons. Neuroscience. vol 74. issue 3. 1997-01-30. PMID:8884774. |
this n-methyl-d-aspartate-mediated synaptic event could be implicated in the release of dopamine as well as in the excitotoxic injury of the dopaminergic neurons. |
1997-01-30 |
2023-08-12 |
rat |
| D M Hagan, A N Brook. Dopaminergic regulation of adrenocorticotrophic hormone, alpha-melanocyte-stimulating hormone and cortisol secretion in the ovine fetus. The Journal of endocrinology. vol 151. issue 3. 1997-01-30. PMID:8994389. |
to test the hypothesis that the pars intermedia of the ovine fetal pituitary is under tonic inhibitory dopaminergic control we treated fetal sheep at day 131 of gestation with a 3-day intravenous infusion of one of the following: the dopamine antagonist sulpiride (0.3 mg/ 0.5 ml/h; n = 12), the dopamine agonist bromocriptine (0.03 mg/0.5 ml/h; n = 7) or vehicle (0.1 m tartaric acid in saline; n = 8) alone. |
1997-01-30 |
2023-08-12 |
Not clear |
| D P van Kammen, J P McEvoy, S D Targum, D Kardatzke, T B Sebre. A randomized, controlled, dose-ranging trial of sertindole in patients with schizophrenia. Psychopharmacology. vol 124. issue 1-2. 1997-01-29. PMID:8935813. |
sertindole is a novel antipsychotic agent with high selectivity for the mesolimbic dopaminergic pathway and nanomolar affinities for dopamine d2, serotonin 5-ht2, and norepinephrine ne alpha 1 receptors. |
1997-01-29 |
2023-08-12 |
Not clear |
| P V Piazza, M Barrot, F Rougé-Pont, M Marinelli, S Maccari, D N Abrous, H Simon, M Le Moa. Suppression of glucocorticoid secretion and antipsychotic drugs have similar effects on the mesolimbic dopaminergic transmission. Proceedings of the National Academy of Sciences of the United States of America. vol 93. issue 26. 1997-01-28. PMID:8986831. |
given that glucocorticoid hormones in animals increase dopamine release and dopamine-mediated behaviors and that high levels of glucocorticoids can induce psychotic symptoms in humans, these experiments examined whether inhibition of endogenous glucocorticoids might have apd-like effects on mesolimbic dopaminergic transmission in rats. |
1997-01-28 |
2023-08-12 |
rat |
| P V Piazza, M Barrot, F Rougé-Pont, M Marinelli, S Maccari, D N Abrous, H Simon, M Le Moa. Suppression of glucocorticoid secretion and antipsychotic drugs have similar effects on the mesolimbic dopaminergic transmission. Proceedings of the National Academy of Sciences of the United States of America. vol 93. issue 26. 1997-01-28. PMID:8986831. |
it is shown that suppression of glucocorticoid secretion by adrenalectomy profoundly decreased (by greater than 50%): (i) basal dopaminergic release and the release of dopamine induced by a depolarizing stimulus such as morphine (2 mg/kg, s.c.), as measured in the nucleus accumbens of freely moving animals by microdialysis; (ii) the locomotor activity induced by the direct dopaminergic agonist apomorphine. |
1997-01-28 |
2023-08-12 |
rat |
| J R Sanchez-Ramos, S Song, A Facca, A Basit, C J Epstei. Transgenic murine dopaminergic neurons expressing human Cu/Zn superoxide dismutase exhibit increased density in culture, but no resistance to methylphenylpyridinium-induced degeneration. Journal of neurochemistry. vol 68. issue 1. 1997-01-27. PMID:8978710. |
primary dopaminergic neuronal cultures with increased superoxide dismutase (sod) activity were established for studying the role of superoxide anion (o2-) in 1-methyl-4-phenylpyridinium (mpp+)-induced degeneration of dopamine (da) neurons. |
1997-01-27 |
2023-08-12 |
mouse |
| R A Huff, R A Vaughan, M J Kuhar, G R Uh. Phorbol esters increase dopamine transporter phosphorylation and decrease transport Vmax. Journal of neurochemistry. vol 68. issue 1. 1997-01-27. PMID:8978729. |
sodium- and chloride-coupled transport of dopamine from synapses into presynaptic terminals plays a key role in terminating dopaminergic neurotransmission. |
1997-01-27 |
2023-08-12 |
rat |
| R A Huff, R A Vaughan, M J Kuhar, G R Uh. Phorbol esters increase dopamine transporter phosphorylation and decrease transport Vmax. Journal of neurochemistry. vol 68. issue 1. 1997-01-27. PMID:8978729. |
phosphorylation of the dopamine transporter by pkc or by a pkc-activated kinase could be involved in rapid neuroadaptive processes in dopaminergic neurons. |
1997-01-27 |
2023-08-12 |
rat |
| M A De Souza Silva, C Mattern, R Häcker, P J Nogueira, J P Huston, R K Schwartin. Intranasal administration of the dopaminergic agonists L-DOPA, amphetamine, and cocaine increases dopamine activity in the neostriatum: a microdialysis study in the rat. Journal of neurochemistry. vol 68. issue 1. 1997-01-27. PMID:8978730. |
intranasal administration of the dopaminergic agonists l-dopa, amphetamine, and cocaine increases dopamine activity in the neostriatum: a microdialysis study in the rat. |
1997-01-27 |
2023-08-12 |
rat |
| J L Montastruc, O Rascol, J M Senar. New directions in the drug treatment of Parkinson's disease. Drugs & aging. vol 9. issue 3. 1997-01-21. PMID:8877311. |
slow-release preparations of levodopa, catechol-o-methyltransferase inhibitors and new dopamine agonists) or target clinical symptoms resistant to dopaminergic drugs (e.g. |
1997-01-21 |
2023-08-12 |
Not clear |
| R J Vermeulen, E C Wolters, G Tissingh, J Booij, A G Janssen, J Habraken, E Sokole-Busemann, J C Stoof, E A Van Roye. Evaluation of [123I] beta-CIT binding with SPECT in controls, early and late Parkinson's disease. Nuclear medicine and biology. vol 22. issue 8. 1997-01-17. PMID:8998476. |
the main neuropathological feature in parkinson's disease (pd) is a severe degeneration of the dopaminergic neurons in the substantia nigra resulting in a loss of dopamine in the striatum. |
1997-01-17 |
2023-08-12 |
Not clear |
| R J Vermeulen, E C Wolters, G Tissingh, J Booij, A G Janssen, J Habraken, E Sokole-Busemann, J C Stoof, E A Van Roye. Evaluation of [123I] beta-CIT binding with SPECT in controls, early and late Parkinson's disease. Nuclear medicine and biology. vol 22. issue 8. 1997-01-17. PMID:8998476. |
recently, a new radioligand (beta-cit) for single photon emission computed tomography (spect) became available for in vivo imaging of the dopamine transporter on nerve endings of dopaminergic neurons in the striatum. |
1997-01-17 |
2023-08-12 |
Not clear |
| A Python, Z de Saint Hilaire, J M Gaillar. Effects of a D2 receptor agonist RO 41-9067 alone and with clonidine on sleep parameters in the rat. Pharmacology, biochemistry, and behavior. vol 53. issue 2. 1997-01-16. PMID:8808134. |
an active role for d2 dopamine receptors and an interaction between noradrenergic and dopaminergic systems in the regulation of sleep is proposed. |
1997-01-16 |
2023-08-12 |
rat |
| L García, R de Miguel, J A Ramos, J J Fernàndez-Rui. Perinatal delta 9-tetrahydrocannabinol exposure in rats modifies the responsiveness of midbrain dopaminergic neurons in adulthood to a variety of challenges with dopaminergic drugs. Drug and alcohol dependence. vol 42. issue 3. 1997-01-16. PMID:8912798. |
in the second experiment, we evaluated the sensitivity of midbrain dopaminergic neurons to amphetamine (amph), which causes, through different mechanisms, a decrease in dopamine (da) metabolism. |
1997-01-16 |
2023-08-12 |
rat |
| A Dalia, N J Uretsky, L J Wallac. Induction of locomotor activity by the glutamate antagonist DNQX injected into the ventral tegmental area. Brain research. vol 728. issue 2. 1997-01-15. PMID:8864484. |
however, the locomotor stimulation produced by dnqx was markedly attenuated following blockade of dopaminergic receptors by haloperidol (0.5 mg/kg, s.c.) or following dopamine depletion induced by reserpine plus alpha-methyl-para-tyrosine pretreatment. |
1997-01-15 |
2023-08-12 |
Not clear |